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References from Injectable Hydrogel Loaded With Umbilical Cord Blood‐Derived Exosomes Promotes Periodontal Bone Regeneration via the TLR4/NF‐κB Signalling Pathway. Local targets link to admitted publications; unresolved targets remain external evidence.
GelMA@Ginsenoside Rb3 Targets Inflammatory Microenvironment in Periodontitis via MAPK Pathway
10.3390/gels11080648 · 2025 · External reference
Chronic Inflammation and Glycemic Control: Exploring the Bidirectional Link Between Periodontitis and Diabetes
10.3390/dj13030100 · 2025 · External reference
Persisting Chronic Periodontal Disease as a Risk Factor for Cardiovascular Disease: A Nationwide Population‐Based Cohort Study
10.1111/jcpe.14107 · 2025 · External reference
Probiotics as an Adjunctive Therapy in Periodontitis Treatment—Reality or Illusion—A Clinical Perspective
10.1038/s41522-024-00614-5 · 2024 · External reference
Photodynamic Therapy Adjuvant to Non‐Surgical Periodontal Therapy: Systematic Review of Randomized Clinical Trials
10.1111/idh.12759 · 2024 · External reference
Periodontitis: Etiology, Conventional Treatments, and Emerging Bacteriophage and Predatory Bacteria Therapies
10.3389/fmicb.2024.1469414 · 2024 · External reference
Periodontal Endoscopy for Mechanical Debridement in the Non‐Surgical Management of Peri‐Implantitis: A Narrative Review
10.3390/jcm14020346 · 2025 · External reference
Mechanistic Insights and Therapeutic Applications of Metal‐Based Nanomaterials in Oral Infectious Diseases: Current Advances and Future Perspectives
10.1016/j.biomaterials.2025.123528 · 2026 · External reference
The Role of Exosomes in Immunopathology and Potential Therapeutic Implications
10.1038/s41423-025-01323-5 · 2025 · External reference
The Biology, Function, and Biomedical Applications of Exosomes
10.1126/science.aau6977 · 2020 · External reference
Exosome‐Based Therapeutics in Bone Regeneration: From Fundamental Biology to Clinical Translation
10.1186/s13287-025-04686-8 · 2025 · External reference
Melatonin Engineering M2 Macrophage‐Derived Exosomes Mediate Endoplasmic Reticulum Stress and Immune Reprogramming for Periodontitis Therapy
10.1002/advs.202302029 · 2023 · External reference
Exosomes to Exosome‐Functionalized Scaffolds: A Novel Approach to Stimulate Bone Regeneration
10.1186/s13287-024-04024-4 · 2024 · External reference
3D‐Printed Titanium Trabecular Scaffolds With Sustained Release of Hypoxia‐Induced Exosomes for Dual‐Mimetic Bone Regeneration
10.1002/advs.202500599 · 2025 · External reference
A Blood Glucose Fluctuation‐Responsive Delivery System Promotes Bone Regeneration and the Repair Function of Smpd3‐Reprogrammed BMSC‐Derived Exosomes
10.1038/s41368-024-00328-6 · 2024 · External reference
Application of Cord Blood–Derived Exosomes in Tumor Prevention and Treatment
10.1177/11795549251365360 · 2025 · External reference
Extracellular Vesicles From Human Umbilical Cord Blood Ameliorate Bone Loss in Senile Osteoporotic Mice
10.1016/j.metabol.2019.01.009 · 2019 · External reference
Umbilical Cord Blood Plasma‐Derived Exosomes as a Novel Therapy to Reverse Liver Fibrosis
10.1186/s13287-021-02641-x · 2021 · External reference
MSC‐EVs and UCB‐EVs Promote Skin Wound Healing and Spatial Transcriptome Analysis
10.1038/s41598-025-87592-6 · 2025 · External reference
Umbilical Cord Blood‐Derived Exosomes Attenuate Dopaminergic Neuron Damage of Parkinson's Disease Mouse Model
2024 · External reference
Umbilical Cord Blood‐Derived Exosomes Deliver miR‐182‐5p to Therapeutically Target the MYD88/NF‐κB Signaling Pathway in Rat Peri‐Implantitis
10.1016/j.mtbio.2025.102246 · 2025 · External reference
Biological Features of Extracellular Vesicles and Challenges
10.3389/fcell.2022.816698 · 2022 · External reference
Tackling Exosome and Nuclear Receptor Interaction: An Emerging Paradigm in the Treatment of Chronic Diseases
10.1186/s40779-024-00564-1 · 2024 · External reference
3D‐Printed Vascularized Biofunctional Scaffold for Bone Regeneration
10.18063/ijb.702 · 2023 · External reference
Photocurable Platelet Rich Plasma Bioadhesives
10.1016/j.actbio.2020.09.030 · 2020 · External reference
Collagen Membrane and Immune Response in Guided Bone Regeneration: Recent Progress and Perspectives
10.1089/ten.teb.2016.0463 · 2017 · External reference
Minimal Information for Studies of Extracellular Vesicles (MISEV2023): From Basic to Advanced Approaches
10.1002/jev2.12404 · 2024 · External reference
Hypoxic Mesenchymal Stem Cell‐Derived Exosomes Promote Bone Fracture Healing by the Transfer of miR‐126
10.1016/j.actbio.2019.12.020 · 2020 · External reference
Human Umbilical Cord Mesenchymal Stem Cell‐Derived Exosomes Inhibit Inflammation and Fibrotic Scar Formation After Intracerebral Hemorrhage
10.1007/s11010-025-05259-2 · 2025 · External reference
Umbilical Cord‐Derived Exosomes Alleviate Spinal Cord Injury by Regulating Microglial Polarization Through miR‐340‐5p‐Mediated Modulation of the JAK/STAT3 Signaling Pathway
10.1038/s41598-025-16621-1 · 2025 · External reference
Defined MSC Exosome With High Yield and Purity to Improve Regenerative Activity
10.1177/20417314211008626 · 2021 · External reference
Immunomodulatory Properties of Umbilical Cord Blood‐Derived Small Extracellular Vesicles and Their Therapeutic Potential for Inflammatory Skin Disorders
10.3390/ijms22189797 · 2021 · External reference
Exosomes From Human Umbilical Cord Blood Accelerate Cutaneous Wound Healing Through miR‐21‐3p‐Mediated Promotion of Angiogenesis and Fibroblast Function
10.7150/thno.21234 · 2018 · External reference
Multifunctional Hydrogel Enhances Bone Regeneration Through Sustained Release of Stromal Cell‐Derived Factor‐1α and Exosomes
10.1016/j.bioactmat.2022.07.030 · 2023 · External reference
Exosomes‐Loaded Electroconductive Hydrogel Synergistically Promotes Tissue Repair After Spinal Cord Injury via Immunoregulation and Enhancement of Myelinated Axon Growth
10.1002/advs.202105586 · 2022 · External reference
Seamless and Early Gap Healing of Osteochondral Defects by Autologous Mosaicplasty Combined With Bioactive Supramolecular Nanofiber‐Enabled Gelatin Methacryloyl (BSN‐GelMA) Hydrogel
10.1016/j.bioactmat.2022.03.038 · 2023 · External reference
Self‐Healing Hydrogel Embodied With Macrophage‐Regulation and Responsive‐Gene‐Silencing Properties for Synergistic Prevention of Peritendinous Adhesion
10.1002/adma.202106564 · 2022 · External reference
A Biocompatible Hydrogel With Improved Stiffness and Hydrophilicity for Modular Tissue Engineering Assembly
10.1039/c5tb00129c · 2015 · External reference
Human Urine‐Derived Stem Cell Exosomes Delivered via Injectable GelMA Templated Hydrogel Accelerate Bone Regeneration
10.1016/j.mtbio.2023.100569 · 2023 · External reference
Photo‐Crosslinked Adhesive Hydrogel Loaded With Extracellular Vesicles Promoting Hemostasis and Liver Regeneration
10.3389/fbioe.2023.1170212 · 2023 · External reference
Yunnan Baiyao Regulates Th17/Treg Cell Homeostasis to Inhibit Periodontitis Through the miR‐155‐5p/ATG5 Pathway
10.1016/j.intimp.2025.115253 · 2025 · External reference
Egg‐Derived Tripeptide IRW Attenuates LPS‐Induced Osteoclastogenesis in RAW 264.7 Macrophages via Inhibition of Inflammatory Responses and NF‐κB/MAPK Activation
10.1021/acs.jafc.0c01159 · 2020 · External reference
Bone Marrow Mesenchymal Stem Cells‐Derived Exosomes Reduce Apoptosis and Inflammatory Response During Spinal Cord Injury by Inhibiting the TLR4/MyD88/NF‐κB Signaling Pathway
10.1177/09603271211003311 · 2021 · External reference
Bone Marrow Mesenchymal Stem Cell‐Derived Small Extracellular Vesicles Promote Periodontal Regeneration
10.1089/ten.tea.2020.0141 · 2021 · External reference
Exosomes Derived From 3D‐Cultured MSCs Improve Therapeutic Effects in Periodontitis and Experimental Colitis and Restore the Th17 Cell/Treg Balance in Inflamed Periodontium
10.1038/s41368-021-00150-4 · 2021 · External reference
Exosomes From TNF‐α‐Treated Human Gingiva‐Derived MSCs Enhance M2 Macrophage Polarization and Inhibit Periodontal Bone Loss
10.1016/j.actbio.2020.12.046 · 2021 · External reference
Chitosan Hydrogel Incorporated With Dental Pulp Stem Cell‐Derived Exosomes Alleviates Periodontitis in Mice via a Macrophage‐Dependent Mechanism
10.1016/j.bioactmat.2020.07.002 · 2020 · External reference
Exosomes Derived From Reparative M2‐Like Macrophages Prevent Bone Loss in Murine Periodontitis Models via IL‐10 mRNA
2022 · External reference
Roles of Osteoclasts in Alveolar Bone Remodeling
10.1002/dvg.23490 · 2022 · External reference
Functional Differences of Toll‐Like Receptor 4 in Osteogenesis, Adipogenesis and Chondrogenesis in Human Bone Marrow‐Derived Mesenchymal Stem Cells
10.1111/jcmm.16506 · 2021 · External reference
MiR‐137 Promotes TLR4/NF‐κB Pathway Activity Through Targeting KDM4A, Inhibits Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells and Aggravates Osteoporosis
10.1186/s13018-023-03918-y · 2023 · External reference
O‐GlcNAcylation of TLR4 Inhibits Osteogenic Differentiation of Periodontal Ligament Stem Cells
10.1111/jre.13193 · 2024 · External reference
Avicularin Alleviates Osteoporosis in Ovariectomized Mice by Inhibiting Osteoclastogenesis Through NF‐κB Pathway Inhibition
10.1021/acs.jafc.2c05954 · 2023 · External reference
Phospholipase D2 Drives Mortality in Sepsis by Inhibiting Neutrophil Extracellular Trap Formation and Down‐Regulating CXCR2
10.1084/jem.20141813 · 2015 · External reference