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10.1111/jcpe.13807 · 2023 · External reference

Apabetalone (RVX‐208): A Potential Epigenetic Therapy for the Treatment of Cardiovascular, Renal, Neurological, Viral, and Cancer Disorders

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Effect of the BET Protein Inhibitor, RVX‐208, on Progression of Coronary Atherosclerosis: Results of the Phase 2b, Randomized, Double‐Blind, Multicenter, ASSURE Trial

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Selective BET Protein Inhibition With Apabetalone and Cardiovascular Events: A Pooled Analysis of Trials in Patients With Coronary Artery Disease

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Apabetalone and Hospitalization for Heart Failure in Patients Following an Acute Coronary Syndrome: A Prespecified Analysis of the BETonMACE Study

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Effects of the BET‐Inhibitor, RVX‐208 on the HDL Lipidome and Glucose Metabolism in Individuals With Prediabetes: A Randomized Controlled Trial

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RVX‐208, An Inhibitor of BET Transcriptional Regulators With Selectivity for the Second Bromodomain

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RVX‐208, An Inducer of ApoA‐I in Humans, Is a BET Bromodomain Antagonist

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Effect of Apabetalone Added to Standard Therapy on Major Adverse Cardiovascular Events in Patients With Recent Acute Coronary Syndrome and Type 2 Diabetes: A Randomized Clinical Trial

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Selective BET Inhibitor RVX‐208 Ameliorates Periodontal Inflammation and Bone Loss

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BET Inhibitor JQ1 Blocks Inflammation and Bone Destruction

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Nonselective Inhibition of the Epigenetic Transcriptional Regulator BET Induces Marked Lymphoid and Hematopoietic Toxicity in Mice

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Apabetalone Alleviates Ligature‐Induced Periodontitis by Inhibiting M1 Macrophage Polarization Via An Immunometabolic Shift

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Histone Acetylation, BET Proteins, and Periodontal Inflammation

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Macrophage Immunomodulation in Chronic Osteolytic Diseases—The Case of Periodontitis

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The Secretion of Cytokines by Peripheral Blood Mononuclear Cells of Patients With Periodontitis and Healthy Controls When Exposed to H(2)S

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Blocking Proinflammatory Cytokine Release Modulates Peripheral Blood Mononuclear Cell Response to Porphyromonas gingivalis

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Release of Cytokines by Stimulated Peripheral Blood Mononuclear Cells in Chronic Periodontitis

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Peripheral Blood Mononuclear Phagocytes From Patients With Chronic Periodontitis Are Primed for Osteoclast Formation

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Interleukin‐6 Expression and Gene Polymorphism Are Associated With Severity of Periodontal Disease in a Sample of Brazilian Individuals

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Local and Systemic Mechanisms Linking Periodontal Disease and Inflammatory Comorbidities

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Diagnostic and Prognostic Ability of Salivary MMP‐9 and S100A8 for Periodontitis

10.1111/jcpe.13349 · 2020 · External reference

Interleukin‐1beta is a Potential Therapeutic Target for Periodontitis: A Narrative Review

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Inflammasome Targeting for Periodontitis Prevention is Sex Dependent

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Porphyromonas gingivalis ‐Induced Production of Reactive Oxygen Species, Tumor Necrosis Factor‐Alpha, Interleukin‐6, CXCL8 and CCL2 by Neutrophils From Localized Aggressive Periodontitis and Healthy Donors: Modulating Actions of Red Blood Cells and Resolvin E1

10.1111/jre.12388 · 2017 · External reference

BET Protein Inhibitor Apabetalone (RVX‐208) Suppresses Pro‐Inflammatory Hyper‐Activation of Monocytes From Patients With Cardiovascular Disease and Type 2 Diabetes

10.1186/s13148-020-00943-0 · 2020 · External reference

Downregulation of the Complement Cascade In Vitro, in Mice and in Patients With Cardiovascular Disease by the BET Protein Inhibitor Apabetalone (RVX‐208)

10.1007/s12265-017-9755-z · 2017 · External reference

RVX‐208: A Small Molecule That Increases Apolipoprotein A‐I and High‐Density Lipoprotein Cholesterol In Vitro and In Vivo

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Benefit of Apabetalone on Plasma Proteins in Renal Disease

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A Novel BET Bromodomain Inhibitor, RVX‐208, Shows Reduction of Atherosclerosis in Hyperlipidemic ApoE Deficient Mice

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BET‐Induced Metabolic Reprogramming Fuels Inflammation at the Vascular‐Fat Interface in Mice and Patients With Cardiometabolic Disease

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Selective Targeting of BD1 and BD2 of the BET Proteins in Cancer and Immunoinflammation

10.1126/science.aaz8455 · 2020 · External reference

Breaking Boundaries: Pan BETi Disrupt 3D Chromatin Structure, BD2‐Selective BETi Are Strictly Epigenetic Transcriptional Regulators

10.1016/j.biopha.2022.113230 · 2022 · External reference

An Experimental Murine Model to Study Periodontitis

10.1038/s41596-018-0035-4 · 2018 · External reference

Heritability of Periodontal Bone Loss in Mice

10.1111/jre.12258 · 2015 · External reference

MAPK Usage in Periodontal Disease Progression

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Actinobacillus actinomycetemcomitans Lipopolysaccharide‐Mediated Experimental Bone Loss Model for Aggressive Periodontitis

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Differential Cytokine Patterns in Mouse Macrophages and Gingival Fibroblasts After Stimulation With Porphyromonas Gingivalis or Escherichia coli Lipopolysaccharide

10.1902/jop.2010.100226 · 2010 · External reference

Genomewide Association Study Identifies Cxcl Family Members as Partial Mediators of LPS‐Induced Periodontitis

10.1002/jbmr.3440 · 2018 · External reference

A Murine Model of Lipopolysaccharide‐Induced Peri‐Implant Mucositis and Peri‐Implantitis

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