Research graph
References from Transdiagnostic patterns of electroencephalography ( <scp>EEG</scp> )‐derived aperiodic activity across schizophrenia‐spectrum, bipolar, and depressive disorders: A systematic review. Local targets link to admitted publications; unresolved targets remain external evidence.
The RDoC framework: Facilitating transition from ICD/DSM to dimensional approaches that integrate neuroscience and psychopathology
10.1002/wps.20087 · 2014 · External reference
Identification of a common neurobiological substrate for mental illness
10.1001/jamapsychiatry.2014.2206 · 2015 · External reference
The p factor: One general psychopathology factor in the structure of psychiatric disorders?
10.1177/2167702613497473 · 2014 · External reference
The hierarchical taxonomy of psychopathology (HiTOP): A quantitative nosology based on consensus of evidence
10.1146/annurev-clinpsy-081219-093304 · 2021 · External reference
Psychopathology and the human connectome: Toward a Transdiagnostic model of risk for mental illness
10.1016/j.neuron.2012.06.002 · 2012 · External reference
Toward the future of psychiatric diagnosis: The seven pillars of RDoC
10.1186/1741-7015-11-126 · 2013 · External reference
Excitation‐inhibition balance as a framework for investigating mechanisms in neuropsychiatric disorders
10.1038/s41380-019-0426-0 · 2019 · External reference
Brain‐wide changes in excitation‐inhibition balance of major depressive disorder: A systematic review of topographic patterns of GABA‐ and glutamatergic alterations
10.1038/s41380-023-02193-x · 2023 · External reference
Searching for cross‐diagnostic convergence: Neural mechanisms governing excitation and inhibition balance in schizophrenia and autism Spectrum disorders
10.1016/j.biopsych.2017.03.005 · 2017 · External reference
Dynamic balance of excitation and inhibition in human and monkey neocortex
10.1038/srep23176 · 2016 · External reference
Prefrontal excitatory/inhibitory balance in stress and emotional disorders: Evidence for over‐inhibition
10.1016/j.neubiorev.2019.07.024 · 2019 · External reference
Dysregulation of glutamatergic and GABAergic neurons in treatment‐resistant depression: Insights from patient‐derived neurons
10.1016/j.pnpbp.2025.111527 · 2025 · External reference
Cognitive deficits and functional outcomes in major depressive disorder: Determinants, substrates, and treatment interventions
10.1002/da.22063 · 2013 · External reference
Cognitive impairment in schizophrenia: Aetiology, pathophysiology, and treatment
10.1038/s41380-023-01949-9 · 2023 · External reference
Cognitive impairment in depression: Recent advances and novel treatments
10.2147/ndt.s199746 · 2019 · External reference
Cognitive impairments in treatment‐resistant depression: Results from the French cohort of outpatients (FACE‐DR)
2021 · External reference
Resting‐state functional connectivity of salience network in schizophrenia and depression
10.1038/s41598-022-15489-9 · 2022 · External reference
Impaired emotion regulation in schizophrenia: Evidence from event‐related potentials
10.1017/s0033291713000019 · 2013 · External reference
Altered neural activities during emotion regulation in depression: A meta‐analysis
10.1503/jpn.240046 · 2024 · External reference
The sleep‐circadian interface: A window into mental disorders
10.1073/pnas.2214756121 · 2024 · External reference
Aberrant brain dynamics of large‐scale functional networks across schizophrenia and mood disorder
10.1016/j.nicl.2024.103574 · 2024 · External reference
Prevalence of comorbid depression in schizophrenia: A meta‐analysis of observational studies
10.1016/j.jad.2020.04.056 · 2020 · External reference
Epidemiology of psychotic depression ‐ systematic review and meta‐analysis
10.1017/s0033291717002501 · 2018 · External reference
Cerebello‐Thalamo‐cortical Dysconnectivity in schizophrenia Spectrum disorders: A resting‐state functional magnetic resonance imaging meta‐analysis
2026 · External reference
Resting‐state functional connectivity in treatment‐resistant depression
10.1176/appi.ajp.2010.10101419 · 2011 · External reference
Cortico‐limbic network abnormalities in individuals with current and past major depressive disorder
10.1016/j.jad.2014.10.041 · 2015 · External reference
Neurophysiology and regulation of the balance between excitation and inhibition in neocortical circuits
10.1016/j.biopsych.2016.09.017 · 2017 · External reference
Imprecise predictive coding is at the Core of classical schizophrenia
10.3389/fnhum.2022.818711 · 2022 · External reference
Resting‐state dynamic functional connectivity in major depressive disorder: A systematic review
10.1016/j.pnpbp.2024.111076 · 2024 · External reference
Trait and state‐related characteristics of thalamo‐cortical circuit disruption in bipolar disorder: A prospective cross‐sectional study
10.3389/fpsyt.2023.1067819 · 2023 · External reference
Decoding neural circuit dysregulation in bipolar disorder: Toward an advanced paradigm for multidimensional cognitive, emotional, and psychomotor treatment
10.1016/j.neubiorev.2025.106030 · 2025 · External reference
Parvalbumin interneuron deficits in schizophrenia
10.1016/j.euroneuro.2024.02.010 · 2024 · External reference
Frontocingulate dysfunction in depression: Toward biomarkers of treatment response
10.1038/npp.2010.166 · 2011 · External reference
Unveiling major depressive disorder through TMS‐EEG: From traditional to emerging approaches
2025 · External reference
Depressive symptomatology in the first‐episode schizophrenia spectrum disorders OPTiMiSE trial: Prevalence, correlates, symptom progression and outcomes
10.1038/s41537-025-00681-3 · 2025 · External reference
Excitation/inhibition imbalance in schizophrenia: A meta‐analysis of inhibitory and excitatory TMS‐EMG paradigms
10.1038/s41537-024-00476-y · 2024 · External reference
Major depressive disorder: Hypothesis, mechanism, prevention and treatment
10.1038/s41392-024-01738-y · 2024 · External reference
Excitatory and inhibitory synaptic dysfunction in mania: An emerging hypothesis from animal model studies
2018 · External reference
Inferring synaptic excitation/inhibition balance from field potentials
10.1016/j.neuroimage.2017.06.078 · 2017 · External reference
Aperiodic (1/f) neural activity robustly tracks symptom severity changes in treatment‐resistant depression
2025 · External reference
The origin of extracellular fields and currents — EEG, ECoG, LFP and spikes
10.1038/nrn3241 · 2012 · External reference
Parameterizing neural power spectra into periodic and aperiodic components
10.1038/s41593-020-00744-x · 2020 · External reference
How inhibition shapes cortical activity
10.1016/j.neuron.2011.09.027 · 2011 · External reference
Separating neural oscillations from aperiodic 1/f activity: Challenges and recommendations
10.1007/s12021-022-09581-8 · 2022 · External reference
Ketamine and rapid antidepressant action: New treatments and novel synaptic signaling mechanisms
10.1038/s41386-023-01629-w · 2024 · External reference
Association of Ketamine with Psychiatric Symptoms and Implications for its therapeutic use and for understanding schizophrenia: A systematic review and meta‐analysis
10.1001/jamanetworkopen.2020.4693 · 2020 · External reference
A systematic review of aperiodic neural activity in clinical investigations
10.1111/ejn.70255 · 2025 · External reference
The PRISMA 2020 statement: An updated guideline for reporting systematic reviews
10.1136/bmj.n71 · 2021 · External reference
PRISMA 2020 explanation and elaboration: Updated guidance and exemplars for reporting systematic reviews
10.1136/bmj.n160 · 2021 · External reference
Unresolved reference
External reference
Unresolved reference
External reference
Large‐scale maps of altered cortical dynamics in early‐stage psychosis are related to GABAergic and glutamatergic neurotransmission
10.1126/sciadv.ads0400 · 2025 · External reference
RoB 2: A revised tool for assessing risk of bias in randomised trials
10.1136/bmj.l4898 · 2019 · External reference
The Cochrane Collaboration's tool for assessing risk of bias in randomised trials
10.1136/bmj.d5928 · 2011 · External reference
ROBINS‐I: A tool for assessing risk of bias in non‐randomised studies of interventions
10.1136/bmj.i4919 · 2016 · External reference
Unresolved reference
External reference
Power signatures of habenular neuronal signals in patients with bipolar or unipolar depressive disorders correlate with their disease severity
10.1038/s41398-022-01830-3 · 2022 · External reference
Esketamine disinhibits brain networks in depression: Evidence from oscillatory and aperiodic activity
10.1016/j.pnpbp.2025.111438 · 2025 · External reference
Field potential 1/f activity in the subcallosal cingulate region as a candidate signal for monitoring deep brain stimulation for treatment‐resistant depression
10.1152/jn.00875.2018 · 2019 · External reference
Increased aperiodic neural activity during sleep in major depressive disorder
10.1016/j.bpsgos.2022.10.001 · 2023 · External reference
Magnetic seizure therapy and electroconvulsive therapy increase aperiodic activity
10.1038/s41398-023-02631-y · 2023 · External reference
Predictive biomarkers of treatment response in major depressive disorder
10.3390/brainsci13111570 · 2023 · External reference
Ketamine alters the aperiodic EEG exponent in major depression: Implications for cortical E/I balance and treatment prediction
10.1177/20451253261462240 · 2026 · External reference
The role of frontal EEG in predicting clinical response of major depressive disorder to intranasal ketamine and esketamine
10.1016/j.jad.2025.120751 · 2026 · External reference
Periodic and aperiodic alterations of resting‐state EEG in schizophrenia Spectrum disorders: Cognitive and clinical insights
10.1111/ejn.70263 · 2025 · External reference
Aperiodic neural activity is a better predictor of schizophrenia than neural oscillations
10.1177/15500594231165589 · 2023 · External reference
Memantine effects on electroencephalographic measures of putative excitatory/inhibitory balance in schizophrenia
2020 · External reference
The scanner as the stimulus: Deficient gamma‐BOLD coupling in schizophrenia at rest
10.1093/schbul/sbad014 · 2023 · External reference
Separating scale‐free and oscillatory components of neural activity in schizophrenia
10.1002/brb3.2047 · 2021 · External reference
Exploring aperiodic activity in first episode schizophrenia spectrum psychosis: A resting‐state EEG analysis
10.1016/j.brainres.2024.149052 · 2024 · External reference
The contribution of gamma bursting to spontaneous gamma activity in schizophrenia
10.3389/fnhum.2023.1130897 · 2023 · External reference
Reduced temporal variability of cortical excitation/inhibition ratio in schizophrenia
10.1038/s41537-025-00568-3 · 2025 · External reference
The aperiodic and periodic activities of EEG dynamically relate with cognitive performance in schizophrenia
10.1016/j.scog.2025.100383 · 2025 · External reference
Assessing trial‐by‐trial electrophysiological and behavioral markers of attentional control and sensory precision in psychotic and mood disorders
10.1093/schbul/sbae038 · 2025 · External reference
The self and its prolonged intrinsic neural timescale in schizophrenia
10.1093/schbul/sbaa083 · 2020 · External reference
Profiling electrophysiological and linguistic markers: Implications for clinical and functional outcome in schizophrenia
10.1016/j.neuropsychologia.2025.109343 · 2026 · External reference
Resting‐state EEG alterations of practice‐related spectral activity and connectivity patterns in depression
2024 · External reference
Alterations in aperiodic neural activity associated with major depressive disorder
10.1038/s44220-025-00494-4 · 2025 · External reference
Implications of aperiodic and periodic EEG components in classification of major depressive disorder from source and electrode perspectives
10.3390/s24186103 · 2024 · External reference
EEG unpredictability in the resting state of major depressive disorder: A multidomain EEG analysis
10.1007/s10548-026-01176-9 · 2026 · External reference
Individualized spectral features in first‐episode and drug‐naïve major depressive disorder: Insights from periodic and aperiodic electroencephalography analysis
2025 · External reference
Neural sleep signatures in major depressive disorder: Altered oscillatory and aperiodic components
10.1016/j.neuroimage.2026.121788 · 2026 · External reference
Neurophysiological correlates of ketamine‐induced dissociative state in bipolar disorder: Insights from real‐world clinical settings
10.1038/s41380-025-02889-2 · 2025 · External reference
Clinical EEG slowing induced by electroconvulsive therapy is better described by increased frontal aperiodic activity
10.1038/s41398-023-02634-9 · 2023 · External reference
Investigating cognitive flexibility deficit in schizophrenia using task‐based whole‐brain functional connectivity
10.3389/fpsyt.2022.1069036 · 2022 · External reference
Abnormal dynamic reconfiguration of the large‐scale functional network in schizophrenia during the episodic memory task
10.1093/cercor/bhac331 · 2023 · External reference
Dysfunction of large‐scale brain networks in schizophrenia: A meta‐analysis of resting‐state functional connectivity
10.1093/schbul/sbx034 · 2018 · External reference
The neural underpinnings of cognitive flexibility and their disruption in psychotic illness
10.1016/j.neuroscience.2016.06.005 · 2017 · External reference
Distinct hierarchical alterations of intrinsic neural timescales account for different manifestations of psychosis
10.7554/elife.56151 · 2020 · External reference
Imbalance of default mode and regulatory networks during externally focused processing in depression
10.1093/scan/nsu117 · 2015 · External reference
Depressive rumination, the default‐mode network, and the dark matter of clinical neuroscience
10.1016/j.biopsych.2015.02.020 · 2015 · External reference
20 years of the default mode network: A review and synthesis
10.1016/j.neuron.2023.04.023 · 2023 · External reference
The burden of depressive symptoms in the long‐term treatment of patients with schizophrenia
10.1016/j.schres.2006.09.027 · 2007 · External reference
Depression and schizophrenia: Cause, consequence, or trans‐diagnostic issue?
2017 · External reference
Exploring depression in people with schizophrenia spectrum disorders: A cross‐sectional analysis of the clinical relationship with positive and negative syndrome scale dimensions
2024 · External reference
Resting GABA concentration predicts peak gamma frequency and fMRI amplitude in response to visual stimulation in humans
10.1073/pnas.0900728106 · 2009 · External reference
Neurophysiological investigation of the basis of the fMRI signal
10.1038/35084005 · 2001 · External reference
Endogenous brain oscillations and related networks detected by surface EEG‐combined fMRI
10.1002/hbm.20600 · 2008 · External reference
