Research graph
References from Growth factor polygenic disposition shapes associations of childhood adversity with gray matter and clinical profiles in depression: A two‐cohort imaging‐genetics study. Local targets link to admitted publications; unresolved targets remain external evidence.
Early or recent trauma in treatment‐resistant depression: A systematic review
10.1017/s1092852925000185 · 2025 · External reference
The effects of childhood trauma on the onset, severity and improvement of depression: The role of dysfunctional attitudes and cortisol levels
10.1016/j.jad.2020.07.023 · 2020 · External reference
Adverse childhood experiences and treatment‐resistant depression
10.1001/jamanetworkopen.2026.0222 · 2026 · External reference
Understanding heterogeneity in grey matter research of adults with childhood maltreatment—A meta‐analysis and review
10.1016/j.neubiorev.2016.08.011 · 2016 · External reference
The effects of childhood maltreatment on brain structure, function and connectivity
10.1038/nrn.2016.111 · 2016 · External reference
Multimodal brain‐derived subtypes of major depressive disorder differentiate patients for anergic symptoms, immune‐inflammatory markers, history of childhood trauma and treatment‐resistance
10.1016/j.euroneuro.2024.05.015 · 2024 · External reference
Structural brain characteristics in treatment‐resistant depression: Review of magnetic resonance imaging studies
10.1192/bjo.2019.58 · 2019 · External reference
The devastating clinical consequences of child abuse and neglect: Increased disease vulnerability and poor treatment response in mood disorders
10.1176/appi.ajp.19010020 · 2023 · External reference
Beyond diathesis stress: Differential susceptibility to environmental influences
10.1037/a0017376 · 2009 · External reference
Gray matter correlates of childhood maltreatment lack replicability in a multi‐cohort brain‐wide association study
10.1038/s41467-025-62374-w · 2025 · External reference
The psychological factors mediating/moderating the association between childhood adversity and depression: A systematic review
10.1016/j.neubiorev.2022.104663 · 2022 · External reference
Functions of neurotrophins and growth factors in neurogenesis and brain repair
10.1002/cyto.a.22161 · 2013 · External reference
Neurotrophin regulation of neural circuit development and function
10.1038/nrn3379 · 2013 · External reference
Brain‐derived neurotrophic factor signaling in depression and antidepressant action
10.1016/j.biopsych.2021.05.008 · 2021 · External reference
A neurotrophic model for stress‐related mood disorders
10.1016/j.biopsych.2006.02.013 · 2006 · External reference
Alterations in the levels of growth factors in adolescents with major depressive disorder: A longitudinal study during the treatment with fluoxetine
10.1155/2019/9130868 · 2019 · External reference
Peripheral vascular endothelial growth factor as a novel depression biomarker: A meta‐analysis
10.1016/j.psyneuen.2015.07.002 · 2015 · External reference
Decreased serum hepatocyte growth factor (HGF) in individuals with depression correlates with severity of disease
10.4137/bmi.s5183 · 2010 · External reference
Stem cell factor (SCF) is a putative biomarker of antidepressant response
10.1007/s11481-016-9672-y · 2016 · External reference
VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants
10.1073/pnas.0610282104 · 2007 · External reference
Genome‐wide DNA methylation levels and altered cortisol stress reactivity following childhood trauma in humans
10.1038/ncomms10967 · 2016 · External reference
Childhood adversity and risk of suicide: Cohort study of 548 721 adolescents and young adults in Sweden
10.1136/bmj.j1334 · 2017 · External reference
Childhood trauma cortisol and immune cell glucocorticoid transcript levels are associated with increased risk for suicidality in adolescence
10.1038/s41380-025-02923-3 · 2025 · External reference
Differential impact of met receptor gene interaction with early‐life stress on neuronal morphology and behavior in mice
10.1016/j.ynstr.2017.11.003 · 2018 · External reference
Longitudinal DNA methylation changes at MET may alter HGF/c‐MET signalling in adolescents at risk for depression
10.1080/15592294.2019.1700628 · 2020 · External reference
The genomic architecture of circulating cytokine levels points to drug targets for immune‐related diseases
10.1038/s42003-025-07453-w · 2025 · External reference
Polygenic risk scores: From research tools to clinical instruments
10.1186/s13073-020-00742-5 · 2020 · External reference
Stratification of individuals with lifetime depression and low wellbeing in the UK biobank
10.1016/j.jad.2022.07.023 · 2022 · External reference
Depressive symptoms and neuroticism‐related traits are the main factors associated with wellbeing independent of the history of lifetime depression in the UK biobank
10.1017/s003329172100502x · 2023 · External reference
The PHQ‐9: Validity of a brief depression severity measure
10.1046/j.1525-1497.2001.016009606.x · 2001 · External reference
Early environment, emotions, responses to stress, and health
10.1111/j.1467-6494.2004.00300.x · 2004 · External reference
A RATING SCALE FOR DEPRESSION
10.1136/jnnp.23.1.56 · 1960 · External reference
A Delphi‐method‐based consensus guideline for definition of treatment‐resistant depression for clinical trials
10.1038/s41380-021-01381-x · 2022 · External reference
Ein Screeninginstrument für Missbrauch und Vernachlässigung in der Kindheit: der Childhood Trauma Screener (CTS)
10.1055/s-0031-1298984 · 2012 · External reference
LDpred2: better, faster, stronger
10.1093/bioinformatics/btaa1029 · 2021 · External reference
Adjusting batch effects in microarray expression data using empirical Bayes methods
10.1093/biostatistics/kxj037 · 2007 · External reference
Image processing and quality control for the first 10,000 brain imaging datasets from UK biobank
10.1016/j.neuroimage.2017.10.034 · 2018 · External reference
Unresolved reference
2013 · External reference
The definition and meaning of treatment‐resistant depression
2001 · External reference
HGF and MET: From brain development to neurological disorders
10.3389/fcell.2021.683609 · 2021 · External reference
The association of stem cell factor and soluble c‐kit (s‐cKit) receptor serum concentrations with the severity and risk prediction of autism spectrum disorders
10.1007/s11011-021-00883-5 · 2022 · External reference
Tyrosine kinases: Multifaceted receptors at the intersection of several neurodegenerative disease‐associated processes
10.3389/frdem.2024.1458038 · 2024 · External reference
Stem cell factor receptor/c‐kit: From basic science to clinical implications
10.1152/physrev.00046.2011 · 2012 · External reference
Physiology and neurobiology of stress and adaptation: Central role of the brain
10.1152/physrev.00041.2006 · 2007 · External reference
Stem cell factor and its receptor c‐kit as targets for inflammatory diseases
10.1016/j.ejphar.2005.12.067 · 2006 · External reference
Inhibition of apoptosis‐inducing factor translocation is involved in protective effects of hepatocyte growth factor against excitotoxic cell death in cultured hippocampal neurons
10.1111/j.1471-4159.2005.03446.x · 2005 · External reference
Acute hepatocyte growth factor treatment induces long‐term neuroprotection and stroke recovery via mechanisms involving neural precursor cell proliferation and differentiation
10.1038/jcbfm.2010.211 · 2011 · External reference
A systematic review and meta‐analysis of clinical studies on major depression and BDNF levels: Implications for the role of neuroplasticity in depression
10.1017/s1461145708009309 · 2008 · External reference
Functional connectivity of the right inferior frontal gyrus and orbitofrontal cortex in depression
10.1093/scan/nsaa014 · 2020 · External reference
Dissociable intrinsic connectivity networks for salience processing and executive control
10.1523/jneurosci.5587-06.2007 · 2007 · External reference
Episodic memory retrieval, parietal cortex, and the default mode network: Functional and topographic analyses
10.1523/jneurosci.3335-10.2011 · 2011 · External reference
The parahippocampal gyrus links the default‐mode cortical network with the medial temporal lobe memory system
10.1002/hbm.22234 · 2014 · External reference
Understanding heterogeneity in clinical cohorts using normative models: Beyond case‐control studies
10.1016/j.biopsych.2015.12.023 · 2016 · External reference
Effect of early stress on hippocampal gray matter is influenced by a functional polymorphism in EAAT2 in bipolar disorder
10.1016/j.pnpbp.2014.01.021 · 2014 · External reference
Childhood adversity is associated with reduced threat‐safety discrimination and increased fear generalization in 12‐ to 16‐year‐olds
10.1111/jcpp.14092 · 2025 · External reference
Depressive rumination, the default‐mode network, and the dark matter of clinical neuroscience
10.1016/j.biopsych.2015.02.020 · 2015 · External reference
Longitudinal associations between rumination and depressive symptoms in a probability sample of adults
10.1016/j.jad.2019.09.035 · 2020 · External reference
Understanding the association between adverse childhood experiences and subsequent attention deficit hyperactivity disorder: A systematic review and meta‐analysis of observational studies
10.1002/brb3.2748 · 2022 · External reference
Adult ADHD and comorbid anxiety and depressive disorders: A review of etiology and treatment
10.3389/fpsyt.2025.1597559 · 2025 · External reference
Brain‐charting autism and attention‐deficit/hyperactivity disorder reveals distinct and overlapping neurobiology
10.1016/j.biopsych.2024.07.024 · 2025 · External reference
