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References from Photobiomodulation alters base excision repair gene expression in an experimental model of arthritis. Local targets link to admitted publications; unresolved targets remain external evidence.
Rheumatoid arthritis
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Rheumatoid arthritis: pathogenic roles of diverse immune cells
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Global, regional, and national burden of osteoarthritis, 1990‐2020 and projections to 2050: a systematic analysis for the global burden of disease study 2021
10.1016/s2665-9913(23)00163-7 · 2023 · External reference
A review on the epidemiology of rheumatoid arthritis: an update and trends from current literature
10.1016/j.berh.2025.102036 · 2025 · External reference
Osteoarthritis: pathology, diagnosis, and treatment options
10.1016/j.mcna.2019.10.007 · 2020 · External reference
Rheumatoid arthritis
10.1038/nrdp.2018.1 · 2018 · External reference
Cytokines and chemokines involved in osteoarthritis pathogenesis
10.3390/ijms22179208 · 2021 · External reference
Cytokine networks in the pathogenesis of rheumatoid arthritis
10.3390/ijms222010922 · 2021 · External reference
Osteoarthritis
10.1016/s0140-6736(14)60802-3 · 2015 · External reference
Osteoarthritis
10.1016/s0140-6736(19)30417-9 · 2019 · External reference
The mechanisms and efficacy of photobiomodulation therapy for arthritis: a comprehensive review
10.3390/ijms241814293 · 2023 · External reference
Apoptosis induced by low‐level laser in polymorphonuclear cells of acute joint inflammation: comparative analysis of two energy densities
10.1007/s10103-017-2196-8 · 2017 · External reference
Low level laser therapy (classes I, II and III) for treating rheumatoid arthritis
2005 · External reference
Current advances of photobiomodulation therapy in treating knee osteoarthritis
10.3389/fcell.2023.1286025 · 2023 · External reference
Light‐emitting diode photobiomodulation on rheumatoid arthritis and osteoarthritis: in vitro and in vivo studies
10.1111/php.70077 · 2026 · External reference
Low level light effects on inflammatory cytokine production by rheumatoid arthritis synoviocytes
10.1002/lsm.20766 · 2009 · External reference
Photobiomodulation with 630‐nm LED radiation inhibits the proliferation of human synoviocyte MH7A cells possibly via TRPV4/PI3K/AKT/mTOR signaling pathway
10.1007/s10103-020-02977-5 · 2020 · External reference
Low‐level laser therapy for rheumatoid arthritis: a review of experimental approaches
10.34172/jlms.2022.62 · 2022 · External reference
Photobiomodulation ameliorates inflammatory parameters in fibroblast‐like synoviocytes and experimental animal models of rheumatoid arthritis
10.3389/fimmu.2023.1122581 · 2023 · External reference
Efficacy of low‐level laser therapy on pain and disability in knee osteoarthritis: systematic review and meta‐analysis of randomised placebo‐controlled trials
10.1136/bmjopen-2019-031142 · 2019 · External reference
Photobiomodulation for the treatment of knee osteoarthritis: therapeutic effects and molecular mechanism
10.3389/fcell.2026.1744761 · 2026 · External reference
Effects of Photobiomodulation on osteoarthritis from in vivo and in vitro studies: a narrative review
10.3390/ijms26188997 · 2025 · External reference
High‐frequency near‐infrared diode laser irradiation suppresses IL‐1β‐induced inflammatory cytokine expression and NF‐κB signaling pathways in human primary chondrocytes
10.1007/s10103-021-03371-5 · 2022 · External reference
BMP4 up‐regulated by 630 nm LED irradiation is associated with the amelioration of rheumatoid arthritis
10.1016/j.jphotobiol.2023.112828 · 2024 · External reference
Photobiomodulation control the expression of MMP, TNF‐α and NK‐1 receptors, improving allodynia and cartilage resistance in rheumatoid arthritis model
10.1007/s10103-025-04557-x · 2025 · External reference
Photobiomodulation therapy associated with treadmill training in the oxidative stress in a collagen‐induced arthritis model
10.1007/s10103-017-2209-7 · 2017 · External reference
Effects of low‐level laser therapy in adults with rheumatoid arthritis: a systematic review and meta‐analysis of controlled trials
10.1371/journal.pone.0291345 · 2023 · External reference
Resistance exercise and low‐level laser therapy improves grip strength and morphological aspects in the ankle joint of Wistar rats with experimental arthritis
10.1002/ar.25112 · 2023 · External reference
Increased reactive oxygen species formation and oxidative stress in rheumatoid arthritis
10.1371/journal.pone.0152925 · 2016 · External reference
Reactive oxygen species and serum antioxidant defense in juvenile idiopathic arthritis
10.1007/s10067-014-2571-9 · 2015 · External reference
Oxidant/antioxidant status of plasma samples from patients with rheumatoid arthritis
10.1007/s002960050097 · 1999 · External reference
Regulation of reactive oxygen species and the role of mitochondrial apoptotic‐related genes in rheumatoid arthritis
10.1038/s41598-025-85460-x · 2025 · External reference
Aberrant reactive oxygen and nitrogen species generation in rheumatoid arthritis (RA): causes and consequences for immune function, cell survival, and therapeutic intervention
10.1089/ars.2009.2607 · 2010 · External reference
Base excision repair of oxidative DNA damage: from mechanism to disease
10.2741/4555 · 2017 · External reference
Mammalian DNA base excision repair: dancing in the moonlight
10.1016/j.dnarep.2020.102921 · 2020 · External reference
How are base excision DNA repair pathways deployed in vivo?
10.12688/f1000research.10538.1 · 2017 · External reference
Base excision repair in the immune system: small DNA lesions with big consequences
10.3389/fimmu.2020.01084 · 2020 · External reference
Eukaryotic Base excision repair: new approaches Shine light on mechanism
10.1146/annurev-biochem-013118-111315 · 2019 · External reference
Protein–protein interactions in base excision repair
10.3390/biom15060890 · 2025 · External reference
Base excision DNA repair deficient cells: from disease models to genotoxicity sensors
10.2174/1381612825666190319112930 · 2019 · External reference
Base excision repair: mechanisms and impact in biology, disease, and medicine
10.3390/ijms241814186 · 2023 · External reference
Modulation of immune response to induced‐arthritis by low‐level laser therapy
10.1002/jbio.201800120 · 2019 · External reference
Oxidative stress: harms and benefits for human health
10.1155/2017/8416763 · 2017 · External reference
The impact of base excision DNA repair in age‐related neurodegenerative diseases
2015 · External reference
Mechanisms of human DNA repair: an update
10.1016/s0300-483x(03)00287-7 · 2003 · External reference
Early steps in the DNA base excision/single‐strand interruption repair pathway in mammalian cells
10.1038/cr.2008.8 · 2008 · External reference
Base excision repair and cancer
10.1016/j.canlet.2011.12.038 · 2012 · External reference
Transcription coupled base excision repair in mammalian cells: so little is known and so much to uncover
10.1016/j.dnarep.2021.103204 · 2021 · External reference
Base excision repair in the mitochondria
10.1002/jcb.25103 · 2015 · External reference
Reactive oxygen species regulate both priming and established arthritis, but with different mechanisms
10.1089/ars.2016.6981 · 2017 · External reference
Reactive oxygen species production by monocytes negatively correlates with disease activity in rheumatoid arthritis
10.1016/j.imlet.2025.107052 · 2025 · External reference
The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA
10.1016/s0921-8777(01)00063-5 · 2001 · External reference
DNA repair endonucleases: physiological roles and potential as drug targets
10.1177/1087057115581581 · 2015 · External reference
The association between inefficient repair of oxidative DNA lesions and common polymorphisms of the key base excision repair genes as well as their expression levels in patients with rheumatoid arthritis
2025 · External reference
Polymorphisms in DNA repair genes and association with rheumatoid arthritis in a pilot study on a central European population
10.3390/ijms24043804 · 2023 · External reference
Possible association of the X‐ray cross complementing gene 1 (XRCC1) Arg280His polymorphism as a risk for rheumatoid arthritis
10.1007/s00296-005-0066-3 · 2006 · External reference
Polymorphisms in DNA repair genes XRCC1 and OGG1 lead to the progression of rheumatoid arthritis in Pakistani patients
2016 · External reference
Expression of DNA repair genes in burned skin exposed to low‐level red laser
10.1007/s10103-014-1612-6 · 2014 · External reference
Low‐power laser alters mRNA levels from DNA repair genes in acute lung injury induced by sepsis in Wistar rats
10.1007/s10103-018-2656-9 · 2019 · External reference
Effects of low‐power red laser and blue LED on mRNA levels from DNA repair genes in human breast cancer cells
10.1007/s10103-024-04001-6 · 2024 · External reference
Effect of laser therapy on DNA damage
10.1002/lsm.20921 · 2010 · External reference
Infrared laser effects at fluences used for treatment of dentin hypersensitivity on DNA repair in Escherichia coli and plasmids
10.1016/j.optlastec.2014.04.023 · 2014 · External reference
Low intensity infrared laser affects expression of oxidative DNA repair genes in mitochondria and nucleus
10.1088/1054-660x/24/11/115605 · 2014 · External reference
Low‐power infrared laser modulates mRNA levels from genes of base excision repair and genomic stabilization in heart tissue from an experimental model of acute lung injury
10.1007/s43630-022-00221-3 · 2022 · External reference
Low intensity infrared laser induces filamentation in Escherichia coli cells
10.1134/s1054660x11170051 · 2011 · External reference
DNA repair gene expression in biological tissues exposed to low‐intensity infrared laser
10.1007/s10103-012-1191-3 · 2013 · External reference
Rheumatoid arthritis risk associates with DNA repair gene XRCC1 Arg399Gln polymorphism in Turkish patients
10.1007/s00296-010-1725-6 · 2012 · External reference
Association of XRCC1 and OGG1 DNA repair gene polymorphisms with rheumatoid arthritis in Egyptian patients
10.1016/j.gene.2015.12.021 · 2016 · External reference
Meta‐analysis of associations between XRCC1 gene polymorphisms and susceptibility to systemic lupus erythematosus and rheumatoid arthritis
10.1111/1756-185x.12966 · 2018 · External reference
A novel mechanism for macrophage pyroptosis in rheumatoid arthritis induced by pol β deficiency
10.1038/s41419-022-05047-6 · 2022 · External reference
Increased sensitivity of PBMCs isolated from patients with rheumatoid arthritis to DNA damaging agents is connected with inefficient DNA repair
10.3390/jcm9040988 · 2020 · External reference
Fen1 mutations result in autoimmunity, chronic inflammation and cancers
10.1038/nm1599 · 2007 · External reference
Over‐expression and hypomethylation of flap endonuclease 1 gene in breast and other cancers
10.1158/1541-7786.mcr-08-0269 · 2008 · External reference
Association between the genetic variants of base excision repair pathway genes and allergic rhinitis susceptibility in Chinese children
10.1016/j.waojou.2022.100650 · 2022 · External reference
Biomimetic siRNA therapeutics attenuate mitochondrial DNA damage and cytokine storm in sepsis
10.1016/j.jconrel.2025.114545 · 2026 · External reference
Chronic perfluorobutanoic acid (PFBA) exposure induces apoptosis and inflammation of gill in zebrafish (Danio rerio)
10.1016/j.fsi.2026.111164 · 2026 · External reference
DNA damage induced by T‐2 mycotoxin in human skin fibroblast cell line‐Hs68
10.3390/ijms241914458 · 2023 · External reference
Association between single‐nucleotide polymorphisms of the hOGG1, NEIL1, APEX1, FEN1, LIG1, and LIG3 genes and Alzheimer's disease risk
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