Research graph
References from Agomelatine ameliorates abortion‐related alterations in rats: Insights from behavioural, biochemical and histological analyses. Local targets link to admitted publications; unresolved targets remain external evidence.
Forced swimming‐induced depressive‐like behavior and anxiety are reduced by Chlorpheniramine via suppression of oxidative and inflammatory mediators and activating the Nrf2‐BDNF signaling pathway
10.3390/cimb45080407 · 2023 · External reference
Bed rest during pregnancy for preventing miscarriage
2005 · External reference
Effect of vitamin D3 on depressive behaviors of rats exposed to chronic unpredictable mild stress
10.3390/biomedicines11082112 · 2023 · External reference
Cardioprotective effects of melatonin and metformin against doxorubicin‐induced cardiotoxicity in rats are through preserving mitochondrial function and dynamics
10.1016/j.bcp.2021.114743 · 2021 · External reference
Progesterone‐regulated endometrial factors controlling implantation
10.1111/aji.12473 · 2016 · External reference
Antidepressant‐like activity of S 20098 (agomelatine) in the forced swimming test in rodents: Involvement of melatonin and serotonin receptors
10.1139/jpn.0414 · 2004 · External reference
The human placenta: New perspectives on its formation and function during early pregnancy
10.1098/rspb.2023.0191 · 2023 · External reference
Progesterone‐mediated reversal of mifepristone‐induced pregnancy termination in a rat model: An exploratory investigation
10.1038/s41598-023-38025-9 · 2023 · External reference
Studies on the reproductive effects of chronic treatment with agomelatine in the rat
10.1016/j.ejphar.2015.11.054 · 2016 · External reference
Melatonin Promotes Uterine and Placental Health: Potential Molecular Mechanisms
10.3390/ijms21010300 · 2020 · External reference
The endocrine function of human placenta: An overview
10.1016/j.rbmo.2015.10.005 · 2016 · External reference
Melatonin‐MT1 signal is essential for endometrial decidualization
10.1530/rep-21-0159 · 2021 · External reference
Unresolved reference
2022 · External reference
The prevent miscarriage effects of Yun Kang oral liquid on threatened abortion rat induced by kidney deficiency and luteum inhibition
2019 · External reference
90 YEARS OF PROGESTERONE: New insights into progesterone receptor signaling in the endometrium required for embryo implantation
10.1530/jme-19-0212 · 2020 · External reference
Effect of vitamin D and location of asprosin, spexin and meteorin‐like antibodies in the liver of rats with isoproterenol‐induced myocardial infarction
10.1007/s00210-025-04409-z · 2025 · External reference
Biosynthesis and catabolism of prostaglandin F2(alpha) (PGF2α) are controlled by progesterone in the rat uterus during pregnancy
10.1016/j.jsbmb.2004.05.001 · 2004 · External reference
A systematic, updated review on the antidepressant agomelatine focusing on its melatonergic modulation
10.2174/157015910792246227 · 2010 · External reference
Pharmacovigilance study of the association between progestogen and depression based on the FDA adverse event reporting System (FAERS)
10.1038/s41598-025-85826-1 · 2025 · External reference
Melissa officinalis L. hydro‐alcoholic extract inhibits anxiety and depression through prevention of central oxidative stress and apoptosis
10.1113/ep088254 · 2020 · External reference
Progesterone receptor in the vascular endothelium triggers physiological uterine permeability preimplantation
10.1016/j.cell.2013.12.025 · 2014 · External reference
Pregnancy‐induced adaptation in the neuroendocrine control of prolactin secretion
10.1111/j.1365-2826.2008.01661.x · 2008 · External reference
The mental health impact of perinatal loss: A systematic review and meta‐analysis
10.1016/j.jad.2021.10.026 · 2022 · External reference
Rola błonowych receptorów melatoniny w zależnym od melatoniny uwalnianiu oksytocyny z układu podwzgórze‐część nerwowa przysadki szczura—Badania in vitro oraz in vivo
10.5603/ep.a2016.0035 · 2016 · External reference
Modulation of melatonin receptors regulates reproductive physiology: The impact of agomelatine on the estrus cycle, gestation, offspring, and uterine contractions in rats
10.33549/physiolres.935064 · 2023 · External reference
Agomelatine in the treatment of major depressive disorder: Potential for clinical effectiveness
2010 · External reference
Agomelatine inhibits spontaneous and prostaglandin F2 alpha induced contractions of rat myometrium through mechanisms interacting both extracellular and intracellular calcium signaling
2015 · External reference
Agomelatine (S20098) modulates the expression of cytoskeletal microtubular proteins, synaptic markers and BDNF in the rat hippocampus, amygdala and PFC
10.1007/s00213-011-2597-5 · 2012 · External reference
Melatonin: The watchdog of villous trophoblast homeostasis against hypoxia/reoxygenation‐induced oxidative stress and apoptosis
10.1016/j.mce.2013.07.010 · 2013 · External reference
PGE2 vs PGF2α in human parturition
10.1016/j.placenta.2020.12.012 · 2021 · External reference
Aberrant expression of oxytocin receptor in endometrium and decidua in women who have experienced recurrent implantation failure
10.1016/j.xfss.2020.10.004 · 2020 · External reference
Patterns of sex hormone receptor expression in stimulated endometrium from oocyte donors
10.1080/14647273.2021.1871783 · 2022 · External reference
Determination of the estrous cycle phases of rats: Some helpful considerations
10.1590/s1519-69842002000400008 · 2002 · External reference
The novel melatonin agonist agomelatine (S20098) is an antagonist at 5‐Hydroxytryptamine2C receptors, blockade of which enhances the activity of frontocortical dopaminergic and adrenergic pathways
10.1124/jpet.103.051797 · 2003 · External reference
Inflammatory responses in early pregnancy: Physiological and pathological perspectives
10.1002/rmb2.12619 · 2024 · External reference
Implantation and the survival of early pregnancy
10.1056/nejmra000763 · 2001 · External reference
The association between psychological stress and miscarriage: A systematic review and meta‐analysis
10.1038/s41598-017-01792-3 · 2017 · External reference
Miscarriage matters: The epidemiological, physical, psychological, and economic costs of early pregnancy loss
10.1016/s0140-6736(21)00682-6 · 2021 · External reference
Behavioral and electrophysiological (ECoG) effects of haplophyllum robustum and TRPA1 antagonist in adult male wistar rats
10.1016/j.toxicon.2023.107233 · 2023 · External reference
Melatonin receptor 1B and corticosteroid receptor polymorphisms in infertile women with implantation failure and miscarriages
10.31083/j.fbl2806122 · 2023 · External reference
Impact of first trimester and postpartum period thyroid autoantibodies on abortus incidence in Turkish pregnant women
10.1080/09513590902730812 · 2009 · External reference
Threatened miscarriage: Evaluation and management
2004 · External reference
Agomelatine in depressive disorders: Its novel mechanisms of action
10.1176/appi.neuropsych.11090216 · 2012 · External reference
Agomelatine: A potential novel approach for the treatment of memory disorder in neurodegenerative disease
10.4103/1673-5374.353479 · 2023 · External reference
Importance of melatonin in assisted reproductive technology and ovarian aging
10.3390/ijms21031135 · 2020 · External reference
Melatonin and pregnancy in the human
10.1016/j.reprotox.2008.03.005 · 2008 · External reference
Decidualization and related pregnancy complications
10.1097/fm9.0000000000000135 · 2022 · External reference
The role of melatonin in pregnancy and the health benefits for the newborn
10.3390/biomedicines10123252 · 2022 · External reference
Single administration of ultra‐low‐dose lipopolysaccharide in rat early pregnancy induces tlr4 activation in the placenta contributing to preeclampsia
10.1371/journal.pone.0124001 · 2015 · External reference
Dynamic function and composition changes of immune cells during normal and pathological pregnancy at the maternal‐fetal interface
10.3389/fimmu.2019.02317 · 2019 · External reference
Effects of melatonin administration on embryo implantation and offspring growth in mice under different schedules of photoperiodic exposure
10.1186/s12958-017-0297-7 · 2017 · External reference
Study on prevention effect of Zishen Yutai pill combined with progesterone for threatened abortion in rats
10.1016/j.apjtm.2016.04.002 · 2016 · External reference
Melatonin alleviates lipopolysaccharide‐induced abnormal pregnancy through MTNR1B regulation of m6A
10.3390/ijms25020733 · 2024 · External reference