Research graph
References from FAK inhibitor and RAF/MEK clamp avutometinib enhance KRAS G12C inhibitor efficacy in preclinical models of non–small cell lung cancer. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1056/nejmc2030638
10.1056/nejmc2030638 · External reference
10.3322/caac.21654
10.3322/caac.21654 · External reference
10.3390/genes12060899
10.3390/genes12060899 · External reference
10.1080/14796694.2024.2407280
10.1080/14796694.2024.2407280 · External reference
10.1056/nejmoa2103695
10.1056/nejmoa2103695 · External reference
10.1056/nejmoa2204619
10.1056/nejmoa2204619 · External reference
10.1016/s0140-6736(23)00221-0
10.1016/s0140-6736(23)00221-0 · External reference
10.1200/jco.2024.42.17_suppl.lba8509
10.1200/jco.2024.42.17_suppl.lba8509 · External reference
10.1056/nejmoa2303810
10.1056/nejmoa2303810 · External reference
10.1200/jco.2024.42.16_suppl.3007
10.1200/jco.2024.42.16_suppl.3007 · External reference
10.1158/1535-7163.targ-23-pr014
10.1158/1535-7163.targ-23-pr014 · External reference
10.1158/1078-0432.ccr-18-0368
10.1158/1078-0432.ccr-18-0368 · External reference
10.1158/1078-0432.ccr-20-2077
10.1158/1078-0432.ccr-20-2077 · External reference
10.1038/s41586-021-04065-2
10.1038/s41586-021-04065-2 · External reference
10.1158/2159-8290.cd-21-0365
10.1158/2159-8290.cd-21-0365 · External reference
10.1056/nejmoa2105281
10.1056/nejmoa2105281 · External reference
10.1158/2159-8290.cd-24-0421
10.1158/2159-8290.cd-24-0421 · External reference
10.1038/s41467-024-51828-2
10.1038/s41467-024-51828-2 · External reference
10.1158/1078-0432.ccr-19-3523
10.1158/1078-0432.ccr-19-3523 · External reference
10.1002/advs.202100250
10.1002/advs.202100250 · External reference
10.1186/s40164-023-00446-7
10.1186/s40164-023-00446-7 · External reference
10.1016/s0002-9440(10)63370-6
10.1016/s0002-9440(10)63370-6 · External reference
10.1016/j.canlet.2009.07.005
10.1016/j.canlet.2009.07.005 · External reference
10.1158/0008-5472.can-12-3937
10.1158/0008-5472.can-12-3937 · External reference
10.1016/j.ccr.2014.03.011
10.1016/j.ccr.2014.03.011 · External reference
10.20892/j.issn.2095-3941.2019.0137
10.20892/j.issn.2095-3941.2019.0137 · External reference
10.1016/s1470-2045(20)30464-2
10.1016/s1470-2045(20)30464-2 · External reference
10.1016/j.ccell.2025.02.001
10.1016/j.ccell.2025.02.001 · External reference
10.1038/s41591-025-03763-y
10.1038/s41591-025-03763-y · External reference
Efficacy and safety of avutometinib ± defactinib in recurrent low-grade serous ovarian cancer: Primary analysis of ENGOT-OV60/GOG-3052/RAMP 201
2025 · External reference
10.1016/j.ccell.2024.02.012
10.1016/j.ccell.2024.02.012 · External reference
10.1038/s41568-024-00679-6
10.1038/s41568-024-00679-6 · External reference
10.1158/1538-7445.am2022-nd11
10.1158/1538-7445.am2022-nd11 · External reference
10.1158/1538-7445.am2021-1259
10.1158/1538-7445.am2021-1259 · External reference
10.1021/acs.jmedchem.4c02313
10.1021/acs.jmedchem.4c02313 · External reference
10.1158/2159-8290.cd-24-0027
10.1158/2159-8290.cd-24-0027 · External reference
10.1126/scitranslmed.3008639
10.1126/scitranslmed.3008639 · External reference
10.1016/j.cels.2015.12.004
10.1016/j.cels.2015.12.004 · External reference
10.1172/jci164413
10.1172/jci164413 · External reference
10.1158/2159-8290.cd-25-0349
10.1158/2159-8290.cd-25-0349 · External reference
10.1158/1535-7163.targ-21-p05-01
10.1158/1535-7163.targ-21-p05-01 · External reference
10.1158/1535-7163.targ-21-p05-02
10.1158/1535-7163.targ-21-p05-02 · External reference
10.1200/jco.2024.42.16_suppl.8605
10.1200/jco.2024.42.16_suppl.8605 · External reference
10.1038/s41586-024-07205-6
10.1038/s41586-024-07205-6 · External reference
10.1158/2326-6074.io2025-pr012
10.1158/2326-6074.io2025-pr012 · External reference
10.1158/2159-8290.cd-21-1331
10.1158/2159-8290.cd-21-1331 · External reference
10.1016/j.gpb.2022.01.004
10.1016/j.gpb.2022.01.004 · External reference
Generation of primary tumors with Flp recombinase in FRT-flanked p53 mice
2012 · External reference
10.1016/j.cell.2017.12.020
10.1016/j.cell.2017.12.020 · External reference
10.1038/emboj.2010.7
10.1038/emboj.2010.7 · External reference
10.1093/bioinformatics/bts236
10.1093/bioinformatics/bts236 · External reference
Unresolved reference
External reference
10.1093/bioinformatics/bts635
10.1093/bioinformatics/bts635 · External reference
Unresolved reference
External reference
10.1093/gigascience/giab008
10.1093/gigascience/giab008 · External reference
10.1126/science.adk0775
10.1126/science.adk0775 · External reference
