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References from Propionate promotes CD8 + T-cell infiltration and enhances immunotherapy efficacy in colorectal cancer. Local targets link to admitted publications; unresolved targets remain external evidence.
Survival improvement for patients with metastatic colorectal cancer over twenty years
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Cancer treatment and survivorship statistics, 2025
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The impact of gut microbial short-chain fatty acids on colorectal cancer development and prevention
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The immune microenvironment of colorectal cancer
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The Prevalence and Prognosis of Microsatellite Instability-High/Mismatch Repair-Deficient Colorectal Adenocarcinomas in the United States
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Effectiveness and Safety of Immune Checkpoint Inhibitors in Colorectal Cancer: A Systematic Review of Real-World Studies
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Microbial metabolites for cancer immunotherapy: Current evidence and future directions
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Role of Crosstalk Between Gut Microbiota and Immune Cells in Colorectal Cancer: A Narrative Review
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Microbial metabolite butyrate promotes anti-PD-1 antitumor efficacy by modulating T cell receptor signaling of cytotoxic CD8 T cell
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10.1016/j.cell.2024.02.022
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Research progress on gut microbiota in colorectal cancer immunotherapy
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Short-chain fatty acids in the tumor microenvironment: from molecular mechanisms to cancer therapy
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Short-chain fatty acids and cancer
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The role of key gut microbial metabolites in the development and treatment of cancer
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The emerging role of dysregulated propionate metabolism and methylmalonic acid in metabolic disease, aging, and cancer
10.1016/j.cmet.2025.01.005 · 2025 · External reference
Microbiome as a biomarker and therapeutic target in pancreatic cancer
10.1186/s12866-023-03166-4 · 2024 · External reference
Gut microbiota and SCFAs improve the treatment efficacy of chemotherapy and immunotherapy in NSCLC
10.1038/s41522-025-00785-9 · 2025 · External reference
Metabolic interactions: how gut microbial metabolites influence colorectal cancer
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Short chain fatty acids prime colorectal cancer cells to activate antitumor immunity
10.3389/fimmu.2023.1190810 · 2023 · External reference
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Galectin-7 Induction by EHMT2 Inhibition Enhances Immunity in Microsatellite Stability Colorectal Cancer
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