Research graph
References from GTPase RAB31 supports ANXA1-driven macrophage education through clathrin-mediated endocytosis to suppress antitumor immunity. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1038/s41568-022-00547-1
10.1038/s41568-022-00547-1 · External reference
10.1016/j.ccell.2024.04.002
10.1016/j.ccell.2024.04.002 · External reference
Decoding the spatiotemporal heterogeneity of tumor-associated macrophages
10.1186/s12943-024-02064-1 · 2024 · External reference
10.1158/2159-8290.cd-23-1300
10.1158/2159-8290.cd-23-1300 · External reference
10.1111/j.1582-4934.2009.00926.x
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10.1158/2159-8290.cd-14-0621
10.1158/2159-8290.cd-14-0621 · External reference
10.1056/nejmoa1411366
10.1056/nejmoa1411366 · External reference
10.1158/1078-0432.ccr-13-0525
10.1158/1078-0432.ccr-13-0525 · External reference
Radiation Therapy-Induced Tumor Invasiveness Is Associated with SDF-1-Regulated Macrophage Mobilization and Vasculogenesis
10.1371/journal.pone.0069182 · 2013 · External reference
10.1182/blood-2009-12-258186
10.1182/blood-2009-12-258186 · External reference
10.1016/j.immuni.2017.07.014
10.1016/j.immuni.2017.07.014 · External reference
10.1073/pnas.1121623109
10.1073/pnas.1121623109 · External reference
10.1126/science.1238856
10.1126/science.1238856 · External reference
10.1038/nature19834
10.1038/nature19834 · External reference
10.1158/2159-8290.cd-15-1032
10.1158/2159-8290.cd-15-1032 · External reference
The essential clathrin adapter protein complex-2 is tumor suppressive specifically in vivo
10.1038/s41467-025-57521-2 · 2025 · External reference
mTOR Repression in Response to Amino Acid Starvation Promotes ECM Degradation Through MT1-MMP Endocytosis Arrest
10.1002/advs.202101614 · 2021 · External reference
10.1126/science.274.5295.2086
10.1126/science.274.5295.2086 · External reference
10.1038/ncb1252
10.1038/ncb1252 · External reference
10.1016/s0962-8924(01)02082-7
10.1016/s0962-8924(01)02082-7 · External reference
Piezo1 activates noncanonical EGFR endocytosis and signaling
10.1126/sciadv.adi1328 · 2023 · External reference
10.1038/s41467-020-14809-9
10.1038/s41467-020-14809-9 · External reference
Cell Permeating Nano-Complexes of Amphiphilic Polyelectrolytes Enhance Solubility, Stability, and Anti-Cancer Efficacy of Curcumin
10.1021/acs.biomac.6b00417 · 2016 · External reference
10.1021/acsnano.7b00275
10.1021/acsnano.7b00275 · External reference
10.1038/nrm1500
10.1038/nrm1500 · External reference
10.1016/j.cell.2024.08.017
10.1016/j.cell.2024.08.017 · External reference
10.1182/bloodadvances.2019031286
10.1182/bloodadvances.2019031286 · External reference
10.1093/neuonc/nox104
10.1093/neuonc/nox104 · External reference
10.1016/j.ccr.2014.04.030
10.1016/j.ccr.2014.04.030 · External reference
10.1182/blood-2007-01-066027
10.1182/blood-2007-01-066027 · External reference
Characterization of Rab32- and Rab38-positive lysosome-related organelles in osteoclasts and macrophages
10.1016/j.jbc.2023.105191 · 2023 · External reference
IL-33/NF-κB/ST2L/Rab37 positive-feedback loop promotes M2 macrophage to limit chemotherapeutic efficacy in lung cancer
10.1038/s41419-024-06746-y · 2024 · External reference
Correction to: Prioritizing risk genes as novel stratification biomarkers for acute monocytic leukemia by integrative analysis
10.1007/s12672-022-00526-w · 2022 · External reference
10.1016/j.celrep.2025.115631
10.1016/j.celrep.2025.115631 · External reference
Single-cell and spatial transcriptomics reveal the pathogenesis of chronic granulomatous disease in a natural model
10.1016/j.celrep.2025.115612 · 2025 · External reference
Rab31 expression levels modulate tumor-relevant characteristics of breast cancer cells
10.1186/1476-4598-11-62 · 2012 · External reference
Increased RAB31 Expression in Cancer-Associated Fibroblasts Promotes Colon Cancer Progression Through HGF-MET Signaling
10.3389/fonc.2020.01747 · 2020 · External reference
Non-coding RNA RMRP governs RAB31-dependent MMP secretion, enhancing ovarian cancer invasion
10.1016/j.bbadis.2025.167781 · 2025 · External reference
Rab31-dependent regulation of transforming growth factor ß expression in breast cancer cells
10.1186/s10020-021-00419-8 · 2021 · External reference
Rab31 promotes the invasion and metastasis of cervical cancer cells by inhibiting MAPK6 degradation
10.7150/ijbs.63388 · 2022 · External reference
10.3389/fimmu.2020.580302
10.3389/fimmu.2020.580302 · External reference
10.1126/science.291.5506.1051
10.1126/science.291.5506.1051 · External reference
10.1038/nrm3266
10.1038/nrm3266 · External reference
10.1172/jci65289
10.1172/jci65289 · External reference
10.1016/j.cell.2011.10.038
10.1016/j.cell.2011.10.038 · External reference
Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force
10.1038/ncomms9672 · 2015 · External reference
Patterns of human and porcine gammaherpesvirus-encoded BILF1 receptor endocytosis
10.1186/s11658-023-00427-y · 2023 · External reference
10.1016/j.kint.2021.02.025
10.1016/j.kint.2021.02.025 · External reference
Unresolved reference
External reference
10.1016/bs.ircmb.2018.03.002
10.1016/bs.ircmb.2018.03.002 · External reference
10.1016/s0031-6997(24)01478-9
10.1016/s0031-6997(24)01478-9 · External reference
10.1016/j.tips.2017.04.002
10.1016/j.tips.2017.04.002 · External reference
10.1126/science.1109237
10.1126/science.1109237 · External reference
Annexin A1 (Ac2-26)-dependent Fpr2 receptor alleviates sepsis-induced acute kidney injury by inhibiting inflammation and apoptosis in vivo and in vitro
10.1007/s00011-022-01640-9 · 2023 · External reference
25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages
10.1016/j.immuni.2024.03.021 · 2024 · External reference
Rab31 promotes metastasis and cisplatin resistance in stomach adenocarcinoma through Twist1-mediated EMT
10.1038/s41419-023-05596-4 · 2023 · External reference
Baohuoside I chemosensitises breast cancer to paclitaxel by suppressing extracellular vesicle/CXCL1 signal released from apoptotic cells
10.1002/jev2.12493 · 2024 · External reference
Transcriptional coregualtor NUPR1 maintains tamoxifen resistance in breast cancer cells
10.1038/s41419-021-03442-z · 2021 · External reference
10.1038/nature21409
10.1038/nature21409 · External reference
The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport
10.1016/j.immuni.2018.04.011 · 2018 · External reference
Loss of Annexin A1 in macrophages restrains efferocytosis and remodels immune microenvironment in pancreatic cancer by activating the cGAS/STING pathway
10.1136/jitc-2024-009318 · 2024 · External reference
FPR2 Shapes an Immune-Excluded Pancreatic Tumor Microenvironment and Drives T-cell Exhaustion in a Sex-Dependent Manner
10.1158/0008-5472.can-22-2932 · 2023 · External reference
Deciphering tumor microenvironment: CXCL9 and SPP1 as crucial determinants of tumor-associated macrophage polarity and prognostic indicators
10.1186/s12943-023-01931-7 · 2024 · External reference
10.1158/0008-5472.can-17-0428
10.1158/0008-5472.can-17-0428 · External reference
Unresolved reference
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Single-cell analysis reveals new evolutionary complexity in uveal melanoma
10.1038/s41467-019-14256-1 · 2020 · External reference
Unresolved reference
External reference
10.1158/1078-0432.ccr-19-3231
10.1158/1078-0432.ccr-19-3231 · External reference
10.1016/j.ccell.2021.09.010
10.1016/j.ccell.2021.09.010 · External reference
