Research graph
References from High-Risk Rhabdomyosarcomas Feature a Convergent Cell State. Local targets link to admitted publications; unresolved targets remain external evidence.
Prognostic factors in metastatic rhabdomyosarcomas: results of a pooled analysis from United States and European cooperative groups
10.1200/jco.2007.14.7207 · 2008 · External reference
Prognostic factors after relapse in nonmetastatic rhabdomyosarcoma: a nomogram to better define patients who can be salvaged with further therapy
10.1200/jco.2010.32.1984 · 2011 · External reference
The impact of age on outcome of embryonal and alveolar rhabdomyosarcoma patients. A multicenter study
2012 · External reference
AKT and PAX3-FKHR cooperation enforces myogenic differentiation blockade in alveolar rhabdomyosarcoma cell
10.4161/cc.11.5.19346 · 2012 · External reference
Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma
10.1038/ng1193-230 · 1993 · External reference
Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors
10.1158/2159-8290.cd-13-0639 · 2014 · External reference
Alveolar rhabdomyosarcoma: a prognostically unfavorable rhabdomyosarcoma type and its necessary distinction from embryonal rhabdomyosarcoma
10.1007/978-3-642-77289-4_14 · 1995 · External reference
Rhabdomyosarcoma in children and young adults
10.1007/s00428-024-03961-y · 2025 · External reference
Pathologic classification of rhabdomyosarcomas and correlations with molecular studies
10.1038/modpathol.3880339 · 2001 · External reference
The myogenesis program drives clonal selection and drug resistance in rhabdomyosarcoma
10.1016/j.devcel.2022.04.003 · 2022 · External reference
Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma
10.1038/s43018-022-00414-w · 2022 · External reference
Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance
10.1126/sciadv.ade9238 · 2023 · External reference
Single-cell transcriptomics reveals immune suppression and cell states predictive of patient outcomes in rhabdomyosarcoma
10.1038/s41467-023-38886-8 · 2023 · External reference
Single cell transcriptomic profiling identifies tumor-acquired and therapy-resistant cell states in pediatric rhabdomyosarcoma
10.1038/s41467-024-50527-2 · 2024 · External reference
Recurrent MYOD1 mutations in pediatric and adult sclerosing and spindle cell rhabdomyosarcomas: evidence for a common pathogenesis
10.1002/gcc.22187 · 2014 · External reference
SCANPY: large-scale single-cell gene expression data analysis
10.1186/s13059-017-1382-0 · 2018 · External reference
Scrublet: computational identification of cell doublets in single-cell transcriptomic data
10.1016/j.cels.2018.11.005 · 2019 · External reference
A fast, scalable and versatile tool for analysis of single-cell omics data
10.1038/s41592-023-02139-9 · 2024 · External reference
Model-based analysis of ChIP-Seq (MACS)
10.1186/gb-2008-9-9-r137 · 2008 · External reference
ChromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data
10.1038/nmeth.4401 · 2017 · External reference
JASPAR 2020: update of the open-access database of transcription factor binding profiles
10.1093/nar/gkz1001 · 2020 · External reference
COSMIC: somatic cancer genetics at high-resolution
10.1093/nar/gkw1121 · 2017 · External reference
GRIDSS: sensitive and specific genomic rearrangement detection using positional de Bruijn graph assembly
10.1101/gr.222109.117 · 2017 · External reference
STAR: ultrafast universal RNA-seq aligner
10.1093/bioinformatics/bts635 · 2013 · External reference
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
10.1093/bioinformatics/btp616 · 2010 · External reference
Single sample scoring of molecular phenotypes
10.1186/s12859-018-2435-4 · 2018 · External reference
A human embryonic limb cell atlas resolved in space and time
10.1038/s41586-023-06806-x · 2024 · External reference
Blood and immune development in human fetal bone marrow and Down syndrome
10.1038/s41586-021-03929-x · 2021 · External reference
Single-cell transcriptomics identifies chondrocyte differentiation dynamics in vivo and in vitro
10.1016/j.devcel.2025.06.031 · 2025 · External reference
Identification of therapeutic targets in rhabdomyosarcoma through integrated genomic, epigenomic, and proteomic analyses
10.1016/j.ccell.2018.07.012 · 2018 · External reference
Mesenchymal tumor organoid models recapitulate rhabdomyosarcoma subtypes
10.15252/emmm.202216001 · 2022 · External reference
Proteomics. Tissue-based map of the human proteome
10.1126/science.1260419 · 2015 · External reference
clusterProfiler: an R package for comparing biological themes among gene clusters
10.1089/omi.2011.0118 · 2012 · External reference
A third-generation lentivirus vector with a conditional packaging system
10.1128/jvi.72.11.8463-8471.1998 · 1998 · External reference
An integrated TCGA pan-cancer clinical data resource to drive high-quality survival outcome analytics
10.1016/j.cell.2018.02.052 · 2018 · External reference
Squidpy: a scalable framework for spatial omics analysis
10.1038/s41592-021-01358-2 · 2022 · External reference
The GTEx Consortium atlas of genetic regulatory effects across human tissues
10.1126/science.aaz1776 · 2020 · External reference
CellPhoneDB v5: inferring cell–cell communication from single-cell multiomics data
10.1038/s41596-024-01137-1 · 2025 · External reference
Characterization of an anti-fetal AChR monoclonal antibody isolated from a myasthenia gravis patient
10.1038/s41598-017-14350-8 · 2017 · External reference
Revealing the BRD4-NOTCH3 fusion: a novel hill in the cancer landscape
10.1016/j.lungcan.2021.02.016 · 2021 · External reference
Precise identification of cancer cells from allelic imbalances in single cell transcriptomes
10.1038/s42003-022-03808-9 · 2022 · External reference
Salient features of mesenchymal stem cells-implications for Ewing sarcoma modeling
10.3389/fonc.2013.00024 · 2013 · External reference
Fusion gene-negative alveolar rhabdomyosarcoma is clinically and molecularly indistinguishable from embryonal rhabdomyosarcoma
10.1200/jco.2009.26.3814 · 2010 · External reference
Identification of a PAX-FKHR gene expression signature that defines molecular classes and determines the prognosis of alveolar rhabdomyosarcomas
10.1158/0008-5472.can-05-4578 · 2006 · External reference
HOX gene expression in the developing human spine
10.1038/s41467-024-54187-0 · 2024 · External reference
Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell
10.1126/sciadv.abd3311 · 2021 · External reference
Immunotherapeutic targeting of GPC3 in pediatric solid embryonal tumors
10.3389/fonc.2019.00108 · 2019 · External reference
CAR T-cells targeting FGFR4 and CD276 simultaneously show potent antitumor effect against childhood rhabdomyosarcoma
10.1038/s41467-024-50251-x · 2024 · External reference
Rhabdomyosarcoma fusion oncoprotein initially pioneers a neural signature in vivo
10.1016/j.celrep.2025.115923 · 2025 · External reference
Relapsed rhabdomyosarcoma
10.3390/jcm10040804 · 2021 · External reference
ZFP64::NCOA3 gene fusion defines a novel subset of spindle cell rhabdomyosarcoma
10.1002/gcc.23052 · 2022 · External reference
Novel fusion genes in spindle cell rhabdomyosarcoma: the spectrum broadens
10.1002/gcc.22978 · 2021 · External reference
A convergent cell state of high-risk rhabdomyosarcoma
10.5281/zenodo.16785315 · 2025 · External reference
