Research graph
References from HPV16 Genomic Status Stratifies Risk of Disease Recurrence in Oropharyngeal Squamous Cell Carcinoma. Local targets link to admitted publications; unresolved targets remain external evidence.
Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial
10.1093/jnci/djn011 · 2008 · External reference
Human papillomavirus and survival of patients with oropharyngeal cancer
10.1056/nejmoa0912217 · 2010 · External reference
Human papillomavirus-related oropharyngeal cancer
10.1093/annonc/mdx304 · 2017 · External reference
Human papillomavirus and the landscape of secondary genetic alterations in oral cancers
10.1101/gr.241141.118 · 2019 · External reference
Radiotherapy plus cisplatin or cetuximab in low-risk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV): an open-label randomised controlled phase 3 trial
10.1016/s0140-6736(18)32752-1 · 2019 · External reference
Analysis of the integration of human papillomaviruses in head and neck tumours in relation to patients’ prognosis
10.1002/ijc.29712 · 2016 · External reference
Human papillomavirus integration pattern and demographic, clinical, and survival characteristics of patients with oropharyngeal squamous cell carcinoma
10.1002/hed.24429 · 2016 · External reference
Human papilloma virus integration sites and genomic signatures in head and neck squamous cell carcinoma
10.1002/1878-0261.13219 · 2022 · External reference
Characterization of HPV and host genome interactions in primary head and neck cancers
10.1073/pnas.1416074111 · 2014 · External reference
Patients with integrated HPV16 in head and neck cancer show poor survival
10.1016/j.oraloncology.2018.03.015 · 2018 · External reference
HPV integration in HNSCC correlates with survival outcomes, immune response signatures, and candidate drivers
10.1158/1541-7786.mcr-17-0153 · 2018 · External reference
Genetic variation within the human papillomavirus type 16 genome is associated with oropharyngeal cancer prognosis
10.1016/j.annonc.2022.03.005 · 2022 · External reference
Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability
10.1101/gr.164806.113 · 2014 · External reference
Mechanistic signatures of HPV insertions in cervical carcinomas
10.1038/npjgenmed.2016.4 · 2016 · External reference
Whole genome sequencing reveals complexity in both HPV sequences present and HPV integrations in HPV-positive oropharyngeal squamous cell carcinomas
10.1186/s12885-019-5536-1 · 2019 · External reference
Direct comparison of HPV16 viral genomic integration, copy loss, and structural variants in oropharyngeal and uterine cervical cancers reveal distinct relationships to E2 disruption and somatic alteration
10.3390/cancers14184488 · 2022 · External reference
Long-read sequencing unveils high-resolution HPV integration and its oncogenic progression in cervical cancer
10.1038/s41467-022-30190-1 · 2022 · External reference
Rearrangements of viral and human genomes at human papillomavirus integration events and their allele-specific impacts on cancer genome regulation
10.1101/gr.279041.124 · 2025 · External reference
SearcHPV: a novel approach to identify and assemble human papillomavirus-host genomic integration events in cancer
10.1002/cncr.33691 · 2021 · External reference
Direct comparison of alternative blood-based approaches for early detection and diagnosis of HPV-associated head and neck cancers
10.1158/1078-0432.ccr-24-2525 · 2025 · External reference
Episomal HPV16 responsible for aggressive and deadly metastatic anal squamous cell carcinoma evidenced in peripheral blood
10.1038/s41598-021-84110-2 · 2021 · External reference
Digital papillary adenocarcinoma in nonacral skin: clinicopathologic and genetic characterization of 5 cases
10.1097/pas.0000000000002096 · 2023 · External reference
[Advances in screening and follow-up of HPV-related cervical cancer]
10.1684/vir.2026.1125 · 2026 · External reference
Two human papillomavirus 11 complete genomes recovered from inverted sinonasal papillomas in humans
10.1128/mra.01184-23 · 2024 · External reference
Human papilloma virus (HPV) integration signature in Cervical Cancer: identification of MACROD2 gene as HPV hot spot integration site
10.1038/s41416-020-01153-4 · 2021 · External reference
Clonal origin and early lineage divergence in adenosquamous carcinoma
10.1016/j.celrep.2026.117470 · 2026 · External reference
HPV circulating tumoral DNA quantification by droplet-based digital PCR: a promising predictive and prognostic biomarker for HPV-associated oropharyngeal cancers
10.1002/ijc.32804 · 2020 · External reference
Induction nivolumab before chemoradiation in high-risk human papillomavirus–driven oropharynx cancers: IMMUNEBOOST-HPV, a multicenter randomized phase II trial
10.1200/jco-25-00835 · 2026 · External reference
Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): explanation and elaboration
10.1371/journal.pmed.1001216 · 2012 · External reference
Squamous cell carcinoma of the oral cavity, larynx, oropharynx and hypopharynx: EHNS–ESMO–ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up
10.1016/j.annonc.2020.07.011 · 2020 · External reference
Head and neck cancers—major changes in the American Joint Committee on cancer eighth edition cancer staging manual
10.3322/caac.21389 · 2017 · External reference
viroCapt: a bioinformatics pipeline for identifying viral insertion in human host genome
10.3233/shti220602 · 2022 · External reference
[HPV-related oropharyngeal cancers: main characteristics and new virological tools]
10.1684/vir.2026.1124 · 2026 · External reference
New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0
10.1093/sysbio/syq010 · 2010 · External reference
regioneR: an R/Bioconductor package for the association analysis of genomic regions based on permutation tests
10.1093/bioinformatics/btv562 · 2016 · External reference
Intratumor heterogeneity of HPV integration in HPV-associated head and neck cancer
10.1038/s41467-025-56150-z · 2025 · External reference
Diverse tumorigenic consequences of human papillomavirus integration in primary oropharyngeal cancers
10.1101/gr.275911.121 · 2022 · External reference
Intratumoral heterogeneity and clonal evolution induced by HPV integration
10.1158/2159-8290.cd-22-0900 · 2023 · External reference
HPV-associated oropharyngeal cancer: epidemiology, molecular biology and clinical management
10.1038/s41571-022-00603-7 · 2022 · External reference
The combined HPV16-E2/E6/E7 T cell response in oropharyngeal cancer predicts superior survival
10.1016/j.xcrm.2023.101262 · 2023 · External reference