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References from Oncolytic Herpes Virus G47Δ Potentiates ADCC-Inducing Molecular Targeted Therapy via Coordinated Activation of Innate and Adaptive Immune Responses. Local targets link to admitted publications; unresolved targets remain external evidence.
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Immune complex–mediated antigen presentation induces tumor immunity
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Cetuximab-mediated tumor regression depends on innate and adaptive immune responses
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Antigen-antibody immune complexes empower dendritic cells to efficiently prime specific CD8+ CTL responses in vivo
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Trastuzumab increases HER2 uptake and cross-presentation by dendritic cells
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Cetuximab-activated natural killer and dendritic cells collaborate to trigger tumor antigen-specific T-cell immunity in head and neck cancer patients
10.1158/1078-0432.ccr-12-2426 · 2013 · External reference
Oncolytic viruses in cancer treatment: a review
10.1001/jamaoncol.2016.2064 · 2017 · External reference
Oncolytic viruses: a new class of immunotherapy drugs
10.1038/nrd4663 · 2015 · External reference
New generation of oncolytic herpes virus
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Oncolytic virotherapy
10.1038/nbt.2287 · 2012 · External reference
Talimogene laherparepvec improves durable response rate in patients with advanced melanoma
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Oncolytic herpes simplex virus vector with enhanced MHC class I presentation and tumor cell killing
10.1073/pnas.101136398 · 2001 · External reference
Efficacy of a third-generation oncolytic herpes virus G47Δ in advanced stage models of human gastric cancer
10.1016/j.omto.2020.03.022 · 2020 · External reference
Neoadjuvant use of oncolytic herpes virus G47Δ enhances the antitumor efficacy of radiofrequency ablation
10.1016/j.omto.2020.08.010 · 2020 · External reference
Oncolytic herpes virus G47Δ injected into tongue cancer swiftly traffics in lymphatics and suppresses metastasis
10.1016/j.omto.2021.06.008 · 2021 · External reference
Oncolytic herpes virus G47Δ works synergistically with CTLA-4 inhibition through dynamic intratumoral immune modulation
10.1016/j.omto.2021.05.004 · 2021 · External reference
Efficacy and safety of a third-generation oncolytic herpes virus G47Δ in models of human esophageal carcinoma
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Intratumoral oncolytic herpes virus G47Δ for residual or recurrent glioblastoma: a phase 2 trial
10.1038/s41591-022-01897-x · 2022 · External reference
A phase I/II study of triple-mutated oncolytic herpes virus G47Δ in patients with progressive glioblastoma
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In situ expression of soluble B7-1 in the context of oncolytic herpes simplex virus induces potent antitumor immunity
2001 · External reference
Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity
10.1016/j.ccell.2014.09.007 · 2014 · External reference
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Type I interferons in anticancer immunity
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Molecular mechanisms of resistance to cetuximab and panitumumab in colorectal cancer
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Oncolytic virotherapy in cancer treatment: challenges and optimization prospects
10.3389/fimmu.2023.1308890 · 2023 · External reference
The quest to overcome resistance to EGFR-targeted therapies in cancer
10.1038/nm.3388 · 2013 · External reference
Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virus
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Localized oncolytic virotherapy overcomes systemic tumor resistance to immune checkpoint blockade immunotherapy
10.1126/scitranslmed.3008095 · 2014 · External reference
Local delivery of OncoVEXmGM-CSF generates systemic antitumor immune responses enhanced by cytotoxic T-lymphocyte-associated protein blockade
10.1158/1078-0432.ccr-17-0681 · 2017 · External reference
Integrating oncolytic viruses in combination cancer immunotherapy
10.1038/s41577-018-0014-6 · 2018 · External reference
Combination of cetuximab and oncolytic virus canerpaturev synergistically inhibits human colorectal cancer growth
10.1016/j.omto.2019.04.004 · 2019 · External reference
Anti-EGFR targeted monoclonal antibody isotype influences antitumor cellular immunity in head and neck cancer patients
10.1158/1078-0432.ccr-15-2971 · 2016 · External reference
Mouse and human FcR effector functions
10.1111/imr.12350 · 2015 · External reference
NK cell-mediated antibody-dependent cellular cytotoxicity in cancer immunotherapy
10.3389/fimmu.2015.00368 · 2015 · External reference
Oncolytic adenovirus expressing monoclonal antibody trastuzumab for treatment of HER2-positive cancer
10.1158/1535-7163.mct-15-0819 · 2016 · External reference
Oncolytic reovirus enhances rituximab-mediated antibody-dependent cellular cytotoxicity against chronic lymphocytic leukaemia
10.1038/leu.2015.88 · 2015 · External reference
Oncolytic virotherapy with an armed vaccinia virus in an orthotopic model of renal carcinoma is associated with modification of the tumor microenvironment
10.1080/2162402x.2015.1080414 · 2016 · External reference
The head and neck cancer immune landscape and its immunotherapeutic implications
10.1172/jci.insight.89829 · 2016 · External reference
Integrating conventional and antibody-based targeted anticancer treatment into immunotherapy
10.1038/onc.2016.231 · 2017 · External reference
CD4+ T cells are able to promote tumor growth through inhibition of tumor-specific CD8+ T-cell responses in tumor-bearing hosts
10.1158/0008-5472.can-04-3344 · 2005 · External reference
Antibody association with HER-2/neu-targeted vaccine enhances CD8 T cell responses in mice through Fc-mediated activation of DCs
10.1172/jci34333 · 2008 · External reference
Targeting the tumor microenvironment with interferon-β bridges innate and adaptive immune responses
10.1016/j.ccr.2013.12.004 · 2014 · External reference
Antitumor benefits of antiviral immunity: an underappreciated aspect of oncolytic virotherapies
10.1016/j.it.2017.11.006 · 2018 · External reference
The linkage of innate to adaptive immunity via maturing dendritic cells in vivo requires CD40 ligation in addition to antigen presentation and CD80/86 costimulation
10.1084/jem.20040317 · 2004 · External reference
Molecular-targeted therapies for epidermal growth factor receptor and its resistance mechanisms
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