Research graph
References from TRPM4 Expression as a Predictive Biomarker and a Mechanistic Driver of Acetalax Activity in Prostate Cancer: Preclinical Efficacy Studies. Local targets link to admitted publications; unresolved targets remain external evidence.
Global cancer statistics, 2012
2015 · External reference
Pembrolizumab for metastatic castration-resistant prostate cancer: trials and tribulations
10.1080/14712598.2024.2311750 · 2024 · External reference
Targeting the androgen receptor pathway in castration-resistant prostate cancer: progresses and prospects
10.1038/onc.2014.115 · 2015 · External reference
Abiraterone acetate plus prednisone in patients with newly diagnosed high-risk metastatic castration-sensitive prostate cancer (LATITUDE): final overall survival analysis of a randomised, double-blind, phase 3 trial
10.1016/s1470-2045(19)30082-8 · 2019 · External reference
Olaparib for metastatic castration-resistant prostate cancer
10.1056/nejmoa1911440 · 2020 · External reference
Rucaparib or physician’s choice in metastatic prostate cancer
10.1056/nejmoa2214676 · 2023 · External reference
Niraparib and abiraterone acetate for metastatic castration-resistant prostate cancer
10.1200/jco.22.01649 · 2023 · External reference
Gleason scores provide more accurate prognostic information than grade groups
10.1016/j.pathol.2024.12.633 · 2025 · External reference
Advanced prostate cancer survival in Spain according to the Gleason score, age and stage
10.1016/j.acuro.2016.03.008 · 2016 · External reference
Prostate cancer survival in the United States by race and stage (2001-2009): findings from the CONCORD-2 study
10.1002/cncr.31026 · 2017 · External reference
TRPM4 channel is involved in regulating epithelial to mesenchymal transition, migration, and invasion of prostate cancer cell lines
10.1002/jcp.27371 · 2019 · External reference
Transient receptor potential melastatin 4 channel contributes to migration of androgen-insensitive prostate cancer cells
10.18632/oncotarget.6157 · 2015 · External reference
Molecular features of the transition from prostatic intraepithelial neoplasia (PIN) to prostate cancer: genome-wide gene-expression profiles of prostate cancers and PINs
10.1158/0008-5472.can-04-0020 · 2004 · External reference
TRPM4 protein expression in prostate cancer: a novel tissue biomarker associated with risk of biochemical recurrence following radical prostatectomy
10.1007/s00428-015-1880-y · 2016 · External reference
A novel approach to identify driver genes involved in androgen-independent prostate cancer
10.1186/1476-4598-13-120 · 2014 · External reference
TRPM4 regulates Akt/GSK3-beta activity and enhances beta-catenin signaling and cell proliferation in prostate cancer cells
10.1002/1878-0261.12100 · 2018 · External reference
Oxyphenisatin acetate (NSC 59687) triggers a cell starvation response leading to autophagy, mitochondrial dysfunction, and autocrine TNFalpha-mediated apoptosis
10.1002/cam4.107 · 2013 · External reference
CellMinerCDB for integrative cross-database Genomics and pharmacogenomics analyses of cancer cell lines
10.1016/j.isci.2018.11.029 · 2018 · External reference
Acetalax (oxyphenisatin acetate, NSC 59687) and bisacodyl cause oncosis in triple-negative breast cancer cell lines by poisoning the ion exchange membrane protein TRPM4
10.1158/2767-9764.crc-24-0093 · 2024 · External reference
Acetalax and bisacodyl for the treatment of triple-negative breast cancer: a combined molecular and preclinical study
10.1158/2767-9764.crc-24-0435 · 2025 · External reference
CellMiner Cross-Database (CellMinerCDB) version 1.2: exploration of patient-derived cancer cell line pharmacogenomics
10.1093/nar/gkaa968 · 2021 · External reference
Unresolved reference
2019 · External reference
The Eighth Edition AJCC Cancer Staging Manual: continuing to build a bridge from a population-based to a more “personalized” approach to cancer staging
2017 · External reference
A pan-cancer survey of cell line tumor similarity by feature-weighted molecular profiles
10.1016/j.crmeth.2021.100039 · 2021 · External reference
Unresolved reference
2025 · External reference
STAR: ultrafast universal RNA-seq aligner
10.1093/bioinformatics/bts635 · 2013 · External reference
The Molecular Signatures Database (MSigDB) hallmark gene set collection
10.1016/j.cels.2015.12.004 · 2015 · External reference
Gene expression correlations in human cancer cell lines define molecular interaction networks for epithelial phenotype
10.1371/journal.pone.0099269 · 2014 · External reference
Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells
10.1126/science.1259418 · 2015 · External reference
Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancer
10.1038/s41467-021-24164-y · 2021 · External reference
