Research graph
References from Activity over Abundance: ADAMTSL4 Unlocks Latent TGFβ1 in Cancer Cachexia. Local targets link to admitted publications; unresolved targets remain external evidence.
Cachexia: a systemic consequence of progressive, unresolved disease
10.1016/j.cell.2023.03.028 · 2023 · External reference
10.1158/2159-8290.cd-26-0045 · 2026 · Admitted local publication
Secreted ADAMTS-like proteins as regulators of connective tissue function
10.1152/ajpcell.00680.2023 · 2024 · External reference
Excess TGF-β mediates muscle weakness associated with bone metastases in mice
10.1038/nm.3961 · 2015 · External reference
Transforming growth factor-β signaling in immunity and cancer
10.1016/j.immuni.2019.03.024 · 2019 · External reference
Thrombospondin-1 regulation of latent TGF-β activation: a therapeutic target for fibrotic disease
10.1016/j.matbio.2017.12.009 · 2018 · External reference
ADAMTSL4, a secreted glycoprotein widely distributed in the eye, binds fibrillin-1 microfibrils and accelerates microfibril biogenesis
10.1167/iovs.10-5955 · 2012 · External reference
The conserved ADAMTS-like protein lonely heart mediates matrix formation and cardiac tissue integrity
10.1371/journal.pgen.1003616 · 2013 · External reference
A dietary switch promotes sensory neuron-dependent cancer-associated cachexia
10.1126/science.adz4196 · 2026 · External reference