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References from Challenges in PT/INR harmonization across the total testing process. Local targets link to admitted publications; unresolved targets remain external evidence.
Review of coagulation preanalytical variables with update on the effect of direct oral anticoagulants.
10.1111/ijlh.13585 · 2021 · External reference
International Council for Standardization in Haematology (ICSH) recommendations for processing of blood samples for coagulation testing.
10.1111/ijlh.13702 · 2021 · External reference
International Normalized Ratios (INR): the first 20 years.
10.1111/j.1538-7836.2004.00775.x · 2004 · External reference
Standardization of Prothrombin Time/International Normalized Ratio (PT/INR).
10.1111/ijlh.13349 · 2021 · External reference
Defining a metrologically traceable and sustainable calibration hierarchy of international normalized ratio for monitoring of vitamin K antagonist treatment in accordance with International Organization for Standardization (ISO) 17511:2020 standard: communication from the International Federation of Clinical Chemistry and Laboratory Medicine-SSC/ISTH working group on prothrombin time/international normalized ratio standardization.
10.1016/j.jtha.2023.12.013 · 2024 · External reference
Paving the way for establishing a reference measurement system for standardization of plasma prothrombin time: Harmonizing the manual tilt tube method.
10.1111/jth.14873 · 2020 · External reference
Calibration of reference thromboplastins and standardisation of the prothrombin time ratio.
10.1055/s-0038-1657371 · 1983 · External reference
Standardization and harmonization in laboratory medicine: not only for clinical chemistry measurands.
10.1515/cclm-2022-1122 · 2022 · External reference
Comparison of optical and mechanical clot detection for routine coagulation testing in a large volume clinical laboratory.
10.1097/mbc.0b013e3283070872 · 2008 · External reference
Optical and mechanical clot detection methodologies: a comparison study for routine coagulation testing.
10.1002/jcla.21497 · 2012 · External reference
Validation of the Sysmex CS5100 coagulation analyzer and comparison to the Stago STA-R analyzer for routine coagulation parameters.
10.1111/ijlh.12295 · 2015 · External reference
A comparison of the optical method with the mechanical method in routine coagulation tests.
10.5937/jomb0-56100 · 2025 · External reference
Effects of haemolysis, icterus and lipaemia on coagulation tests as performed on Stago STA-Compact-Max analyser.
10.1111/ijlh.12498 · 2016 · External reference
Laboratory testing in patients treated with direct oral anticoagulants: a practical guide for clinicians.
10.1111/jth.13912 · 2018 · External reference
International Council for Standardization in Haematology (ICSH) Recommendations for Laboratory Measurement of Direct Oral Anticoagulants.
10.1055/s-0038-1627480 · 2018 · External reference
Laboratory Assessment of the Anticoagulant Activity of Direct Oral Anticoagulants: A Systematic Review.
10.1016/j.chest.2016.08.1462 · 2017 · External reference
Interlaboratory variability in assessment of the model of end-stage liver disease score.
10.1111/j.1478-3231.2008.01783.x · 2008 · External reference
Coagulation Testing in the Core Laboratory.
10.1093/labmed/lmx050 · 2017 · External reference
Pre-analytical Factors Influencing Blood Sample Rejection Rate in the Hematology Laboratory of the Philippine General Hospital from 2018 to 2022: A Cross-sectional Study.
2025 · External reference
Evaluation of errors in a clinical laboratory: A one-year experience.
10.1515/cclm.2010.006 · 2010 · External reference
The concept of rebalanced hemostasis in patients with liver disease: Communication from the ISTH SSC working group on hemostatic management of patients with liver disease.
10.1111/jth.15239 · 2021 · External reference
The effect of vitamin K on prothrombin time in critically ill patients: an observational registry study.
10.1186/s40560-020-00517-5 · 2021 · External reference
Sepsis-Induced Coagulopathy and Disseminated Intravascular Coagulation.
10.1055/s-0039-1694995 · 2020 · External reference
Mechanism of the anticoagulant effect of warfarin as evaluated in rabbits by selective depression of individual procoagulant vitamin K-dependent clotting factors.
10.1172/jci116814 · 1993 · External reference
The international normalized ratio to prioritize patients for liver transplantation: problems and possible solutions.
10.1111/j.1538-7933.2008.02827.x · 2008 · External reference
Consumptive coagulopathy is associated with a disturbed host response in patients with sepsis.
10.1111/jth.15246 · 2021 · External reference
Vitamin K: a potential missing link in critical illness-a scoping review.
10.1186/s13054-024-05001-2 · 2024 · External reference
International Council for Standardisation in Haematology (ICSH) recommendations for collection of blood samples for coagulation testing.
10.1111/ijlh.13584 · 2021 · External reference
Finish before the start: Analyzing preanalytical sample errors in a tertiary care hematology laboratory.
10.4103/ijpm.ijpm_191_19 · 2020 · External reference
Preanalytical Errors in a Hematology Laboratory: An Experience from a Tertiary Care Center.
2023 · External reference
Unresolved reference
External reference
Preanalytical Variables in Coagulation Testing: Setting the Stage for Accurate Results.
10.1055/s-0039-1692700 · 2019 · External reference
Validation of pre-analytical stability of specimens requested for various routine coagulation tests.
10.14345/ceth.21002 · 2021 · External reference
Quality standards for sample processing, transportation, and storage in hemostasis testing.
10.1055/s-0032-1319768 · 2012 · External reference
Guidelines on the laboratory aspects of assays used in haemostasis and thrombosis.
10.1111/bjh.16776 · 2020 · External reference
Quality indicators to detect pre-analytical errors in laboratory testing.
10.1016/j.cca.2013.07.033 · 2014 · External reference
Effect of anticoagulant adjustment on prothrombin time test using two different PT reagents in patients with elevated hematocrit.
2020 · External reference
Effects of storage time and temperature on coagulation factor and natural anticoagulant activities in healthy individuals.
10.1038/s41598-025-95389-w · 2025 · External reference
Measurement of heparin, direct oral anti-coagulants and other non-coumarin anti-coagulants and their effects on haemostasis assays: A British Society for Haematology Guideline.
10.1111/bjh.19729 · 2024 · External reference
Ultracentrifugation for Coagulation Testing.
10.1007/978-1-0716-3175-1_4 · 2023 · External reference
Standardization of the INR: how good is your laboratory’s INR and can it be improved?
10.1055/s-0028-1104538 · 2008 · External reference
Clinical usefulness of international normalized ratio calibration of prothrombin time in patients with chronic liver disease.
10.1007/s12185-015-1820-2 · 2015 · External reference
Unresolved reference
External reference
Guidelines for thromboplastins and plasma used to control oral anticoagulant therapy with vitamin K antagonists.
2013 · External reference
The international normalized ratio calibrated for cirrhosis (INR(liver)) normalizes prothrombin time results for model for end-stage liver disease calculation.
10.1002/hep.21732 · 2007 · External reference
Low-molecular-weight heparin in patients with advanced cirrhosis.
10.1111/j.1478-3231.2010.02358.x · 2011 · External reference
Calibrated automated thrombin generation measurement in clotting plasma.
10.1159/000071636 · 2003 · External reference
Evidence of normal thrombin generation in cirrhosis despite abnormal conventional coagulation tests.
10.1002/hep.20569 · 2005 · External reference
Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation.
10.1055/s-0037-1616068 · 2001 · External reference
The influence of the reference mean prothrombin time on the international normalized ratio.
10.1093/ajcp/102.6.806 · 1994 · External reference
Unresolved reference
External reference
Innovative Diagnostic Solutions in Hemostasis.
10.3390/diagnostics14222521 · 2024 · External reference
DOACs: role of anti-Xa and drug level monitoring.
10.1182/hematology.2024000666 · 2024 · External reference
DOAC-stop can remove direct oral anticoagulants and allow analysis by global coagulation assays.
10.1111/ijlh.14020 · 2023 · External reference
Novel Ex Vivo DOAC Removal Methods Reduce Interference in Lupus Anticoagulant Testing.
10.3390/diagnostics12102520 · 2022 · External reference
2021 update of the International Council for Standardization in Haematology recommendations for laboratory measurement of direct oral anticoagulants.
10.1055/a-1450-8178 · 2021 · External reference
2021 European Heart Rhythm Association Practical Guide on the Use of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation.
10.1093/europace/euab065 · 2021 · External reference
Machine Learning for Patient-Based Real-Time Quality Control (PBRTQC), Analytical and Preanalytical Error Detection in Clinical Laboratory.
10.3390/diagnostics14161808 · 2024 · External reference
Patient-based pre-classified real-time quality control with neural network (PCRTQC-NN).
2025 · External reference
Implementation of AI systems in the clinical laboratory: insights from an expert survey and recommendations for best practice.
10.1515/cclm-2025-1322 · 2026 · External reference
Decoding Clot Waveform Analysis: Toward Better Understanding and Harmonization.
10.1055/a-2778-9810 · 2026 · External reference
Regulating the future of laboratory medicine: European regulatory landscape of AI-driven medical device software in laboratory medicine.
10.1515/cclm-2025-0482 · 2025 · External reference
Regulatory Approved Point-of-Care Diagnostics (FDA & Health Canada): A Comprehensive Framework for Analytical Validity, Clinical Validity, and Clinical Utility in Medical Devices.
10.1093/jalm/jfaf106 · 2025 · External reference
Benefits and Pitfalls of Point-of-Care Coagulation Testing for Anticoagulation Management: An ACLPS Critical Review.
10.1093/ajcp/aqy087 · 2019 · External reference
Unresolved reference
External reference
ICSH guidance for INR and D-dimer testing using point of care testing in primary care.
10.1111/ijlh.14051 · 2023 · External reference
A Comprehensive Clinical Assessment of the LumiraDx International Normalized Ratio (INR) Assay for Point-of-Care Monitoring in Anticoagulation Therapy.
10.3390/diagnostics14232683 · 2024 · External reference
Unresolved reference
External reference
Efficacy of Point-of-Care for INR Testing Compared to Standard Laboratory Methods at a Tertiary Care Hospital in Saudi Arabia.
10.36401/jqsh-19-36 · 2020 · External reference
Unresolved reference
External reference
Warfarin monitoring with viscoelastic haemostatic assays, thrombin generation, coagulation factors and correlations to Owren and Quick prothrombin time.
10.1080/00365513.2018.1474492 · 2018 · External reference
During warfarin induction, the Fiix-prothrombin time reflects the anticoagulation level better than the standard prothrombin time.
10.1111/jth.13549 · 2017 · External reference
Replacement of traditional prothrombin time monitoring with the new Fiix prothrombin time increases the efficacy of warfarin without increasing bleeding. A review article.
10.1186/s12959-021-00327-1 · 2021 · External reference
Ignoring instead of chasing after coagulation factor VII during warfarin management: an interrupted time series study.
10.1182/blood.2020008698 · 2021 · External reference
Coagulation parameters reference interval for adult population of Debre Berhan town, Northeast Ethiopia.
10.1186/s12959-025-00808-7 · 2025 · External reference
Comparison of local International Sensitivity Index calibration and ‘Direct INR’ methods in correction of locally reported International Normalized Ratios: an international study.
10.1111/j.1538-7836.2007.02452.x · 2007 · External reference
Harmonizing the International Normalized Ratio (INR): standardization of methods and use of novel strategies to reduce interlaboratory variation and bias.
10.1093/ajcp/aqv022 · 2016 · External reference
Simplified method for international normalized ratio (INR) derivation based on the prothrombin time/INR line: an international study.
10.1373/clinchem.2009.141937 · 2010 · External reference
MELD 3.0: The Model for End-Stage Liver Disease Updated for the Modern Era.
10.1053/j.gastro.2021.08.050 · 2021 · External reference
Behind the scenes of EQA–characteristics, capabilities, benefits and assets of external quality assessment (EQA): Part IV – Benefits for participant laboratories.
10.1515/cclm-2024-1292 · 2025 · External reference
