Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Research graph
References from Exploratory Analysis of <i>APOE</i> ε4-Stratified Associations Between Plasma Alzheimer's Biomarkers and Retinal Imaging Metrics in Cognitively Normal Adults. Local targets link to admitted publications; unresolved targets remain external evidence.
New landscape of the diagnosis of Alzheimer's disease
10.1016/s0140-6736(25)01294-2 · 2025 · External reference
Biomarker changes during 20 years preceding Alzheimer's disease
10.1056/nejmoa2310168 · 2024 · External reference
APOE and Alzheimer's disease: advances in genetics, pathophysiology, and therapeutic approaches
10.1016/s1474-4422(20)30412-9 · 2021 · External reference
Spectral-domain OCT measurements in Alzheimer's disease: a systematic review and meta-analysis
10.1016/j.ophtha.2018.08.009 · 2019 · External reference
Changes in retinal microvasculature and retinal layer thickness in association with apolipoprotein E genotype in Alzheimer's disease
10.1038/s41598-020-80892-z · 2021 · External reference
Retinal imaging demonstrates reduced capillary density in clinically unimpaired APOE e4 gene carriers
2021 · External reference
Longitudinal analysis of the retina and choroid in cognitively normal individuals at higher genetic risk of Alzheimer disease
10.1016/j.oret.2022.03.001 · 2022 · External reference
Retinal biomarkers for early Alzheimer's detection: a systematic review of optical coherence tomography (OCT) findings
10.1136/bmjophth-2025-002328 · 2026 · External reference
Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup
10.1002/alz.13859 · 2024 · External reference
Association of retinal neurodegeneration on optical coherence tomography with dementia: a population-based study
10.1001/jamaneurol.2018.1563 · 2018 · External reference
Macular ganglion cell–inner plexiform layer thickness is associated with clinical progression in mild cognitive impairment and Alzheimers disease
10.1371/journal.pone.0162202 · 2016 · External reference
Association between retinal thickness and ß-amyloid brain accumulation in individuals with subjective cognitive decline: Fundació ACE Healthy Brain Initiative
10.1186/s13195-020-00602-9 · 2020 · External reference
Evaluation of inner retinal layers as biomarkers in mild cognitive impairment to moderate Alzheimer's disease
10.1371/journal.pone.0192646 · 2018 · External reference
Thicker macula in asymptomatic APOE e4 middle-aged adults at high AD risk
2022 · External reference
Macular thickness decrease in asymptomatic subjects at high genetic risk of developing Alzheimer's disease: an OCT study
10.3390/jcm9061728 · 2020 · External reference
Retinal ganglion cell vulnerability to pathogenic tau in Alzheimer's disease
10.1186/s40478-025-01935-y · 2025 · External reference
APOE4-driven lipid metabolic dysregulation in Alzheimer's disease: multi-pathway mechanisms and therapeutic perspectives
10.1016/j.bbrc.2025.152335 · 2025 · External reference
Apolipoprotein E4 expression causes gain of toxic function in isogenic human induced pluripotent stem cell-derived endothelial cells
10.1161/atvbaha.118.312261 · 2019 · External reference
APOE4, blood neurodegenerative biomarkers, and cognitive decline in community-dwelling older adults
10.1001/jamanetworkopen.2025.8903 · 2025 · External reference
Stage-specific links between plasma neurofilament light and imaging biomarkers of Alzheimer's disease
10.1093/brain/awaa342 · 2020 · External reference
Cognitively healthy APOE4/4 carriers show white matter impairment associated with serum NfL and amyloid-PET
10.1016/j.nbd.2024.106439 · 2024 · External reference
Elevated cerebral blood flow proxy with increased beta-amyloid burden in Alzheimer's disease preclinical phase evaluated by dual-phase 18F-florbetaben positron emission tomography
10.1038/s41598-024-68916-4 · 2024 · External reference
Regional hyperperfusion in older adults with objectively-defined subtle cognitive decline
10.1177/0271678x20935171 · 2021 · External reference
Compensatory retinal blood flow enhancement in cognitively normal ApoE e4 carriers
10.1038/s41598-025-16770-3 · 2025 · External reference
APOE e4 gene carriers demonstrate reduced retinal capillary densities in asymptomatic older adults
10.3390/jcm12175649 · 2023 · External reference
APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline
10.1038/s41586-020-2247-3 · 2020 · External reference
A “multi-omics” analysis of blood-brain barrier and synaptic dysfunction in APOE4 mice
10.1084/jem.20221137 · 2022 · External reference
Retinal microvascular changes in mild cognitive impairment and Alzheimer's disease: a systematic review, meta-analysis, and meta-regression
10.3389/fnagi.2022.860759 · 2022 · External reference
Apolipoprotein E e4 homozygosity exacerbates retinal and cerebral microvascular dysfunction in Alzheimer's disease: a mediation analysis of vascular contributions to cognitive decline
10.1002/alz.71000 · 2025 · External reference
Retinal microvascular alterations in Alzheimer's disease: linking blood plasma biomarkers and cerebral small vessel pathology
10.1002/alz.70745 · 2025 · External reference
Emerging oculomic signatures: linking thickness of entire retinal layers with plasma biomarkers in preclinical Alzheimer's disease
10.3390/jcm15010275 · 2025 · External reference
Association and multimodal model of retinal and blood-based biomarkers for detection of preclinical Alzheimer's disease
10.1186/s13195-024-01668-5 · 2025 · External reference
Ocular biomarkers for Alzheimer disease dementia: an umbrella review of systematic reviews and meta-analyses
10.1001/jamaophthalmol.2022.4845 · 2023 · External reference
Diagnostic performance of plasma pTau217/Aß42 ratio and a three-zone threshold model for Alzheimer's disease
10.1016/j.neurobiolaging.2025.12.005 · 2026 · External reference
Prediction of future Alzheimer's disease dementia using plasma phospho-tau combined with other accessible measures
10.1038/s41591-021-01348-z · 2021 · External reference