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References from Human HSPC clones balance stochastic diversification with cytokine-induced differentiation. Local targets link to admitted publications; unresolved targets remain external evidence.
Hematopoiesis: an evolving paradigm for stem cell biology
10.1016/j.cell.2008.01.025 · 2008 · External reference
A time- and single-cell-resolved model of murine bone marrow hematopoiesis
10.1016/j.stem.2023.12.001 · 2024 · External reference
Fundamental properties of unperturbed haematopoiesis from stem cells in vivo
10.1038/nature14242 · 2015 · External reference
Identification of clonogenic common lymphoid progenitors in mouse bone marrow
10.1016/s0092-8674(00)80453-5 · 1997 · External reference
Identification of a lineage of multipotent hematopoietic progenitors
10.1242/dev.124.10.1929 · 1997 · External reference
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
10.1038/35004599 · 2000 · External reference
Prospective isolation of human clonogenic common myeloid progenitors
10.1073/pnas.172384399 · 2002 · External reference
Distinct routes of lineage development reshape the human blood hierarchy across ontogeny
10.1126/science.aab2116 · 2016 · External reference
Human haematopoietic stem cell lineage commitment is a continuous process
10.1038/ncb3493 · 2017 · External reference
Hematopoietic hierarchy – an updated roadmap
10.1016/j.tcb.2018.06.001 · 2018 · External reference
Transitions in lineage specification and gene regulatory networks in hematopoietic stem/progenitor cells over human development
10.1016/j.celrep.2021.109698 · 2021 · External reference
Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction
10.1016/j.celrep.2022.110798 · 2022 · External reference
Unraveling hematopoiesis through the lens of genomics
10.1016/j.cell.2020.08.030 · 2020 · External reference
A reference model of circulating hematopoietic stem cells across the lifespan with applications to diagnostics
10.1038/s41591-025-03716-5 · 2025 · External reference
Single-cell characterization of haematopoietic progenitors and their trajectories in homeostasis and perturbed haematopoiesis
10.1038/s41556-018-0121-4 · 2018 · External reference
Hematopoietic cytokines
10.1182/blood-2007-03-079681 · 2008 · External reference
Hematopoietic cytokines can instruct lineage choice
10.1126/science.1171461 · 2009 · External reference
Inflammatory signaling regulates hematopoietic stem and progenitor cell development and homeostasis
10.1084/jem.20201545 · 2021 · External reference
Revision of the human hematopoietic tree: granulocyte subtypes derive from distinct hematopoietic lineages
10.1016/j.celrep.2013.04.025 · 2013 · External reference
Lineage tracing on transcriptional landscapes links state to fate during differentiation
10.1126/science.aaw3381 · 2020 · External reference
Unique molecular and functional features of extramedullary hematopoietic stem and progenitor cell reservoirs in humans
10.1182/blood.2021013450 · 2022 · External reference
Single-cell lineage tracing unveils a role for TCF15 in haematopoiesis
10.1038/s41586-020-2503-6 · 2020 · External reference
An engineered CRISPR/Cas9 mouse line for simultaneous readout of lineage histories and gene expression profiles in single cells
10.1016/j.cell.2020.06.018 · 2020 · External reference
Deciphering cell states and genealogies of human haematopoiesis
10.1038/s41586-024-07066-z · 2024 · External reference
A mouse model with high clonal barcode diversity for joint lineage, transcriptomic, and epigenomic profiling in single cells
10.1016/j.cell.2023.09.019 · 2023 · External reference
Pre-existing stem cell heterogeneity dictates clonal responses to the acquisition of leukemic driver mutations
10.1016/j.stem.2025.01.012 · 2025 · External reference
Metacell-2: a divide-and-conquer metacell algorithm for scalable scRNA-seq analysis
10.1186/s13059-022-02667-1 · 2022 · External reference
CellTagging: combinatorial indexing to simultaneously map lineage and identity at single-cell resolution
10.1038/s41596-019-0247-2 · 2020 · External reference
Unresolved reference
External reference
Characterization of cell fate probabilities in single-cell data with Palantir
10.1038/s41587-019-0068-4 · 2019 · External reference
Decoding human megakaryocyte development
10.1016/j.stem.2020.11.006 · 2021 · External reference
A single-cell framework identifies functionally and molecularly distinct multipotent progenitors in adult human hematopoiesis
10.1016/j.celrep.2025.116236 · 2025 · External reference
A mechanism to initiate emergency type 2 myelopoiesis
10.1038/s41586-026-10256-6 · 2026 · External reference
Multilineage gene expression precedes commitment in the hemopoietic system
10.1101/gad.11.6.774 · 1997 · External reference
Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment
10.1016/s1534-5807(02)00201-0 · 2002 · External reference
Integrative single-cell RNA-seq and ATAC-seq analysis of human developmental hematopoiesis
10.1016/j.stem.2020.11.015 · 2021 · External reference
Single-cell proteomics reveal that quantitative changes in co-expressed lineage-specific transcription factors determine cell fate
10.1016/j.stem.2019.02.006 · 2019 · External reference
Single-cell analysis of clonal maintenance of transcriptional and epigenetic states in cancer cells
10.1038/s41588-020-0645-y · 2020 · External reference
Memory sequencing reveals heritable single-cell gene expression programs associated with distinct cellular behaviors
10.1016/j.cell.2020.07.003 · 2020 · External reference
Chromatin-based memory as a self-stabilizing influence on cell identity
10.1186/s13059-024-03461-x · 2024 · External reference
Memory and relatedness of transcriptional activity in mammalian cell lineages
10.1038/s41467-019-09189-8 · 2019 · External reference
Gene-expression memory-based prediction of cell lineages from scRNA-seq datasets
10.1038/s41467-024-47158-y · 2024 · External reference
Reactivation of developmentally silenced globin genes by forced chromatin looping
10.1016/j.cell.2014.05.050 · 2014 · External reference
Promoter competition in globin gene control
10.1182/blood.2022015642 · 2022 · External reference
Elevating fetal hemoglobin: recently discovered regulators and mechanisms
10.1182/blood.2023022190 · 2024 · External reference
Distinct myeloid progenitor–differentiation pathways identified through single-cell RNA sequencing
10.1038/ni.3412 · 2016 · External reference
Identification of two distinct pathways of human myelopoiesis
10.1126/sciimmunol.aau7148 · 2019 · External reference
Single cell transcriptomics clarifies the basophil differentiation trajectory and identifies pre-basophils upstream of mature basophils
10.1038/s41467-023-38356-1 · 2023 · External reference
Concordant mast cell and basophil production by individual hematopoietic blast colony-forming cells
10.1073/pnas.1307711110 · 2013 · External reference
Antagonistic regulation by the transcription factors C/EBPα and MITF specifies basophil and mast cell fates
10.1016/j.immuni.2013.06.012 · 2013 · External reference
E-cadherin is regulated by GATA-2 and marks the early commitment of mouse hematopoietic progenitors to the basophil and mast cell fates
10.1126/sciimmunol.aba0178 · 2021 · External reference
A single-cell hematopoietic landscape resolves 8 lineage trajectories and defects in Kit mutant mice
10.1182/blood-2017-12-821413 · 2018 · External reference
