Research graph
References from Menin inhibitors unleash JUND-mediated resistance mechanisms. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1182/blood.2025032363 · 2026 · Admitted local publication
The MLL recombinome of acute leukemias in 2017
10.1038/leu.2017.213 · 2018 · External reference
The molecular functions of common and atypical MLL fusion protein complexes
10.1016/j.bbagrm.2020.194548 · 2020 · External reference
Germline mutations of the MEN1 gene in familial multiple endocrine neoplasia type 1 and related states
10.1093/hmg/6.7.1169 · 1997 · External reference
Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus
10.1016/s1097-2765(04)00081-4 · 2004 · External reference
Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression
10.1128/mcb.24.13.5639-5649.2004 · 2004 · External reference
The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis
10.1016/j.cell.2005.09.025 · 2005 · External reference
Targeting chromatin regulators inhibits leukemogenic gene expression in NPM1 mutant leukemia
10.1158/2159-8290.cd-16-0237 · 2016 · External reference
MEN1 mutations mediate clinical resistance to menin inhibition
10.1038/s41586-023-05755-9 · 2023 · External reference
Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription
10.1016/s0092-8674(00)80967-8 · 1999 · External reference
