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References from Genomic architecture of IRF4 rearrangements in childhood and adult large B-cell lymphomas. Local targets link to admitted publications; unresolved targets remain external evidence.
The International Consensus Classification of mature lymphoid neoplasms: a report from the Clinical Advisory Committee
10.1182/blood.2022015851 · 2022 · External reference
The 5th edition of the World Health Organization classification of haematolymphoid tumours: lymphoid neoplasms
10.1038/s41375-022-01620-2 · 2022 · External reference
Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults
10.1182/blood-2011-01-330795 · 2011 · External reference
Large B-cell lymphoma with IRF4 gene rearrangements: differences in clinicopathologic, immunophenotypic and cytogenetic features between pediatric and adult patients
10.1016/j.humpath.2022.10.011 · 2023 · External reference
Large B-cell lymphoma-IRF4+ in children and young people: time to reduce chemotherapy in a rare malignant mature B-cell neoplasm?
10.1182/bloodadvances.2023012109 · 2024 · External reference
The 2016 revision of the World Health Organization classification of lymphoid neoplasms
10.1182/blood-2016-01-643569 · 2016 · External reference
Distinct molecular profile of IRF4-rearranged large B-cell lymphoma
10.1182/blood.2019002699 · 2020 · External reference
IRF4 translocation status in pediatric follicular and diffuse large B-cell lymphoma patients enrolled in Children’s Oncology Group trials
10.1002/pbc.27770 · 2019 · External reference
Indolent lymphomas in the pediatric population: follicular lymphoma, IRF4/MUM1+ lymphoma, nodal marginal zone lymphoma and chronic lymphocytic leukemia
10.1007/s00428-015-1855-z · 2016 · External reference
Experience with provisional WHO-entities large B-cell lymphoma with IRF4-rearrangement and Burkitt-like lymphoma with 11q aberration in paediatric patients of the NHL-BFM group
10.1111/bjh.16578 · 2020 · External reference
IRF4 rearrangement may predict favorable prognosis in children and young adults with primary head and neck large B-cell lymphoma
10.1002/cam4.5828 · 2023 · External reference
Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma
10.1038/s41467-019-08578-3 · 2019 · External reference
Recurrent targets of aberrant somatic hypermutation in lymphoma
10.18632/oncotarget.653 · 2012 · External reference
Diffuse large B-cell lymphomas in adults with aberrant coexpression of CD10, BCL6, and MUM1 are enriched in IRF4 rearrangements
10.1182/bloodadvances.2021006034 · 2022 · External reference
Follicular lymphomas in children and young adults: a comparison of the pediatric variant with usual follicular lymphoma
10.1097/pas.0b013e31826b9b57 · 2013 · External reference
Non-IG::MYC in diffuse large B-cell lymphoma confers variable genomic configurations and MYC transactivation potential
10.1038/s41375-023-02134-1 · 2024 · External reference
Patient age at diagnosis is associated with the molecular characteristics of diffuse large B-cell lymphoma
10.1182/blood-2011-10-388470 · 2012 · External reference
Clinical relevance of molecular characteristics in Burkitt lymphoma differs according to age
10.1038/s41467-022-31355-8 · 2022 · External reference
Clinical impact of the subclonal architecture and mutational complexity in chronic lymphocytic leukemia
10.1038/leu.2017.291 · 2018 · External reference
MAPK and JAK-STAT pathways dysregulation in plasmablastic lymphoma
10.3324/haematol.2020.271957 · 2021 · External reference
MYC-rearranged mature B-cell lymphomas in children and young adults are molecularly Burkitt Lymphoma
10.1038/s41408-024-01153-0 · 2024 · External reference
Genomic and epigenomic insights into the origin, pathogenesis, and clinical behavior of mantle cell lymphoma subtypes
10.1182/blood.2020005289 · 2020 · External reference
Large B-cell lymphomas with CCND1 rearrangement have different immunoglobulin gene breakpoints and genomic profile than mantle cell lymphoma
10.1038/s41408-024-01146-z · 2024 · External reference
A probabilistic classification tool for genetic subtypes of diffuse large B cell lymphoma with therapeutic implications
10.1016/j.ccell.2020.03.015 · 2020 · External reference
RFcaller: a machine learning approach combined with read-level features to detect somatic mutations
10.1093/nargab/lqad056 · 2023 · External reference
Detection of early seeding of Richter transformation in chronic lymphocytic leukemia
10.1038/s41591-022-01927-8 · 2022 · External reference
Targeted chromatin profiling reveals novel enhancers in Ig H and Ig L chain loci
10.4049/jimmunol.1302800 · 2014 · External reference
A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma
10.1016/j.ccr.2007.08.011 · 2007 · External reference
Oncogenic CARD11 mutations in human diffuse large B cell lymphoma
2008 · External reference
SGK1 mutations in DLBCL generate hyperstable protein neoisoforms that promote AKT independence
10.1182/blood.2020010432 · 2021 · External reference
Mechanisms of chromosomal translocations in B cell lymphomas
10.1038/sj.onc.1204640 · 2001 · External reference
MicroRNA-142 is mutated in about 20% of diffuse large B-cell lymphoma
10.1002/cam4.29 · 2012 · External reference
Overexpression of miR-142-5p and miR-155 in gastric mucosa-associated lymphoid tissue (MALT) lymphoma resistant to Helicobacter pylori eradication
10.1371/journal.pone.0047396 · 2012 · External reference
Comprehensive miRNA sequence analysis reveals survival differences in diffuse large B-cell lymphoma patients
10.1186/s13059-014-0568-y · 2015 · External reference
Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center b-cell lymphomas determined by integrative sequencing analysis
10.3324/haematol.2016.143891 · 2016 · External reference
Ancient DNA: extraction, characterization, molecular cloning, and enzymatic amplification
10.1073/pnas.86.6.1939 · 1989 · External reference
Enforced expression of MIR142, a target of chromosome translocation in human B-cell tumors, results in B-cell depletion
10.1007/s12185-017-2360-8 · 2018 · External reference
Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes
10.1038/s41591-018-0016-8 · 2018 · External reference
Molecular alterations and tumor suppressive function of the DUSP22 (dual specificity phosphatase 22) gene in peripheral T-cell lymphoma subtypes
10.18632/oncotarget.11930 · 2016 · External reference
Discovery of recurrent t(6;7)(p25.3;q32.3) translocations in ALK-negative anaplastic large cell lymphomas by massively parallel genomic sequencing
10.1182/blood-2010-08-303305 · 2011 · External reference
Specificity through cooperation: BATF-IRF interactions control immune-regulatory networks
10.1038/nri3470 · 2013 · External reference
BATF is required for Treg homeostasis and stability to prevent autoimmune pathology
10.1002/advs.202206692 · 2023 · External reference
SPIB and BATF provide alternate determinants of IRF4 occupancy in diffuse large B-cell lymphoma linked to disease heterogeneity
10.1093/nar/gku451 · 2014 · External reference
False-negative rates for MYC fluorescence in situ hybridization probes in B-cell neoplasms
10.3324/haematol.2018.207290 · 2019 · External reference
Cryptic insertion of MYC exons 2 and 3 into the immunoglobulin heavy chain locus detected by whole genome sequencing in a case of “MYC-negative” Burkitt lymphoma
10.3324/haematol.2018.208140 · 2020 · External reference
Discordance between FISH, IHC, and NGS analysis of ALK status in advanced non–small cell lung cancer (NSCLC): a brief report of 7 cases
10.1016/j.tranon.2018.11.006 · 2019 · External reference
RNASeq analysis for accurate identification of fusion partners in tumor specific translocations detected by standard FISH probes in hematologic malignancies
10.1177/2632010x241230262 · 2024 · External reference
Transcriptional repression of bim by a novel YY1-RelA complex is essential for the survival and growth of multiple myeloma
10.1371/journal.pone.0066121 · 2013 · External reference
Deregulation of a possible tumour suppressor gene, ZC3H12D, by translocation of IGK@ in transformed follicular lymphoma with t(2;6)(p12;q25) [2]
10.1111/j.1365-2141.2007.06752.x · 2007 · External reference
Epstein–Barr virus status of sporadic Burkitt lymphoma is associated with patient age and mutational features
10.1111/bjh.17874 · 2022 · External reference
Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics
10.1038/nature11378 · 2012 · External reference
A unifying hypothesis for PNMZL and PTFL: morphological variants with a common molecular profile
10.1182/bloodadvances.2022007322 · 2022 · External reference
Mutations of MAP2K1 are frequent in pediatric-type follicular lymphoma and result in ERK pathway activation
10.1182/blood-2017-03-776278 · 2017 · External reference
High resolution copy number analysis of IRF4 translocation-positive diffuse large B-cell and follicular lymphomas
10.1002/gcc.22014 · 2013 · External reference
Emerging entities: high-grade/large B-cell lymphoma with 11q aberration, large B-cell lymphoma with IRF4 rearrangement, and new molecular subgroups in large B-cell lymphomas. A report of the 2022 EA4HP/SH lymphoma workshop
10.1007/s00428-023-03590-x · 2023 · External reference
Deletion of 17p in cancers: guilt by (p53) association
10.1038/s41388-025-03300-8 · 2025 · External reference
Biological heterogeneity in adult IRF4 -rearranged large B-cell lymphoma: Stratification by age and anatomical site
10.1002/hem3.70295 · 2026 · External reference