Research graph
References from Glycemic and psychosocial outcomes of automated insulin delivery in older and high-risk populations with type 1 diabetes: a systematic review and meta-analysis. Local targets link to admitted publications; unresolved targets remain external evidence.
Global burden of type 1 diabetes in adults aged 65 years and older, 1990-2019: population based study
10.1136/bmj-2023-078432 · 2024 · External reference
Hypoglycaemia symptoms and impaired awareness of hypoglycaemia in adults with type 1 diabetes: the association with diabetes duration
10.1111/dme.12496 · 2014 · External reference
Hypoglycemia in older adults with type 1 diabetes
10.1089/dia.2016.0268 · 2016 · External reference
Clinical targets for continuous glucose monitoring data interpretation: recommendations from the international consensus on time in range
10.2337/dci19-0028 · 2019 · External reference
Effect of continuous glucose monitoring on hypoglycemia in older adults with type 1 diabetes: a randomized clinical trial
10.1001/jama.2020.6928 · 2020 · External reference
Missed opportunities for risk reduction: type 1 diabetes management in older adults in DPV and T1DX-QI registries
10.1210/jendso/bvag007 · 2026 · External reference
Multicenter, randomized trial of a bionic pancreas in type 1 diabetes
10.1056/nejmoa2205225 · 2022 · External reference
Six-month randomized, multicenter trial of closed-loop control in type 1 diabetes
10.1056/nejmoa1907863 · 2019 · External reference
10.1016/j.eprac.2025.09.198
10.1016/j.eprac.2025.09.198 · External reference
Rob 2: a revised tool for assessing risk of bias in randomised trials
10.1136/bmj.l4898 · 2019 · External reference
ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions
10.1136/bmj.i4919 · 2016 · External reference
GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
10.1136/bmj.39489.470347.ad · 2008 · External reference
Unresolved reference
External reference
Time in range for multiple technologies in type 1 diabetes: a systematic review and network meta-analysis
10.2337/dc19-1785 · 2020 · External reference
Automated insulin delivery systems in children and adolescents with type 1 diabetes: a systematic review and meta-analysis of outpatient randomized controlled trials
10.2337/dc23-0504 · 2023 · External reference
Automated insulin delivery in young children with type 1 diabetes: a systematic review and meta-analysis
10.1210/clinem/dgag133 · 2026 · External reference
Optimally estimating the sample mean from the sample size, median, mid-range, and/or mid-quartile range
10.1177/0962280216669183 · 2018 · External reference
Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range
10.1186/1471-2288-14-135 · 2014 · External reference
Reduced awareness of hypoglycemia in adults with IDDM. A prospective study of hypoglycemic frequency and associated symptoms
10.2337/diacare.18.4.517 · 1995 · External reference
Assessing awareness of hypoglycemia in children and adolescents with type 1 diabetes: evaluation of established questionnaires
10.1111/pedi.12951 · 2020 · External reference
Closed-loop insulin delivery versus sensor-augmented pump therapy in older adults with type 1 diabetes (ORACL): a randomized, crossover trial
10.2337/dc21-1667 · 2022 · External reference
Hybrid closed-loop glucose control compared with sensor augmented pump therapy in older adults with type 1 diabetes: an open-label multicentre, multinational, randomised, crossover study
10.1016/s2666-7568(22)00005-8 · 2022 · External reference
Automated insulin delivery in older adults with type 1 diabetes
10.1056/evidoa2400200 · 2025 · External reference
Safety and efficacy of sustained automated insulin delivery compared with sensor and pump therapy in adults with type 1 diabetes at high risk for hypoglycemia: a randomized controlled trial
10.2337/dc23-0685 · 2023 · External reference
Hybrid closed-loop control is safe and effective for people with type 1 diabetes who are at moderate to high risk for hypoglycemia
10.1089/dia.2019.0018 · 2019 · External reference
Impact of hybrid closed loop therapy on hypoglycemia awareness in individuals with type 1 diabetes and impaired hypoglycemia awareness
10.1089/dia.2020.0593 · 2021 · External reference
Overnight glucose control with dual- and single-hormone artificial pancreas in type 1 diabetes with hypoglycemia unawareness: a randomized controlled trial
10.1089/dia.2017.0353 · 2018 · External reference
Hybrid closed loop in adults with type 1 diabetes and severely impaired hypoglycemia awareness
10.1177/19322968241245627 · 2025 · External reference
Glucose and counterregulatory responses to exercise in adults with type 1 diabetes and impaired awareness of hypoglycemia using closed-loop insulin delivery: a randomized crossover study
10.2337/dc19-1433 · 2020 · External reference
The impact of a recently approved automated insulin delivery system on glycemic, sleep, and psychosocial outcomes in older adults with type 1 diabetes: a pilot study
10.1177/1932296820986879 · 2022 · External reference
Closed-loop insulin therapy in older adults with type 1 diabetes: real-world data
10.1089/dia.2021.0311 · 2022 · External reference
Safety and performance of a hybrid closed-loop insulin delivery system with carbohydrate suggestion in adults with type 1 diabetes prone to hypoglycemia
10.1016/j.diabres.2023.110956 · 2023 · External reference
Switching to an advanced hybrid closed-loop system in real-world practice improves hypoglycemia awareness and metabolic control in adults with type 1 diabetes, particularly in those with impaired perception of hypoglycemia symptoms
10.1016/j.diabres.2023.110627 · 2023 · External reference
Prolonged use of an automated insulin delivery system improves sleep in long-standing type 1 diabetes complicated by impaired awareness of hypoglycemia
10.1177/19322968231182406 · 2024 · External reference
Advanced hybrid closed loop system use in elderly with type 1 diabetes: effectiveness and safety in a prospective, observational, 1-year follow-up real-world study
10.1111/dom.15055 · 2023 · External reference
A nationwide 12-month observatory of automated insulin delivery shows improved glucose control, sustained adoption, and reduced acute severe events
10.1111/dom.70302 · 2026 · External reference
Time spent in hypoglycemia according to age and time of day: observations during closed-loop insulin delivery
10.1089/dia.2023.0061 · 2023 · External reference
Beneficial effects of automated insulin delivery over one-year follow-up in real life for youths and adults with type 1 diabetes irrespective of patient characteristics
10.1111/dom.15344 · 2024 · External reference
Advanced hybrid closed-loop system achieves and maintains recommended time in range levels for up to 2 years: predictors of best efficacy
10.1089/dia.2023.0261 · 2024 · External reference
Long-term glycaemic improvement with the initiation of an automated insulin delivery system in insulin pump-naïve older adults with type 1 diabetes
10.1111/dom.15996 · 2025 · External reference
A real-world prospective study of the safety and effectiveness of the loop open source automated insulin delivery system
10.1089/dia.2020.0535 · 2021 · External reference
A multicenter randomized trial evaluating fast-acting insulin aspart in the bionic pancreas in adults with type 1 diabetes
10.1089/dia.2022.0167 · 2022 · External reference
Feasibility of a portable bihormonal closed-loop system to control glucose excursions at home under free-living conditions for 48 hours
10.1089/dia.2013.0166 · 2014 · External reference
Disconnect between advanced diabetes technology and psychological well-being among young people: a cross-sectional analysis
10.1136/bmjdrc-2025-005243 · 2025 · External reference
Decreasing the burden of carbohydrate counting and meal announcement with automated insulin delivery, meal recognition, and autocorrection doses: a case study
10.1089/dia.2023.0505 · 2024 · External reference
Impact of stepwise diabetes technology advances in older adults with type 1 diabetes: a systematic review and meta-analysis of randomised trials
10.1111/dom.70355 · 2026 · External reference