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References from Renoprotective Effects of Montelukast in Sepsis-Induced AKI: Targeting the NF-κB Pathway. Local targets link to admitted publications; unresolved targets remain external evidence.
Combination therapy of Ulinastatin with Thrombomodulin alleviates endotoxin (LPS)-induced liver and kidney injury via inhibiting apoptosis, oxidative stress and HMGB1/TLR4/NF-κB pathway.
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Pathological alteration and therapeutic implications of sepsis-induced immune cell apoptosis.
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Potential therapy strategy: targeting mitochondrial dysfunction in sepsis.
2018 · External reference
LPIN1 is a regulatory factor associated with immune response and inflammation in sepsis.
10.3389/fimmu.2022.820164 · 2022 · External reference
Inhibition of ITK signaling causes amelioration in sepsis-associated neuroinflammation and depression-like state in mice.
10.3390/ijms24098101 · 2023 · External reference
Subclinical kidney injury is caused by a moderate single inflammatory event.
10.1097/shk.0000000000001942 · 2022 · External reference
MicroRNAs in septic acute kidney injury. Burns.
10.1093/burnst/tkad008 · 2023 · External reference
Sepsis-associated acute kidney injury: consensus report of the 28th Acute Disease Quality Initiative workgroup.
10.1038/s41581-023-00683-3 · 2023 · External reference
Sepsis and acute kidne injury: a review focusing on the bidirectional interplay.
10.3390/ijms23169159 · 2022 · External reference
Toll-like receptors in sepsis-associated cytokine storm and their endogenous negative regulators as future immunomodulatory targets.
10.1016/j.intimp.2020.107087 · 2020 · External reference
Montelukast abrogates rhabdomyolysis induced acute renal failure via rectifying detrimental changes in antioxidant profile and systemic cytokines and apoptotic factors production.
10.1016/j.ejphar.2012.03.018 · 2012 · External reference
Leukotrienes, a potential target for Covid-19.
10.1016/j.plefa.2020.102174 · 2020 · External reference
Steroid-resistant idiopathic nephrotic syndrome in children: long-term follow-up and risk factors for end-stage renal disease.
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Effects of interleukin-13 and montelukast on the expression of zonula occludens-1 in human podocytes.
10.3349/ymj.2015.56.2.426 · 2015 · External reference
Ameliorative effect of montelukast against STZ induced diabetic nephropathy: targeting HMGB1, TLR4, NF-κB, NLRP3 inflammasome, and autophagy pathways.
10.1007/s10787-023-01301-1 · 2024 · External reference
Ginsenoside Rg1 attenuates cardiomyocyte apoptosis and inflammation via the TLR4/NF-κB/NLRP3 pathway.
10.1002/jcb.29556 · 2020 · External reference
Inflammation, NF-κB, and chronic diseases: how are they linked?
10.1615/critrevimmunol.2020033210 · 2020 · External reference
MiR-133a alleviates renal injury caused by sepsis by targeting BNIP3L.
10.26355/eurrev_202003_20532 · 2020 · External reference
The diagnostic and prognostic values of serum and urinary kidney injury molecule-1 and neutrophil gelatinase-associated lipocalin in sepsis induced acute renal injury patients.
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Basic principles and emerging concepts in the redox control of transcription factors.
10.1089/ars.2010.3534 · 2011 · External reference
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Cardioprotective Effects of Octreotide against Sepsis-Induced Cardiotoxicity in Mice.
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10.1093/ilar/ilab016 · 2021 · External reference
Amelioration of sepsis-induced hepatic and ileal injury in rats by the leukotriene receptor blocker Montelukast.
10.1016/j.plefa.2005.07.008 · 2005 · External reference
Blood sample collection in small laboratory animals.
10.4103/0976-500x.215702 · 2010 · External reference
Kaempferol Reverses Acute Kidney Injury in Septic Model by Inhibiting NF-κB/AKT Signaling Pathway.
10.1155/2023/1353449 · 2023 · External reference
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DUSP1 protects against ischemic acute kidney injury through stabilizing mtDNA via interaction with JNK.
10.1038/s41419-023-06247-4 · 2023 · External reference
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10.1016/j.procbio.2022.02.006 · 2022 · External reference
Epigenetic mechanisms in sepsis-associated acute kidney injury.
10.1055/s-0044-1789240 · 2024 · External reference
Determination of the safety and efficacy of therapeutic neutralization of tumor necrosis factor-α (TNF-α) using AZD9773, an anti-TNF-α immune Fab, in murine CLP sepsis.
10.1007/s00011-013-0683-3 · 2014 · External reference
GIP/GLP-1 dual agonist tirzepatide ameliorates renal ischemia/reperfusion damage in rats.
10.22159/ijap.2025v17i2.53156 · 2025 · External reference
Effects of CDDO-EA in sepsis-induced acute lung injury: mouse model of endotoxemia.
10.36740/wlek202403119 · 2024 · External reference
Nephroprotective role of resveratrol in renal ischemia-reperfusion injury: a preclinical study in Sprague-Dawley rats. BMC.
10.1186/s40360-024-00809-8 · 2024 · External reference
Montelukast attenuates lipopolysaccharide-induced cardiac injury in rats.
10.1177/0960327115591372 · 2016 · External reference
Inhibition of sepsis-induced pancreatic injury by leukotriene receptor antagonism via modulation of oxidative injury, and downregulation of inflammatory markers in experimental rats. Naunyn Schmiedeberg’s.
10.1007/s00210-023-02812-y · 2024 · External reference
Survivin and caspases serum protein levels and survivin variants mRNA expression in sepsis.
2021 · External reference
Potential nephroprotective effect of dapagliflozin against renal ischemia reperfusion injury in rats via activation of autophagy pathway and inhibition of inflammation, oxidative stress and apoptosis.
10.70135/seejph.vi.1009 · 2024 · External reference
Trandolapril improves renal ischemia-reperfusion injury in adult male rats via activation of the autophagy pathway and inhibition of inflammation, oxidative stress, and apoptosis.
10.21608/jbaar.2024.315239.1077 · 2024 · External reference
Renoprotective effects of montelukast in an experimental model of cisplatin nephrotoxicity in rats.
10.1002/jbt.21979 · 2017 · External reference
Cardioprotective Potential of Celastrol in Sepsis-Induced Cardiotoxicity; Mouse Model of Endotoxemia.
2023 · External reference
The anti-inflammatory and antioxidant effects of Montelukast on lung sepsis in adult mice.
2022 · External reference
Lyn attenuates sepsis-associated acute kidney injury by inhibition of phospho-STAT3 and apoptosis.
10.1016/j.bcp.2023.115523 · 2023 · External reference
Montelukast inhibits RANKL-induced osteoclast formation and bone loss via CysLTR1 and P2Y12.
10.3892/mmr.2018.9179 · 2018 · External reference
Extracellular signal–regulated kinase 1/2 regulates mouse kidney injury molecule-1 expression physiologically and following ischemic and septic renal injury.
10.1124/jpet.117.244152 · 2017 · External reference
Maresin 1 Mitigates Sepsis-Associated Acute Kidney Injury in Mice via Inhibition of the NF-κB/STAT3/MAPK Pathways.
10.3389/fphar.2019.01323 · 2019 · External reference
Improvement of renal functions in mice with septic acute kidney injury using secretome of mesenchymal stem cells.
10.1016/j.sjbs.2024.103931 · 2024 · External reference
Montelukast reduces sepsis-induced lung and renal injury in rats.
10.1139/cjpp-2014-0191 · 2014 · External reference
Excel data Montelukast.
10.6084/m9.figshare.28599605.v2 · 2025 · External reference
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10.6084/m9.figshare.29150939 · 2025 · External reference