Research graph
References from How Innate Immune Mechanisms Contribute to the Chronic Nature of COPD?. Local targets link to admitted publications; unresolved targets remain external evidence.
DAMPs activating innate and adaptive immune responses in COPD.
10.1038/mi.2013.77 · 2014 · External reference
Detection of Chronic Obstructive Pulmonary Disease among Smokers Aged ≥40 years Attending Primary Health Care Centers in Baghdad-AL-Karkh and AL-Resafa.
10.32007/jfacmedbagdad.6441936 · 2023 · External reference
Prevalence and determinants of chronic obstructive pulmonary disease among a sample of adult smokers in Baghdad, Iraq, 2014.
10.26719/2017.23.2.67 · 2017 · External reference
Association of a Disintegrin and Metalloproteinase33 Gene Polymorphisms with Chronic Obstructive Pulmonary Disease in Iraqi Population.
10.26452/ijrps.v9ispl1.1355 · 2018 · External reference
Prevalence of Chronic Non-Communicable Respiratory Diseases in Mosul City.
10.47836/mjmhs.20.1.27 · 2024 · External reference
Neutrophil-derived peptidyl arginine deiminase activity contributes to pulmonary emphysema by enhancing elastin degradation.
10.4049/jimmunol.2300658 · 2024 · External reference
Association between airway MMP-12 and DNA methylation in BAL cells in COPD.
10.1183/13993003.congress-2023.oa4240 · 2023 · External reference
Oxidative stress biomarkers in chronic obstructive pulmonary disease exacerbations: a systematic review.
10.3390/antiox10050710 · 2021 · External reference
Neutrophil elastase in the pathogenesis of chronic obstructive pulmonary disease: a review.
10.2174/1573398x18666220929170117 · 2022 · External reference
Initiatives to improve outcomes for chronic obstructive pulmonary disease.
2005 · External reference
Improving the management of chronic obstructive pulmonary disease.
10.1111/j.1945-1474.2005.tb01116.x · 2005 · External reference
Therapeutic targeting of MMP-12 for the treatment of chronic obstructive pulmonary disease.
10.1021/acs.jmedchem.0c01285 · 2020 · External reference
Matrix metalloproteinases in chronic obstructive pulmonary disease.
10.3390/ijms24043786 · 2023 · External reference
RETHINCking COPD - Bronchodilators for Symptomatic Tobacco-Exposed Persons with Preserved Lung Function?
10.1056/nejme2210347 · 2022 · External reference
The prevalence of and risk factors for non-smoking chronic obstructive pulmonary disease in china: A systematic review and meta-analysis.
10.1183/13993003.congress-2023.pa5305 · 2023 · External reference
COPD: a multifactorial systemic disease.
10.1177/1753465811400490 · 2011 · External reference
Interaction study of the effects of environmental exposure and gene polymorphisms of inflammatory and immune-active factors on chronic obstructive pulmonary disease.
10.1186/s12931-024-03079-4 · 2025 · External reference
The Burden of Chronic Obstructive Pulmonary Disease COPD in Stable Patients and its Association with Inflammatory Biomarkers and Body Mass Index.
10.32007/jfacmedbagdad.6642284 · 2024 · External reference
Unveiling the dynamic role of innate and adaptive immune cells in COPD pathogenesis induced by cigarette smoke.
10.33687/liferes.007.04.5262 · 2024 · External reference
The dynamic lung microbiome in health and disease.
10.1038/s41579-022-00821-7 · 2023 · External reference
Dying to defend: neutrophil death pathways and their implications in immunity.
10.1002/advs.202306457 · 2024 · External reference
Innate immunity and chronic obstructive pulmonary disease: a mini-review.
10.1159/000354173 · 2013 · External reference
Neutrophilic inflammation in the pathogenesis of chronic obstructive pulmonary disease.
10.1080/15412555.2018.1476475 · 2018 · External reference
Neutrophil elastase as a biomarker for bacterial infection in COPD.
10.1186/s12931-019-1145-4 · 2019 · External reference
Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice.
10.1126/science.277.5334.2002 · 1997 · External reference
Expressions of MMP-12, TIMP-4, and neutrophil elastase in PBMCs and exhaled breath condensate in patients with COPD and their relationships with disease severity and acute exacerbations.
10.1155/2019/7142438 · 2019 · External reference
Sputum elastase in steady-state bronchiectasis.
10.1378/chest.117.2.420 · 2000 · External reference
Neutrophil elastase activity is associated with exacerbations and lung function decline in bronchiectasis.
10.1164/rccm.201605-1027oc · 2017 · External reference
Infection in the pathogenesis and course of chronic obstructive pulmonary disease.
10.1056/nejmra0800353 · 2008 · External reference
S114 Hypoxia drives neutrophil-mediated endothelial damage in COPD.
10.1136/thoraxjnl-2017-210983.120 · 2017 · External reference
Neutrophil elastase activates macrophage calpain as a mechanism for phagocytic failure.
10.1152/ajplung.00132.2024 · 2024 · External reference
Neutrophil elastase and chronic lung disease.
10.3390/biom11081065 · 2021 · External reference
Damage-associated molecular patterns control neutrophil recruitment.
10.1159/000347132 · 2013 · External reference
Cellular and molecular choreography of neutrophil recruitment to sites of sterile inflammation.
10.1007/s00109-011-0784-9 · 2011 · External reference
Alpha1-antitrypsin deficiency.
10.1056/nejmra1910234 · 2020 · External reference
Human neutrophil elastase-mediated cleavage sites of MMP-9 and TIMP-1: implications to cystic fibrosis proteolytic dysfunction.
10.2119/molmed.2009.00109 · 2010 · External reference
Neutrophil elastase contributes to cigarette smoke-induced emphysema in mice.
10.1016/s0002-9440(10)63589-4 · 2003 · External reference
Malondialdehyde as a potential oxidative stress marker for allergy-oriented diseases: an update.
10.3390/molecules28165979 · 2023 · External reference
10.5772/intechopen.1006338
10.5772/intechopen.1006338 · 2024 · External reference
Cytokine dysregulation in pulmonary tuberculosis: The role of TNF-α/IL-10 and TNF-α/TGF-β ratios as severity indicators.
10.1016/j.humimm.2025.111256 · 2025 · External reference
How Innate Immune Mechanisms Contribute to the Chronic Nature of COPD?.
10.6084/m9.figshare.30398827 · 2025 · External reference