Research graph
References from Hackathon on predictive modelling in systems pharmacology: design, implementation, and outcomes. Local targets link to admitted publications; unresolved targets remain external evidence.
SCENIC: Single-cell regulatory network inference and clustering.
10.1038/nmeth.4463 · 2017 · External reference
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1.
10.1038/nature08460 · 2009 · External reference
SMOTE for high-dimensional class-imbalanced data.
10.1186/1471-2105-14-106 · 2013 · External reference
Model-Based Meta-Analysis With MonolixSuite: A Tutorial for Longitudinal Categorical and Continuous Data.
10.1002/psp4.70158 · 2026 · External reference
Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma.
10.1038/s41591-020-0839-y · 2020 · External reference
Discovering the anticancer potential of non-oncology drugs by systematic viability profiling.
10.1038/s43018-019-0018-6 · 2020 · External reference
Network propagation: A universal amplifier of genetic associations.
10.1038/nrg.2017.38 · 2017 · External reference
ChEMBL web services: Streamlining access to drug discovery data and utilities.
10.1093/nar/gkv352 · 2015 · External reference
Convergence of a Stochastic Approximation Version of the EM Algorithm.
10.1214/aos/1018031103 · 1999 · External reference
New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1).
10.1016/j.ejca.2008.10.026 · 2009 · External reference
GSEApy: A comprehensive package for performing gene set enrichment analysis in Python.
10.1093/bioinformatics/btac757 · 2023 · External reference
Nonlinear Mixed-Effects Model Development and Simulation Using nlmixr and Related R Open-Source Packages.
10.1002/psp4.12445 · 2019 · External reference
Integration of the Drug–Gene Interaction Database (DGIdb 4.0) with open crowdsource efforts.
10.1093/nar/gkaa1084 · 2021 · External reference
Next-generation characterization of the Cancer Cell Line Encyclopedia.
10.1038/s41586-019-1186-3 · 2019 · External reference
Improving drug response prediction by integrating multiple data sources: Matrix factorization, kernel and network-based approaches.
10.1093/bib/bbz153 · 2021 · External reference
A Landscape of Pharmacogenomic Interactions in Cancer.
10.1016/j.cell.2016.06.017 · 2016 · External reference
Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response.
10.1038/s41591-018-0136-1 · 2018 · External reference
Modelling and analysis of gene regulatory networks.
10.1038/nrm2503 · 2008 · External reference
Modeling and Simulation Workbench for NONMEM: Tutorial on Pirana, PsN, and Xpose.
10.1038/psp.2013.24 · 2013 · External reference
The Molecular Signatures Database Hallmark Gene Set Collection.
10.1016/j.cels.2015.12.004 · 2015 · External reference
Wisdom of crowds for robust gene network inference.
10.1038/nmeth.2016 · 2012 · External reference
From time-series transcriptomics to gene regulatory networks: A review on inference methods.
10.1371/journal.pcbi.1011254 · 2023 · External reference
Hackathon on predictive modelling in systems pharmacology: design, implementation, and outcomes.
10.5281/zenodo.21494545 · 2026 · External reference
Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma.
10.1056/nejmoa1510665 · 2015 · External reference
Basic Concepts in Population Modeling, Simulation, and Model-Based Drug Development.
10.1038/psp.2012.4 · 2012 · External reference
Determining cell type abundance and expression from bulk tissues with digital cytometry.
10.1038/s41587-019-0114-2 · 2019 · External reference
Studies on coumarin anticoagulant drugs. Initiation of warfarin therapy without a loading dose.
10.1161/01.cir.38.1.169 · 1968 · External reference
Pharmacogenomics in the clinic.
10.1038/nature15817 · 2015 · External reference
Drug sensitivity prediction from cell line-based pharmacogenomics data: Guidelines for developing machine learning models.
10.1093/bib/bbab294 · 2021 · External reference
An NIH White Paper by the QSP Workshop Group – October, 201.
2011 · External reference
New Strategies in Renal Cell Carcinoma: Targeting the Genetic and Metabolic Basis of Disease.
10.1158/1078-0432.ccr-13-2993 · 2015 · External reference
Random walk with restart on multiplex and heterogeneous biological networks.
10.1093/bioinformatics/bty637 · 2019 · External reference
Systems Pharmacology: Bridging Systems Biology and Pharmacokinetics-Pharmacodynamics (PKPD) in Drug Discovery and Development.
10.1007/s11095-011-0467-9 · 2011 · External reference
Digital pharmacological twins: Bridging multi-scale modelling and artificial intelligence for precision medicine: The DIGPHAT consortium.
10.1016/j.therap.2025.09.006 · 2025 · External reference
Integrative Single-Cell Analysis Reveals Transcriptional and Epigenetic Regulatory Features of Clear Cell Renal Cell Carcinoma.
10.1158/0008-5472.can-22-2224 · 2023 · External reference
