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References from Genomic evidence for the parallel regression of melatonin synthesis and signaling pathways in placental mammals. Local targets link to admitted publications; unresolved targets remain external evidence.
Extrapineal melatonin: Sources, regulation, and potential functions.
10.1007/s00018-014-1579-2 · 2014 · External reference
Evolution by gene loss.
10.1038/nrg.2016.39 · 2016 · External reference
High-quality carnivoran genomes from roadkill samples enable comparative species delineation in aardwolf and bat-eared fox.
10.7554/elife.63167 · 2021 · External reference
Melatonin replacement restores the circadian behavior in adult rat Leydig cells after pinealectomy.
10.1016/j.mce.2015.05.039 · 2015 · External reference
Preliminary investigations on melatonin and 5-methoxytryptophol synthesis in the pineal, retina, and Harderian gland of the mole rat and in the pineal of the mouse “eyeless.”
10.1007/bf01252129 · 1980 · External reference
The pineal organ (Epiphysis cerebri) of the harbour porpoise Phocoena phocoena. (Linné, 1758).
1990 · External reference
Independent erosion of conserved transcription factor binding sites points to shared hindlimb, vision and external testes loss in different mammals.
10.1093/nar/gky741 · 2018 · External reference
The ultrastructure of mammalian pinealocytes: A systematic investigation.
10.1002/jemt.1070210203 · 1992 · External reference
The sites and consequences of melatonin binding in mammals.
10.1093/icb/33.2.200 · 1993 · External reference
Effects of pinealectomy and exogenous melatonin on serum leptin levels in male rat.
10.1016/s0014-2999(01)01230-4 · 2001 · External reference
Observations on the structure of the manatee.
1875 · External reference
Melatonin, energy metabolism, and obesity: A review.
10.1111/jpi.12137 · 2014 · External reference
Melatonin as a hormone: New physiological and clinical insights.
10.1210/er.2018-00084 · 2018 · External reference
Daily differential expression of melatonin-related genes and clock genes in rat cumulus-oocyte complex: Changes after pinealectomy.
10.1111/jpi.12234 · 2015 · External reference
Influence of pinealectomy on plasma and extrapineal melatonin rhythms in young chickens (Gallus domesticus).
10.1016/0016-6480(87)90073-6 · 1987 · External reference
Adaptive loss of ultraviolet-sensitive/violet-sensitive (UVS/VS) cone opsin in the blind mole rat (Spalax ehrenbergi).
10.1046/j.1460-9568.2002.02161.x · 2002 · External reference
Pinealectomy interferes with the circadian clock genes expression in white adipose tissue.
10.1111/jpi.12211 · 2015 · External reference
Pinealectomy inhibits interleukin-2 production and natural killer activity in mice.
10.1016/0192-0561(89)90187-2 · 1989 · External reference
Morphological and molecular evidence for a stepwise evolutionary transition from teeth to baleen in mysticete whales.
10.1080/10635150701884632 · 2008 · External reference
MUSCLE: Multiple sequence alignment with high accuracy and high throughput.
10.1093/nar/gkh340 · 2004 · External reference
Regressed but not gone: Patterns of vision gene loss and retention in subterranean mammals.
10.1093/icb/icy004 · 2018 · External reference
Genomic regression of claw keratin, taste receptor and light-associated genes provides insights into biology and evolutionary origins of snakes.
10.1016/j.ympev.2017.07.014 · External reference
Archelosaurian color vision, parietal eye loss, and the crocodylian nocturnal bottleneck.
10.1093/molbev/msw265 · External reference
Spectral shifts of mammalian ultravioletsensitive pigments (Short wavelengthsensitive opsin 1) are associated with eye length and photic niche evolution.
10.1098/rspb.2015.1817 · 2015 · External reference
Genomic evidence for rod monochromacy in sloths and armadillos suggests early subterranean history for Xenarthra.
10.1098/rspb.2014.2192 · 2015 · External reference
Eyes underground: Regression of visual protein networks in subterranean mammals.
10.1016/j.ympev.2014.05.016 · 2014 · External reference
Genomic evidence for the parallel regression of the melatonin pathway in placental mammals (Version 1) [Data set]. Open Research Europe
2021 · External reference
Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax.
10.1038/ncomms4966 · 2014 · External reference
Melatonin rhythms in the Australian freshwater crocodile (Crocodylus johnstoni): a reptile lacking a pineal complex?
10.1007/s00360-009-0387-8 · 2010 · External reference
Plasma melatonin levels in the scincid lizard Trachydosaurus rugosus: The effects of parietal eye and lateral eye impairment.
10.1242/jeb.85.1.311 · 1980 · External reference
Pinealectomy induces malformation of the spine and reduces the mechanical strength of the vertebrae in Atlantic salmon, Salmo salar.
10.1046/j.1600-079x.2003.00109.x · 2004 · External reference
Contribution of pineal and retinae to the circadian rhythms of circulating melatonin in pigeons.
10.1007/bf00612714 · 1988 · External reference
Seasonal difference of diurnal variations in serum melatonin, cortisol, testosterone, and rectal temperature in Indo-Pacific bottlenose dolphins (Tursiops aduncus).
10.1578/am.37.4.2011.433 · 2011 · External reference
Inactivation of thermogenic UCP1 as a historical contingency in multiple placental mammal clades.
10.1126/sciadv.1602878 · 2017 · External reference
Plasma melatonin in the neotenic tiger salamander (Ambystoma tigrinum): Effects of photoperiod and pinealectomy.
10.1016/0016-6480(79)90147-3 · 1979 · External reference
The synthesis of melatonin by the trout retina.
10.1002/jez.1402060217 · External reference
Persistence of the nychthemeral rhythm of melatonin secretion in pinealectomized or optic tract‐sectioned trout (Salmo gairdneri).
10.1002/jez.1402050305 · External reference
Shotgun mitogenomics provides a reference phylogenetic framework and timescale for living xenarthrans.
10.1093/molbev/msv250 · 2016 · External reference
Parietal eyes in lizards: Zoogeographical correlates.
10.1126/science.1237930 · 1975 · External reference
Annual pineal and testicular cycle in the indian jungle bush quail, Perdicula asiatica, with reference to the effect of pinealectomy.
10.1016/0016-6480(90)90216-9 · 1990 · External reference
Non-vertebrate melatonin.
10.1034/j.1600-079x.2003.00040.x · 2003 · External reference
Circadian rhythms and the effects of exogenous melatonin in the nine-banded armadillo, Dasypus novemcinctus: A mammal lacking a distinct pineal gland.
10.1016/0031-9384(82)90020-8 · 1982 · External reference
Day-night rhythm in plasma melatonin in a mammal lacking a distinct pineal gland, the nine-banded armadillo.
10.1016/0016-6480(81)90106-4 · 1981 · External reference
Identification of melatonin in plants and its effects on plasma melatonin levels and binding to melatonin receptors in vertebrates.
1995 · External reference
Talpid mole phylogeny unites shrew moles and illuminates overlooked cryptic species diversity.
10.1093/molbev/msw221 · 2017 · External reference
Paleogenomics illuminates the evolutionary history of the extinct Holocene “horned” crocodile of Madagascar, Voay robustus.
10.1038/s42003-021-02017-0 · 2021 · External reference
Melatonin stimulates growth of brown adipose tissue.
10.1038/247224a0 · 1974 · External reference
Photoperiodic control and effects of melatonin on nonshivering thermogenesis and brown adipose tissue.
10.1126/science.7233183 · 1981 · External reference
Morphologie und mikroskopische Anatomie des Gehirns beim fetalen Narwal, Monodon monoceros.
1991 · External reference
Genes lost during the transition from land to water in cetaceans highlight genomic changes involved in aquatic adaptations.
10.1101/521617 · 2019 · External reference
Thermoregulatory function of the parietal eye in the lizard Anolis carolinensis.
10.1007/bf00345581 · 1974 · External reference
The brain of the tree pangolin (Manis tricuspis). V. The diencephalon and hypothalamus.
10.1002/cne.24619 · 2019 · External reference
Geneious Basic: An integrated and extendable desktop software platform for the organization and analysis of sequence data.
10.1093/bioinformatics/bts199 · 2012 · External reference
A specific radioimmunoassay for melatonin in biological tissue and fluids and its validation by gas chromatography-mass spectrometry.
10.1210/endo-101-1-119 · 1977 · External reference
Circadian rhythms of dopamine and dihydroxyphenyl acetic acid in the mouse striatum: Effects of pinealectomy and of melatonin treatment.
10.1159/000048238 · 2002 · External reference
Genome sequencing reveals insights into physiology and longevity of the naked mole rat.
10.1038/nature10533 · 2011 · External reference
TimeTree: A Resource for Timelines, Timetrees, and Divergence Times.
10.1093/molbev/msx116 · 2017 · External reference
Progressive loss of function in a limb enhancer during snake evolution.
10.1016/j.cell.2016.09.028 · 2016 · External reference
Étude des corrélations liant le volume de l’épiphyse aux poids somatique et encéphalique chez les rongeurs, les insectivores, les chiropteres, les prosimiens et les simiens.
10.1515/mamm.1976.40.2.327 · 1976 · External reference
Pinealectomy causes glucose intolerance and decreases adipose cell responsiveness to insulin in rats.
10.1152/ajpendo.1998.275.6.e934 · 1998 · External reference
The singularity of Cetacea behavior parallels the complete inactivation of melatonin gene modules.
10.3390/genes10020121 · 2019 · External reference
Cetacean sleep: An unusual form of mammalian sleep.
10.1016/j.neubiorev.2008.05.023 · 2008 · External reference
Melatonin excretion of man and rats: Effect of time of day, sleep, pinealectomy and food consumption.
10.1007/bf01451037 · 1975 · External reference
Genomic analysis reveals hidden biodiversity within colugos, the sister group to primates.
10.1126/sciadv.1600633 · 2016 · External reference
Ventricular system of the brain of the dolphin, Tursiops truncatus, with comparative anatomical observations and relations to brain specializations.
10.1002/cne.901350304 · 1969 · External reference
Phylogenomic resolution of the cetacean tree of life using target sequence capture.
10.1093/sysbio/syz068 · 2020 · External reference
Molecular decay of the tooth gene enamelin (ENAM) mirrors the loss of enamel in the fossil record of placental mammals.
10.1371/journal.pgen.1000634 · 2009 · External reference
Impacts of the Cretaceous Terrestrial Revolution and KPg extinction on mammal diversification.
10.1126/science.1211028 · 2011 · External reference
Evidence for a single loss of mineralized teeth in the common avian ancestor.
10.1126/science.1254390 · 2014 · External reference
Creating the CIPRES Science Gateway for inference of large phylogenetic trees.
10.1109/gce.2010.5676129 · 2010 · External reference
V. On the form and structure of the manatee (Manatus americanus).
10.1111/j.1469-7998.1872.tb08571.x · 1872 · External reference
Molecular basis for regulating seasonal reproduction in vertebrates.
10.1530/joe-16-0066 · 2016 · External reference
Morphology and evolutionary biology of the dolphin (Delphinus sp.) brain--MR imaging and conventional histology.
10.1159/000110495 · 2008 · External reference
Survey of the development and comparative morphology of the pineal organ.
10.1016/s0079-6123(08)63445-7 · 1965 · External reference
The pineal gland and melatonin in sea turtles.
1985 · External reference
Evidence of melatonin secretion in cetaceans: Plasma concentration and extrapineal HIOMT-like presence in the bottlenose dolphin Tursiops truncatus.
10.1016/j.ygcen.2012.04.012 · 2012 · External reference
Subterranean mammals show convergent regression in ocular genes and enhancers, along with adaptation to tunneling.
10.7554/elife.25884 · 2017 · External reference
Dietary factors and fluctuating levels of melatonin.
10.3402/fnr.v56i0.17252 · 2012 · External reference
The pineal gland of the mole (Talpa europaea L.) I. The fine structure of the pinealocytes.
10.1007/bf00229159 · 1974 · External reference
The ultrastructure of pinealocytes in the golden mole (Amblysomus hottentotus) with special reference to the granular vesicles.
10.1007/bf00223214 · 1978 · External reference
Elevation of upper voluntary temperatures after shielding the parietal eye of horned lizards (Phrynosoma douglassi).
1981 · External reference
Epithalamus of the nine-banded armadillo, Dasypus novemcinctus.
10.1016/0300-9629(86)90433-0 · 1986 · External reference
Relative size of brain and brain components in three gliding placentals (Dermoptera: Rodentia).
10.1139/z82-084 · 1982 · External reference
Pineal atrophy and other neuroendocrine and circumventricular features of the naked mole-rat, Heterocephalus glaber (Rüppell), a fossorial, equatorial rodent.
10.1007/bf01253102 · 1981 · External reference
The pineal gland and geographical distribution of animals.
10.1007/bf01451040 · 1975 · External reference
Does the manatee have a pineal body?
10.1111/j.1463-6395.1985.tb00647.x · 1985 · External reference
Melatonin in walnuts: Influence on levels of melatonin and total antioxidant capacity of blood.
10.1016/j.nut.2005.02.005 · 2005 · External reference
Characterization of the day-night variation of retinal melatonin content in the chick.
1983 · External reference
Nonpineal melatonin in the alligator (Alligator mississippiensis).
10.1126/science.7423204 · 1980 · External reference
Convergent regulatory evolution and loss of flight in paleognathous birds.
10.1126/science.aat7244 · 2019 · External reference
The pineal gland from development to function.
10.1016/b978-0-12-416021-7.00005-5 · 2013 · External reference
Interordinal gene capture, the phylogenetic position of Steller’s sea cow based on molecular and morphological data, and the macroevolutionary history of Sirenia.
10.1016/j.ympev.2015.05.022 · 2015 · External reference
Inactivation of C4orf26 in toothless placental mammals.
10.1016/j.ympev.2015.11.002 · 2016 · External reference
RAxML version 8: A tool for phylogenetic analysis and post-analysis of large phylogenies.
10.1093/bioinformatics/btu033 · 2014 · External reference
The role of the “third eye” in reptilian behavior.
1958 · External reference
Gene expression of the key enzymes of melatonin synthesis in extrapineal tissues of the rat.
10.1034/j.1600-079x.2001.300408.x · 2001 · External reference
Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release.
10.1073/pnas.1705768114 · 2017 · External reference
On the significance of an alternate pathway of melatonin synthesis via 5-methoxytryptamine: comparisons across species.
10.1111/jpi.12336 · 2016 · External reference
Fundamental issues related to the origin of melatonin and melatonin isomers during evolution: Relation to their biological functions.
10.3390/ijms150915858 · 2014 · External reference
Melatonin rhythms in the eyes, pineal bodies, and blood of Japanese quail (Coturnix coturnix japonica).
10.1016/0016-6480(84)90063-7 · 1984 · External reference
The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system.
10.1073/pnas.1314702110 · 2013 · External reference
PAML 4: Phylogenetic analysis by maximum likelihood.
10.1093/molbev/msm088 · 2007 · External reference
Melatonin synthesis and function: Evolutionary history in animals and plants.
10.3389/fendo.2019.00249 · 2019 · External reference