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References from Engineering Polymeric Vectors for Nucleic Acid Delivery: Linking Molecular Architecture, Biological Function, and Computational Design. Local targets link to admitted publications; unresolved targets remain external evidence.
Viral vector platforms within the gene therapy landscape.
10.1038/s41392-021-00487-6 · 2021 · External reference
Technological advances in the use of viral and non-viral vectors for delivering genetic and non-genetic cargos for cancer therapy.
10.1007/s13346-023-01362-3 · 2023 · External reference
Design, preparation and application of nucleic acid delivery carriers.
10.1016/j.biotechadv.2013.11.004 · 2014 · External reference
Recent advances in exosome-mediated nucleic acid delivery for cancer therapy.
10.1186/s12951-022-01472-z · 2022 · External reference
Polymers as Efficient Non-Viral Gene Delivery Vectors: The Role of the Chemical and Physical Architecture of Macromolecules.
10.3390/polym16182629 · 2024 · External reference
Non-viral vectors for gene-based therapy.
10.1038/nrg3763 · 2014 · External reference
Research Advances in Nucleic Acid Delivery System for Rheumatoid Arthritis Therapy.
10.3390/pharmaceutics15041237 · 2023 · External reference
Recent Advances in Nonviral Vectors for Gene Delivery.
10.1021/ar200151m · 2012 · External reference
Landscape of small nucleic acid therapeutics: moving from the bench to the clinic as next-generation medicines.
10.1038/s41392-024-02112-8 · 2025 · External reference
Polyplex Evolution: Understanding Biology, Optimizing Performance.
10.1016/j.ymthe.2017.01.024 · 2017 · External reference
Polymer-mediated gene therapy: Recent advances and merging of delivery techniques.
10.1002/wnan.1598 · 2020 · External reference
Polymeric delivery systems for nucleic acid therapeutics: Approaching the clinic.
10.1016/j.jconrel.2021.01.014 · 2021 · External reference
Lipid nanoparticles for mRNA delivery.
10.1038/s41578-021-00358-0 · 2021 · External reference
Beyond Lipids: Exploring Advances in Polymeric Gene Delivery in the Lipid Nanoparticles Era.
10.1002/adma.202404608 · 2024 · External reference
Blended Block Polycation Micelles Enhance Antisense Oligonucleotide Delivery.
10.1021/acs.bioconjchem.3c00186 · 2023 · External reference
Lyophilization provides long-term stability for a lipid nanoparticle-formulated, nucleoside-modified mRNA vaccine.
10.1016/j.ymthe.2022.02.001 · 2022 · External reference
Continuous freeze-drying of messenger RNA lipid nanoparticles enables storage at higher temperatures.
10.1016/j.jconrel.2023.03.039 · 2023 · External reference
A novel mechanism for the loss of mRNA activity in lipid nanoparticle delivery systems.
10.1038/s41467-021-26926-0 · 2021 · External reference
Leveraging Biological Buffers for Efficient Messenger RNA Delivery via Lipid Nanoparticles.
10.1021/acs.molpharmaceut.2c00587 · 2022 · External reference
Emerging non-viral vectors for gene delivery.
10.1186/s12951-023-02044-5 · 2023 · External reference
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2021 · External reference
Recent progress in polymeric gene vectors: Delivery mechanisms, molecular designs, and applications.
10.1063/5.0123664 · 2023 · External reference
Nucleic Acid Delivery Nanotechnologies for In Vivo Cell Programming.
10.1021/acsabm.3c00886 · 2024 · External reference
Nucleic acid delivery for therapeutic applications.
10.1016/j.addr.2021.113834 · 2021 · External reference
Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer.
10.1002/jgm.598 · 2004 · External reference
Cationic Polymer Based Gene Delivery Systems.
10.1023/a:1007548826495 · 2000 · External reference
Effect of cationic carriers on the pharmacokinetics and tumor localization of nucleic acids after intravenous administration.
10.1016/j.ijpharm.2006.10.029 · 2007 · External reference
CLINICAL TRIALS AND TRANSLATIONAL MEDICINE COMMENTARY: Drug Delivery Trends in Clinical Trials and Translational Medicine: Challenges and Opportunities in the Delivery of Nucleic Acid-Based Therapeutics.
10.1002/jps.22243 · 2011 · External reference
Decreased Binding to Proteins and Cells of Polymeric Gene Delivery Vectors Surface Modified with a Multivalent Hydrophilic Polymer and Retargeting through Attachment of Transferrin*.
10.1074/jbc.275.6.3793 · 2000 · External reference
Succinylated Polyethylenimine Derivatives Greatly Enhance Polyplex Serum Stability and Gene Delivery In Vitro.
10.1021/acs.biomac.8b01248 · 2018 · External reference
PEG shielded MMP sensitive CPPs for efficient and tumor specific gene delivery in vivo.
10.1016/j.jconrel.2015.04.038 · 2015 · External reference
C3-dependent effector functions of complement.
10.1111/imr.13147 · 2023 · External reference
A guide to complement biology, pathology and therapeutic opportunity.
10.1038/s41577-023-00926-1 · 2024 · External reference
The polyplex, protein corona, cell interplay: Tips and drawbacks.
10.1016/j.colsurfb.2018.01.040 · 2018 · External reference
Advances in the polymeric delivery of nucleic acid vaccines.
10.7150/thno.70853 · 2022 · External reference
Endocytosis in cellular uptake of drug delivery vectors: Molecular aspects in drug development.
10.1016/j.bmc.2020.115556 · 2020 · External reference
Nanoparticle-Based Drug Delivery for Vascular Applications.
10.3390/bioengineering11121222 · 2024 · External reference
Extracellular Vesicle Transportation and Uptake by Recipient Cells: A Critical Process to Regulate Human Diseases.
10.3390/pr9020273 · 2021 · External reference
Recent advances in extracellular vesicles for therapeutic cargo delivery.
10.1038/s12276-024-01201-6 · 2024 · External reference
Nucleic Acid Therapeutics Using Polyplexes: A Journey of 50 Years (and Beyond).
10.1021/cr5006793 · 2015 · External reference
Polyplex: A Promising Gene Delivery System.
10.37285//ijpsn.2019.12.6.1 · 2019 · External reference
The great escape: how cationic polyplexes overcome the endosomal barrier.
10.1039/c8tb00967h · 2018 · External reference
Quantitating Endosomal Escape of a Library of Polymers for mRNA Delivery.
10.1021/acs.nanolett.9b04426 · 2020 · External reference
Engineering poly- and micelleplexes for nucleic acid delivery - A reflection on their endosomal escape.
10.1016/j.jconrel.2022.12.008 · 2023 · External reference
The Biology of Endosomal Escape: Strategies for Enhanced Delivery of Therapeutics.
10.1021/acsnano.5c18112 · External reference
Advanced Strategies for Overcoming Endosomal/Lysosomal Barrier in Nanodrug Delivery.
External reference
Size-dependent DNA Mobility in Cytoplasm and Nucleus *.
10.1074/jbc.275.3.1625 · 2000 · External reference
Mechanisms and functions of nuclear envelope remodelling.
10.1038/nrm.2016.153 · 2017 · External reference
10.1021/bm0605863
10.1021/bm0605863 · 2006 · External reference
Biodegradable nanoparticles composed of dendrigraft poly-l-lysine for gene delivery.
10.1016/j.ejpb.2014.04.013 · 2014 · External reference
Design of Free Triblock Polylysine- b-Polyleucine- b-Polylysine Chains for Gene Delivery.
10.1021/acs.biomac.8b00287 · 2018 · External reference
Chemo-physical and biological evaluation of poly(L-lysine)-grafted chitosan copolymers used for highly efficient gene delivery.
10.1002/mabi.201000283 · 2011 · External reference
Polylysine-modified polyethylenimine inducing tumor apoptosis as an efficient gene carrier.
10.1016/j.jconrel.2013.06.026 · 2013 · External reference
Polylysine-modified polyethylenimine polymer can generate genetically engineered mesenchymal stem cells for combinational suicidal gene therapy in glioblastoma.
10.1016/j.actbio.2018.09.015 · 2018 · External reference
A summary on non-viral systems for gene delivery based on natural and synthetic polymers.
10.1080/00914037.2020.1825081 · 2022 · External reference
Hepatocyte-targeting gene transfer mediated by galactosylated poly (ethylene glycol)-graft-polyethylenimine derivative.
10.2147/dddt.s42582 · 2013 · External reference
In situ preparation of non-viral gene vectors with folate/magnetism dual targeting by hyperbranched polymers.
10.1016/j.eurpolymj.2020.109584 · 2020 · External reference
TAT modified and lipid – PEI hybrid nanoparticles for co-delivery of docetaxel and pDNA.
10.1016/j.biopha.2016.10.003 · 2016 · External reference
Hyperbranched poly (ethylenimine-co-oxazoline) by thiol–yne chemistry for non-viral gene delivery: investigating the role of polymer architecture.
10.1039/c8py01648h · 2019 · External reference
Polyethylenimine based magnetic nanoparticles mediated non-viral CRISPR/Cas9 system for genome editing.
10.1038/s41598-020-61465-6 · 2020 · External reference
Polyethylenimine-functionalized graphene oxide as an efficient gene delivery vector.
10.1039/c1jm10341e · 2011 · External reference
Engineering PAMAM dendrimers for optimized drug delivery.
10.1016/j.nwnano.2025.100094 · 2025 · External reference
Dendrimer Prodrugs.
10.3390/molecules21060686 · 2016 · External reference
Preparation of gene drug delivery systems of cationic peptide lipid with 0G-PAMAM as hydrophilic end and its biological properties evaluation.
10.1016/j.chemphyslip.2018.09.009 · 2019 · External reference
Synthesis and Analytical Characterization of Ester and Amine Terminated PAMAM Dendrimers.
2013 · External reference
Enhanced Delivery of Plasmid DNA to Skeletal Muscle Cells using a DLC8-Binding Peptide and ASSLNIA-Modified PAMAM Dendrimer.
10.1021/acs.molpharmaceut.8b01313 · 2019 · External reference
Dendrimer as nanocarrier for drug delivery.
10.1016/j.progpolymsci.2013.07.005 · 2014 · External reference
Polyamidoamine (PAMAM) Dendrimers Modified with Cathepsin-B Cleavable Oligopeptides for Enhanced Gene Delivery.
10.3390/polym9060224 · 2017 · External reference
A novel disulfide bond-mediated cleavable RGD-modified PAMAM nanocomplex containing nuclear localization signal HMGB1 for enhancing gene transfection efficiency.
10.2147/ijn.s182445 · 2018 · External reference
Hydroxyl PAMAM dendrimer-based gene vectors for transgene delivery to human retinal pigment epithelial cells.
10.1039/c4nr04284k · 2015 · External reference
Dendrimer-based drug and imaging conjugates: design considerations for nanomedical applications.
10.1016/j.drudis.2010.01.009 · 2010 · External reference
Half generations magnetic PAMAM dendrimers as an effective system for targeted gemcitabine delivery.
10.1016/j.ijpharm.2016.10.015 · 2016 · External reference
Modified PAMAM vehicles for effective TRAIL gene delivery to colon adenocarcinoma: in vitro and in vivo evaluation.
10.1080/21691401.2018.1500372 · 2018 · External reference
Glycosylation of PAMAM dendrimers significantly improves tumor macrophage targeting and specificity in glioblastoma.
10.1016/j.jconrel.2021.07.018 · 2021 · External reference
A reactive oxygen species-responsive dendrimer with low cytotoxicity for efficient and targeted gene delivery.
10.1016/j.cclet.2019.03.040 · 2020 · External reference
Zwitterion-functionalized dendrimer-entrapped gold nanoparticles for serum-enhanced gene delivery to inhibit cancer cell metastasis.
10.1016/j.actbio.2019.09.005 · 2019 · External reference
Low generation PAMAM-based nanomicelles as ROS-responsive gene vectors with enhanced transfection efficacy and reduced cytotoxicity in vitro.
10.1039/c6nj04129a · 2017 · External reference
Pyrrolidone Modification Prevents PAMAM Dendrimers from Activation of Pro-Inflammatory Signaling Pathways in Human Monocytes.
10.1021/acs.molpharmaceut.7b00515 · 2017 · External reference
In Vitro Evaluation of Third Generation PAMAM Dendrimer Conjugates.
10.3390/molecules22101661 · 2017 · External reference
Degradable Poly(β-amino esters): Synthesis, Characterization, and Self-Assembly with Plasmid DNA.
10.1021/ja0015388 · 2000 · External reference
A Combinatorial Polymer Library Approach Yields Insight into Nonviral Gene Delivery.
10.1021/ar7002336 · 2008 · External reference
Structure/property studies of polymeric gene delivery using a library of poly (beta-amino esters).
10.1016/j.ymthe.2004.11.015 · 2005 · External reference
Natural Polymeric Nanoparticles for Brain-Targeting: Implications on Drug and Gene Delivery.
10.2174/1381612822666160204120829 · 2016 · External reference
Biodegradable Polymer Nanogels for Drug/Nucleic Acid Delivery.
10.1021/cr500131f · 2015 · External reference
Chitosan—A versatile semi-synthetic polymer in biomedical applications.
10.1016/j.progpolymsci.2011.02.001 · 2011 · External reference
Chitosan-based formulations for delivery of DNA and siRNA.
10.1016/j.addr.2009.08.004 · 2010 · External reference
Chitosan for gene delivery: Methods for improvement and applications.
10.1016/j.cis.2019.03.007 · 2019 · External reference
Chemical Modification of Chitosan as a Gene Transporter.
10.2174/1385272821666170926163544 · 2018 · External reference
Chitosan and its derivatives: vectors in gene therapy.
10.1070/rcr4636 · 2017 · External reference
A spermine conjugated stearic acid-g-chitosan oligosaccharide polymer with different types of amino groups for efficient p53 gene therapy.
10.1016/j.colsurfb.2016.05.071 · 2016 · External reference
Effect of Proteins with Different Isoelectric Points on the Gene Transfection Efficiency Mediated by Stearic Acid Grafted Chitosan Oligosaccharide Micelles.
10.1021/mp300732d · 2013 · External reference
Delivery of MicroRNAs by Chitosan Nanoparticles to Functionally Alter Macrophage Cholesterol Efflux in vitro and in Vivo.
10.1021/acsnano.8b09679 · 2019 · External reference
Targeted delivery of microRNA-126 to vascular endothelial cells via REDV peptide modified PEG-trimethyl chitosan.
10.1039/c5bm00629e · 2016 · External reference
Pullulan-hyperproducing color variant strain of Aureobasidium pullulans FB-1 newly isolated from phylloplane of Ficus sp.
10.1016/j.biortech.2007.08.003 · 2008 · External reference
Production of the Polysaccharide Pullulan by Aureobasidium pullulans Cell Immobilization.
10.3390/polysaccharides3030032 · 2022 · External reference
Randomized phase II clinical trial of NY-ESO-1 protein vaccine combined with cholesteryl pullulan (CHP-NY-ESO-1) in resected esophageal cancer patients.
10.1093/annonc/mdz253.040 · 2019 · External reference
Evidence for receptor-mediated hepatic uptake of pullulan in rats.
10.1016/s0168-3659(00)00368-0 · 2001 · External reference
Liver-targeted siRNA delivery by polyethylenimine (PEI)-pullulan carrier.
10.1016/j.bmc.2010.04.031 · 2010 · External reference
Novel folated and non-folated pullulan bioconjugates for anticancer drug delivery.
10.1016/j.ejps.2011.02.012 · 2011 · External reference
Efficient targeted pDNA/siRNA delivery with folate–low-molecular-weight polyethyleneimine–modified pullulan as non-viral carrier.
10.1016/j.msec.2013.08.035 · 2014 · External reference
Synthesis of cationic quaternized pullulan derivatives for miRNA delivery.
10.1016/j.ijpharm.2020.119041 · 2020 · External reference
Liver targeting of plasmid DNA by pullulan conjugation based on metal coordination.
10.1016/s0168-3659(02)00201-8 · 2002 · External reference
Modified pullulan unlocks efficient polyplex-mediated gene silencing following nebulization.
10.1016/j.ijbiomac.2026.153787 · 2026 · External reference
Hydrogel pullulan nanoparticles encapsulating pBUDLacZ plasmid as an efficient gene delivery carrier.
10.1016/j.jconrel.2004.06.016 · 2004 · External reference
Application of dextran as nanoscale drug carriers.
10.2217/nnm-2018-0331 · 2018 · External reference
Cationised dextran and pullulan modified with diethyl aminoethyl methacrylate for gene delivery in cancer cells.
10.1016/j.carbpol.2020.116426 · 2020 · External reference
Self-assembled nanocomposites of carboxymethyl β-dextran/protamine sulfate for enhanced chemotherapeutic drug sensitivity of triple-negative breast cancer by autophagy inhibition via a ternary collaborative strategy.
10.1016/j.ijbiomac.2023.123663 · 2023 · External reference
PSMA-specific degradable dextran for multiplexed immunotargeted siRNA therapeutics against prostate cancer.
10.1039/d2nr02200a · 2022 · External reference
Acid-degradable Dextran as an Image Guided siRNA Carrier for COX-2 Downregulation.
10.7150/thno.21052 · 2018 · External reference
Nano polyelectrolyte complexes of carboxymethyl dextran and chitosan to improve chitosan-mediated delivery of miR-145.
10.1016/j.carbpol.2016.11.067 · 2017 · External reference
Glutathione responsive chitosan-thiolated dextran conjugated miR-145 nanoparticles targeted with AS1411 aptamer for cancer treatment.
10.1016/j.carbpol.2018.08.060 · 2018 · External reference
Acid-Degradable Cationic Dextran Particles for the Delivery of siRNA Therapeutics.
10.1021/bc100542r · 2011 · External reference
Hyaluronic Acid Conjugated Magnetic Prussian Blue@Quantum Dot Nanoparticles for Cancer Theranostics.
10.7150/thno.17411 · 2017 · External reference
Selective delivery of PLXDC1 small interfering RNA to endothelial cells for anti-angiogenesis tumor therapy using CD44-targeted chitosan nanoparticles for epithelial ovarian cancer.
10.1080/10717544.2018.1480672 · 2018 · External reference
Hyaluronic Acid and Its Derivatives in Coating and Delivery Systems: Applications in Tissue Engineering, Regenerative Medicine and Immunomodulation.
10.1002/adhm.201600316 · 2016 · External reference
Role of Biomaterials and Controlled Architecture on Tendon/Ligament Repair and Regeneration.
10.1002/adma.201904511 · 2020 · External reference
Degradable poly (ethylene glycol) (PEG)-based hydrogels for spatiotemporal control of siRNA/nanoparticle delivery.
10.1016/j.jconrel.2018.08.002 · 2018 · External reference
pH-Responsive Studies of Bacterial Cellulose/Chitosan Hydrogels Crosslinked with Genipin: Swelling and Drug Release Behaviour.
10.1002/slct.201902290 · 2019 · External reference
Three-dimensional fibrous PLGA/HAp composite scaffold for BMP-2 delivery.
10.1002/bit.21517 · 2008 · External reference
Microparticulate poly (vinyl alcohol) hydrogel formulations for embedding and controlled release of polyethylenimine (PEI)-based nanoparticles.
10.1016/j.actbio.2016.08.056 · 2016 · External reference
Biodegradable gelatin hydrogel potentiates the angiogenic effect of fibroblast growth factor 4 plasmid in rabbit hindlimb ischemia.
10.1016/s0735-1097(02)03007-3 · 2003 · External reference
Design of Biodegradable Hydrogel for the Local and Sustained Delivery of Angiogenic Plasmid DNA.
10.1007/s11095-007-9526-7 · 2008 · External reference
Peptide-matrix-mediated gene transfer of an oxygen-insensitive hypoxia-inducible factor-1alpha variant for local induction of angiogenesis.
10.1073/pnas.0505964102 · 2006 · External reference
Polyelectrolyte Complexes of Low Molecular Weight PEI and Citric Acid as Efficient and Nontoxic Vectors for in vitro and in vivo Gene Delivery.
10.1021/acs.bioconjchem.5b00576 · 2016 · External reference
Enhancing the in vitro and in vivo Stabilities of Polymeric Nucleic Acid Delivery Nanosystems.
10.1021/acs.bioconjchem.8b00749 · 2019 · External reference
Recent developments of polymeric delivery systems in gene therapeutics.
10.1039/d4py00124a · 2024 · External reference
Relationship between phosphorylamine-modification and molecular weight on transfection efficiency of chitosan.
10.1016/j.carbpol.2021.118870 · 2022 · External reference
Efficient polycation non-viral gene delivery system with high buffering capacity and low molecular weight for primary cells: Branched poly(β-aminoester) containing primary, secondary and tertiary amine groups.
10.1016/j.eurpolymj.2022.111046 · 2022 · External reference
Macromolecular Gene Delivery Systems: Advancing Non-viral Therapeutics with Synthetic and Natural Polymers.
2025 · External reference
Cationic Polymers for Gene Delivery: Properties and Functional Optimization.
External reference
Influence of Macromer Molecular Weight and Chemistry on Poly(β-amino ester) Network Properties and Initial Cell Interactions.
10.1002/jbm.a.31494 · 2008 · External reference
Silane and amino acid functionalized PBAEs for enhanced gene Delivery: Synthesis, characterization, and transfection efficiency.
10.1016/j.jddst.2025.106990 · 2025 · External reference
Amino acid derived biopolymers: Recent advances and biomedical applications.
10.1016/j.ijbiomac.2021.08.036 · 2021 · External reference
Recent advances in poly (amino acids), polypeptides, and their derivatives in drug delivery.
10.1039/d4nr04481a · 2025 · External reference
Poly(β-amino ester)s-based nanovehicles: Structural regulation and gene delivery.
10.1016/j.omtn.2023.04.019 · 2023 · External reference
The transition from linear to highly branched poly(β-amino ester)s: Branching matters for gene delivery.
10.1126/sciadv.1600102 · 2016 · External reference
Combinatorial Modification of Degradable Polymers Enables Transfection of Human Cells Comparable to Adenovirus.
10.1002/adma.200700371 · 2007 · External reference
The Synthesis of Cyclic Poly (ethylene imine) and Exact Linear Analogues: An Evaluation of Gene Delivery Comparing Polymer Architectures.
10.1021/jacs.5b00980 · 2015 · External reference
Bioengineered nanovesicles for efficient siRNA delivery through ligand-receptor-mediated and enzyme-controlled membrane fusion.
10.1038/s41467-025-61230-1 · 2025 · External reference
In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight.
10.1038/nnano.2014.84 · 2014 · External reference
Artificial Intelligence (AI)-Aided Structure Optimization for Enhanced Gene Delivery: The Effect of the Polymer Component Distribution (PCD).
10.1021/acsami.3c05010 · 2023 · External reference
Realizing the Clinical Potential of Cancer Nanotechnology by Minimizing Toxicologic and Targeted Delivery Concerns.
10.1158/0008-5472.can-12-1527 · 2012 · External reference
The Effect of Nanoparticle Size on In Vivo Pharmacokinetics and Cellular Interaction.
10.2217/nnm.16.5 · 2016 · External reference
Nanodrug Delivery: Is the Enhanced Permeability and Retention Effect Sufficient for Curing Cancer?.
10.1021/acs.bioconjchem.6b00437 · 2016 · External reference
Effect of Polyplex Size on Penetration into Tumor Spheroids.
10.1021/acs.molpharmaceut.3c00397 · 2023 · External reference
Novel Oligo-Guanidyl-PEG Carrier Forming Rod-Shaped Polyplexes.
10.1021/acs.molpharmaceut.9b00014 · 2019 · External reference
Drug targeting to tumors: Principles, pitfalls and (pre-) clinical progress.
10.1016/j.jconrel.2011.09.063 · 2012 · External reference
Nanodelivery of nucleic acids.
10.1038/s43586-022-00104-y · 2022 · External reference
Engineering precision nanoparticles for drug delivery.
10.1038/s41573-020-0090-8 · 2021 · External reference
10.1007/978-1-59259-745-1_6
10.1007/978-1-59259-745-1_6 · 2004 · External reference
Association and Dissociation Characteristics of Polymer/DNA Complexes Used for Gene Delivery.
10.1023/a:1015096302720 · 1999 · External reference
Inflammation: a matter of immune cell life and death.
10.1038/s44385-025-00010-4 · 2025 · External reference
Use of Poly (ethylene glycol)–Lipid Conjugates to Regulate the Surface Attributes and Transfection Activity of Lipid–DNA Particles.
2000 · External reference
In vivo toxicity of cationic micelles and liposomes.
10.1016/j.nano.2014.08.004 · 2015 · External reference
Clinical experiences with systemically administered siRNA-based therapeutics in cancer.
10.1038/nrd4685 · 2015 · External reference
Modification of primary amines to higher order amines reduces in vivo hematological and immunotoxicity of cationic nanocarriers through TLR4 and complement pathways.
10.1016/j.biomaterials.2019.119512 · 2019 · External reference
The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect.
10.1016/j.addr.2010.04.009 · 2011 · External reference
A comparison of DNA compaction by arginine and lysine peptides: A physical basis for arginine rich protamines.
10.1021/bi4001408 · 2013 · External reference
Interaction of a Polyarginine Peptide with Membranes of Different Mechanical Properties.
10.3390/biom9100625 · 2019 · External reference
A catch-and-release nano-based gene delivery system.
10.1039/d3nh00269a · 2023 · External reference
Polydopamine-based nanoparticles with excellent biocompatibility for photothermally enhanced gene delivery.
10.1039/c8ra06916f · 2018 · External reference
Cation-free siRNA-cored nanocapsules for tumor-targeted RNAi therapy.
10.1016/j.actbio.2023.03.001 · 2023 · External reference
Modeling the proton sponge hypothesis: examining proton sponge effectiveness for enhancing intracellular gene delivery through multiscale modeling.
10.1080/09205063.2012.690282 · 2013 · External reference
Imidazolyl Lipids Enhanced LNP Endosomal Escape for Ferroptosis RNAi Treatment of Cancer.
10.1002/smll.202402362 · 2024 · External reference
Branching in poly (amine-co-ester) polyplexes impacts mRNA transfection.
10.1016/j.biomaterials.2024.122692 · 2024 · External reference
The study of relationships between pKa value and siRNA delivery efficiency based on tri-block copolymers.
10.1016/j.biomaterials.2018.05.046 · 2018 · External reference
Block catiomers with flanking hydrolyzable tyrosinate groups enhance in vivo mRNA delivery via π-π stacking-assisted micellar assembly.
10.1080/14686996.2023.2170164 · 2023 · External reference
Aromatic Modification of Low Molecular Weight PEI for Enhanced Gene Delivery.
10.3390/polym9080362 · 2017 · External reference
Guanidine-phosphate interactions stabilize polyion complex micelles based on flexible catiomers to improve mRNA delivery.
10.1016/j.eurpolymj.2020.110028 · 2020 · External reference
Intracellularly Disintegratable Polysulfoniums for Efficient Gene Delivery.
10.1002/adfm.201606826 · 2017 · External reference
Carbosilane dendrimers with phosphonium terminal groups are low toxic non-viral transfection vectors for siRNA cell delivery.
10.1016/j.ijpharm.2019.03.018 · 2019 · External reference
Cation Bulk and pKa Modulate Diblock Polymer Micelle Binding to pDNA.
10.1021/acsmacrolett.2c00015 · 2022 · External reference
Cationic Micelles Outperform Linear Polymers for Delivery of Antisense Oligonucleotides in Serum: An Exploration of Polymer Architecture, Cationic Moieties, and Cell Addition Order.
10.1021/acs.bioconjchem.2c00379 · 2022 · External reference
Polyphosphonium polymers for siRNA delivery: an efficient and nontoxic alternative to polyammonium carriers.
10.1021/ja207366k · 2012 · External reference
Alkylated Sulfonium Modification of Low Molecular Weight Polyethylenimine to Form Lipopolymers as Gene Vectors.
10.1021/acsomega.3c06255 · 2024 · External reference
Characterization of vectors for gene therapy formed by self-assembly of DNA with synthetic block co-polymers.
10.1089/hum.1996.7.17-2123 · 1996 · External reference
Gene delivery with low molecular weight linear polyethylenimines.
10.1002/jgm.775 · 2005 · External reference
Optimization of 25 kDa linear polyethylenimine for efficient gene delivery.
10.1016/j.biologicals.2006.08.004 · 2007 · External reference
Novel Bioreducible Poly (amido amine) s for Highly Efficient Gene Delivery.
10.1021/bc060200l · 2007 · External reference
Efficient transfer of genetic material into mammalian cells using Starburst polyamidoamine dendrimers.
10.1073/pnas.93.10.4897 · 1996 · External reference
Effects of the Physicochemical, Colloidal, and Biological Characteristics of Different Polymer Structures between α-Poly(l-lysine) and ε-Poly(l-lysine) on Polymeric Gene Delivery.
10.1021/acs.biomac.8b00097 · 2018 · External reference
Effective mRNA Protection by Poly(l-ornithine) Synergizes with Endosomal Escape Functionality of a Charge-Conversion Polymer toward Maximizing mRNA Introduction Efficiency.
10.1002/marc.202270036 · 2022 · External reference
Influence of polycation molecular weight on poly(2-dimethylaminoethyl methacrylate)-mediated DNA delivery in vitro.
10.1021/bm9000124 · 2009 · External reference
Semi-Automated Synthesis and Screening of a Large Library of Degradable Cationic Polymers for Gene Delivery.
10.1002/ange.200351244 · 2003 · External reference
Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo.
10.1002/jgm.187 · 2001 · External reference
Inhaled Nanoformulated mRNA Polyplexes for Protein Production in Lung Epithelium.
10.1002/adma.201805116 · 2019 · External reference
Branching in poly (amine-co-ester) polyplexes impacts mRNA transfection.
10.1016/j.biomaterials.2024.122692 · 2024 · External reference
Single cyclized molecule versus single branched molecule: a simple and efficient 3D ‘knot’ polymer structure for nonviral gene delivery.
10.1021/ja2105575 · 2012 · External reference
Cyclic poly(β-amino ester) s with enhanced gene transfection activity synthesized through intra-molecular cyclization.
10.1039/d1cc06480k · 2022 · External reference
3D Macrocyclic Structure Boosted Gene Delivery: Multi-Cyclic Poly(β-Amino Ester) s from Step Growth Polymerization.
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