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References from Mendelian randomisation identifies proteins with effects on multiple sclerosis and related traits. Local targets link to admitted publications; unresolved targets remain external evidence.
Rising prevalence of multiple sclerosis worldwide: Insights from the Atlas of MS, third edition.
10.1177/1352458520970841 · External reference
Proteomic analysis reveals dysregulation of peripheral blood neutrophils in patients with Multiple Sclerosis.
10.1093/cei/uxae115 · External reference
Diagnostic potential of blood-based biomarkers in multiple sclerosis.
10.3389/fneur.2024.1425046 · 2024 · External reference
Large-scale proteomics across neurological disorders uncovers biomarker panel and targets in multiple sclerosis.
10.1016/j.cell.2026.01.017 · External reference
Mendelian randomization identifies proteins involved in neurodegenerative diseases.
10.1093/brain/awaf018 · 2025 · External reference
The Barancik lecture: Comorbidity in multiple sclerosis—Looking backward, looking forward.
10.1177/13524585231167740 · 2023 · External reference
Neuropsychiatric Symptoms of Multiple Sclerosis: State of the Art.
10.30773/pi.2019.0106 · External reference
Influence of hypertension, diabetes, hyperlipidemia, and obstructive lung disease on multiple sclerosis disease course.
10.1177/1352458516650512 · External reference
Respiratory dysfunction in multiple sclerosis.
10.1016/j.rmed.2015.01.018 · External reference
Prevalence of asthma in multiple sclerosis: A United States population-based study.
10.1016/j.msard.2018.12.012 · External reference
Asthma and chronic obstructive pulmonary disease (COPD) in people with multiple sclerosis: A systematic review and meta-analysis.
10.1016/j.msard.2024.105546 · External reference
Polygenicity of Comorbid Depression in Multiple Sclerosis.
10.1212/wnl.0000000000207457 · External reference
Association of autoimmune comorbidities in persons with multiple sclerosis from a population-based study with genetic linkage.
10.1177/20552173251349671 · External reference
The MRC IEU OpenGWAS data infrastructure.
10.1101/2020.08.10.244293 · 2020 · External reference
Large-scale integration of the plasma proteome with genetics and disease.
10.1038/s41588-021-00978-w · External reference
Comorbidity in Multiple Sclerosis.
10.3389/fneur.2020.00851 · 2020 · External reference
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.
10.1038/s41593-018-0326-7 · External reference
FinnGen provides genetic insights from a well-phenotyped isolated population.
10.1038/s41586-022-05473-8 · External reference
Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank.
10.1038/s42003-021-02227-6 · External reference
The UK Biobank resource with deep phenotyping and genomic data.
10.1038/s41586-018-0579-z · External reference
Eliciting priors and relaxing the single causal variant assumption in colocalisation analyses.
10.1371/journal.pgen.1008720 · External reference
10.5281/zenodo.22771830
10.5281/zenodo.22771830 · 2026 · External reference
Strengthening the Reporting of Observational Studies in Epidemiology Using Mendelian Randomization: The STROBE-MR Statement.
10.1001/jama.2021.18236 · External reference
Data from: Underlying and extended data for "Mendelian randomisation identifies proteins with effects on multiple sclerosis and related traits".
10.5281/zenodo.22771511 · 2026 · External reference
Deficiency of the complement regulator CD59a enhances disease severity, demyelination and axonal injury in murine acute experimental allergic encephalomyelitis.
10.1038/labinvest.3700015 · External reference
Potential drug targets for multiple sclerosis identified through Mendelian randomization analysis.
10.1093/brain/awad070 · 2023 · External reference
The BHMT2/MAT1A/AHSG axis promotes M1 macrophage activation and exacerbates necrotizing enterocolitis.
10.1038/s41598-025-22915-1 · External reference
FCRL3 promotes TLR9-induced B-cell activation and suppresses plasma cell differentiation.
10.1002/eji.201243068 · External reference
Circulating Interleukins and Risk of Multiple Sclerosis: A Mendelian Randomization Study.
10.3389/fimmu.2021.647588 · 2021 · External reference
STATs in cancer inflammation and immunity: a leading role for STAT3.
10.1038/nrc2734 · External reference
T Helper Cells: The Modulators of Inflammation in Multiple Sclerosis.
10.3390/cells9020482 · External reference
MAPK signal pathways in the regulation of cell proliferation in mammalian cells.
10.1038/sj.cr.7290105 · External reference
Realigning the LIGHT signaling network to control dysregulated inflammation.
10.1084/jem.20220236 · External reference
Gene expression QTL mapping in stimulated iPSC-derived macrophages provides insights into common complex diseases.
10.1038/s41467-025-61670-9 · External reference
Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility.
10.1126/science.aav7188 · 2019 · External reference