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References from Stimulation of Host Bone Marrow Stromal Cells by Sympathetic Nerves Promotes Breast Cancer Bone Metastasis in Mice. Local targets link to admitted publications; unresolved targets remain external evidence.
The clinical course of bone metastases from breast cancer.
10.1038/bjc.1987.13 · 1987 · External reference
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Chemotherapy of breast cancer: a historical perspective.
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A multigenic program mediating breast cancer metastasis to bone.
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Cancer metastasis: building a framework.
10.1016/j.cell.2006.11.001 · 2006 · External reference
Fibroblasts isolated from common sites of breast cancer metastasis enhance cancer cell growth rates and invasiveness in an interleukin-6-dependent manner.
10.1158/0008-5472.can-08-0400 · 2008 · External reference
Differential effects of VEGFR-1 and VEGFR-2 inhibition on tumor metastases based on host organ environment.
10.1158/0008-5472.can-10-1138 · 2010 · External reference
Neuronal signaling and the regulation of bone remodeling.
10.1007/s00018-005-5175-3 · 2005 · External reference
Leptin regulates bone formation via the sympathetic nervous system.
10.1016/s0092-8674(02)01049-8 · 2002 · External reference
Characterization of beta-adrenergic receptors on rat and human osteoblast-like cells and demonstration that beta-receptor agonists can stimulate bone resorption in organ culture.
10.1016/s0169-6009(08)80105-5 · 1993 · External reference
Expression of mRNAs for neuropeptide receptors and beta-adrenergic receptors in human osteoblasts and human osteogenic sarcoma cells.
10.1016/s0304-3940(97)00649-6 · 1997 · External reference
Formoterol and isoproterenol induce c-fos gene expression in osteoblast-like cells by activating beta2-adrenergic receptors.
10.1016/s8756-3282(98)00026-x · 1998 · External reference
Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow.
10.1016/j.cell.2005.10.041 · 2006 · External reference
Osteoblastic activation in the hematopoietic stem cell niche.
10.1196/annals.1346.021 · 2006 · External reference
Haematopoietic stem cell release is regulated by circadian oscillations.
10.1038/nature06685 · 2008 · External reference
Cooperation of beta(2)- and beta(3)-adrenergic receptors in hematopoietic progenitor cell mobilization.
10.1111/j.1749-6632.2010.05390.x · 2010 · External reference
Physiology: do neural signals remodel bone?
10.1038/434447a · 2005 · External reference
Leptin regulation of bone resorption by the sympathetic nervous system and CART.
10.1038/nature03398 · 2005 · External reference
Stressful life experiences and risk of relapse of breast cancer: observational cohort study.
10.1136/bmj.324.7351.1420 · 2002 · External reference
Do stress-related psychosocial factors contribute to cancer incidence and survival?
10.1038/ncponc1134 · 2008 · External reference
Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma.
10.1038/nm1447 · 2006 · External reference
The sympathetic nervous system induces a metastatic switch in primary breast cancer.
10.1158/0008-5472.can-10-0522 · 2010 · External reference
Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis.
10.1172/jci118947 · 1996 · External reference
Inhibition of osteolytic bone metastasis of breast cancer by combined treatment with the bisphosphonate ibandronate and tissue inhibitor of the matrix metalloproteinase-2.
10.1172/jci119435 · 1997 · External reference
Osteoactivin promotes breast cancer metastasis to bone.
10.1158/1541-7786.mcr-07-0119 · 2007 · External reference
The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development.
10.1016/s0092-8674(00)00103-3 · 2000 · External reference
Regulation of cancer cell migration and bone metastasis by RANKL.
10.1038/nature04524 · 2006 · External reference
Expression pattern of receptor activator of NFkappaB (RANK) in a series of primary solid tumors and related bone metastases.
10.1002/jcp.22402 · 2011 · External reference
Stress hormone-mediated invasion of ovarian cancer cells.
10.1158/1078-0432.ccr-05-1698 · 2006 · External reference
Epinephrine protects cancer cells from apoptosis via activation of cAMP-dependent protein kinase and BAD phosphorylation.
10.1074/jbc.m611370200 · 2007 · External reference
A bone-seeking clone exhibits different biological properties from the MDA-MB-231 parental human breast cancer cells and a brain-seeking clone in vivo and in vitro.
10.1359/jbmr.2001.16.8.1486 · 2001 · External reference
Genetic determination of the cellular basis of the sympathetic regulation of bone mass accrual.
10.1084/jem.20102608 · 2011 · External reference
Bone: Osteocyte RANKL in bone homeostasis: a paradigm shift?
10.1038/nrrheum.2011.151 · 2011 · External reference
beta2-Adrenergic receptor signaling in osteoblasts contributes to the catabolic effect of glucocorticoids on bone.
10.1210/en.2010-0881 · 2011 · External reference
Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma.
10.1038/nm1447 · 2006 · External reference
Norepinephrine upregulates VEGF, IL-8, and IL-6 expression in human melanoma tumor cell lines: implications for stress-related enhancement of tumor progression.
10.1016/j.bbi.2008.10.005 · 2009 · External reference
Norepinephrine up-regulates the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumor cells.
10.1158/0008-5472.can-06-2496 · 2006 · External reference
Inhibition of RANKL blocks skeletal tumor progression and improves survival in a mouse model of breast cancer bone metastasis.
10.1007/s10585-007-9127-1 · 2008 · External reference
Randomized trial of denosumab in patients receiving adjuvant aromatase inhibitors for nonmetastatic breast cancer.
10.1200/jco.2008.16.3832 · 2008 · External reference
[Anti-RANKL antibody for the management of bone metastasis].
2011 · External reference
Receptor activator for nuclear factor kappa B expression predicts poor prognosis in breast cancer patients with bone metastasis but not in patients with visceral metastasis.
10.1136/jclinpath-2011-200312 · 2012 · External reference
Beta-blocker drug therapy reduces secondary cancer formation in breast cancer and improves cancer specific survival.
10.18632/oncotarget.197 · 2010 · External reference
Beta-blocker use is associated with improved relapse-free survival in patients with triple-negative breast cancer.
10.1200/jco.2010.33.4441 · 2011 · External reference
Beta blockers and breast cancer mortality: a population- based study.
10.1200/jco.2010.33.5422 · 2011 · External reference
Denosumab and bone-metastasis-free survival in men with castration-resistant prostate cancer: results of a phase 3, randomised, placebo-controlled trial.
10.1016/s0140-6736(11)61226-9 · 2012 · External reference
Propranolol potentiates the anti-angiogenic effects and anti-tumor efficacy of chemotherapy agents: implication in breast cancer treatment.
10.18632/oncotarget.343 · 2011 · External reference
