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References from Reduced serotonergic transmission alters sensitivity to cost and reward via 5-HT1A and 5-HT1B receptors in monkeys. Local targets link to admitted publications; unresolved targets remain external evidence.
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2016 · External reference
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10.1007/pl00005485 · 1999 · External reference
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Effects of central 5-hydroxytryptamine depletion on sensitivity to delayed and probabilistic reinforcement
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Low-serotonin levels increase delayed reward discounting in humans
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Does the effect of central 5-hydroxytryptamine depletion on timing depend on motivational change?
10.1007/bf02247367 · 1993 · External reference
Effect of lesions of the ascending 5-hydroxytryptaminergic pathways on choice between delayed reinforcers
10.1007/bf02245530 · 1993 · External reference
The effect of 5-HT(1A) receptor antagonist on reward-based decision-making
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Activation of dorsal raphe serotonin neurons is necessary for waiting for delayed rewards
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International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function
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D1- and D2-like receptors differentially mediate the effects of dopaminergic transmission on cost-benefit evaluation and motivation in monkeys
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A High-Resolution In Vivo Atlas of the Human Brain’s Serotonin System
2017 · External reference
Neural signals in the monkey ventral striatum related to motivation for juice and cocaine rewards
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Is working more costly than waiting in monkeys?
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Hydration level is an internal variable for computing motivation to obtain water rewards in monkeys
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Tryptophan depletion disrupts the motivational guidance of goal-directed behavior as a function of trait impulsivity
10.1038/sj.npp.1300704 · 2005 · External reference
Serotonin transporter polymorphism mediates vulnerability to loss of incentive motivation following acute tryptophan depletion
10.1038/sj.npp.1301055 · 2006 · External reference
Simplified reference tissue model for PET receptor studies
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Fractionating impulsivity: contrasting effects of central 5-HT depletion on different measures of impulsive behavior
10.1038/sj.npp.1300434 · 2004 · External reference
Serotonin and dopamine: unifying affective, activational, and decision functions
10.1038/npp.2010.121 · 2011 · External reference
Dual serotonergic signals: a key to understanding paradoxical effects?
2014 · External reference
Modulation of dopamine release in the nucleus accumbens by 5-HT1B agonists: involvement of the hippocampo-accumbens pathway
10.1016/s0028-3908(96)00099-8 · 1996 · External reference
Involvement of 5-HT1B receptors within the ventral tegmental area in regulation of mesolimbic dopaminergic neuronal activity via GABA mechanisms: a study with dual-probe microdialysis
10.1016/j.brainres.2004.06.053 · 2004 · External reference
Effects of serotonin (5-HT)(1B) receptor ligands on cocaine-seeking behavior in rats
2008 · External reference
Enriched expression of serotonin 1B and 2A receptor genes in macaque visual cortex and their bidirectional modulatory effects on neuronal responses
10.1093/cercor/bhn219 · 2009 · External reference
Cholinergic and serotonergic modulation of visual information processing in monkey V1
10.1016/j.jphysparis.2016.09.001 · 2016 · External reference
A role for reward valuation in the serotonergic modulation of impulsivity
10.1007/s00213-021-05944-2 · 2021 · External reference
A possible mechanism of the nucleus accumbens and ventral pallidum 5-HT1B receptors underlying the antidepressant action of ketamine: a PET study with macaques
10.1038/tp.2013.112 · 2014 · External reference
Neuroimaging of reward mechanisms in Gambling disorder: an integrative review
10.1038/s41380-018-0230-2 · 2019 · External reference
Serotonin 1B receptor imaging in alcohol dependence
10.1016/j.biopsych.2009.12.028 · 2010 · External reference
Synaptic mechanism underlying serotonin modulation of transition to cocaine addiction
10.1126/science.abi9086 · 2021 · External reference
Reductions in brain 5-HT1B receptor availability in primarily cocaine-dependent humans
10.1016/j.biopsych.2013.11.022 · 2014 · External reference
Linking in vivo brain serotonin type 1B receptor density to phenotypic heterogeneity of posttraumatic stress symptomatology
10.1038/mp.2012.60 · 2013 · External reference
The effects of acute tryptophan depletion on costly information sampling: impulsivity or aversive processing?
10.1007/s00213-011-2577-9 · 2012 · External reference
Serotonin and decision making processes
10.1016/j.neubiorev.2011.06.001 · 2012 · External reference
Varieties of impulsivity
10.1007/pl00005481 · 1999 · External reference
The pharmacology of impulsive behaviour in rats VI: the effects of ethanol and selective serotonergic drugs on response choice with varying delays of reinforcement
10.1007/pl00005486 · 1999 · External reference
Role of medial prefrontal and orbitofrontal monoamine transporters and receptors in performance in an adjusting delay discounting procedure
10.1016/j.brainres.2014.06.004 · 2014 · External reference
Effects of lisdexamfetamine and s-citalopram, alone and in combination, on effort-related choice behavior in the rat
10.1007/s00213-015-4176-7 · 2016 · External reference
Sex differences in lever pressing and running wheel tasks of effort-based choice behavior in rats: Suppression of high effort activity by the serotonin transport inhibitor fluoxetine
10.1016/j.pbb.2021.173115 · 2021 · External reference
Impaired reward learning and intact motivation after serotonin depletion in rats
10.1016/j.bbr.2012.05.032 · 2012 · External reference
Resolution of sleepiness and fatigue in major depressive disorder: A comparison of bupropion and the selective serotonin reuptake inhibitors
10.1016/j.biopsych.2006.06.015 · 2006 · External reference
Clinical relevance of fatigue as a residual symptom in major depressive disorder
10.1002/da.22199 · 2014 · External reference
Resolution of sleepiness and fatigue: a comparison of bupropion and selective serotonin reuptake inhibitors in subjects with major depressive disorder achieving remission at doses approved in the European Union
10.1177/0269881113514878 · 2014 · External reference
The relationship between change in apathy and changes in cognition and functional outcomes in currently non-depressed SSRI-treated patients with major depressive disorder
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Cognitive tolerability following successful long term treatment of major depression and anxiety disorders with SSRi antidepressants
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Serotonin type-1A receptor imaging in depression
10.1016/s0969-8051(00)00119-0 · 2000 · External reference
Decreased brain serotonin 5-HT1A receptor availability in medication-naive patients with major depressive disorder: an in-vivo imaging study using PET and [carbonyl-11C]WAY-100635
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Behavioral depression and positron emission tomography-determined serotonin 1A receptor binding potential in cynomolgus monkeys
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Dissociable contribution of 5-HT1A and 5-HT2A receptors in the medial prefrontal cortex to different aspects of executive control such as impulsivity and compulsive perseveration in rats
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A comparison of multiple 5-HT receptors in two tasks measuring impulsivity
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Global 5-HT depletion attenuates the ability of amphetamine to decrease impulsive choice on a delay-discounting task in rats
10.1007/s00213-003-1546-3 · 2003 · External reference
An Interaction between Serotonin Receptor Signaling and Dopamine Enhances Goal-Directed Vigor and Persistence in Mice
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Serotonergic neurons signal reward and punishment on multiple timescales
2015 · External reference
Single-cell activity and network properties of dorsal raphe nucleus serotonin neurons during emotionally salient behaviors
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Computational Mechanisms of Effort and Reward Decisions in Patients With Depression and Their Association With Relapse After Antidepressant Discontinuation
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Differences between males and females in rates of serotonin synthesis in human brain
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The mouse 5-hydroxytryptamine1B receptor is localized predominantly on axon terminals
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