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References from Unveiling recent and ongoing adaptive selection in human populations. Local targets link to admitted publications; unresolved targets remain external evidence.
A map of recent positive selection in the human genome
10.1371/journal.pbio.0040072 · 2006 · External reference
Identifying genetic variants that affect viability in large cohorts
10.1371/journal.pbio.2002458 · 2017 · External reference
A population genetic interpretation of GWAS findings for human quantitative traits
10.1371/journal.pbio.2002985 · 2018 · External reference
Polygenic signals of sex differences in selection in humans from the UK Biobank
10.1371/journal.pbio.3001768 · 2022 · External reference
Estimating the selective effects of heterozygous protein-truncating variants from human exome data
10.1038/ng.3831 · 2017 · External reference
The mutational constraint spectrum quantified from variation in 141,456 humans
10.1038/s41586-020-2308-7 · 2020 · External reference
Reduced reproductive success is associated with selective constraint on human genes
10.1038/s41586-022-04549-9 · 2022 · External reference
A genome-wide mutational constraint map quantified from variation in 76,156 human genomes
2022 · External reference
Recent and ongoing selection in the human genome
10.1038/nrg2187 · 2007 · External reference
Scanning the human genome for “signatures” of positive selection: Transformative opportunities and ethical obligations
10.1002/evan.21893 · 2021 · External reference
Going global by adapting local: A review of recent human adaptation
10.1126/science.aaf5098 · 2016 · External reference
Searching for footprints of positive selection in whole-genome SNP data from nonequilibrium populations
10.1534/genetics.110.116459 · 2010 · External reference
Distinguishing between selective sweeps from standing variation and from a de novo mutation
10.1371/journal.pgen.1003011 · 2012 · External reference
Supervised Machine Learning for Population Genetics: A New Paradigm
10.1016/j.tig.2017.12.005 · 2018 · External reference
Detection of human adaptation during the past 2000 years
10.1126/science.aag0776 · 2016 · External reference
High-throughput inference of pairwise coalescence times identifies signals of selection and enriched disease heritability
10.1038/s41588-018-0177-x · 2018 · External reference
Identity-by-descent detection across 487,409 British samples reveals fine scale population structure and ultra-rare variant associations
10.1038/s41467-020-19588-x · 2020 · External reference
From Summary Statistics to Gene Trees: Methods for Inferring Positive Selection
10.1016/j.tig.2019.12.008 · 2020 · External reference
A method for genome-wide genealogy estimation for thousands of samples
10.1038/s41588-019-0484-x · 2019 · External reference
An approximate full-likelihood method for inferring selection and allele frequency trajectories from DNA sequence data
10.1371/journal.pgen.1008384 · 2019 · External reference
Ancient Genomics of Modern Humans: The First Decade
10.1146/annurev-genom-083117-021749 · 2018 · External reference
Inference of natural selection from ancient DNA
10.1002/evl3.165 · 2020 · External reference
Harnessing ancient genomes to study the history of human adaptation
10.1038/nrg.2017.65 · 2017 · External reference
Admixture has obscured signals of historical hard sweeps in humans
10.1038/s41559-022-01914-9 · 2022 · External reference
Adaptive evolution of the FADS gene cluster within Africa
10.1371/journal.pone.0044926 · 2012 · External reference
Genome-wide patterns of selection in 230 ancient Eurasians
10.1038/nature16152 · 2015 · External reference
Greenlandic Inuit show genetic signatures of diet and climate adaptation
10.1126/science.aab2319 · 2015 · External reference
Selection in Europeans on Fatty Acid Desaturases Associated with Dietary Changes
10.1093/molbev/msx103 · 2017 · External reference
FADS1 and the Timing of Human Adaptation to Agriculture
10.1093/molbev/msy180 · 2018 · External reference
Limited Evidence for Selection at the FADS Locus in Native American Populations
10.1093/molbev/msaa064 · 2020 · External reference
Population genomics of Bronze Age Eurasia
10.1038/nature14507 · 2015 · External reference
Massive migration from the steppe was a source for Indo-European languages in Europe
10.1038/nature14317 · 2015 · External reference
The evolution of skin pigmentation-associated variation in West Eurasia
2021 · External reference
Hunter-gatherer admixture facilitated natural selection in Neolithic European farmers
10.1016/j.cub.2023.02.049 · 2023 · External reference
1,000 ancient genomes uncover 10,000 years of natural selection in Europe
2022 · External reference
Rapid adaptation to malaria facilitated by admixture in the human population of Cabo Verde
2021 · External reference
Admixture-enabled selection for rapid adaptive evolution in the Americas
10.1186/s13059-020-1946-2 · 2020 · External reference
The origins of lactase persistence in Europe
10.1371/journal.pcbi.1000491 · 2009 · External reference
Direct detection of natural selection in Bronze Age Britain
10.1101/gr.276862.122 · 2022 · External reference
Direct evidence for positive selection of skin, hair, and eye pigmentation in Europeans during the last 5,000 y
10.1073/pnas.1316513111 · 2014 · External reference
Evolution of immune genes is associated with the Black Death
10.1038/s41586-022-05349-x · 2022 · External reference
Insufficient evidence for natural selection associated with the Black Death
2023 · External reference
The population genomic legacy of the second plague pandemic
10.1016/j.cub.2022.09.023 · 2022 · External reference
Medieval social landscape through the genetic history of Cambridgeshire before and after the Black Death
2023 · External reference
Natural selection and the heritability of fitness components
10.1038/hdy.1987.113 · 1987 · External reference
Physical and neurobehavioral determinants of reproductive onset and success
10.1038/ng.3551 · 2016 · External reference
Genome-wide analysis identifies 12 loci influencing human reproductive behavior
10.1038/ng.3698 · 2016 · External reference
Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus
10.1038/s41562-023-01528-6 · 2023 · External reference
Dietary adaptation of FADS genes in Europe varied across time and geography
10.1038/s41559-017-0167 · 2017 · External reference
Detecting Long-Term Balancing Selection Using Allele Frequency Correlation
10.1093/molbev/msx209 · 2017 · External reference
Signatures of Long-Term Balancing Selection in Human Genomes
10.1093/gbe/evy054 · 2018 · External reference
GWAS on birth year infant mortality rates provides evidence of recent natural selection
10.1073/pnas.2117312119 · 2022 · External reference
Evolutionary demographic models reveal the strength of purifying selection on susceptibility alleles to late-onset diseases
10.1038/s41559-020-01355-2 · 2021 · External reference
Natural selection on genes that underlie human disease susceptibility
10.1016/j.cub.2008.04.074 · 2008 · External reference
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer’s disease in late onset families
10.1126/science.8346443 · 1993 · External reference
The quest for genetic determinants of human longevity: challenges and insights
10.1038/nrg1871 · 2006 · External reference
Genome-wide meta-analyses identify multiple loci associated with smoking behavior
10.1038/ng.571 · 2010 · External reference
Detection of Allelic Frequency Differences between the Sexes in Humans: A Signature of Sexually Antagonistic Selection
10.1093/gbe/evw090 · 2016 · External reference
Evaluating human autosomal loci for sexually antagonistic viability selection in two large biobanks
10.1093/genetics/iyaa015 · 2021 · External reference
An unbiased test reveals no enrichment of sexually antagonistic polymorphisms on the human X chromosome
2022 · External reference
Limits to Genomic Divergence Under Sexually Antagonistic Selection
10.1534/g3.119.400711 · 2019 · External reference
Sex-Specific Selection and Sex-Biased Gene Expression in Humans and Flies
10.1371/journal.pgen.1006170 · 2016 · External reference
Genetic signatures of strong recent positive selection at the lactase gene
10.1086/421051 · 2004 · External reference
The challenge of detecting recent natural selection in human populations
10.1073/pnas.2203237119 · 2022 · External reference
Genetic analyses identify widespread sex-differential participation bias
10.1038/s41588-021-00846-7 · 2021 · External reference
Comparison of Sociodemographic and Health-Related Characteristics of UK Biobank Participants With Those of the General Population
10.1093/aje/kwx246 · 2017 · External reference
The correlation between relatives on the supposition of mendelian inheritance
1918 · External reference
The genetics of human adaptation: hard sweeps, soft sweeps, and polygenic adaptation
10.1016/j.cub.2009.11.055 · 2010 · External reference
Variants associated with common disease are not unusually differentiated in frequency across populations
10.1086/499287 · 2006 · External reference
Evidence of widespread selection on standing variation in Europe at height-associated SNPs
10.1038/ng.2368 · 2012 · External reference
Population genetic differentiation of height and body mass index across Europe
10.1038/ng.3401 · 2015 · External reference
Height-reducing variants and selection for short stature in Sardinia
10.1038/ng.3403 · 2015 · External reference
A population genetic signal of polygenic adaptation
10.1371/journal.pgen.1004412 · 2014 · External reference
Detecting Polygenic Adaptation in Admixture Graphs
10.1534/genetics.117.300489 · 2018 · External reference
Reconstructing the History of Polygenic Scores Using Coalescent Trees
10.1534/genetics.118.301687 · 2019 · External reference
Disentangling selection on genetically correlated polygenic traits via whole-genome genealogies
10.1016/j.ajhg.2020.12.005 · 2021 · External reference
Measuring selection in contemporary human populations
10.1038/nrg2831 · 2010 · External reference
Genetic evidence for natural selection in humans in the contemporary United States
10.1073/pnas.1600398113 · 2016 · External reference
Selection against variants in the genome associated with educational attainment
10.1073/pnas.1612113114 · 2017 · External reference
Human fertility, molecular genetics, and natural selection in modern societies
10.1371/journal.pone.0126821 · 2015 · External reference
Evidence of directional and stabilizing selection in contemporary humans
10.1073/pnas.1707227114 · 2018 · External reference
Amplification is the primary mode of gene-by-sex interaction in complex human traits
10.1016/j.xgen.2023.100297 · 2023 · External reference
Sex-specific associations of circulating testosterone levels with all-cause and cause-specific mortality
10.1530/eje-20-1253 · 2021 · External reference
Tread Lightly Interpreting Polygenic Tests of Selection
10.1534/genetics.118.300786 · 2018 · External reference
Reduced signal for polygenic adaptation of height in UK Biobank
2019 · External reference
Polygenic adaptation on height is overestimated due to uncorrected stratification in genome-wide association studies
2019 · External reference
Human Demographic History Impacts Genetic Risk Prediction across Diverse Populations
10.1016/j.ajhg.2017.03.004 · 2017 · External reference
Variable prediction accuracy of polygenic scores within an ancestry group
2020 · External reference
Demographic history mediates the effect of stratification on polygenic scores
2020 · External reference
Functional architecture of low-frequency variants highlights strength of negative selection across coding and non-coding annotations
10.1038/s41588-018-0231-8 · 2018 · External reference
Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection
10.1038/s41467-019-08424-6 · 2019 · External reference
Signatures of negative selection in the genetic architecture of human complex traits
10.1038/s41588-018-0101-4 · 2018 · External reference
The genetic variability of polygenic characters under optimizing selection, mutation and drift
10.1017/s0016672300014221 · 1972 · External reference
The evolution of group differences in changing environments
10.1371/journal.pbio.3001072 · 2021 · External reference
Population differentiation of polygenic score predictions under stabilizing selection
10.1098/rstb.2020.0416 · 2022 · External reference
The Measurement of Selection on Correlated Characters
10.2307/2408842 · 1983 · External reference
An atlas of genetic correlations across human diseases and traits
10.1038/ng.3406 · 2015 · External reference
HOPS: a quantitative score reveals pervasive horizontal pleiotropy in human genetic variation is driven by extreme polygenicity of human traits and diseases
10.1186/s13059-019-1844-7 · 2019 · External reference
How well do we understand the basis of classic selective sweeps in humans?
10.1002/1873-3468.13447 · 2019 · External reference
One hundred years of pleiotropy: a retrospective
10.1534/genetics.110.122549 · 2010 · External reference
Human adaptation over the past 40,000 years
10.1016/j.gde.2020.06.003 · 2020 · External reference
Maintenance of Complex Trait Variation: Classic Theory and Modern Data
10.3389/fgene.2021.763363 · 2021 · External reference
