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References from Chemical modulation of gut bacterial metabolism induces colanic acid and extends the lifespan of nematode and mammalian hosts. Local targets link to admitted publications; unresolved targets remain external evidence.
The impact of the gut microbiota on human health: an integrative view
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The gut microbiota-brain axis in behaviour and brain disorders
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Interaction between microbiota and immunity in health and disease
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The gut microbiome as a modulator of healthy ageing
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An expanded reference map of the human gut microbiome reveals hundreds of previously unknown species
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Host and microbiota metabolic signals in aging and longevity
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Beyond butyrate: microbial fiber metabolism supporting colonic epithelial homeostasis
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Tryptophan metabolism: a link between the gut microbiota and brain
10.1093/advances/nmz127 · 2020 · External reference
The impact of diet and lifestyle on gut microbiota and human health
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The influence of gut microbiota on drug metabolism and toxicity
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Chemical transformation of xenobiotics by the human gut microbiota
10.1126/science.aag2770 · 2017 · External reference
Bidirectional interactions between indomethacin and the murine intestinal microbiota
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IL-22 alters gut microbiota composition and function to increase aryl hydrocarbon receptor activity in mice and humans
10.1186/s40168-023-01486-1 · 2023 · External reference
Proton pump inhibitors alter the composition of the gut microbiota
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Impact of commonly used drugs on the composition and metabolic function of the gut microbiota
10.1038/s41467-019-14177-z · 2020 · External reference
Microbiome-based therapeutics
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Structural studies on colanic acid, the common exopolysaccharide found in the enterobacteriaceae, by partial acid hydrolysis. Oligosaccharides from colanic acid
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Regulation of capsular polysaccharide synthesis in Escherichia coli K-12: characterization of three regulatory genes
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Microbial genetic composition tunes host longevity
10.1016/j.cell.2017.05.036 · 2017 · External reference
Optogenetic control of gut bacterial metabolism to promote longevity
10.7554/elife.56849 · 2020 · External reference
A unified catalog of 204,938 reference genomes from the human gut microbiome
10.1038/s41587-020-0603-3 · 2021 · External reference
Sensitive protein alignments at tree-of-life scale using DIAMOND
10.1038/s41592-021-01101-x · 2021 · External reference
Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians
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A cross-sectional study of compositional and functional profiles of gut microbiota in sardinian centenarians
2019 · External reference
Enterobacteriaceae in the human gut: dynamics and ecological roles in health and disease
2024 · External reference
Escherichia coli residency in the gut of healthy human adults
2020 · External reference
Temperature has reciprocal effects on colanic acid and polysialic acid biosynthesis in E. coli K92
10.1007/s00253-008-1840-4 · 2009 · External reference
beta-Lactam induction of colanic acid gene expression in Escherichia coli
10.1016/s0378-1097(03)00616-5 · 2003 · External reference
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1992 · External reference
Restricted intestinal absorption of some beta-lactam antibiotics by an energy-dependent efflux system in rat intestine
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Gastrointestinal transit measurements in mice with 99mTc-DTPA-labeled activated charcoal using NanoSPECT-CT
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The outer mucus layer hosts a distinct intestinal microbial niche
10.1038/ncomms9292 · 2015 · External reference
Distinct penicillin binding proteins involved in the division, elongation, and shape of Escherichia coli K12
10.1073/pnas.72.8.2999 · 1975 · External reference
Profiling of β-lactam selectivity for penicillin-binding proteins in Escherichia coli strain DC2
10.1128/aac.04552-14 · 2015 · External reference
Murein synthesis and beta-lactam antibiotic susceptibility during rod-to-sphere transition in a pbpA(Ts) mutant of Escherichia coli
10.1128/aac.19.5.891 · 1981 · External reference
AmpC beta-lactamases
10.1128/cmr.00036-08 · 2009 · External reference
The E. coli β-lactamase attenuator mediates growth rate-dependent regulation
10.1038/290221a0 · 1981 · External reference
The two-component system ZraPSR is a novel ESR that contributes to intrinsic antibiotic tolerance in Escherichia coli
10.1016/j.jmb.2018.10.021 · 2018 · External reference
Microbial metabolites regulate host lipid metabolism through NR5A-Hedgehog signalling
10.1038/ncb3515 · 2017 · External reference
The DNA of Caenorhabditis elegans
10.1093/genetics/77.1.95 · 1974 · External reference
Aging. Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans
10.1126/science.1258857 · 2015 · External reference
Measuring mRNA copy number in individual Escherichia coli cells using single-molecule fluorescent in situ hybridization
10.1038/nprot.2013.066 · 2013 · External reference
Imaging the in vivo growth patterns of bacteria in human gut Microbiota
10.1080/19490976.2021.1960134 · 2021 · External reference
Antibiotic susceptibility determination within one cell cycle at single-bacterium level by stimulated raman metabolic imaging
10.1021/acs.analchem.7b03382 · 2018 · External reference
Label-free imaging of lipid storage dynamics in Caenorhabditis elegans using stimulated Raman scattering microscopy
2021 · External reference
RNAsnap™: a rapid, quantitative and inexpensive, method for isolating total RNA from bacteria
10.1093/nar/gks680 · 2012 · External reference
GFF utilities: GffRead and GffCompare
10.12688/f1000research.23297.1 · 2020 · External reference
Organization of the Escherichia coli K-12 gene cluster responsible for production of the extracellular polysaccharide colanic acid
10.1128/jb.178.16.4885-4893.1996 · 1996 · External reference
MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transform
10.1093/nar/gkf436 · 2002 · External reference
trimAl: a tool for automated alignment trimming in large-scale phylogenetic analyses
10.1093/bioinformatics/btp348 · 2009 · External reference
SeqKit: a cross-platform and ultrafast toolkit for FASTA/Q file manipulation
10.1371/journal.pone.0163962 · 2016 · External reference
IQ-TREE 2: new models and efficient methods for phylogenetic inference in the genomic era
10.1093/molbev/msaa015 · 2020 · External reference
ggtreeExtra: compact visualization of richly annotated phylogenetic data
10.1093/molbev/msab166 · 2021 · External reference
Twelve years of SAMtools and BCFtools
10.1093/gigascience/giab008 · 2021 · External reference
Extending and improving metagenomic taxonomic profiling with uncharacterized species using MetaPhlAn 4
10.1038/s41587-023-01688-w · 2023 · External reference
phyloseq: an R package for reproducible interactive analysis and graphics of microbiome census data
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