Research graph
References from Experience-dependent serotonergic signaling in glia regulates targeted synapse elimination. Local targets link to admitted publications; unresolved targets remain external evidence.
Critical period plasticity in local cortical circuits
10.1038/nrn1787 · 2005 · External reference
Silent Synapse-Based Mechanisms of Critical Period Plasticity.
10.3389/fncel.2020.00213 · 2020 · External reference
The period of susceptibility to the physiological effects of unilateral eye closure in kittens
10.1113/jphysiol.1970.sp009022 · 1970 · External reference
Critical period regulation across multiple timescales
10.1073/pnas.1820836117 · 2020 · External reference
Balancing plasticity/stability across brain development
10.1016/b978-0-444-63327-9.00001-1 · 2013 · External reference
Shifting Developmental Trajectories During Critical Periods of Brain Formation.
10.3389/fncel.2020.00283 · 2020 · External reference
Cell Biology of Astrocyte-Synapse Interactions.
10.1016/j.neuron.2017.09.056 · 2017 · External reference
Neuron-Glia Signaling in Synapse Elimination
10.1146/annurev-neuro-070918-050306 · 2019 · External reference
Phagocytic Glial Cells in Brain Homeostasis.
2021 · External reference
Microglial Interactions with Synapses Are Modulated by Visual Experience.
10.1371/journal.pbio.1000527 · 2010 · External reference
Experience-dependent glial pruning of synaptic glomeruli during the critical period.
10.1038/s41598-024-59942-3 · 2024 · External reference
Early Draper-mediated glial refinement of neuropil architecture and synapse number in the Drosophila antennal lobe
2023 · External reference
Environmental influences on the pace of brain development
10.1038/s41583-021-00457-5 · 2021 · External reference
Mechanisms governing activity-dependent synaptic pruning in the developing mammalian CNS.
10.1038/s41583-021-00507-y · 2021 · External reference
A Novel Phagocytic Role of Astrocytes in Activity-dependent Elimination of Mature Excitatory Synapses.
10.1007/s12264-021-00690-z · 2021 · External reference
Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways.
10.1038/nature12776 · 2013 · External reference
Astrocytes and microglia play orchestrated roles and respect phagocytic territories during neuronal corpse removal in vivo
2020 · External reference
Astrocytes engage unique molecular programs to engulf pruned neuronal debris from distinct subsets of neurons
10.1101/gad.229518.113 · 2014 · External reference
Synaptic Plasticity: Multiple Forms, Functions, and Mechanisms
10.1038/sj.npp.1301559 · 2008 · External reference
Astrocytes close a motor circuit critical period
10.1038/s41586-021-03441-2 · 2021 · External reference
5-HT-dependent synaptic plasticity of the prefrontal cortex in postnatal development
2022 · External reference
Serotonin in the Modulation of Neural Plasticity and Networks: Implications for Neurodevelopmental Disorders
10.1016/j.neuron.2012.09.013 · 2012 · External reference
Molecular Evolution of Tryptophan Hydroxylases in Vertebrates: A Comparative Genomic Survey.
2019 · External reference
Identified Serotonergic Modulatory Neurons Have Heterogeneous Synaptic Connectivity within the Olfactory System of Drosophila
10.1523/jneurosci.0192-17.2017 · 2017 · External reference
The Wiring Logic of an Identified Serotonergic Neuron That Spans Sensory Networks
10.1523/jneurosci.0552-20.2020 · 2020 · External reference
Serotonergic Signaling Controls Input-Specific Synaptic Plasticity at Striatal Circuits
10.1016/j.neuron.2018.04.008 · 2018 · External reference
Past experience shapes sexually dimorphic neuronal wiring through monoaminergic signalling
10.1038/s41586-018-0452-0 · 2018 · External reference
Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets.
2023 · External reference
Dysfunctional serotonergic neuron-astrocyte signaling in depressive-like states
2023 · External reference
Serotonin stimulates secretion of exosomes from microglia cells
10.1002/glia.22772 · 2015 · External reference
Serotonin receptor 4 regulates hippocampal astrocyte morphology and function
10.1002/glia.23933 · 2021 · External reference
The role of serotonin 5-HT2A receptors in memory and cognition.
10.3389/fphar.2015.00225 · 2015 · External reference
Sustained Activation of Postsynaptic 5-HT2A Receptors Gates Plasticity at Prefrontal Cortex Synapses
10.1093/cercor/bhy064 · 2019 · External reference
Serotonin Modulates Developmental Microglia via 5-HT2B Receptors: Potential Implication during Synaptic Refinement of Retinogeniculate Projections.
10.1021/cn5003489 · 2015 · External reference
Serotonin Receptors as Therapeutic Targets for Autism Spectrum Disorder Treatment.
2022 · External reference
PTSD: from neurobiology to pharmacological treatments.
10.3402/ejpt.v7.31858 · 2016 · External reference
Serotonin-related rodent models of early-life exposure relevant for neurodevelopmental vulnerability to psychiatric disorders.
10.1038/s41398-021-01388-6 · 2021 · External reference
Early life adversity shapes neural circuit function during sensitive postnatal developmental periods.
10.1038/s41398-022-02092-9 · 2022 · External reference
Psychedelics Promote Structural and Functional Neural Plasticity
10.1016/j.celrep.2018.05.022 · 2018 · External reference
Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors
10.1126/science.adf0435 · 2023 · External reference
Rejuvenation of plasticity in the brain: opening the critical period
10.1016/j.conb.2018.09.003 · 2019 · External reference
Psychedelics reopen the social reward learning critical period
10.1038/s41586-023-06204-3 · 2023 · External reference
Towards an understanding of psychedelic-induced neuroplasticity
10.1038/s41386-022-01389-z · 2022 · External reference
Activity-Dependent Remodeling of Drosophila Olfactory Sensory Neuron Brain Innervation during an Early-Life Critical Period
10.1523/jneurosci.2223-18.2019 · 2019 · External reference
Neuron-Specific FMRP Roles in Experience-Dependent Remodeling of Olfactory Brain Innervation During an Early-life Critical Period
2021 · External reference
Fragile X mental retardation protein coordinates neuron-to-glia communication for clearance of developmentally transient brain neurons
10.1073/pnas.2216887120 · 2023 · External reference
Neuronal fragile X mental retardation protein activates glial insulin receptor mediated PDF-Tri neuron developmental clearance
10.1038/s41467-021-21429-4 · 2021 · External reference
DoOR 2.0—Comprehensive Mapping of Drosophila melanogaster Odorant Responses.
10.1038/srep21841 · 2016 · External reference
Genetic and functional subdivision of the Drosophila antennal lobe
10.1016/j.cub.2005.07.066 · 2005 · External reference
The olfactory sensory map in Drosophila
10.1007/978-0-387-78261-4_7 · 2008 · External reference
Drosophila Psidin Regulates Olfactory Neuron Number and Axon Targeting through Two Distinct Molecular Mechanisms
10.1523/jneurosci.3116-12.2012 · 2012 · External reference
Functional integration of a serotonergic neuron in the drosophila antennal lobe
2016 · External reference
Dying Neurons Utilize Innate Immune Signaling to Prime Glia for Phagocytosis during Development
10.1016/j.devcel.2018.12.019 · 2019 · External reference
Developmental experience-dependent plasticity in the first synapse of the Drosophila olfactory circuit
10.1152/jn.00616.2016 · 2016 · External reference
10.1093/molbev/msz018
10.1093/molbev/msz018 · External reference
Serotonin synthesis by two distinct enzymes in Drosophila melanogaster
2005 · External reference
Neural specificity of the RNA-binding protein elav is achieved by post-transcriptional repression in non-neural tissues
10.1242/dev.141978 · 2016 · External reference
Autism-like behaviors regulated by the serotonin receptor 5-HT2B in the dorsal fan-shaped body neurons of Drosophila melanogaster
2022 · External reference
Microglia Function on Precursor Cells in the Adult Hippocampus and Their Responsiveness to Serotonin Signaling.
10.3389/fcell.2021.665739 · 2021 · External reference
Neuron-glia interaction through Serotonin-BDNF-NGFR axis enables regenerative neurogenesis in Alzheimer’s model of adult zebrafish brain
2020 · External reference
Errant gardeners: glial-cell-dependent synaptic pruning and neurodevelopmental disorders.
10.1038/nrn.2017.110 · 2017 · External reference
Engulfed by Glia: Glial Pruning in Development, Function, and Injury across Species
10.1523/jneurosci.1660-20.2020 · 2021 · External reference
Serotonin distinctly controls behavioral states in restrained and freely moving Drosophila.
10.1016/j.isci.2022.105886 · 2023 · External reference
Hallucinogens and Serotonin 5-HT2A Receptor-Mediated Signaling Pathways.
10.1007/7854_2017_478 · 2018 · External reference
Critical Period Plasticity as a Framework for Psychedelic-Assisted Psychotherapy.
10.3389/fnins.2021.710004 · 2021 · External reference
Light, heat, action: neural control of fruit fly behaviour
2015 · External reference
Refining the Role of 5-HT in Postnatal Development of Brain Circuits.
10.3389/fncel.2017.00139 · 2017 · External reference
Involvement of serotonin in developmental plasticity of kitten visual cortex
10.1111/j.1460-9568.1995.tb01104.x · 1995 · External reference
Serotonin modulates excitatory synapse maturation in the developing prefrontal cortex
2024 · External reference
Sensory neuron lineage mapping and manipulation in the Drosophila olfactory system
2019 · External reference
The community effect, dorsalization and mesoderm induction
10.1016/0959-437x(93)90104-w · 1993 · External reference
Theoretical basis of the community effect in development
10.1186/1752-0509-5-54 · 2011 · External reference
5-HT2A receptor dysregulation in a schizophrenia relevant mouse model of NMDA receptor hypofunction
10.1038/s41398-022-01930-0 · 2022 · External reference
Serotonin regulation of behavior via large-scale neuromodulation of serotonin receptor networks
10.1038/s41593-022-01213-3 · 2022 · External reference
Serotonin modulates the response of embryonic thalamocortical axons to netrin-1
10.1038/nn1896 · 2007 · External reference
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB
10.1038/s41593-023-01316-5 · 2023 · External reference
Neurotrophin regulation of neural circuit development and function
10.1038/nrn3379 · 2013 · External reference
Critical Periods in the Visual System: Changing Views for a Model of Experience-Dependent Plasticity
10.1016/j.neuron.2007.10.003 · 2007 · External reference
Glia as Architects of Central Nervous System Formation and Function
10.1126/science.aat0473 · 2018 · External reference
Astrocytes and microglia in the coordination of CNS development and homeostasis
2023 · External reference
Activation of Serotonin 5-HT7 Receptors Modulates Hippocampal Synaptic Plasticity by Stimulation of Adenylate Cyclases and Rescues Learning and Behavior in a Mouse Model of Fragile X Syndrome.
10.3389/fnmol.2018.00353 · 2018 · External reference
MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study
10.1038/s41591-021-01336-3 · 2021 · External reference
Review of potential psychedelic treatments for PTSD
2022 · External reference
Microglia in neurological diseases: A road map to brain-disease dependent-inflammatory response
10.3389/fncel.2018.00488 · 2018 · External reference
Synaptic plasticity and mental health: methods, challenges and opportunities
10.1038/s41386-022-01370-w · 2022 · External reference
Serotonin and brain function: A tale of two receptors
10.1177/0269881117725915 · 2017 · External reference
Psychedelic-inspired approaches for treating neurodegenerative disorders
10.1111/jnc.15544 · 2022 · External reference
Relevance of 5-HT2A Receptor Modulation of Pyramidal Cell Excitability for Dementia-Related Psychosis: Implications for Pharmacotherapy.
10.1007/s40263-021-00836-7 · 2021 · External reference
Psychedelics and Neural Plasticity: Therapeutic Implications
10.1523/jneurosci.1121-22.2022 · 2022 · External reference
Microglia and cognitive impairment in schizophrenia: translating scientific progress into novel therapeutic interventions
10.1038/s41537-023-00370-z · 2023 · External reference
Serotonin depletion during the postnatal developmental period causes behavioral and cognitive alterations and decreases BDNF level in the brain of rats
10.1002/jdn.10087 · 2021 · External reference
Serotonergic Neuroplasticity in Alcohol Addiction.
10.3233/bpl-150022 · 2016 · External reference
Senseless and Daughterless confer neuronal identity to epithelial cells in the Drosophila wing margin
10.1242/dev.02338 · 2006 · External reference
The homeobox gene repo is required for the differentiation and maintenance of glia function in the embryonic nervous system of Drosophila melanogaster
10.1242/dev.121.2.317 · 1995 · External reference
Local synaptic inputs support opposing, network-specific odor representations in a widely projecting modulatory neuron.
2019 · External reference
Targeted manipulation of serotonergic neurotransmission affects the escalation of aggression in adult male Drosophila melanogaster.
2010 · External reference
Activity-dependent FMRP requirements in development of the neural circuitry of learning and memory
10.1242/dev.117127 · 2015 · External reference
Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis
10.1016/s0896-6273(00)80701-1 · 1999 · External reference
Local 5-HT signaling bi-directionally regulates the coincidence time window for associative learning
10.1016/j.neuron.2022.12.034 · 2023 · External reference
An SH3PX1-Dependent Endocytosis-Autophagy Network Restrains Intestinal Stem Cell Proliferation by Counteracting EGFR-ERK Signaling
10.1016/j.devcel.2019.03.029 · 2019 · External reference
Experience-Dependent Remodeling of Juvenile Brain Olfactory Sensory Neuron Synaptic Connectivity in an Early-Life Critical Period.
2024 · External reference
