Research graph
References from Structural characterization of the YbbAP-TesA ABC transporter identifies it as a lipid hydrolase complex that extracts hydrophobic compounds from the bacterial inner membrane. Local targets link to admitted publications; unresolved targets remain external evidence.
Structural and functional diversity calls for a new classification of ABC transporters
10.1002/1873-3468.13935 · 2020 · External reference
Antibiotic resistance mediated by the MacB ABC transporter family: a structural and functional perspective
10.3389/fmicb.2018.00950 · 2018 · External reference
Structure and mechanotransmission mechanism of the MacB ABC transporter superfamily
10.1073/pnas.1712153114 · 2017 · External reference
Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump
10.1038/nmicrobiol.2017.70 · 2017 · External reference
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II
10.1128/jb.00853-08 · 2008 · External reference
Insights into bacterial lipoprotein trafficking from a structure of LolA bound to the LolC periplasmic domain
10.1073/pnas.1806822115 · 2018 · External reference
Structural basis of lipoprotein recognition by the bacterial Lol trafficking chaperone LolA
10.1073/pnas.2208662119 · 2022 · External reference
Cryo-EM structures of LolCDE reveal the molecular mechanism of bacterial lipoprotein sorting in Escherichia coli
2022 · External reference
Genetic analysis reveals a robust and hierarchical recruitment of the LolA chaperone to the LolCDE lipoprotein transporter
10.1128/mbio.03039-23 · 2024 · External reference
Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins
10.1038/s41467-021-24965-1 · 2021 · External reference
Structural basis for bacterial lipoprotein relocation by the transporter LolCDE
10.1038/s41594-021-00573-x · 2021 · External reference
Structural insights into the mechanotransducing mechanism of FtsEX in cell division
2024 · External reference
Structural insights into the FtsEX-EnvC complex regulation on septal peptidoglycan hydrolysis in Vibrio cholerae
2024 · External reference
Insights into bacterial cell division from a structure of EnvC bound to the FtsX periplasmic domain
10.1073/pnas.2017134117 · 2020 · External reference
Activator-induced conformational changes regulate division-associated peptidoglycan amidases
10.1073/pnas.2302580120 · 2023 · External reference
Regulation of the cell division hydrolase RipC by the FtsEX system in Mycobacterium tuberculosis
10.1038/s41467-023-43770-6 · 2023 · External reference
Mechanistic insights into the regulation of cell wall hydrolysis by FtsEX and EnvC at the bacterial division site
2023 · External reference
10.7554/elife.94336
10.7554/elife.94336 · External reference
A conformational switch controls cell wall-remodelling enzymes required for bacterial cell division
10.1111/j.1365-2958.2012.08138.x · 2012 · External reference
An ATP-binding cassette transporter-like complex governs cell-wall hydrolysis at the bacterial cytokinetic ring
2011 · External reference
Mycobacterium tuberculosis FtsX extracellular domain activates the peptidoglycan hydrolase, RipC
10.1073/pnas.1321812111 · 2014 · External reference
Evolutionary relationships of ATP-Binding Cassette (ABC) uptake porters
10.1186/1471-2180-13-98 · 2013 · External reference
The export of coat protein from enteroaggregative Escherichia coli by a specific ATP-binding cassette transporter system
10.1074/jbc.m306413200 · 2003 · External reference
Glycine acylation and trafficking of a new class of bacterial lipoprotein by a composite secretion system
10.7554/elife.63762 · 2021 · External reference
Molecular basis of pyoverdine siderophore recycling in Pseudomonas aeruginosa
10.1073/pnas.0908760106 · 2009 · External reference
Deciphering the molecular basis of lipoprotein recognition and transport by LolCDE
10.1038/s41392-024-02067-w · 2024 · External reference
A new ABC transporter mediating the detachment of lipid-modified proteins from membranes
10.1038/35008635 · 2000 · External reference
Disruption of lolCDE, encoding an ATP-binding cassette transporter, is lethal for Escherichia coli and prevents release of lipoproteins from the inner membrane
10.1128/jb.184.5.1417-1422.2002 · 2002 · External reference
Genetic analyses of the in vivo function of LolA, a periplasmic chaperone involved in the outer membrane localization of Escherichia coli lipoproteins
10.1016/s0014-5793(98)01334-9 · 1998 · External reference
Perception and protection: the role of Bce-modules in antimicrobial peptide resistance
10.1016/j.bbamem.2024.184309 · 2024 · External reference
Conformational snapshots of the bacitracin sensing and resistance transporter BceAB
10.1073/pnas.2123268119 · 2022 · External reference
Architecture of a complete Bce-type antimicrobial peptide resistance module
10.1038/s41467-023-39678-w · 2023 · External reference
BceAB-type antibiotic resistance transporters appear to act by target protection of cell wall synthesis
10.1128/aac.02241-19 · 2020 · External reference
Improved prediction of protein-protein interactions using AlphaFold2
10.1038/s41467-022-28865-w · 2022 · External reference
Highly accurate protein structure prediction with AlphaFold
10.1038/s41586-021-03819-2 · 2021 · External reference
ColabFold: making protein folding accessible to all
10.1038/s41592-022-01488-1 · 2022 · External reference
The Escherichia coli pldC gene encoding lysophospholipase j is identical to the apeA and tesA genes encoding protease I and thioesterase I, respectively
10.1093/oxfordjournals.jbchem.a022470 · 1999 · External reference
Structural and functional characterisation of TesA - a novel lysophospholipase A from Pseudomonas aeruginosa
10.1371/journal.pone.0069125 · 2013 · External reference
MolProbity: more and better reference data for improved all-atom structure validation
10.1002/pro.3330 · 2018 · External reference
GDSL family of serine esterases/lipases
10.1016/j.plipres.2004.09.002 · 2004 · External reference
KEGG: Kyoto encyclopedia of genes and genomes
10.1093/nar/28.1.27 · 2000 · External reference
CCMpred--fast and precise prediction of protein residue-residue contacts from correlated mutations
10.1093/bioinformatics/btu500 · 2014 · External reference
Purification and properties of fatty acyl thioesterase I from Escherichia coli
10.1016/s0021-9258(19)45222-8 · 1972 · External reference
The thioesterase I of Escherichia coli has arylesterase activity and shows stereospecificity for protease substrates
10.1006/bbrc.1997.5797 · 1997 · External reference
Lysophospholipase L1 from Escherichia coli K-12 Overproducer1
1991 · External reference
Molecular cloning, sequencing, and mapping of the gene encoding protease I and characterization of proteinase and proteinase-defective Escherichia coli mutants
10.1128/jb.175.4.1032-1037.1993 · 1993 · External reference
Tissue sulfhydryl groups
10.1016/0003-9861(59)90090-6 · 1959 · External reference
Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrate
10.1128/aac.1.4.283 · 1972 · External reference
Crystal structure of Escherichia coli thioesterase I/protease I/lysophospholipase L1: consensus sequence blocks constitute the catalytic center of SGNH-hydrolases through a conserved hydrogen bond network
10.1016/s0022-2836(03)00637-5 · 2003 · External reference
Biogenesis, transport and remodeling of lysophospholipids in Gram-negative bacteria
10.1016/j.bbalip.2016.11.015 · 2017 · External reference
Kinetics and phospholipid specificity of apolipoprotein N-acyltransferase
10.1074/jbc.m111.243519 · 2011 · External reference
Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis
10.1038/ncomms15952 · 2017 · External reference
Structure snapshots reveal the mechanism of a bacterial membrane lipoprotein N-acyltransferase
10.1126/sciadv.adf5799 · 2023 · External reference
Antibacterial actions of secreted phospholipases A2. Review
10.1016/j.bbalip.2007.12.001 · 2008 · External reference
Molecular determinants of bacterial sensitivity and resistance to mammalian Group IIA phospholipase A2
10.1016/j.bbamem.2015.05.018 · 2015 · External reference
Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors
10.1038/nature12074 · 2013 · External reference
An image processing pipeline for electron cryo-tomography in RELION-5
10.1002/2211-5463.13873 · 2024 · External reference
Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
10.1107/s2059798319011471 · 2019 · External reference
Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection
10.1038/msb4100050 · 2006 · External reference
GROMACS: high performance molecular simulations through multi-level parallelism from laptops to supercomputers
10.1016/j.softx.2015.06.001 · 2015 · External reference
Membrane protein orientation and refinement using a knowledge-based statistical potential
10.1186/1471-2105-14-276 · 2013 · External reference
Computational lipidomics with insane: a versatile tool for generating custom membranes for molecular simulations
10.1021/acs.jctc.5b00209 · 2015 · External reference
CHARMM36m: an improved force field for folded and intrinsically disordered proteins
10.1038/nmeth.4067 · 2017 · External reference
PLUMED 2: new feathers for an old bird
10.1016/j.cpc.2013.09.018 · 2014 · External reference
MDAnalysis: a toolkit for the analysis of molecular dynamics simulations
10.1002/jcc.21787 · 2011 · External reference
Unresolved reference
2015 · External reference