Research graph
References from The planarian dorsal–ventral boundary regulates anterior–posterior axis growth and patterning. Local targets link to admitted publications; unresolved targets remain external evidence.
Regeneration in the metazoans: why does it happen?
10.1002/(sici)1521-1878(200006)22:6<578::aid-bies11>3.0.co;2-# · 2000 · External reference
Beyond casual resemblance: rigorous frameworks for comparing regeneration across species
10.1146/annurev-cellbio-120319-114716 · 2021 · External reference
Fundamentals of planarian regeneration
10.1146/annurev.cellbio.20.010403.095114 · 2004 · External reference
Positional information and the spatial pattern of cellular differentiation
10.1016/s0022-5193(69)80016-0 · 1969 · External reference
A common plan for dorsoventral patterning in Bilateria
10.1038/380037a0 · 1996 · External reference
Wnt signaling and the polarity of the primary body axis
10.1016/j.cell.2009.11.035 · 2009 · External reference
On growth and form: a Cartesian coordinate system of Wnt and BMP signaling specifies bilaterian body axes
10.1242/dev.039651 · 2010 · External reference
Morphogen rules: design principles of gradient-mediated embryo patterning
10.1242/dev.129452 · 2015 · External reference
Muscle cells provide instructions for planarian regeneration
10.1016/j.celrep.2013.07.022 · 2013 · External reference
The cellular and molecular basis for planarian regeneration
10.1016/j.cell.2018.09.021 · 2018 · External reference
Beta-catenin defines head versus tail identity during planarian regeneration and homeostasis
10.1126/science.1150029 · 2008 · External reference
Silencing of Smed-betacatenin1 generates radial-like hypercephalized planarians
10.1242/dev.020289 · 2008 · External reference
Smed-betacatenin-1 is required for anteroposterior blastema polarity in planarian regeneration
10.1126/science.1149943 · 2008 · External reference
Smed-Evi/Wntless is required for beta-catenin-dependent and -independent processes during planarian regeneration
10.1242/dev.033761 · 2009 · External reference
A wound-induced Wnt expression program controls planarian regeneration polarity
10.1073/pnas.0906823106 · 2009 · External reference
Expression of secreted Wnt pathway components reveals unexpected complexity of the planarian amputation response
10.1016/j.ydbio.2010.08.007 · 2010 · External reference
Polarized notum activation at wounds inhibits Wnt function to promote planarian head regeneration
10.1126/science.1202143 · 2011 · External reference
Β-catenin-dependent control of positional information along the AP body axis in planarians involves a teashirt family member
10.1016/j.celrep.2014.12.018 · 2015 · External reference
Antagonistic self-organizing patterning systems control maintenance and regeneration of the anteroposterior axis in planarians
10.1016/j.devcel.2016.12.024 · 2017 · External reference
A small set of conserved genes, including sp5 and Hox, are activated by Wnt signaling in the posterior of planarians and acoels
10.1371/journal.pgen.1008401 · 2019 · External reference
Wnt, Ptk7, and FGFRL expression gradients control trunk positional identity in planarian regeneration
10.7554/elife.12850 · 2016 · External reference
Two FGFRL-Wnt circuits organize the planarian anteroposterior axis
10.7554/elife.12845 · 2016 · External reference
Src acts with WNT/FGFRL signaling to pattern the planarian anteroposterior axis
10.1242/dev.200125 · 2022 · External reference
Molecular cloning of Bone Morphogenetic Protein (BMP) gene from the planarian Dugesia japonica
10.2108/zsj.15.871 · 1998 · External reference
The BMP pathway is essential for re-specification and maintenance of the dorsoventral axis in regenerating and intact planarians
10.1016/j.ydbio.2007.08.019 · 2007 · External reference
BMP signaling regulates the dorsal planarian midline and is needed for asymmetric regeneration
10.1242/dev.007138 · 2007 · External reference
Bone morphogenetic protein is required for dorso-ventral patterning in the planarian Dugesia japonica
10.1111/j.1440-169x.2007.00931.x · 2007 · External reference
The planarian wound epidermis gene equinox is required for blastema formation in regeneration
10.1038/s41467-022-30412-6 · 2022 · External reference
Different strategies for midline formation in bilaterians
10.1038/nrn1410 · 2004 · External reference
Beta-catenin and axis formation in planarians
10.1002/bies.080193 · 2009 · External reference
A forkhead transcription factor is wound-induced at the planarian midline and required for anterior pole regeneration
10.1371/journal.pgen.1003999 · 2014 · External reference
Stem cell-dependent formation of a functional anterior regeneration pole in planarians requires Zic and Forkhead transcription factors
10.1016/j.ydbio.2014.03.016 · 2014 · External reference
zic-1 expression in planarian neoblasts after injury controls anterior pole regeneration
10.1371/journal.pgen.1004452 · 2014 · External reference
Landmarks in existing tissue at wounds are utilized to generate pattern in regenerating tissue
10.1016/j.cub.2017.01.024 · 2017 · External reference
Interaction between dorsal and ventral cells in the imaginal disc directs wing development in Drosophila
10.1016/0092-8674(93)90494-b · 1993 · External reference
Serrate signals through Notch to establish a Wingless-dependent organizer at the dorsal/ventral compartment boundary of the Drosophila wing
10.1242/dev.121.12.4215 · 1995 · External reference
The dynamics of wound closure and its role in the programming of planarian regeneration I—blastema emergence
10.1111/j.1440-169x.1979.00195.x · 1979 · External reference
The role of dorsoventral interaction in the onset of planarian regeneration
10.1242/dev.126.5.1031 · 1999 · External reference
BMP suppresses WNT to integrate patterning of orthogonal body axes in adult planarians
10.1371/journal.pgen.1010608 · 2023 · External reference
The body margin of the planarian Dugesia japonica: characterization by the expression of an intermediate filament gene
10.1007/s00427-002-0253-0 · 2002 · External reference
A Bmp/Admp regulatory circuit controls maintenance and regeneration of dorsal-ventral polarity in planarians
10.1016/j.cub.2011.01.017 · 2011 · External reference
Noggin and noggin-like genes control dorsoventral axis regeneration in planarians
10.1016/j.cub.2011.01.016 · 2011 · External reference
A LIM-homeobox gene is required for differentiation of Wnt-expressing cells at the posterior end of the planarian body
10.1242/dev.060194 · 2011 · External reference
Orthogonal muscle fibres have different instructive roles in planarian regeneration
10.1038/nature24660 · 2017 · External reference
foxF-1 controls specification of non-body wall muscle and phagocytic cells in planarians
10.1016/j.cub.2018.10.030 · 2018 · External reference
Planarian dorsoventral Netrins control a muscle midline signaling center and regulate blastema formation
2022 · External reference
Planarian homologs of netrin and netrin receptor are required for proper regeneration of the central nervous system and the maintenance of nervous system architecture
10.1242/dev.01941 · 2005 · External reference
Evolution of the EGFR pathway in Metazoa and its diversification in the planarian Schmidtea mediterranea
10.1038/srep28071 · 2016 · External reference
Tissue absence initiates regeneration through follistatin-mediated inhibition of activin signaling
10.7554/elife.00247 · 2013 · External reference
Follistatin antagonizes activin signaling and acts with notum to direct planarian head regeneration
10.1073/pnas.1214053110 · 2013 · External reference
Cell type transcriptome atlas for the planarian Schmidtea mediterranea
10.1126/science.aaq1736 · 2018 · External reference
SED1/MFG-E8: a bi-motif protein that orchestrates diverse cellular interactions
10.1002/jcb.22076 · 2009 · External reference
Eph/ephrin signalling during development
10.1242/dev.074997 · 2012 · External reference
Let’s stick together: the role of the Fras1 and Frem proteins in epidermal adhesion
10.1080/15216540701510581 · 2007 · External reference
Netrins: versatile extracellular cues with diverse functions
10.1242/dev.044529 · 2011 · External reference
The canonical Notch signaling pathway: unfolding the activation mechanism
10.1016/j.cell.2009.03.045 · 2009 · External reference
Regulatory potential of COUP-TFs in development: stem/progenitor cells
10.1016/j.semcdb.2013.08.005 · 2013 · External reference
Dorsal and ventral positional cues required for the onset of planarian regeneration may reside in differentiated cells
10.1006/dbio.2001.0226 · 2001 · External reference
Mitosis in the intact and regenerating planarian Dugesia mediterranea n.sp. II. Mitotic studies during regeneration, and a possible mechanism of blastema formation
10.1002/jez.1401950107 · 1976 · External reference
Planarian regeneration involves distinct stem cell responses to wounds and tissue absence
10.1016/j.ydbio.2010.06.017 · 2010 · External reference
Generic wound signals initiate regeneration in missing-tissue contexts
10.1038/s41467-017-02338-x · 2017 · External reference
The origin of pattern and polarity in the Drosophila embryo
10.1016/0092-8674(92)90466-p · 1992 · External reference
Tissue transplantation in planarians: a useful tool for molecular analysis of pattern formation
10.1016/j.semcdb.2018.05.022 · 2019 · External reference
A PAK family kinase and the Hippo/Yorkie pathway modulate WNT signaling to functionally integrate body axes during regeneration
10.1073/pnas.2321919121 · 2024 · External reference
Regionally specific induction by the Spemann-Mangold organizer
10.1038/nrg1347 · 2004 · External reference
Molecular genetics of axis formation in zebrafish
10.1146/annurev.genet.37.110801.143752 · 2005 · External reference
Spemann’s organizer and self-regulation in amphibian embryos
10.1038/nrm1855 · 2006 · External reference
A morphogen gradient of Wnt/beta-catenin signalling regulates anteroposterior neural patterning in Xenopus
10.1242/dev.128.21.4189 · 2001 · External reference
Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal
10.1016/j.cell.2007.09.027 · 2007 · External reference
Bmp activity gradient regulates convergent extension during zebrafish gastrulation
10.1006/dbio.2001.0523 · 2002 · External reference
The wing imaginal disc
10.1093/genetics/iyac020 · 2022 · External reference
The proximo-distal sequence of origin of the parts of the chick wing and the role of the ectoderm
10.1002/jez.1401080304 · 1948 · External reference
A quantitative analysis of the effect of excision of the AER from the chick limb-bud
1974 · External reference
Fgf8 signalling from the AER is essential for normal limb development
10.1038/82609 · 2000 · External reference
Pattern regulation and the origin of extra parts following axial misalignments in the urodele limb bud
1980 · External reference
Supernumerary limgs in amphibians: experimental production in Notophthalmus viridescens and a new interpretation of their formation
10.1016/0012-1606(76)90079-8 · 1976 · External reference
Duplicated axolotl regenerates
1979 · External reference
The structure of supernumerary leg regenerates in the cricket
1984 · External reference
Positional memory in vertebrate regeneration: a century’s insights from the salamander limb
10.1101/cshperspect.a040899 · 2022 · External reference
Pattern regulation in epimorphic fields
10.1126/science.948762 · 1976 · External reference
Distal regeneration and symmetry
10.1126/science.212.4498.993 · 1981 · External reference
A boundary model for pattern formation in vertebrate limbs
1983 · External reference
Negative selection by spiral inertial microfluidics improves viral recovery and sequencing from blood
10.1021/acs.analchem.7b05200 · 2018 · External reference
A generic and cell-type-specific wound response precedes regeneration in planarians
10.1016/j.devcel.2015.11.004 · 2015 · External reference
Identification of genes needed for regeneration, stem cell function, and tissue homeostasis by systematic gene perturbation in planaria
10.1016/j.devcel.2005.02.014 · 2005 · External reference
