Research graph
References from Sleep deprivation and sleep intensity exert distinct effects on cerebral vasomotion and brain pulsations driven by the respiratory and cardiac cycles. Local targets link to admitted publications; unresolved targets remain external evidence.
The two-process model of sleep regulation: a reappraisal
10.1111/jsr.12371 · 2016 · External reference
A two process model of sleep regulation
1982 · External reference
Sleep homeostasis and models of sleep regulation
1999 · External reference
Dual function of thalamic low-vigilance state oscillations: rhythm-regulation and plasticity
10.1038/nrn.2017.151 · 2018 · External reference
Modulating overnight memory consolidation by acoustic stimulation during slow-wave sleep: a systematic review and meta-analysis
10.1093/sleep/zsaa296 · 2021 · External reference
Sleep function: toward elucidating an enigma
10.1016/j.smrv.2015.08.005 · 2016 · External reference
Fluid transport in the brain
10.1152/physrev.00031.2020 · 2022 · External reference
Sleep drives metabolite clearance from the adult brain
10.1126/science.1241224 · 2013 · External reference
Increased glymphatic influx is correlated with high EEG delta power and low heart rate in mice under anesthesia
10.1126/sciadv.aav5447 · 2019 · External reference
Changes in the composition of brain interstitial ions control the sleep-wake cycle
10.1126/science.aad4821 · 2016 · External reference
A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β
10.1126/scitranslmed.3003748 · 2012 · External reference
Glymphatic clearance controls state-dependent changes in brain lactate concentration
10.1177/0271678x16661202 · 2017 · External reference
The glymphatic system: a novel component of fundamental neurobiology
10.1523/jneurosci.0619-21.2021 · 2021 · External reference
Vasomotion as a driving force for paravascular clearance in the awake mouse brain
10.1016/j.neuron.2019.10.033 · 2020 · External reference
Glymphatic influx and clearance are accelerated by neurovascular coupling
10.1038/s41593-023-01327-2 · 2023 · External reference
Changes in intrathoracic pressure, not arterial pulsations, exert the greatest effect on tracer influx in the spinal cord
10.1186/s12987-022-00310-6 · 2022 · External reference
Ultra-fast magnetic resonance encephalography of physiological brain activity—glymphatic pulsation mechanisms?
10.1177/0271678x15622047 · 2016 · External reference
Inspiration is the major regulator of human CSF flow
10.1523/jneurosci.3246-14.2015 · 2015 · External reference
Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension
10.1038/s41467-018-07318-3 · 2018 · External reference
Cerebral arterial pulsation drives paravascular CSF-interstitial fluid exchange in the murine brain
10.1523/jneurosci.1592-13.2013 · 2013 · External reference
Sleep cycle-dependent vascular dynamics in male mice and the predicted effects on perivascular cerebrospinal fluid flow and solute transport
10.1038/s41467-023-36643-5 · 2023 · External reference
Multisensory gamma stimulation promotes glymphatic clearance of amyloid
10.1038/s41586-024-07132-6 · 2024 · External reference
Norepinephrine-mediated slow vasomotion drives glymphatic clearance during sleep
10.1016/j.cell.2024.11.027 · 2025 · External reference
Non-invasive imaging of CSF-mediated brain clearance pathways via assessment of perivascular fluid movement with diffusion tensor MRI
10.7554/elife.34028 · 2018 · External reference
Apparent diffusion coefficient changes in human brain during sleep—does it inform on the existence of a glymphatic system?
10.1016/j.neuroimage.2018.10.043 · 2019 · External reference
Sleep-related and diurnal effects on brain diffusivity and cerebrospinal fluid flow
10.1016/j.neuroimage.2021.118420 · 2021 · External reference
Nocturnal increase in cerebrospinal fluid secretion as a circadian regulator of intracranial pressure
10.1186/s12987-023-00451-2 · 2023 · External reference
Coupled electrophysiological, hemodynamic, and cerebrospinal fluid oscillations in human sleep
10.1126/science.aax5440 · 2019 · External reference
Evidence for wakefulness-related changes to extracellular space in human brain white matter from diffusion-weighted MRI
10.1016/j.neuroimage.2020.116682 · 2020 · External reference
Sleep deprivation impairs molecular clearance from the human brain
10.1093/brain/awaa443 · 2021 · External reference
β-Amyloid accumulation in the human brain after one night of sleep deprivation
10.1073/pnas.1721694115 · 2018 · External reference
The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans
10.1126/science.aav2546 · 2019 · External reference
Effect of sleep on overnight cerebrospinal fluid amyloid β kinetics
10.1002/ana.25117 · 2018 · External reference
Intracranial pressure oscillations (B-waves) caused by oscillations in cerebrovascular volume
10.1007/bf01406205 · 1983 · External reference
Rhythmic oscillations with a wavelength of 0.5-2 min in transcranial Doppler recordings
10.1111/j.1600-0404.1994.tb02687.x · 1994 · External reference
The relation of intracranial pressure B-waves to different sleep stages in patients with suspected normal pressure hydrocephalus
10.1007/bf01410626 · 1995 · External reference
Single shot whole brain imaging using spherical stack of spirals trajectories
10.1016/j.neuroimage.2013.01.065 · 2013 · External reference
15 Years MR-encephalography
10.1007/s10334-020-00891-z · 2021 · External reference
Human NREM sleep promotes brain-wide vasomotor and respiratory Pulsations
10.1523/jneurosci.0934-21.2022 · 2022 · External reference
Effect of sleep deprivation and NREM sleep stage on physiological brain pulsations
10.3389/fnins.2023.1275184 · 2023 · External reference
Ultra-slow fMRI fluctuations in the fourth ventricle as a marker of drowsiness
10.1016/j.neuroimage.2022.119424 · 2022 · External reference
Autonomic arousals contribute to brain fluid pulsations during sleep
10.1016/j.neuroimage.2022.118888 · 2022 · External reference
Nonselective versus selective beta-adrenergic receptor blockade in congestive heart failure: differential effects on sympathetic activity
10.1161/hc4301.098282 · 2001 · External reference
Mechanical properties of gray and white matter brain tissue by indentation
10.1016/j.jmbbm.2015.02.024 · 2015 · External reference
In vivo measurement of T2 distributions and water contents in normal human brain
10.1002/mrm.1910370107 · 1997 · External reference
Carvedilol. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy
1993 · External reference
New positron emission tomography tracer [(11)C]carvedilol reveals P-glycoprotein modulation kinetics
10.1038/sj.bjp.0706283 · 2005 · External reference
Sustained attention performance during sleep deprivation: evidence of state instability
2001 · External reference
Maximizing sensitivity of the psychomotor vigilance test (PVT) to sleep loss
10.1093/sleep/34.5.581 · 2011 · External reference
10.1364/ecbo.2011.808806
10.1364/ecbo.2011.808806 · External reference
Neuronal dynamics direct cerebrospinal fluid perfusion and brain clearance
10.1038/s41586-024-07108-6 · 2024 · External reference
The glymphatic system: current understanding and modeling
10.1016/j.isci.2022.104987 · 2022 · External reference
Low-frequency (< 1 Hz) oscillations in the human sleep electroencephalogram
10.1016/s0306-4522(97)00186-3 · 1997 · External reference
Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs
10.1016/j.jconrel.2019.05.005 · 2019 · External reference
Blood-brain barrier permeable β-blockers linked to lower risk of Alzheimer’s disease in hypertension
10.1093/brain/awac076 · 2023 · External reference
PET Studies on P-glycoprotein function in the blood-brain barrier: how it affects uptake and binding of drugs within the CNS
10.2174/1381612043384736 · 2004 · External reference
Circadian rhythms, sleep, and the menstrual cycle
10.1016/j.sleep.2006.09.011 · 2007 · External reference
Biological sex does not predict glymphatic influx in healthy young, middle aged or old mice
10.1038/s41598-020-72621-3 · 2020 · External reference
The ten-twenty electrode system of the International Federation. The International Federation of Clinical Neurophysiology
1999 · External reference
Fast undersampled functional magnetic resonance imaging using nonlinear regularized parallel image reconstruction
10.1371/journal.pone.0028822 · 2011 · External reference
A method for removing imaging artifact from continuous EEG recorded during functional MRI
10.1006/nimg.2000.0599 · 2000 · External reference
Removal of FMRI environment artifacts from EEG data using optimal basis sets
10.1016/j.neuroimage.2005.06.067 · 2005 · External reference
Interobserver agreement among sleep scorers from different centers in a large dataset
10.1093/sleep/23.7.1e · 2000 · External reference
EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis
10.1016/j.jneumeth.2003.10.009 · 2004 · External reference
B-waves revisited
10.1016/j.inat.2016.03.004 · 2016 · External reference
TAPAS: an open-source software package for translational neuromodeling and computational psychiatry
10.3389/fpsyt.2021.680811 · 2021 · External reference
Sleep deprivation and vigilant attention
10.1196/annals.1417.002 · 2008 · External reference
Separating neural oscillations from aperiodic 1/f activity: challenges and recommendations
10.1007/s12021-022-09581-8 · 2022 · External reference