Research graph
References from The efficacy of longevity interventions in Caenorhabditis elegans is determined by the early life activity of RNA splicing factors. Local targets link to admitted publications; unresolved targets remain external evidence.
Metabolic communication and healthy aging: where should we focus our energy?
10.1016/j.devcel.2020.06.011 · 2020 · External reference
Predicting longevity responses to dietary restriction: a stepping stone toward precision geroscience
2020 · External reference
Alternative splicing in aging and longevity
10.1007/s00439-019-02094-6 · 2020 · External reference
Changes in the expression of splicing factor transcripts and variations in alternative splicing are associated with lifespan in mice and humans
10.1111/acel.12499 · 2016 · External reference
Copy number variations in alternative splicing gene networks impact lifespan
10.1371/journal.pone.0053846 · 2013 · External reference
Corrigendum: Splicing factor 1 modulates dietary restriction and TORC1 pathway longevity in C. elegans
10.1038/nature23313 · 2017 · External reference
Differential alternative splicing coupled to nonsense-mediated decay of mRNA ensures dietary restriction-induced longevity
10.1038/s41467-017-00370-5 · 2017 · External reference
RNA surveillance via nonsense-mediated mRNA decay is crucial for longevity in daf-2/insulin/IGF-1 mutant C. elegans
10.1038/ncomms14749 · 2017 · External reference
Position-dependent and neuron-specific splicing regulation by the CELF family RNA-binding protein UNC-75 in Caenorhabditis elegans
10.1093/nar/gkt097 · 2013 · External reference
WormCat: an online tool for annotation and visualization of Caenorhabditis elegans genome-scale data
10.1534/genetics.119.302919 · 2020 · External reference
Purification of splicing factor SF1, a heat-stable protein that functions in the assembly of a presplicing complex
1992 · External reference
Caloric restriction engages hepatic RNA processing mechanisms in rhesus monkeys
2018 · External reference
Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP)
10.1038/nmeth.3810 · 2016 · External reference
Mutations in the Caenorhabditis elegans U2AF large subunit UAF-1 alter the choice of a 3’ splice site in vivo
2009 · External reference
In vivo effects on intron retention and exon skipping by the U2AF large subunit and SF1/BBP in the nematode Caenorhabditis elegans
10.1261/rna.027458.111 · 2011 · External reference
Rates of behavior and aging specified by mitochondrial function during development
10.1126/science.1077780 · 2002 · External reference
Genetics: influence of TOR kinase on lifespan in C. elegans
10.1038/426620a · 2003 · External reference
Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects
10.1038/ncomms14256 · 2017 · External reference
Effects of sex, strain, and energy intake on hallmarks of aging in mice
10.1016/j.cmet.2016.05.027 · 2016 · External reference
Caloric restriction improves health and survival of rhesus monkeys
10.1038/ncomms14063 · 2017 · External reference
Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-I and insulin levels, and increases hepatocyte MIF levels and stress resistance
10.1111/j.1474-9726.2005.00152.x · 2005 · External reference
DAF-16 and TCER-1 facilitate adaptation to germline loss by restoring lipid homeostasis and repressing reproductive physiology in C. elegans
2016 · External reference
