Research graph
References from RNG2 tethers the conoid to the apical polar ring in Toxoplasma gondii to enable parasite motility and invasion. Local targets link to admitted publications; unresolved targets remain external evidence.
Diversity, nomenclature, and taxonomy of protists
10.1080/10635150701494127 · 2007 · External reference
Evolution, composition, assembly, and function of the conoid in Apicomplexa
10.1016/j.pt.2020.05.001 · 2020 · External reference
Cytoskeletal components of an invasion machine--the apical complex of Toxoplasma gondii
2006 · External reference
Gliding motility powers invasion and egress in Apicomplexa
10.1038/nrmicro.2017.86 · 2017 · External reference
Dynamics and 3D organization of secretory organelles of Toxoplasma gondii
10.1016/j.jsb.2011.11.028 · 2012 · External reference
The riveting cellular structures of Apicomplexan parasites
10.1016/j.pt.2020.09.001 · 2020 · External reference
Essential function of the alveolin network in the subpellicular microtubules and conoid assembly in Toxoplasma gondii
10.7554/elife.56635 · 2020 · External reference
Cytoskeleton of apicomplexan parasites
10.1128/mmbr.66.1.21-38.2002 · 2002 · External reference
Cytoskeleton of Toxoplasma gondii
10.1111/j.1550-7408.1987.tb03162.x · 1987 · External reference
A novel polymer of tubulin forms the conoid of Toxoplasma gondii
10.1083/jcb.200112086 · 2002 · External reference
Conoid extrusion regulates glideosome assembly to control motility and invasion in Apicomplexa
10.1038/s41564-022-01212-x · 2022 · External reference
Sustained rhoptry docking and discharge requires Toxoplasma gondii intraconoidal microtubule-associated proteins
10.1038/s41467-023-44631-y · 2024 · External reference
In situ ultrastructures of two evolutionarily distant apicomplexan rhoptry secretion systems
10.1038/s41467-021-25309-9 · 2021 · External reference
Cryo-electron tomography with mixed-scale dense neural networks reveals key steps in deployment of Toxoplasma invasion machinery
2022 · External reference
Induction and regulation of conoid extrusion in Toxoplasma gondii
10.1111/j.1462-5822.2009.01304.x · 2009 · External reference
Ca2+-dependence of conoid extrusion in Toxoplasma gondii tachyzoites
10.1111/j.1550-7408.1996.tb04491.x · 1996 · External reference
Origin and arrangement of actin filaments for gliding motility in apicomplexan parasites revealed by cryo-electron tomography
10.1038/s41467-023-40520-6 · 2023 · External reference
Ancient MAPK ERK7 is regulated by an unusual inhibitory scaffold required for Toxoplasma apical complex biogenesis
10.1073/pnas.1921245117 · 2020 · External reference
Stability and function of a putative microtubule-organizing center in the human parasite Toxoplasma gondii
10.1091/mbc.e17-01-0045 · 2017 · External reference
Revisiting the role of Toxoplasma gondii ERK7 in the maintenance and stability of the apical complex
10.1128/mbio.02057-21 · 2021 · External reference
RNG1 is a late marker of the apical polar ring in Toxoplasma gondii
10.1002/cm.20469 · 2010 · External reference
Architecture of the Toxoplasma gondii apical polar ring and its role in gliding motility and invasion
2024 · External reference
The apical complex provides a regulated gateway for secretion of invasion factors in Toxoplasma
10.1371/journal.ppat.1004074 · 2014 · External reference
A comprehensive ultrastructural analysis of the Toxoplasma gondii cytoskeleton
10.1007/s00436-022-07534-3 · 2022 · External reference
Designing heterodimeric two-stranded alpha-helical coiled-coils: the effect of chain length on protein folding, stability and specificity
10.1034/j.1399-3011.2001.10972.x · 2001 · External reference
iU-ExM: nanoscopy of organelles and tissues with iterative ultrastructure expansion microscopy
10.1038/s41467-023-43582-8 · 2023 · External reference
Identification of potent phosphodiesterase inhibitors that demonstrate cyclic nucleotide-dependent functions in apicomplexan parasites
10.1021/cb501004q · 2015 · External reference
Coupling auxin-inducible degron system with ultrastructure expansion microscopy to accelerate the discovery of gene function in Toxoplasma gondii.
10.1007/978-1-0716-1681-9_8 · 2021 · External reference
An Alveolata secretory machinery adapted to parasite host cell invasion
10.1038/s41564-020-00854-z · 2021 · External reference
A conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in Toxoplasma gondii
10.1038/s41467-017-02341-2 · 2017 · External reference
Biogenesis and secretion of micronemes in Toxoplasma gondii
10.1111/cmi.13018 · 2019 · External reference
Toxoplasma rhoptry protein 16 (ROP16) subverts host function by direct tyrosine phosphorylation of STAT6
10.1074/jbc.m110.112359 · 2010 · External reference
A druggable secretory protein maturase of Toxoplasma essential for invasion and egress
10.7554/elife.27480 · 2017 · External reference
Essential cGMP signaling in toxoplasma is initiated by a hybrid P-type ATPase-guanylate cyclase
10.1016/j.chom.2018.10.015 · 2018 · External reference
“Self-cleaving” 2A peptide from porcine teschovirus-1 mediates cleavage of dual fluorescent proteins in transgenic Eimeria tenella
10.1186/s13567-016-0351-z · 2016 · External reference
Cryptosporidium uses multiple distinct secretory organelles to interact with and modify its host cell
10.1016/j.chom.2023.03.001 · 2023 · External reference
Apicomplexans: a conoid ring unites them all
10.1371/journal.pbio.3001105 · 2021 · External reference
Molecular characterization of the conoid complex in Toxoplasma reveals its conservation in all apicomplexans, including Plasmodium species
10.1371/journal.pbio.3001081 · 2021 · External reference
Toxoplasma gondii HOOK-FTS-HIP complex is critical for secretory organelle discharge during motility, invasion, and egress
10.1128/mbio.00458-23 · 2023 · External reference
A Toxoplasma palmitoyl acyl transferase and the palmitoylated armadillo repeat protein TgARO govern apical rhoptry tethering and reveal a critical role for the rhoptries in host cell invasion but not egress
2013 · External reference
The Toxoplasma protein ARO mediates the apical positioning of rhoptry organelles, a prerequisite for host cell invasion
10.1016/j.chom.2013.02.001 · 2013 · External reference
Rhoptry secretion system structure and priming in Plasmodium falciparum revealed using in situ cryo-electron tomography
10.1038/s41564-022-01171-3 · 2022 · External reference
ToxoDB: functional genomics resource for toxoplasma and related organisms.
10.1007/978-1-4939-9857-9_2 · 2020 · External reference
EuPaGDT: a web tool tailored to design CRISPR guide RNAs for eukaryotic pathogens
2015 · External reference
Efficient genome engineering of Toxoplasma gondii using CRISPR/Cas9
10.1371/journal.pone.0100450 · 2014 · External reference
Transient transfection and expression in the obligate intracellular parasite Toxoplasma gondii
10.1126/science.8469986 · 1993 · External reference
Conditional knockdown of proteins using auxin-inducible degron (AID) fusions in Toxoplasma gondii
10.21769/bioprotoc.2728 · 2018 · External reference
A systematic screen to discover and analyze apicoplast proteins identifies a conserved and essential protein import factor
10.1371/journal.ppat.1002392 · 2011 · External reference
Real-time cryo-electron microscopy data preprocessing with Warp
10.1038/s41592-019-0580-y · 2019 · External reference
AreTomo: an integrated software package for automated marker-free, motion-corrected cryo-electron tomographic alignment and reconstruction
2022 · External reference
Computer visualization of three-dimensional image data using IMOD
10.1006/jsbi.1996.0013 · 1996 · External reference
UCSF ChimeraX: structure visualization for researchers, educators, and developers
10.1002/pro.3943 · 2021 · External reference
