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References from Amyloid precursor protein modulates cerebellar Purkinje cell activity and motor function through regulation of Nav1.6 currents. Local targets link to admitted publications; unresolved targets remain external evidence.
Synapse formation and function is modulated by the amyloid precursor protein
10.1523/jneurosci.1450-06.2006 · 2006 · External reference
A TAG1-APP signalling pathway through Fe65 negatively modulates neurogenesis
10.1038/ncb1690 · 2008 · External reference
APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP
10.1038/emboj.2011.119 · 2011 · External reference
Secreted amyloid-β precursor protein functions as a GABABR1a ligand to modulate synaptic transmission
2019 · External reference
Secreted amyloid precursor protein-alpha can restore novel object location memory and hippocampal LTP in aged rats
10.1016/j.nlm.2016.08.002 · 2017 · External reference
Mechanisms contributing to the deficits in hippocampal synaptic plasticity in mice lacking amyloid precursor protein
10.1016/s0028-3908(98)00204-4 · 1999 · External reference
Acute function of secreted amyloid precursor protein fragment APPsα in synaptic plasticity
10.1007/s00401-014-1368-x · 2015 · External reference
beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity
10.1016/0092-8674(95)90073-x · 1995 · External reference
The secreted beta-amyloid precursor protein ectodomain APPs alpha is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice
10.1523/jneurosci.1026-07.2007 · 2007 · External reference
Not just amyloid: physiological functions of the amyloid precursor protein family
10.1038/nrn.2017.29 · 2017 · External reference
Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-Like protein 2
10.1523/jneurosci.4660-04.2005 · 2005 · External reference
Physiology of the cerebellum
10.1016/b978-0-444-63956-1.00006-0 · 2018 · External reference
Genetic targeting of principal neurons in neocortex and hippocampus of NEX-Cre mice
10.1002/dvg.20256 · 2006 · External reference
The relationship between brain activity and peak grip force is modulated by corticospinal system integrity after subcortical stroke
10.1111/j.1460-9568.2007.05434.x · 2007 · External reference
The symptoms of acute cerebellar injuries due to gunshot injuries
10.1093/brain/40.4.461 · 1917 · External reference
Expression and distribution of voltage-gated sodium channels in the cerebellum
10.1080/14734220309424 · 2003 · External reference
Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy
10.1523/jneurosci.2162-07.2007 · 2007 · External reference
Altered subthreshold sodium currents and disrupted firing patterns in Purkinje neurons of Scn8a mutant mice
10.1016/s0896-6273(00)80969-1 · 1997 · External reference
Role of NaV1.6-mediated persistent sodium current and bursting-pacemaker properties in breathing rhythm generation
10.1016/j.celrep.2023.113000 · 2023 · External reference
Expressions of amyloid precursor protein, synaptophysin and presenilin-1 in the different areas of the developing cerebellum of rat
10.1016/s0197-0186(99)00108-4 · 2000 · External reference
Amyloid precursor protein enhances Nav1.6 sodium channel cell surface expression
10.1074/jbc.m114.617092 · 2015 · External reference
Selective transgene expression in cerebellar Purkinje cells and granule cells using adeno-associated viruses together with specific promoters
10.1016/j.brainres.2015.05.015 · 2015 · External reference
Minimal Purkinje cell-specific PCP2/L7 promoter virally available for rodents and non-human primates
10.1016/j.omtm.2017.07.006 · 2017 · External reference
Corticotropin-releasing hormone signaling from prefrontal cortex to lateral septum suppresses interaction with familiar mice
10.1016/j.cell.2023.08.010 · 2023 · External reference
Loss of cerebellar glutamate transporters EAAT4 and GLAST differentially affects the spontaneous firing pattern and survival of Purkinje cells
10.1093/hmg/ddy169 · 2018 · External reference
Complex spike wars: a new hope
10.1007/s12311-018-0960-3 · 2018 · External reference
The contribution of resurgent sodium current to high-frequency firing in Purkinje neurons: an experimental and modeling study
10.1523/jneurosci.23-12-04899.2003 · 2003 · External reference
Ant venoms contain vertebrate-selective pain-causing sodium channel toxins
10.1038/s41467-023-38839-1 · 2023 · External reference
Complex spike synchrony dependent modulation of rat deep cerebellar nuclear activity
10.7554/elife.40101 · 2019 · External reference
Quantitative histological analysis of the cerebellar nuclei in the cat. I. Numerical data on cells and on synapses
1977 · External reference
Postsynaptic targets of Purkinje cell terminals in the cerebellar and vestibular nuclei of the rat
10.1111/j.1460-9568.1995.tb00653.x · 1995 · External reference
Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein gene
10.1016/0092-8674(94)90066-3 · 1994 · External reference
Persistent Nav1.1 and Nav1.6 currents drive spinal locomotor functions through nonlinear dynamics
10.1016/j.celrep.2023.113085 · 2023 · External reference
Increased production of amyloid precursor protein provides a substrate for caspase-3 in dying motoneurons
10.1523/jneurosci.18-15-05869.1998 · 1998 · External reference
Purkinje cell representations of behavior: diary of a busy neuron
10.1177/1073858418785628 · 2019 · External reference
The cerebellum as a neuronal prosthesis machine
10.1016/s0079-6123(01)30020-1 · 2001 · External reference
Purkinje cell simple spike activity during grasping and lifting objects of different textures and weights
10.1152/jn.1990.64.3.698 · 1990 · External reference
What features of limb movements are encoded in the discharge of cerebellar neurons?
10.1007/s12311-010-0243-0 · 2011 · External reference
Dynorphin promotes stress-induced depressive behaviors by inhibiting ventral pallidal neurons in rats
2022 · External reference
A role for the cerebellum in motor-triggered alleviation of anxiety
2024 · External reference
FAM210A is a novel determinant of bone and muscle structure and strength
2018 · External reference
Suppression of microglial activation and monocyte infiltration ameliorates cerebellar hemorrhage induced-brain injury and ataxia
10.1016/j.bbi.2020.07.027 · 2020 · External reference
