Research graph
References from The novel GlcNAc 6-phosphate dehydratase NagS governs a metabolic checkpoint that controls nutrient signaling in Streptomyces. Local targets link to admitted publications; unresolved targets remain external evidence.
Bacterial solutions to multicellularity: a tale of biofilms, filaments and fruiting bodies
10.1038/nrmicro3178 · 2014 · External reference
10.1093/oso/9780195150667.001.0001
10.1093/oso/9780195150667.001.0001 · 2007 · External reference
Thoughts and facts about antibiotics: where we are now and where we are heading
10.1038/ja.2012.27 · 2012 · External reference
Taxonomy, physiology, and natural products of actinobacteria
10.1128/mmbr.00019-15 · 2015 · External reference
A morphological and genetic mapping study of bald colony mutants of Streptomyces coelicolor
10.1099/00221287-96-2-299 · 1976 · External reference
Extracellular complementation and the identification of additional genes involved in aerial mycelium formation in Streptomyces coelicolor
10.1093/genetics/151.2.569 · 1999 · External reference
Extracellular complementation of a developmental mutation implicates a small sporulation protein in aerial mycelium formation by S. coelicolor
10.1016/0092-8674(91)90096-h · 1991 · External reference
The SapB morphogen is a lantibiotic-like peptide derived from the product of the developmental gene ramS in Streptomyces coelicolor
10.1073/pnas.0404220101 · 2004 · External reference
Mutants of Streptomyces coelicolor defective in sporulation
10.1099/00221287-61-3-397 · 1970 · External reference
New sporulation loci in Streptomyces coelicolor A3(2)
10.1128/jb.181.17.5419-5425.1999 · 1999 · External reference
1995 Colworth Prize Lecture. The regulation of antibiotic production in Streptomyces coelicolor A3(2)
1996 · External reference
Regulation of antibiotic production in Actinobacteria: new perspectives from the post-genomic era
10.1039/c8np00012c · 2018 · External reference
Positive control of cell division: FtsZ is recruited by SsgB during sporulation of Streptomyces
10.1101/gad.600211 · 2011 · External reference
Constitutive expression of ftsZ overrides the whi developmental genes to initiate sporulation of Streptomyces coelicolor
10.1007/s10482-011-9678-7 · 2012 · External reference
DNA damage-induced block of sporulation in Streptomyces venezuelae involves downregulation of ssgB
2022 · External reference
A death round affecting a young compartmentalized mycelium precedes aerial mycelium dismantling in confluent surface cultures of Streptomyces antibioticus
10.1099/mic.0.28045-0 · 2005 · External reference
Production of prodiginines is part of a programmed cell death process in Streptomyces coelicolor
10.3389/fmicb.2018.01742 · 2018 · External reference
Feast or famine: the global regulator DasR links nutrient stress to antibiotic production by Streptomyces
10.1038/embor.2008.83 · 2008 · External reference
The sugar phosphotransferase system of Streptomyces coelicolor is regulated by the GntR-family regulator DasR and links N-acetylglucosamine metabolism to the control of development
10.1111/j.1365-2958.2006.05319.x · 2006 · External reference
Unsuspected control of siderophore production by N-acetylglucosamine in streptomycetes
10.1111/j.1758-2229.2012.00354.x · 2012 · External reference
Altered desferrioxamine-mediated iron utilization is a common trait of bald mutants of Streptomyces coelicolor
10.1039/c4mt00068d · 2014 · External reference
Genome-wide analysis of in vivo binding of the master regulator DasR in Streptomyces coelicolor identifies novel non-canonical targets
10.1371/journal.pone.0122479 · 2015 · External reference
Ecology and genomics of Actinobacteria: new concepts for natural product discovery
10.1038/s41579-020-0379-y · 2020 · External reference
Compendium of specialized metabolite biosynthetic diversity encoded in bacterial genomes
10.1038/s41564-022-01110-2 · 2022 · External reference
Intertwining nutrient-sensory networks and the control of antibiotic production in Streptomyces
10.1111/mmi.13464 · 2016 · External reference
Cracking the regulatory code of biosynthetic gene clusters as a strategy for natural product discovery
2018 · External reference
The phosphotransferase system of Streptomyces coelicolor is biased for N-acetylglucosamine metabolism
10.1128/jb.185.23.7019-7023.2003 · 2003 · External reference
Genes essential for morphological development and antibiotic production in Streptomyces coelicolor are targets of BldD during vegetative growth
10.1111/j.1365-2958.2010.07338.x · 2010 · External reference
Tetrameric c-di-GMP mediates effective transcription factor dimerization to control Streptomyces development
10.1016/j.cell.2014.07.022 · 2014 · External reference
Engineering of N-acetylglucosamine metabolism for improved antibiotic production in Streptomyces coelicolor A3(2) and an unsuspected role of NagA in glucosamine metabolism
10.4161/bioe.21371 · 2012 · External reference
Systems-wide analysis of the ROK-family regulatory gene rokL6 and its role in the control of glucosamine toxicity in Streptomyces coelicolor
2023 · External reference
The SIS domain: a phosphosugar-binding domain
10.1016/s0968-0004(99)01357-2 · 1999 · External reference
N-acetylmuramic acid 6-phosphate lyases (MurNAc etherases): role in cell wall metabolism, distribution, structure, and mechanism
10.1007/s00018-007-7399-x · 2008 · External reference
Crystal structure of YfeU protein from Haemophilus influenzae: a predicted etherase involved in peptidoglycan recycling
10.1007/s10969-009-9063-1 · 2009 · External reference
Characterization of a glucosamine/glucosaminide N-acetyltransferase of Clostridium acetobutylicum
10.1128/jb.05519-11 · 2011 · External reference
Cytotoxic and antibacterial marfuraquinocins from the deep South China Sea-derived Streptomyces niveus SCSIO 3406
10.1021/np4006025 · 2013 · External reference
A membrane-bound prenyltransferase catalyzes the O-prenylation of 1,6-dihydroxyphenazine in the marine bacterium Streptomyces sp. CNQ-509
10.1002/cbic.201402394 · 2014 · External reference
The STRING database in 2023: protein-protein association networks and functional enrichment analyses for any sequenced genome of interest
10.1093/nar/gkac1000 · 2023 · External reference
Transcriptional regulation of the desferrioxamine gene cluster of Streptomyces coelicolor is mediated by binding of DmdR1 to an iron box in the promoter of the desA gene
10.1111/j.1742-4658.2007.05662.x · 2007 · External reference
Genome mining based on transcriptional regulatory networks uncovers a novel locus involved in desferrioxamine biosynthesis
10.1371/journal.pbio.3003183 · 2025 · External reference
Thermal decomposition of β-D-galactopyranosyl-(1→ 3)-2-acetamido-2-deoxy-D-hexopyranoses under neutral conditions
10.1016/j.carres.2010.06.003 · 2010 · External reference
Structure and function of sedoheptulose-7-phosphate isomerase, a critical enzyme for lipopolysaccharide biosynthesis and a target for antibiotic adjuvants
10.1074/jbc.m706163200 · 2008 · External reference
Structure of MurNAc 6-phosphate hydrolase (MurQ) from Haemophilus influenzae with a bound inhibitor
10.1021/bi4010446 · 2013 · External reference
N-acetylglucosamine-6-phosphate deacetylase from Escherichia coli: purification and molecular and kinetic characterization
10.1006/abbi.1997.9780 · 1997 · External reference
Structural and functional determination of homologs of the Mycobacterium tuberculosis N-acetylglucosamine-6-phosphate deacetylase (NagA)
10.1074/jbc.ra118.002597 · 2018 · External reference
The crystal structure of mouse phosphoglucose isomerase at 1.6A resolution and its complex with glucose 6-phosphate reveals the catalytic mechanism of sugar ring opening
10.1016/j.jmb.2004.07.085 · 2004 · External reference
Anthracyclines: biosynthesis, engineering and clinical applications
10.1039/d1np00059d · 2022 · External reference
Unresolved reference
1989 · External reference
Analysis of Streptomyces avermitilis genes required for avermectin biosynthesis utilizing a novel integration vector
10.1016/0378-1119(92)90603-m · 1992 · External reference
Unresolved reference
2000 · External reference
Streptomyces coelicolor
10.1016/j.tim.2018.12.008 · 2019 · External reference
Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp
10.1016/0378-1119(92)90627-2 · 1992 · External reference
Cloning of genes governing the deoxysugar portion of the erythromycin biosynthesis pathway in Saccharopolyspora erythraea (Streptomyces erythreus)
10.1128/jb.171.11.5872-5881.1989 · 1989 · External reference
GlcP constitutes the major glucose uptake system of Streptomyces coelicolor A3(2)
10.1111/j.1365-2958.2004.04413.x · 2005 · External reference
Functional expression of the Cre recombinase in actinomycetes
10.1007/s00253-008-1382-9 · 2008 · External reference
Functional analysis of the N-acetylglucosamine metabolic genes of Streptomyces coelicolor and role in control of development and antibiotic production
10.1128/jb.06370-11 · 2012 · External reference
Expression of Cre recombinase during transient phage infection permits efficient marker removal in Streptomyces
10.1093/nar/gnj019 · 2006 · External reference
Enzymatic assembly of DNA molecules up to several hundred kilobases
10.1038/nmeth.1318 · 2009 · External reference
Integrative vectors for heterologous gene expression in Streptomyces spp
10.1016/0378-1119(95)00191-8 · 1995 · External reference
Structural analysis of N-acetylglucosamine-6-phosphate deacetylase apoenzyme from Escherichia coli
10.1016/j.jmb.2006.03.024 · 2006 · External reference
N-Acetyl-D-glucosamine-6-phosphate deacetylase: substrate activation via a single divalent metal ion
10.1021/bi700543x · 2007 · External reference
Protein database searches using compositionally adjusted substitution matrices
10.1111/j.1742-4658.2005.04945.x · 2005 · External reference
MEGA11: molecular evolutionary genetics analysis version 11
10.1093/molbev/msab120 · 2021 · External reference
SyntTax: a web server linking synteny to prokaryotic taxonomy
10.1186/1471-2105-14-4 · 2013 · External reference
FastTree 2–approximately maximum-likelihood trees for large alignments
10.1371/journal.pone.0009490 · 2010 · External reference
Glucose kinase of Streptomyces coelicolor A3(2): large-scale purification and biochemical analysis
10.1023/a:1010234916745 · 2000 · External reference
Integration, scaling, space-group assignment and post-refinement
10.1107/s0907444909047374 · 2010 · External reference
How good are my data and what is the resolution?
10.1107/s0907444913000061 · 2013 · External reference
DIALS: implementation and evaluation of a new integration package
10.1107/s2059798317017235 · 2018 · External reference
Coot: model-building tools for molecular graphics
10.1107/s0907444904019158 · 2004 · External reference
Features and development of Coot
10.1107/s0907444910007493 · 2010 · External reference
PHENIX: a comprehensive Python-based system for macromolecular structure solution
10.1107/s0907444909052925 · 2010 · External reference
Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery
10.1016/j.ab.2004.04.031 · 2004 · External reference
