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References from The luminal ring protein C2CD3 acts as a radial in-to-out organizer of the distal centriole and appendages. Local targets link to admitted publications; unresolved targets remain external evidence.
HsSAS-6-dependent cartwheel assembly ensures stabilization of centriole intermediates
2019 · External reference
Regulated HsSAS-6 levels ensure formation of a single procentriole per centriole during the centrosome duplication cycle
10.1016/j.devcel.2007.07.004 · 2007 · External reference
SAS-6 defines a protein family required for centrosome duplication in C. elegans and in human cells
10.1038/ncb1220 · 2005 · External reference
Structural basis of the 9-fold symmetry of centrioles
10.1016/j.cell.2011.01.008 · 2011 · External reference
Structures of SAS-6 suggest its organization in centrioles
10.1126/science.1199325 · 2011 · External reference
WDR90 is a centriolar microtubule wall protein important for centriole architecture integrity
10.7554/elife.57205 · 2020 · External reference
A helical inner scaffold provides a structural basis for centriole cohesion
10.1126/sciadv.aaz4137 · 2020 · External reference
Cep164, a novel centriole appendage protein required for primary cilium formation
10.1083/jcb.200707181 · 2007 · External reference
Centriole distal appendages promote membrane docking, leading to cilia initiation
10.1101/gad.207043.112 · 2013 · External reference
A ciliopathy complex builds distal appendages to initiate ciliogenesis
10.1083/jcb.202011133 · 2021 · External reference
Overview of the centriole architecture
10.1016/j.sbi.2020.09.015 · 2021 · External reference
Super-resolution architecture of mammalian centriole distal appendages reveals distinct blade and matrix functional components
10.1038/s41467-018-04469-1 · 2018 · External reference
The evolutionary conserved proteins CEP90, FOPNL, and OFD1 recruit centriolar distal appendage proteins to initiate their assembly
10.1371/journal.pbio.3001782 · 2022 · External reference
C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals
10.1073/pnas.1318737111 · 2014 · External reference
A distal centriolar protein network controls organelle maturation and asymmetry
10.1038/s41467-018-06286-y · 2018 · External reference
The oral-facial-digital syndrome gene C2CD3 encodes a positive regulator of centriole elongation
10.1038/ng.3031 · 2014 · External reference
Time-series reconstruction of the molecular architecture of human centriole assembly
10.1016/j.cell.2024.03.025 · 2024 · External reference
Single-molecule localization microscopy reveals the ultrastructural constitution of distal appendages in expanded mammalian centrioles
10.1038/s41467-023-37342-x · 2023 · External reference
Molecular resolution imaging by post-labeling expansion single-molecule localization microscopy (Ex-SMLM)
10.1038/s41467-020-17086-8 · 2020 · External reference
The three-dimensional structure of the basal body from the rhesus monkey oviduct
10.1083/jcb.54.2.246 · 1972 · External reference
Centrioles in the cell cycle. I. Epithelial cells
10.1083/jcb.93.3.938 · 1982 · External reference
ELI trifocal microscope: a precise system to prepare target cryo-lamellae for in situ cryo-ET study
10.1038/s41592-022-01748-0 · 2023 · External reference
Integrated multimodality microscope for accurate and efficient target-guided cryo-lamellae preparation
10.1038/s41592-022-01749-z · 2023 · External reference
Evolutionary conservation of centriole rotational asymmetry in the human centrosome
10.7554/elife.72382 · 2022 · External reference
iU-ExM: nanoscopy of organelles and tissues with iterative ultrastructure expansion microscopy
10.1038/s41467-023-43582-8 · 2023 · External reference
The connecting cilium inner scaffold provides a structural foundation that protects against retinal degeneration
10.1371/journal.pbio.3001649 · 2022 · External reference
The ultrastructure of centriole in mammalian tissue culture cells
10.1016/0309-1651(80)90177-0 · 1980 · External reference
Cep97 and CP110 suppress a cilia assembly program
10.1016/j.cell.2007.06.027 · 2007 · External reference
CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base
10.1038/ncb2739 · 2013 · External reference
Human SFI1 and Centrin form a complex critical for centriole architecture and ciliogenesis
10.15252/embj.2022112107 · 2022 · External reference
SAS-1 is a C2 domain protein critical for centriole integrity in C. elegans
10.1371/journal.pgen.1004777 · 2014 · External reference
Control of centriole length by CPAP and CP110
10.1016/j.cub.2009.05.016 · 2009 · External reference
Cep97 is required for centriole structural integrity and cilia formation in Drosophila
10.1016/j.cub.2020.05.078 · 2020 · External reference
Overview of the centriole architecture
10.1016/j.sbi.2020.09.015 · 2021 · External reference
Structure of the SAS-6 cartwheel hub from Leishmania major
10.7554/elife.01812 · 2014 · External reference
Structures of SAS-6 suggest its organization in centrioles
10.1126/science.1199325 · 2011 · External reference
Cell-free reconstitution reveals centriole cartwheel assembly mechanisms
10.1038/ncomms14813 · 2017 · External reference
Structural insights into SSNA1 self-assembly and its microtubule binding for centriole maintenance
2024 · External reference
SAS-1 is a C2 domain protein critical for centriole integrity in C. elegans
10.1371/journal.pgen.1004777 · 2014 · External reference
The ultrastructure of the Chlamydomonas reinhardtii basal apparatus: identification of an early marker of radial asymmetry inherent in the basal body
10.1242/jcs.01120 · 2004 · External reference
Centrin scaffold in Chlamydomonas reinhardtii revealed by immunoelectron microscopy
10.1128/ec.4.7.1253-1263.2005 · 2005 · External reference
C. elegans SSNA-1 is required for the structural integrity of centrioles and bipolar spindle assembly
10.1038/s41467-025-59939-0 · 2025 · External reference
C. elegans SAS-1 ensures centriole integrity and ciliary function, and operates with SSNA-1
2025 · External reference
Unresolved reference
2025 · External reference
Chlamydomonas DIP13 and human NA14: a new class of proteins associated with microtubule structures is involved in cell division
10.1242/jcs.00337 · 2003 · External reference
An evolutionarily conserved SSNA1/DIP13 homologue is a component of both basal and apical complexes of Toxoplasma gondii
10.1038/srep27809 · 2016 · External reference
A SAS-6-like protein suggests that the Toxoplasma conoid complex evolved from flagellar components
10.1128/ec.00096-13 · 2013 · External reference
Mutations in human C2CD3 cause skeletal dysplasia and provide new insights into phenotypic and cellular consequences of altered C2CD3 function
10.1038/srep24083 · 2016 · External reference
Centriolar protein C2cd3 is required for craniofacial development
10.3389/fcell.2021.647391 · 2021 · External reference
Characterization of three ciliopathy pedigrees expands the phenotype associated with biallelic C2CD3 variants
10.1038/s41431-018-0222-3 · 2018 · External reference
NA14 is a novel nuclear autoantigen with a coiled-coil domain
10.1074/jbc.273.3.1634 · 1998 · External reference
Architecture of the centriole cartwheel‐containing region revealed by cryo‐electron tomography
10.15252/embj.2020106246 · 2020 · External reference
In situ architecture of the ciliary base reveals the stepwise assembly of intraflagellar transport trains
10.1126/science.abm6704 · 2022 · External reference
10.1101/2024.10.04.616628
10.1101/2024.10.04.616628 · 2024 · External reference
Microtubules in Asgard archaea
10.1016/j.cell.2025.02.027 · 2025 · External reference
Integrating cellular electron microscopy with multimodal data to explore biology across space and time
10.1016/j.cell.2024.01.005 · 2024 · External reference
Imaging cellular ultrastructures using expansion microscopy (U-ExM)
10.1038/s41592-018-0238-1 · 2019 · External reference
WDR90 is a centriolar microtubule wall protein important for centriole architecture integrity
10.7554/elife.57205 · 2020 · External reference
The evolutionary conserved proteins CEP90, FOPNL, and OFD1 recruit centriolar distal appendage proteins to initiate their assembly
10.1371/journal.pbio.3001782 · 2022 · External reference
Fine-tuning FAM161A gene augmentation therapy to restore retinal function
10.1038/s44321-024-00053-x · 2024 · External reference
Serialized on-grid lift-in sectioning for tomography (SOLIST) enables a biopsy at the nanoscale
10.1038/s41592-024-02384-6 · 2024 · External reference
10.1038/s41467-025-66410-7
10.1038/s41467-025-66410-7 · 2025 · External reference
Content-aware image restoration for electron microscopy
10.1016/bs.mcb.2019.05.001 · 2019 · External reference
Mind the gap: Micro-expansion joints drastically decrease the bending of FIB-milled cryo-lamellae
10.1016/j.jsb.2019.09.006 · 2019 · External reference
Implementation of a cryo-electron tomography tilt-scheme optimized for high resolution subtomogram averaging
10.1016/j.jsb.2016.06.007 · 2017 · External reference
TOMOMAN: a software package for large-scale cryo-electron tomography data preprocessing, community data sharing and collaborative computing
10.1107/s1600576724010264 · 2024 · External reference
10.1109/isbi.2019.8759519
10.1109/isbi.2019.8759519 · External reference
Isotropic reconstruction for electron tomography with deep learning
10.1038/s41467-022-33957-8 · 2022 · External reference
STOPGAP, an open-source package for template matching, subtomogram alignment, and classification
2023 · External reference
