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References from The master virulence regulator PhoP dictates carbon metabolism by controlling cyclic AMP synthesis in Salmonella. Local targets link to admitted publications; unresolved targets remain external evidence.
Glucose inhibition and the diauxie phenomenon
10.1073/pnas.45.10.1494 · 1959 · External reference
Cytoplasmic Mg2+ supersedes carbon source preference to dictate Salmonella metabolism
10.1073/pnas.2424337122 · 2025 · External reference
A pathogen-specific isotope tracing approach reveals metabolic activities and fluxes of intracellular Salmonella
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Parallel exploitation of diverse host nutrients enhances Salmonella virulence
10.1371/journal.ppat.1003301 · 2013 · External reference
Host resistance factor SLC11A1 restricts Salmonella growth through magnesium deprivation
10.1126/science.aax7898 · 2019 · External reference
Human variation impacting MCOLN2 restricts Salmonella Typhi replication by magnesium deprivation
10.1016/j.xgen.2023.100290 · 2023 · External reference
Reducing ribosome biosynthesis promotes translation during low Mg2+ stress
10.1016/j.molcel.2016.05.008 · 2016 · External reference
Chaperone Hsp70 helps Salmonella survive infection-relevant stress by reducing protein synthesis
10.1371/journal.pbio.3002560 · 2024 · External reference
The E. coli cyclic AMP receptor protein.
10.1007/978-3-642-79488-9_9 · 1995 · External reference
How the PhoP/PhoQ system controls virulence and Mg2+ homeostasis: lessons in signal transduction, pathogenesis, physiology, and evolution
10.1128/mmbr.00176-20 · 2021 · External reference
Mg2+ as an extracellular signal: environmental regulation of Salmonella virulence
10.1016/s0092-8674(00)81003-x · 1996 · External reference
Acidic pH sensing in the bacterial cytoplasm is required for Salmonella virulence
10.1111/mmi.13439 · 2016 · External reference
Cationic antimicrobial peptides serve as activation signals for the Salmonella Typhimurium PhoPQ and PmrAB regulons in vitro and in vivo
10.3389/fcimb.2012.00102 · 2012 · External reference
MgtA and MgtB: prokaryotic P-type ATPases that mediate Mg2+ influx
10.1007/bf00768852 · 1992 · External reference
A bacterial virulence protein promotes pathogenicity by inhibiting the bacterium’s own F1Fo ATP synthase
10.1016/j.cell.2013.06.004 · 2013 · External reference
Limitation of phosphate assimilation maintains cytoplasmic magnesium homeostasis
10.1073/pnas.2021370118 · 2021 · External reference
Signal-specific temporal response by the Salmonella PhoP/PhoQ regulatory system
10.1111/mmi.12449 · 2014 · External reference
Sequestration from protease adaptor confers differential stability to protease substrate
10.1016/j.molcel.2017.03.009 · 2017 · External reference
The Salmonella selC locus contains a pathogenicity island mediating intramacrophage survival
10.1093/emboj/16.17.5376 · 1997 · External reference
Small proteins regulate Salmonella survival inside macrophages by controlling degradation of a magnesium transporter
10.1073/pnas.2006116117 · 2020 · External reference
cAMP receptor protein-cAMP plays a crucial role in glucose-lactose diauxie by activating the major glucose transporter gene in Escherichia coli
10.1073/pnas.94.24.12914 · 1997 · External reference
Sites of allosteric shift in the structure of the cyclic AMP receptor protein
10.1016/s0092-8674(85)80055-6 · 1985 · External reference
Structure and regulation of the glpFK operon encoding glycerol diffusion facilitator and glycerol kinase of Escherichia coli K-12.
10.1016/s0021-9258(18)42670-1 · 1992 · External reference
Positive and negative transcriptional regulation of the Escherichia coli gluconate regulon gene gntT by GntR and the cyclic AMP (cAMP)-cAMP receptor protein complex
10.1128/jb.180.7.1777-1785.1998 · 1998 · External reference
Limited impact of Salmonella stress and persisters on antibiotic clearance
10.1038/s41586-024-08506-6 · 2025 · External reference
Slow growth determines nonheritable antibiotic resistance in Salmonella enterica
10.1126/scisignal.aax3938 · 2019 · External reference
How bacterial pathogens coordinate appetite with virulence
10.1128/mmbr.00198-22 · 2023 · External reference
Some properties of Escherichia coli adenyl cyclase
10.1016/0003-9861(70)90127-x · 1970 · External reference
Isolation of adenyl cyclase from Escherichia coli
10.1073/pnas.63.1.86 · 1969 · External reference
Characterization of adenylate cyclase from Escherichia coli
10.1007/bf02876688 · 1980 · External reference
Cellular adaptations to cytoplasmic Mg2+ limitation
10.1146/annurev-micro-020518-115606 · 2021 · External reference
Glycerol and methylglyoxal metabolism
10.1128/ecosalplus.3.4.3 · 2005 · External reference
Salmonella-regulated lipopolysaccharide modifications.
2010 · External reference
The biosynthesis of gram-negative endotoxin. Formation of lipid A precursors from UDP-GlcNAc in extracts of Escherichia coli
10.1016/s0021-9258(17)36289-0 · 1985 · External reference
Assembly of bacterial surface glycopolymers as an antibiotic target
10.1007/s12275-023-00032-w · 2023 · External reference
Purification and characterization of adenylate cyclase from Escherichia coli K12.
10.1016/s0021-9258(18)32728-5 · 1983 · External reference
Magnesium and cell energetics: at the junction of metabolism of adenylate and non-adenylate nucleotides
10.1016/j.jplph.2022.153901 · 2023 · External reference
The glycolytic flux in Escherichia coli is controlled by the demand for ATP
10.1128/jb.184.14.3909-3916.2002 · 2002 · External reference
Studies of the distribution of Escherichia coli cAMP-receptor protein and RNA polymerase along the E. coli chromosome
10.1073/pnas.0506687102 · 2005 · External reference
Regulation of glpD and glpE gene expression by a cyclic AMP-cAMP receptor protein (cAMP-CRP) complex in Escherichia coli
10.1016/0167-4781(91)90149-g · 1991 · External reference
Multiple regulatory elements for the glpA operon encoding anaerobic glycerol-3-phosphate dehydrogenase and the glpD operon encoding aerobic glycerol-3-phosphate dehydrogenase in Escherichia coli: further characterization of respiratory control
10.1128/jb.172.1.179-184.1990 · 1990 · External reference
Interaction at a distance between multiple operators controls the adjacent, divergently transcribed glpTQ-glpACB operons of Escherichia coli K-12
10.1016/s0021-9258(18)42669-5 · 1992 · External reference
Purification and characterization of the repressor for the sn-glycerol 3-phosphate regulon of Escherichia coli K12
10.1016/s0021-9258(18)47669-7 · 1987 · External reference
Cyclic adenosine monophosphate in bacteria
10.1126/science.169.3943.339 · 1970 · External reference
Glucose-lactose diauxie in Escherichia coli
10.1128/jb.93.4.1397-1401.1967 · 1967 · External reference
Emergence of diauxie as an optimal growth strategy under resource allocation constraints in cellular metabolism
10.1073/pnas.2013836118 · 2021 · External reference
Regulation underlying hierarchical and simultaneous utilization of carbon substrates by flux sensors in Escherichia coli
10.1038/s41564-019-0610-7 · 2020 · External reference
The growth of bacterial cultures
1949 · External reference
Mechanism responsible for glucose-lactose diauxie in Escherichia coli: challenge to the cAMP model
10.1046/j.1365-2443.1996.24025.x · 1996 · External reference
Learning new tricks from an old dog: MalT of the Escherichia coli maltose system is part of a complex regulatory network
10.1016/s0168-9525(00)02086-2 · 2000 · External reference
Temporal evolution of master regulator Crp identifies pyrimidines as catabolite modulator factors
10.1038/s41467-021-26098-x · 2021 · External reference
Action of CAP on the malT promoter in vitro
10.1128/jb.156.3.1135-1143.1983 · 1983 · External reference
Negative transcriptional regulation of a positive regulator: the expression of malT, encoding the transcriptional activator of the maltose regulon of Escherichia coli, is negatively controlled by Mlc
10.1046/j.1365-2958.1998.00694.x · 1998 · External reference
FEDS: a novel fluorescence-based high-throughput method for measuring DNA supercoiling in vivo
10.1128/mbio.01053-20 · 2020 · External reference
Salmonella promotes virulence by repressing cellulose production
10.1073/pnas.1500989112 · 2015 · External reference
Molecular basis of the magnesium deprivation response in Salmonella typhimurium: identification of PhoP-regulated genes
10.1128/jb.178.17.5092-5099.1996 · 1996 · External reference
Dynamics of intracellular bacterial replication at the single cell level
10.1073/pnas.1000041107 · 2010 · External reference
Phenotypic variation of Salmonella in host tissues delays eradication by antimicrobial chemotherapy
10.1016/j.cell.2014.06.045 · 2014 · External reference
A synthetic medium for propagation and maintenance of virulent strains of Salmonella pullorum
10.3382/ps.0341283 · 1955 · External reference
Growth curves of Salmonella pullorum in different media
10.1128/jb.65.1.69-74.1953 · 1953 · External reference
Dual RNA-seq unveils noncoding RNA functions in host-pathogen interactions
10.1038/nature16547 · 2016 · External reference
Restoring global gene regulation through experimental evolution uncovers a NAP (Nucleoid-Associated Protein)-like behavior of Crp/Cap
2021 · External reference
Identification of the cpdA gene encoding cyclic 3’,5’-adenosine monophosphate phosphodiesterase in Escherichia coli
10.1074/jbc.271.41.25423 · 1996 · External reference
Cellular levels, excretion, and synthesis rates of cyclic AMP in Escherichia coli grown in continuous culture
10.1128/jb.149.3.801-807.1982 · 1982 · External reference
Mycobacterium tuberculosis PhoP integrates stress response to intracellular survival by regulating cAMP level
2024 · External reference
This is not your mother’s repressor: the complex role of fur in pathogenesis
10.1128/iai.00116-09 · 2009 · External reference
Intracellular cyclic AMP concentration is decreased in Salmonella typhimurium fur mutants
10.1099/00221287-148-4-1039 · 2002 · External reference
Magnesium is required for specific DNA binding of the CREB B-ZIP domain
10.1093/nar/30.5.1240 · 2002 · External reference
ATP as a biological hydrotrope
10.1126/science.aaf6846 · 2017 · External reference
The regulation of ribosomal RNA synthesis and bacterial cell growth
10.1007/bf00276469 · 1994 · External reference
Ribonucleic acid composition of bacteria as a function of growth rate
10.1016/s0022-2836(66)80248-6 · 1966 · External reference
Combined transcriptomic and metabolomic analysis of Salmonella in the presence or absence of PhoP-PhoQ system under low Mg2+ conditions
10.1007/s11306-022-01946-z · 2022 · External reference
Bacterial metabolic state more accurately predicts antibiotic lethality than growth rate
10.1038/s41564-019-0536-0 · 2019 · External reference
The role of bacterial metabolism in antimicrobial resistance
10.1038/s41579-025-01155-0 · 2025 · External reference
A broadly applicable, stress-mediated bacterial death pathway regulated by the phosphotransferase system (PTS) and the cAMP-Crp cascade
10.1073/pnas.2118566119 · 2022 · External reference
Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent
10.1073/pnas.83.14.5189 · 1986 · External reference
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
10.1073/pnas.120163297 · 2000 · External reference
Magnesium transport in Salmonella typhimurium. Regulation of mgtA and mgtB expression
10.1016/s0021-9258(17)35247-x · 1991 · External reference
Microcystin-LR does not induce alterations to transcriptomic or metabolomic profiles of a model heterotrophic bacterium
10.1371/journal.pone.0189608 · 2017 · External reference
A cross-platform toolkit for mass spectrometry and proteomics
10.1038/nbt.2377 · 2012 · External reference
El-MAVEN: a fast, robust, and user-friendly mass spectrometry data processing engine for metabolomics
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Using MetaboAnalyst 5.0 for LC-HRMS spectra processing, multi-omics integration and covariate adjustment of global metabolomics data
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