Research graph
References from Regional signaling controls stem cell-mediated regeneration in an invertebrate chordate. Local targets link to admitted publications; unresolved targets remain external evidence.
The cellular basis for animal regeneration
10.1016/j.devcel.2011.06.016 · 2011 · External reference
Insights into regeneration tool box: An animal model approach
10.1016/j.ydbio.2019.04.006 · 2019 · External reference
Advances in understanding tissue regenerative capacity and mechanisms in animals
10.1038/nrg2879 · 2010 · External reference
To regenerate or not to regenerate: Vertebrate model organisms of regeneration-competency and -incompetency
10.1111/wrr.13000 · 2022 · External reference
The ascidian as a model organism in developmental and evolutionary biology
10.1016/s0092-8674(01)00481-0 · 2001 · External reference
Cellular and molecular mechanisms of regeneration in colonial and solitary Ascidians
10.1016/j.ydbio.2018.11.021 · 2019 · External reference
Sexual and asexual development: two distinct programs producing the same tunicate
10.1016/j.celrep.2020.108681 · 2021 · External reference
Current knowledge on stem cells in ascidians
2010 · External reference
Progenitor targeting by adult stem cells in Ciona homeostasis, injury, and regeneration
10.1016/j.ydbio.2018.09.005 · 2019 · External reference
Differentially expressed chaperone genes reveal a stress response required for unidirectional regeneration in the basal chordate Ciona
10.1186/s12915-023-01633-y · 2023 · External reference
Closing the wounds: one hundred and twenty five years of regenerative biology in the ascidian Ciona intestinalis
10.1002/dvg.22799 · 2015 · External reference
Candidate stem cell isolation and transplantation in Hexacorallia
10.1016/j.celrep.2024.114944 · 2024 · External reference
Complex mammalian-like haematopoietic system found in a colonial chordate
10.1038/s41586-018-0783-x · 2018 · External reference
The interstitial stem cells in Hydractinia and their role in regeneration
10.1016/j.gde.2016.06.006 · 2016 · External reference
Stem cell systems and regeneration in planaria
10.1007/s00427-012-0426-4 · 2013 · External reference
Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activity
10.1073/pnas.96.16.9118 · 1999 · External reference
Assessment of aldehyde dehydrogenase in viable cells
10.1182/blood.v85.10.2742.bloodjournal85102742 · 1995 · External reference
Stem cells are units of natural selection in a colonial ascidian
10.1016/j.cell.2005.10.026 · 2005 · External reference
RNA exosome ribonuclease DIS3 degrades Pou6f1 to promote mouse pre-implantation cell differentiation
10.1016/j.celrep.2023.112047 · 2023 · External reference
myc maintains embryonic stem cell pluripotency and self-renewal
10.1016/j.diff.2010.05.001 · 2010 · External reference
Characterization of murine CD34, a marker for hematopoietic progenitor and stem cells
10.1182/blood.v84.3.691.691 · 1994 · External reference
Ddx56 maintains proliferation of mouse embryonic stem cells via ribosome assembly and interaction with the Oct4/Sox2 complex
10.1186/s13287-020-01800-w · 2020 · External reference
DDX56 promotes EMT and cancer stemness via MELK-FOXM1 axis in hepatocellular carcinoma
10.1016/j.isci.2024.109827 · 2024 · External reference
The DEAD-box helicase DDX56 is a conserved stemness regulator in normal and cancer stem cells
10.1016/j.celrep.2021.108903 · 2021 · External reference
Alpl prevents bone ageing sensitivity by specifically regulating senescence and differentiation in mesenchymal stem cells
10.1038/s41413-018-0029-4 · 2018 · External reference
Alkaline phosphatase in stem cells
10.1155/2015/628368 · 2015 · External reference
The tetraspanin CD53 protects stressed hematopoietic stem cells via promotion of DREAM complex-mediated quiescence
10.1182/blood.2022016929 · 2023 · External reference
Stem cells: units of development, units of regeneration, and units in evolution
10.1016/s0092-8674(00)81692-x · 2000 · External reference
Distal regeneration involves the age dependent activity of branchial sac stem cells in the ascidian Ciona intestinalis
10.1002/reg2.26 · 2015 · External reference
Wound-induced cell proliferation during animal regeneration
10.1002/wdev.321 · 2018 · External reference
Gli1 regulates the proliferation and differentiation of HSCs and myeloid progenitors
10.1182/blood-2009-09-241703 · 2010 · External reference
CNBP: a multifunctional nucleic acid chaperone involved in cell death and proliferation control
10.1002/iub.379 · 2010 · External reference
KNTC1 knockdown suppresses cell proliferation of colon cancer
10.1007/s13205-021-02800-0 · 2021 · External reference
Heat-shock protein protection
10.1016/s0166-2236(98)01392-7 · 1999 · External reference
Role of α-crystallin B in regulation of stress induced cardiomyocyte apoptosis
10.2174/1871525713666150123151731 · 2014 · External reference
Characterization of the deubiquitinating activity of USP19 and its role in endoplasmic reticulum-associated degradation
10.1074/jbc.m113.538934 · 2014 · External reference
The CASTOR proteins are arginine sensors for the mTORC1 pathway
10.1016/j.cell.2016.02.035 · 2016 · External reference
mTOR signaling at a glance
10.1242/jcs.051011 · 2009 · External reference
Metabolic regulation of cell growth and proliferation
10.1038/s41580-019-0123-5 · 2019 · External reference
TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
10.1084/jem.20081297 · 2008 · External reference
Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis
10.1523/jneurosci.3095-08.2009 · 2009 · External reference
Insulin signaling and its application
10.3389/fendo.2023.1226655 · 2023 · External reference
Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention
10.1038/sj.leu.2402945 · 2003 · External reference
BMP signalling in skeletal development, disease and repair
10.1038/nrendo.2016.12 · 2016 · External reference
BMP signaling in axon regeneration
10.1016/j.conb.2014.03.009 · 2014 · External reference
Matrix remodeling by MMPs during wound repair
10.1016/j.matbio.2015.03.002 · 2015 · External reference
Role of gelatinases MMP-2 and MMP-9 in tissue remodeling following acute lung injury
10.1590/s0100-879x2000000700004 · 2000 · External reference
Sox6, jack of all trades: a versatile regulatory protein in vertebrate development
10.1002/dvdy.22639 · 2011 · External reference
The role of Hox genes during vertebrate limb development
10.1016/j.gde.2007.05.011 · 2007 · External reference
The JAK/STAT signaling pathway
10.1242/jcs.00963 · 2004 · External reference
The JAK/STAT signaling pathway: from bench to clinic
10.1038/s41392-021-00791-1 · 2021 · External reference
JAK/STAT signaling coordinates stem cell proliferation and multilineage differentiation in the Drosophila intestinal stem cell lineage
10.1016/j.ydbio.2009.10.045 · 2010 · External reference
Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development
10.1083/jcb.200610046 · 2007 · External reference
Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis
10.3109/10799893.2015.1030412 · 2015 · External reference
Reparative inflammation takes charge of tissue regeneration
10.1038/nature17039 · 2016 · External reference
Macrophages in skin injury and repair
10.1016/j.imbio.2011.01.001 · 2011 · External reference
Macrophages in tissue repair, regeneration, and fibrosis
10.1016/j.immuni.2016.02.015 · 2016 · External reference
Functional characterization of hexacorallia phagocytic cells
10.3389/fimmu.2021.662803 · 2021 · External reference
Phagocyte dynamics in a highly regenerative urochordate: insights into development and host defense
10.1016/j.ydbio.2012.11.006 · 2013 · External reference
PAK1 silencing attenuated proinflammatory macrophage activation and foam cell formation by increasing PPARγ expression
10.1155/2021/6957900 · 2021 · External reference
Signaling pathways in phagocytosis
10.1002/(sici)1521-1878(199905)21:5<422::aid-bies9>3.0.co;2-# · 1999 · External reference
Identification of IRF-8 and IRF-1 target genes in activated macrophages
10.1016/j.molimm.2006.02.026 · 2007 · External reference
Nrf2-mediated anti-inflammatory polarization of macrophages as therapeutic targets for osteoarthritis
10.3389/fimmu.2022.967193 · 2022 · External reference
The lipid-modifying enzyme SMPDL3B negatively regulates innate immunity
10.1016/j.celrep.2015.05.006 · 2015 · External reference
Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription
10.1038/ncomms11624 · 2016 · External reference
An overview of Nrf2 signaling pathway and its role in inflammation
10.3390/molecules25225474 · 2020 · External reference
Macrophage nuclear receptors: Emerging key players in infectious diseases
10.1371/journal.ppat.1007585 · 2019 · External reference
IAPs, regulators of innate immunity and inflammation
10.1016/j.semcdb.2014.03.035 · 2015 · External reference
Systemic cell cycle activation is induced following complex tissue injury in axolotl
10.1016/j.ydbio.2017.07.010 · 2018 · External reference
Planarian regeneration involves distinct stem cell responses to wounds and tissue absence
10.1016/j.ydbio.2010.06.017 · 2010 · External reference
Hallmarks of regeneration
10.1016/j.stem.2024.07.007 · 2024 · External reference
The blastema and epimorphic regeneration in mammals
10.1016/j.ydbio.2017.08.007 · 2018 · External reference
The cellular and signaling dynamics of salamander limb regeneration
10.1016/j.ceb.2021.07.010 · 2021 · External reference
Differentiated skeletal cells contribute to blastema formation during zebrafish fin regeneration
10.1242/dev.064717 · 2011 · External reference
Integrin-Alpha-6+ Cells Are Responsible for Blastema Formation During Oral Siphon Regeneration in Ciona robusta
2025 · External reference
Evolution of the chordate regeneration blastema: Differential gene expression and conserved role of notch signaling during siphon regeneration in the ascidian Ciona
10.1016/j.ydbio.2015.07.017 · 2015 · External reference
Mesenchymal stem cell migration and tissue repair
10.3390/cells8080784 · 2019 · External reference
Neural signaling contributes to heart formation and growth in the invertebrate chordate, Ciona robusta
10.1371/journal.pbio.3003715 · 2026 · External reference
Regulation of adult stem cell quiescence and its functions in the maintenance of tissue integrity
10.1038/s41580-022-00568-6 · 2023 · External reference
Mechanisms, hallmarks, and implications of stem cell quiescence
10.1016/j.stemcr.2019.05.012 · 2019 · External reference
Reactivating head regrowth in a regeneration-deficient planarian species
10.1038/nature12414 · 2013 · External reference
Senescence-induced cellular reprogramming drives cnidarian whole-body regeneration
10.1016/j.celrep.2023.112687 · 2023 · External reference
EvoRegen in animals: Time to uncover deep conservation or convergence of adult stem cell evolution and regenerative processes
10.1016/j.ydbio.2017.10.010 · 2018 · External reference
Acute stress is detrimental to heart regeneration in zebrafish
10.1098/rsob.160012 · 2016 · External reference
A generic and cell-type-specific wound response precedes regeneration in planarians
10.1016/j.devcel.2015.11.004 · 2015 · External reference
Molecular characterization of the immediate wound response of the solitary ascidian Polycarpa mytiligera
10.1002/dvdy.526 · 2022 · External reference
PPARβ/δ: linking metabolism to regeneration
10.3390/ijms19072013 · 2018 · External reference
Metabolic orchestration of the wound healing response
10.1016/j.cmet.2021.07.017 · 2021 · External reference
Metabolism in physiological cell proliferation and differentiation
10.1016/j.tcb.2013.05.004 · 2013 · External reference
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
10.1038/nature04703 · 2006 · External reference
Macrophage phenotypes regulate scar formation and chronic wound healing
10.3390/ijms18071545 · 2017 · External reference
JAK/STAT signaling in stem cells and regeneration: from Drosophila to vertebrates
10.1242/dev.167643 · 2019 · External reference
Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut
10.1016/j.cell.2009.05.014 · 2009 · External reference
Regulation of stem cell properties of müller glia by JAK/STAT and MAPK signaling in the mammalian retina
10.1155/2017/1610691 · 2017 · External reference
A genetic and developmental pathway from STAT3 to the OCT4-NANOG circuit is essential for maintenance of ICM lineages in vivo
10.1101/gad.221176.113 · 2013 · External reference
Jak1 Integrates cytokine sensing to regulate hematopoietic stem cell function and stress hematopoiesis
10.1016/j.stem.2017.08.011 · 2017 · External reference
Jak/Stat signaling stimulates zebrafish optic nerve regeneration and overcomes the inhibitory actions of Socs3 and Sfpq
10.1523/jneurosci.3898-13.2014 · 2014 · External reference
The stat3/socs3a pathway is a key regulator of hair cell regeneration in zebrafish [corrected]
10.1523/jneurosci.5785-10.2012 · 2012 · External reference
Translational profiling of cardiomyocytes identifies an early Jak1/Stat3 injury response required for zebrafish heart regeneration
10.1073/pnas.1309810110 · 2013 · External reference
TNFα activates MAPK and Jak-Stat pathways to promote mouse Müller cell proliferation
10.1016/j.exer.2020.108353 · 2021 · External reference
Interleukin-6 induces proliferation in adult spinal cord-derived neural progenitors via the JAK2/STAT3 pathway with EGF-induced MAPK phosphorylation
10.1111/j.1365-2184.2008.00537.x · 2008 · External reference
MAPK/ERK pathway as a central regulator in vertebrate organ regeneration
10.3390/ijms23031464 · 2022 · External reference
Isolation of sea squirt (Ciona) gametes, fertilization, dechorionation, and development
10.1101/pdb.prot5344 · 2009 · External reference
A manually curated gene model set for an ascidian, Ciona robusta (Ciona intestinalis Type A)
10.2108/zs210102 · 2022 · External reference
Single-cell transcriptional diversity is a hallmark of developmental potential
10.1126/science.aax0249 · 2020 · External reference
Accurate estimation of cell composition in bulk expression through robust integration of single-cell information
10.1038/s41467-020-15816-6 · 2020 · External reference
Unresolved reference
2025 · External reference
A nearly complete genome of Ciona intestinalis Type A (C. robusta) reveals the contribution of inversion to chromosomal evolution in the genus Ciona
10.1093/gbe/evz228 · 2019 · External reference
Unresolved reference
2013 · External reference
Unresolved reference
2022 · External reference
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
10.1186/s13059-014-0550-8 · 2014 · External reference
clusterProfiler: an R package for comparing biological themes among gene clusters
10.1089/omi.2011.0118 · 2012 · External reference
Unresolved reference
2025 · External reference
Third-generation in situ hybridization chain reaction: multiplexed, quantitative, sensitive, versatile, robust
2018 · External reference
Segment number threshold determines juvenile onset of germline cluster expansion in Platynereis dumerilii
10.1002/jez.b.23100 · 2022 · External reference
NIH Image to ImageJ: 25 years of image analysis
10.1038/nmeth.2089 · 2012 · External reference
Signaling pathways in phagocytosis
10.1002/(sici)1521-1878(199905)21:5<422::aid-bies9>3.0.co;2-# · ExternalCitation · doi-reference
Sox6, jack of all trades: a versatile regulatory protein in vertebrate development
10.1002/dvdy.22639 · ExternalCitation · doi-reference
Molecular characterization of the immediate wound response of the solitary ascidian Polycarpa mytiligera
10.1002/dvdy.526 · ExternalCitation · doi-reference
Closing the wounds: one hundred and twenty five years of regenerative biology in the ascidian Ciona intestinalis
10.1002/dvg.22799 · ExternalCitation · doi-reference
CNBP: a multifunctional nucleic acid chaperone involved in cell death and proliferation control
10.1002/iub.379 · ExternalCitation · doi-reference
Segment number threshold determines juvenile onset of germline cluster expansion in Platynereis dumerilii
10.1002/jez.b.23100 · ExternalCitation · doi-reference
Distal regeneration involves the age dependent activity of branchial sac stem cells in the ascidian Ciona intestinalis
10.1002/reg2.26 · ExternalCitation · doi-reference
Wound-induced cell proliferation during animal regeneration
10.1002/wdev.321 · ExternalCitation · doi-reference
Stem cell systems and regeneration in planaria
10.1007/s00427-012-0426-4 · ExternalCitation · doi-reference
KNTC1 knockdown suppresses cell proliferation of colon cancer
10.1007/s13205-021-02800-0 · ExternalCitation · doi-reference
The cellular and signaling dynamics of salamander limb regeneration
10.1016/j.ceb.2021.07.010 · ExternalCitation · doi-reference
Stem cells are units of natural selection in a colonial ascidian
10.1016/j.cell.2005.10.026 · ExternalCitation · doi-reference
Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut
10.1016/j.cell.2009.05.014 · ExternalCitation · doi-reference
The CASTOR proteins are arginine sensors for the mTORC1 pathway
10.1016/j.cell.2016.02.035 · ExternalCitation · doi-reference
The lipid-modifying enzyme SMPDL3B negatively regulates innate immunity
10.1016/j.celrep.2015.05.006 · ExternalCitation · doi-reference
Sexual and asexual development: two distinct programs producing the same tunicate
10.1016/j.celrep.2020.108681 · ExternalCitation · doi-reference
The DEAD-box helicase DDX56 is a conserved stemness regulator in normal and cancer stem cells
10.1016/j.celrep.2021.108903 · ExternalCitation · doi-reference
RNA exosome ribonuclease DIS3 degrades Pou6f1 to promote mouse pre-implantation cell differentiation
10.1016/j.celrep.2023.112047 · ExternalCitation · doi-reference
Senescence-induced cellular reprogramming drives cnidarian whole-body regeneration
10.1016/j.celrep.2023.112687 · ExternalCitation · doi-reference
Candidate stem cell isolation and transplantation in Hexacorallia
10.1016/j.celrep.2024.114944 · ExternalCitation · doi-reference
Metabolic orchestration of the wound healing response
10.1016/j.cmet.2021.07.017 · ExternalCitation · doi-reference
BMP signaling in axon regeneration
10.1016/j.conb.2014.03.009 · ExternalCitation · doi-reference
The cellular basis for animal regeneration
10.1016/j.devcel.2011.06.016 · ExternalCitation · doi-reference
A generic and cell-type-specific wound response precedes regeneration in planarians
10.1016/j.devcel.2015.11.004 · ExternalCitation · doi-reference
myc maintains embryonic stem cell pluripotency and self-renewal
10.1016/j.diff.2010.05.001 · ExternalCitation · doi-reference
TNFα activates MAPK and Jak-Stat pathways to promote mouse Müller cell proliferation
10.1016/j.exer.2020.108353 · ExternalCitation · doi-reference
The role of Hox genes during vertebrate limb development
10.1016/j.gde.2007.05.011 · ExternalCitation · doi-reference
The interstitial stem cells in Hydractinia and their role in regeneration
10.1016/j.gde.2016.06.006 · ExternalCitation · doi-reference
Macrophages in skin injury and repair
10.1016/j.imbio.2011.01.001 · ExternalCitation · doi-reference
Macrophages in tissue repair, regeneration, and fibrosis
10.1016/j.immuni.2016.02.015 · ExternalCitation · doi-reference
DDX56 promotes EMT and cancer stemness via MELK-FOXM1 axis in hepatocellular carcinoma
10.1016/j.isci.2024.109827 · ExternalCitation · doi-reference
Matrix remodeling by MMPs during wound repair
10.1016/j.matbio.2015.03.002 · ExternalCitation · doi-reference
Identification of IRF-8 and IRF-1 target genes in activated macrophages
10.1016/j.molimm.2006.02.026 · ExternalCitation · doi-reference
IAPs, regulators of innate immunity and inflammation
10.1016/j.semcdb.2014.03.035 · ExternalCitation · doi-reference
Jak1 Integrates cytokine sensing to regulate hematopoietic stem cell function and stress hematopoiesis
10.1016/j.stem.2017.08.011 · ExternalCitation · doi-reference
Hallmarks of regeneration
10.1016/j.stem.2024.07.007 · ExternalCitation · doi-reference
Mechanisms, hallmarks, and implications of stem cell quiescence
10.1016/j.stemcr.2019.05.012 · ExternalCitation · doi-reference
Metabolism in physiological cell proliferation and differentiation
10.1016/j.tcb.2013.05.004 · ExternalCitation · doi-reference
JAK/STAT signaling coordinates stem cell proliferation and multilineage differentiation in the Drosophila intestinal stem cell lineage
10.1016/j.ydbio.2009.10.045 · ExternalCitation · doi-reference
Planarian regeneration involves distinct stem cell responses to wounds and tissue absence
10.1016/j.ydbio.2010.06.017 · ExternalCitation · doi-reference
Phagocyte dynamics in a highly regenerative urochordate: insights into development and host defense
10.1016/j.ydbio.2012.11.006 · ExternalCitation · doi-reference
Evolution of the chordate regeneration blastema: Differential gene expression and conserved role of notch signaling during siphon regeneration in the ascidian Ciona
10.1016/j.ydbio.2015.07.017 · ExternalCitation · doi-reference
Systemic cell cycle activation is induced following complex tissue injury in axolotl
10.1016/j.ydbio.2017.07.010 · ExternalCitation · doi-reference
The blastema and epimorphic regeneration in mammals
10.1016/j.ydbio.2017.08.007 · ExternalCitation · doi-reference
EvoRegen in animals: Time to uncover deep conservation or convergence of adult stem cell evolution and regenerative processes
10.1016/j.ydbio.2017.10.010 · ExternalCitation · doi-reference
Progenitor targeting by adult stem cells in Ciona homeostasis, injury, and regeneration
10.1016/j.ydbio.2018.09.005 · ExternalCitation · doi-reference
Cellular and molecular mechanisms of regeneration in colonial and solitary Ascidians
10.1016/j.ydbio.2018.11.021 · ExternalCitation · doi-reference
Insights into regeneration tool box: An animal model approach
10.1016/j.ydbio.2019.04.006 · ExternalCitation · doi-reference
Stem cells: units of development, units of regeneration, and units in evolution
10.1016/s0092-8674(00)81692-x · ExternalCitation · doi-reference
The ascidian as a model organism in developmental and evolutionary biology
10.1016/s0092-8674(01)00481-0 · ExternalCitation · doi-reference
Heat-shock protein protection
10.1016/s0166-2236(98)01392-7 · ExternalCitation · doi-reference
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
10.1038/nature04703 · ExternalCitation · doi-reference
Reactivating head regrowth in a regeneration-deficient planarian species
10.1038/nature12414 · ExternalCitation · doi-reference
Reparative inflammation takes charge of tissue regeneration
10.1038/nature17039 · ExternalCitation · doi-reference
Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription
10.1038/ncomms11624 · ExternalCitation · doi-reference
NIH Image to ImageJ: 25 years of image analysis
10.1038/nmeth.2089 · ExternalCitation · doi-reference
BMP signalling in skeletal development, disease and repair
10.1038/nrendo.2016.12 · ExternalCitation · doi-reference
Advances in understanding tissue regenerative capacity and mechanisms in animals
10.1038/nrg2879 · ExternalCitation · doi-reference
The JAK/STAT signaling pathway: from bench to clinic
10.1038/s41392-021-00791-1 · ExternalCitation · doi-reference
Alpl prevents bone ageing sensitivity by specifically regulating senescence and differentiation in mesenchymal stem cells
10.1038/s41413-018-0029-4 · ExternalCitation · doi-reference
Accurate estimation of cell composition in bulk expression through robust integration of single-cell information
10.1038/s41467-020-15816-6 · ExternalCitation · doi-reference
Metabolic regulation of cell growth and proliferation
10.1038/s41580-019-0123-5 · ExternalCitation · doi-reference
Regulation of adult stem cell quiescence and its functions in the maintenance of tissue integrity
10.1038/s41580-022-00568-6 · ExternalCitation · doi-reference
Complex mammalian-like haematopoietic system found in a colonial chordate
10.1038/s41586-018-0783-x · ExternalCitation · doi-reference
Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention
10.1038/sj.leu.2402945 · ExternalCitation · doi-reference
Translational profiling of cardiomyocytes identifies an early Jak1/Stat3 injury response required for zebrafish heart regeneration
10.1073/pnas.1309810110 · ExternalCitation · doi-reference
Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activity
10.1073/pnas.96.16.9118 · ExternalCitation · doi-reference
Characterization of the deubiquitinating activity of USP19 and its role in endoplasmic reticulum-associated degradation
10.1074/jbc.m113.538934 · ExternalCitation · doi-reference
Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development
10.1083/jcb.200610046 · ExternalCitation · doi-reference
TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
10.1084/jem.20081297 · ExternalCitation · doi-reference
clusterProfiler: an R package for comparing biological themes among gene clusters
10.1089/omi.2011.0118 · ExternalCitation · doi-reference
A nearly complete genome of Ciona intestinalis Type A (C. robusta) reveals the contribution of inversion to chromosomal evolution in the genus Ciona
10.1093/gbe/evz228 · ExternalCitation · doi-reference
Acute stress is detrimental to heart regeneration in zebrafish
10.1098/rsob.160012 · ExternalCitation · doi-reference
A genetic and developmental pathway from STAT3 to the OCT4-NANOG circuit is essential for maintenance of ICM lineages in vivo
10.1101/gad.221176.113 · ExternalCitation · doi-reference
Isolation of sea squirt (Ciona) gametes, fertilization, dechorionation, and development
10.1101/pdb.prot5344 · ExternalCitation · doi-reference
Interleukin-6 induces proliferation in adult spinal cord-derived neural progenitors via the JAK2/STAT3 pathway with EGF-induced MAPK phosphorylation
10.1111/j.1365-2184.2008.00537.x · ExternalCitation · doi-reference
To regenerate or not to regenerate: Vertebrate model organisms of regeneration-competency and -incompetency
10.1111/wrr.13000 · ExternalCitation · doi-reference
Single-cell transcriptional diversity is a hallmark of developmental potential
10.1126/science.aax0249 · ExternalCitation · doi-reference
Alkaline phosphatase in stem cells
10.1155/2015/628368 · ExternalCitation · doi-reference
Regulation of stem cell properties of müller glia by JAK/STAT and MAPK signaling in the mammalian retina
10.1155/2017/1610691 · ExternalCitation · doi-reference
PAK1 silencing attenuated proinflammatory macrophage activation and foam cell formation by increasing PPARγ expression
10.1155/2021/6957900 · ExternalCitation · doi-reference
Gli1 regulates the proliferation and differentiation of HSCs and myeloid progenitors
10.1182/blood-2009-09-241703 · ExternalCitation · doi-reference
The tetraspanin CD53 protects stressed hematopoietic stem cells via promotion of DREAM complex-mediated quiescence
10.1182/blood.2022016929 · ExternalCitation · doi-reference
Characterization of murine CD34, a marker for hematopoietic progenitor and stem cells
10.1182/blood.v84.3.691.691 · ExternalCitation · doi-reference
Assessment of aldehyde dehydrogenase in viable cells
10.1182/blood.v85.10.2742.bloodjournal85102742 · ExternalCitation · doi-reference
Differentially expressed chaperone genes reveal a stress response required for unidirectional regeneration in the basal chordate Ciona
10.1186/s12915-023-01633-y · ExternalCitation · doi-reference
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
10.1186/s13059-014-0550-8 · ExternalCitation · doi-reference
Ddx56 maintains proliferation of mouse embryonic stem cells via ribosome assembly and interaction with the Oct4/Sox2 complex
10.1186/s13287-020-01800-w · ExternalCitation · doi-reference
Differentiated skeletal cells contribute to blastema formation during zebrafish fin regeneration
10.1242/dev.064717 · ExternalCitation · doi-reference
JAK/STAT signaling in stem cells and regeneration: from Drosophila to vertebrates
10.1242/dev.167643 · ExternalCitation · doi-reference
The JAK/STAT signaling pathway
10.1242/jcs.00963 · ExternalCitation · doi-reference
mTOR signaling at a glance
10.1242/jcs.051011 · ExternalCitation · doi-reference
Neural signaling contributes to heart formation and growth in the invertebrate chordate, Ciona robusta
10.1371/journal.pbio.3003715 · ExternalCitation · doi-reference
Macrophage nuclear receptors: Emerging key players in infectious diseases
10.1371/journal.ppat.1007585 · ExternalCitation · doi-reference
Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis
10.1523/jneurosci.3095-08.2009 · ExternalCitation · doi-reference
Jak/Stat signaling stimulates zebrafish optic nerve regeneration and overcomes the inhibitory actions of Socs3 and Sfpq
10.1523/jneurosci.3898-13.2014 · ExternalCitation · doi-reference
The stat3/socs3a pathway is a key regulator of hair cell regeneration in zebrafish [corrected]
10.1523/jneurosci.5785-10.2012 · ExternalCitation · doi-reference
Role of gelatinases MMP-2 and MMP-9 in tissue remodeling following acute lung injury
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