References

Selective neuronal vulnerability in Parkinson disease

10.1038/nrn.2016.178 · 2017 · External reference

Selective vulnerability in neurodegenerative diseases

10.1038/s41593-018-0221-2 · 2018 · External reference

The vulnerable ventral tegmental area in Parkinson’s disease

10.1016/j.baga.2015.06.001 · 2015 · External reference

Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer’s disease

10.1523/jneurosci.16-14-04491.1996 · 1996 · External reference

Motor neuron vulnerability and resistance in amyotrophic lateral sclerosis

10.1007/s00401-017-1708-8 · 2017 · External reference

A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice

10.1038/nn.2297 · 2009 · External reference

Selective neuronal vulnerability in neurodegenerative diseases: from stressor thresholds to degeneration

10.1016/j.neuron.2011.06.031 · 2011 · External reference

Maintenance of postmitotic neuronal cell identity

10.1038/nn.3731 · 2014 · External reference

A map of terminal regulators of neuronal identity in Caenorhabditis elegans

10.1002/wdev.233 · 2016 · External reference

Neuronal identity control by terminal selectors in worms, flies, and chordates

10.1016/j.conb.2018.12.006 · 2019 · External reference

A terminal selector prevents a Hox transcriptional switch to safeguard motor neuron identity throughout life

10.7554/elife.50065 · 2020 · External reference

Pet-1 is required across different stages of life to regulate serotonergic function

10.1038/nn.2623 · 2010 · External reference

Lmx1b is required for maintenance of central serotonergic neurons and mice lacking central serotonergic system exhibit normal locomotor activity

10.1523/jneurosci.4143-06.2006 · 2006 · External reference

Transcriptional repression by FEZF2 restricts alternative identities of cortical projection neurons

10.1016/j.celrep.2021.109269 · 2021 · External reference

Establishment and maintenance of motor neuron identity via temporal modularity in terminal selector function

2020 · External reference

Transgenic reporter analysis of ChIP-Seq-defined enhancers identifies novel target genes for the terminal selector UNC-3/Collier/Ebf

2021 · External reference

PRC2-mediated repression is essential to maintain identity and function of differentiated dopaminergic and serotonergic neurons

10.1126/sciadv.abo1543 · 2022 · External reference

Polycomb repressive complex 2 (PRC2) silences genes responsible for neurodegeneration

10.1038/nn.4360 · 2016 · External reference

An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype

10.1093/emboj/21.7.1505 · 2002 · External reference

Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity

10.1101/gad.1727208 · 2008 · External reference

DMRT1 prevents female reprogramming in the postnatal mammalian testis

10.1038/nature10239 · 2011 · External reference

Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons

10.1523/jneurosci.3910-09.2009 · 2009 · External reference

Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons

10.1073/pnas.1221077110 · 2013 · External reference

α-Synuclein-induced down-regulation of Nurr1 disrupts GDNF signaling in nigral dopamine neurons

10.1126/scitranslmed.3004676 · 2012 · External reference

An optimized Nurr1 agonist provides disease-modifying effects in Parkinson’s disease models

10.1038/s41467-023-39970-9 · 2023 · External reference

Combined Nurr1 and Foxa2 roles in the therapy of Parkinson’s disease

10.15252/emmm.201506162 · 2016 · External reference

NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection

10.1073/pnas.1007088107 · 2010 · External reference

Pitx3 potentiates Nurr1 in dopamine neuron terminal differentiation through release of SMRT-mediated repression

10.1242/dev.029769 · 2009 · External reference

Pitx3 is required for development of substantia nigra dopaminergic neurons

10.1073/pnas.0230529100 · 2003 · External reference

Pitx3 is required for motor activity and for survival of a subset of midbrain dopaminergic neurons

10.1242/dev.00464 · 2003 · External reference

The essential role of transcription factor Pitx3 in preventing mesodiencephalic dopaminergic neurodegeneration and maintaining neuronal subtype identities during aging

10.1038/s41419-021-04319-x · 2021 · External reference

Transcriptomic atlas of midbrain dopamine neurons uncovers differential vulnerability in a Parkinsonism lesion model

10.7554/elife.89482 · 2024 · External reference

Single-cell epigenome analysis reveals age-associated decay of heterochromatin domains in excitatory neurons in the mouse brain

10.1038/s41422-022-00719-6 · 2022 · External reference

Single-cell and spatial transcriptomics: deciphering brain complexity in health and disease

10.1038/s41582-023-00809-y · 2023 · External reference

Microglia function in the central nervous system during health and neurodegeneration

10.1146/annurev-immunol-051116-052358 · 2017 · External reference

Disease-associated microglia: a universal immune sensor of neurodegeneration

10.1016/j.cell.2018.05.003 · 2018 · External reference

Hallmarks of aging: an expanding universe

10.1016/j.cell.2022.11.001 · 2023 · External reference

Hallmarks of neurodegenerative diseases

10.1016/j.cell.2022.12.032 · 2023 · External reference

Single-cell transcriptomic analysis of Alzheimer’s disease

10.1038/s41586-019-1195-2 · 2019 · External reference

Molecular characterization of selectively vulnerable neurons in Alzheimer’s disease

10.1038/s41593-020-00764-7 · 2021 · External reference

Single-cell atlas reveals correlates of high cognitive function, dementia, and resilience to Alzheimer’s disease pathology

10.1016/j.cell.2023.08.039 · 2023 · External reference

Embryonic motor neuron programming factors reactivate immature gene expression and suppress ALS pathologies in postnatal motor neurons

10.1038/s41593-025-02033-x · 2025 · External reference