Research graph
References from Predicting organoid morphology through a phase field model: Insights into cell division and lumenal pressure. Local targets link to admitted publications; unresolved targets remain external evidence.
Homeostatic mini-intestines through scaffold-guided organoid morphogenesis
10.1038/s41586-020-2724-8 · 2020 · External reference
Engineering organoids
10.1038/s41578-021-00279-y · 2021 · External reference
Generation of multicellular tumor spheroids with microwell-based agarose scaffolds for drug testing
10.1371/journal.pone.0130348 · 2015 · External reference
Suspension culture of separated follicles consisting of differentiated thyroid epithelial cells
10.1073/pnas.77.1.472 · 1980 · External reference
Plural cells organize thyroid follicles through aggregation and linkage in collagen gel culture of porcine follicle cells
10.1210/endo.133.2.8344225 · 1993 · External reference
Generation of functional thyroid from embryonic stem cells
10.1038/nature11525 · 2012 · External reference
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
10.1038/nature07935 · 2009 · External reference
Cell fate coordinates mechano-osmotic forces in intestinal crypt formation
10.1038/s41556-021-00700-2 · 2021 · External reference
Mechanical compartmentalization of the intestinal organoid enables crypt folding and collective cell migration
10.1038/s41556-021-00699-6 · 2021 · External reference
Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro
10.1016/j.stem.2009.11.013 · 2010 · External reference
Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium
10.1016/j.cell.2013.09.008 · 2013 · External reference
In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration
10.1038/nature11826 · 2013 · External reference
Long-term expansion and differentiation of adult murine epidermal stem cells in 3D organoid cultures
10.1073/pnas.1715272116 · 2019 · External reference
Artificial three-dimensional niches deconstruct pancreas development in vitro
10.1242/dev.096628 · 2013 · External reference
Pancreas morphogenesis: branching in and then out
10.1016/bs.ctdb.2020.10.006 · 2021 · External reference
Angiogenesis in vitro
10.1038/288551a0 · 1980 · External reference
Plumbing our organs: lessons from vascular development to instruct lab generated tissues
10.1016/bs.ctdb.2022.02.013 · 2022 · External reference
Lung stem cell differentiation in mice directed by endothelial cells via a BMP4-NFATc1-thrombospondin-1 axis
10.1016/j.cell.2013.12.039 · 2014 · External reference
Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids
10.7554/elife.26575 · 2017 · External reference
Branching morphogenesis
10.1242/dev.184499 · 2020 · External reference
Expansion of adult human pancreatic tissue yields organoids harboring progenitor cells with endocrine differentiation potential
10.1016/j.stemcr.2018.02.005 · 2018 · External reference
Deconstructing the principles of ductal network formation in the pancreas
2018 · External reference
Trafficking of Crumbs3 during cytokinesis is crucial for lumen formation
10.1091/mbc.e09-02-0137 · 2009 · External reference
A molecular network for de novo generation of the apical surface and lumen
10.1038/ncb2106 · 2010 · External reference
Cells into tubes: molecular and physical principles underlying lumen formation in tubular organs
10.1016/bs.ctdb.2020.09.002 · 2021 · External reference
Three-dimensional spatiotemporal modeling of colon cancer organoids reveals that multimodal control of stem cell self-renewal is a critical determinant of size and shape in early stages of tumor growth
10.1007/s11538-017-0294-1 · 2018 · External reference
JNK is antagonized to ensure the correct number of interommatidial cells pattern the Drosophila retina
10.1016/j.ydbio.2017.11.002 · 2018 · External reference
Wnt-YAP interactions in the neural fate of human pluripotent stem cells and the implications for neural organoid formation
10.1080/15476278.2016.1140290 · 2016 · External reference
Designer matrices for intestinal stem cell and organoid culture
10.1038/nature20168 · 2016 · External reference
Mechano-modulatory synthetic niches for liver organoid derivation
10.1038/s41467-020-17161-0 · 2020 · External reference
A simple three-dimensional gut model constructed in a restricted ductal microspace induces intestinal epithelial cell integrity and facilitates absorption assays
10.1039/d0bm00763c · 2020 · External reference
Integration of luminal pressure and signalling in tissue self-organization
2020 · External reference
The mechanics of crypt morphogenesis
10.1038/s41556-021-00703-z · 2021 · External reference
Physics of lumen growth
10.1073/pnas.1722154115 · 2018 · External reference
Genetic control of single lumen formation in the zebrafish gut
10.1038/ncb1621 · 2007 · External reference
Fluid pumping and active flexoelectricity can promote lumen nucleation in cell assemblies
10.1073/pnas.1908481116 · 2019 · External reference
Tissue hydraulics: physics of lumen formation and interaction
10.1016/j.cdev.2021.203724 · 2021 · External reference
Active superelasticity in three-dimensional epithelia of controlled shape
10.1038/s41586-018-0671-4 · 2018 · External reference
Study on multicellular systems using a phase field model
10.1371/journal.pone.0033501 · 2012 · External reference
Numerical study on spindle positioning using phase field method
10.1088/1478-3975/aaee45 · 2018 · External reference
Computational approaches for simulating luminogenesis
10.1016/j.semcdb.2022.05.021 · 2022 · External reference
Computer simulation of emerging asymmetry in the mouse blastocyst
10.1242/dev.014555 · 2008 · External reference
Three-dimensional vertex model for simulating multicellular morphogenesis
10.2142/biophysico.12.0_13 · 2015 · External reference
Collective cell mechanics of epithelial shells with organoid-like morphologies
10.1038/s41467-020-17535-4 · 2020 · External reference
Modelling of epithelial growth, fission and lumen formation during embryonic thyroid development: a combination of computational and experimental approaches
10.3389/fendo.2021.655862 · 2021 · External reference
Computational investigation of epithelial cell dynamic phenotype in vitro
10.1186/1742-4682-6-8 · 2009 · External reference
A computational approach to resolve cell level contributions to early glandular epithelial cancer progression
10.1186/1752-0509-3-122 · 2009 · External reference
MDCK cystogenesis driven by cell stabilization within computational analogues
10.1371/journal.pcbi.1002030 · 2011 · External reference
Apoptosis: Opening PANdora’s BoX
10.1016/j.cub.2010.12.018 · 2011 · External reference
Polarity, cell division, and out-of-equilibrium dynamics control the growth of epithelial structures
10.1083/jcb.201305044 · 2013 · External reference
A liver-centric multiscale modeling framework for xenobiotics
10.1371/journal.pone.0162428 · 2016 · External reference
Dear microtubule, I see you
10.1091/mbc.e16-06-0372 · 2016 · External reference
A stochastic reaction scheme for drug/metabolite interaction
10.1016/j.jtbi.2009.03.031 · 2009 · External reference
Cellular Potts modeling of complex multicellular behaviors in tissue morphogenesis
10.1111/dgd.12358 · 2017 · External reference
Bursts and cavity formation in Hydra cells aggregates: experiments and simulations
10.1016/s0378-4371(01)00199-6 · 2001 · External reference
Mechanocellular models of epithelial morphogenesis
10.1098/rstb.2015.0519 · 2017 · External reference
A computational study of the development of epithelial acini: I. Sufficient conditions for the formation of a hollow structure
10.1007/s11538-007-9274-1 · 2008 · External reference
A computational study of the development of epithelial acini: II. Necessary conditions for structure and lumen stability
10.1007/s11538-008-9308-3 · 2008 · External reference
Computational models of VEGF-associated angiogenic processes in cancer
10.1093/imammb/dqq025 · 2012 · External reference
Homeostatic imbalance in epithelial ducts and its role in carcinogenesis
2012 · External reference
Computational modelling unveils how epiblast remodelling and positioning rely on trophectoderm morphogenesis during mouse implantation
10.1371/journal.pone.0254763 · 2021 · External reference
Quantitative modeling identifies critical cell mechanics driving bile duct lumen formation
10.1371/journal.pcbi.1009653 · 2022 · External reference
Interacting active surfaces: a model for three-dimensional cell aggregates
10.1371/journal.pcbi.1010762 · 2022 · External reference
Modelling contractile ring formation and division to daughter cells for simulating proliferative multicellular dynamics
10.1140/epje/s10189-023-00315-5 · 2023 · External reference
A 3D multi-agent-based model for lumen morphogenesis: the role of the biophysical properties of the extracellular matrix
10.1007/s00366-022-01654-1 · 2022 · External reference
An agent-based modelling framework to study growth mechanisms in EGFR-L858R mutant cell alveolar type II cells
10.1098/rsos.240413 · 2024 · External reference
Paneth cell-rich regions separated by a cluster of Lgr5+ cells initiate crypt fission in the intestinal stem cell niche
10.1371/journal.pbio.1002491 · 2016 · External reference
Generic rules of lumen nucleation and fusion in epithelial organoids
2024 · External reference
Myosin heads contribute to the maintenance of filament order in relaxed rabbit muscle
10.1016/j.bpj.2010.06.072 · 2010 · External reference
On the biomechanics of stem cell niche formation in the gut–modelling growing organoids
10.1111/j.1742-4658.2012.08646.x · 2012 · External reference
Volume growth in animal cells is cell cycle dependent and shows additive fluctuations
10.7554/elife.70816 · 2022 · External reference
Mechanical feedback as a possible regulator of tissue growth
10.1073/pnas.0404782102 · 2005 · External reference
A model for cyst lumen expansion and size regulation via fluid secretion
10.1016/j.jtbi.2010.03.021 · 2010 · External reference
Hydraulic control of mammalian embryo size and cell fate
10.1038/s41586-019-1309-x · 2019 · External reference
An in vitro test of the cell stretch-proliferation hypothesis of renal cyst enlargement
10.1681/asn.v641230 · 1995 · External reference
Instabilities of monolayered epithelia: shape and structure of villi and crypts
10.1103/physrevlett.107.078104 · 2011 · External reference
10.1101/2023.05.23.541893
10.1101/2023.05.23.541893 · External reference
Control of lumen geometry and topology by the interplay between pressure and cell proliferation rate in pancreatic organoids
2024 · External reference
Unresolved reference
External reference
10.1016/j.gde.2021.10.001
10.1016/j.gde.2021.10.001 · External reference
Spatiotemporal dynamics of self-organized branching in pancreas-derived organoids
10.1038/s41467-022-32806-y · 2022 · External reference
The physics of cell-size regulation across timescales
10.1038/s41567-019-0629-y · 2019 · External reference
Mechanical convergence in mixed populations of mammalian epithelial cells
10.1140/epje/s10189-024-00415-w · 2024 · External reference
10.1093/acprof:oso/9780199652952.001.0001
10.1093/acprof:oso/9780199652952.001.0001 · External reference
Cell-ECM traction force modulates endogenous tension at cell-cell contacts
10.1073/pnas.1011123108 · 2011 · External reference
Vinculin phosphorylation at residues Y100 and Y1065 is required for cellular force transmission
2015 · External reference
