Research graph
References from Optimal control of multiple myeloma assuming drug resistance and off-target effects. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
External reference
Multiple myeloma
10.1016/s0140-6736(09)60221-x · 2009 · External reference
Treatment strategy for multiple myeloma to improve immunological environment and maintain MRD negativity
10.3390/cancers13194867 · 2021 · External reference
Healthcare costs of multiple myeloma patients with four or more prior lines of therapy, including triple-class exposure in the United States
10.1007/s40487-022-00198-0 · 2022 · External reference
Daratumumab for the treatment of multiple Myeloma
10.3389/fimmu.2018.01228 · 2018 · External reference
Daratumumab depletes CD38+ immune regulatory cells, promotes T-cell expansion, and skews T-cell repertoire in multiple myeloma
10.1182/blood-2015-12-687749 · 2016 · External reference
Anti-CS1 humanized monoclonal antibody HuLuc63 inhibits myeloma cell adhesion and induces antibody-dependent cellular cytotoxicity in the bone marrow milieu
10.1182/blood-2007-08-107292 · 2008 · External reference
Elotuzumab: first global approval
10.1007/s40265-016-0540-0 · 2016 · External reference
Lenalidomide in the treatment of multiple myeloma: a review
10.1111/j.1365-2710.2008.00920.x · 2008 · External reference
Elotuzumab therapy for relapsed or refractory multiple myeloma
10.1056/nejmoa1505654 · 2015 · External reference
Daratumumab, bortezomib, lenalidomide, and dexamethasone for multiple myeloma
10.1056/nejmoa2312054 · 2024 · External reference
Daratumumab monotherapy for patients with intermediate-risk or high-risk smoldering multiple myeloma: a randomized, open-label, multicenter, phase 2 study (CENTAURUS)
10.1038/s41375-020-0718-z · 2020 · External reference
Mechanisms of resistance to anti-CD38 daratumumab in multiple myeloma
10.3390/cells9010167 · 2020 · External reference
Daratumumab (anti-CD38) induces loss of CD38 on red blood cells
10.1182/blood-2016-11-749432 · 2017 · External reference
Maintenance with daratumumab or observation following treatment with bortezomib, thalidomide, and dexamethasone with or without daratumumab and autologous stem-cell transplant in patients with newly diagnosed multiple myeloma (CASSIOPEIA): an open-label, randomised, phase 3 trial
10.1016/s1470-2045(21)00428-9 · 2021 · External reference
Notice sur la loi que la population poursuit dans son accroissement
1838 · External reference
Recherches mathématiques sur la loi d’accroissement de la population
1845 · External reference
Contribution to the theory of periodic reactions
10.1021/j150111a004 · 1910 · External reference
On the volterra and other nonlinear models of interacting populations
10.1103/revmodphys.43.231 · 1971 · External reference
A review of dynamical systems approaches for the detection of chaotic attractors in cancer networks
10.1016/j.patter.2021.100226 · 2021 · External reference
CAR T cell therapy in B-cell acute lymphoblastic leukaemia: Insights from mathematical models
10.1016/j.cnsns.2020.105570 · 2021 · External reference
A generalised prey-predator type model of immunogenic cancer with the effect of immunotherapy
10.4314/ijest.v5i1.6 · 2018 · External reference
CAR-T cell therapy: current limitations and potential strategies
10.1038/s41408-021-00459-7 · 2021 · External reference
Predator-prey in tumor-immune interactions: a wrong model or just an incomplete one?
10.3389/fimmu.2021.668221 · 2021 · External reference
Tumour immunotherapy: lessons from predator-prey theory
10.1038/s41577-022-00719-y · 2022 · External reference
The mathematical theory of optimal processes
1962 · External reference
Optimal CAR T-cell immunotherapy strategies for a leukemia treatment model
10.3390/g11040053 · 2020 · External reference
Optimal control design for drug delivery of immunotherapy in chemoimmunotherapy treatment
10.1016/j.cmpb.2022.107248 · 2023 · External reference
10.1007/978-3-319-98083-6_5
10.1007/978-3-319-98083-6_5 · External reference
Feedback mechanisms control coexistence in a stem cell model of acute myeloid leukaemia
10.1016/j.jtbi.2016.04.002 · 2016 · External reference
Optimal control of acute myeloid leukaemia
10.1016/j.jtbi.2019.03.006 · 2019 · External reference
On the role of the objective in the optimization of compartmental models for biomedical therapies
10.1007/s10957-020-01754-2 · 2020 · External reference
Bang-bang optimal controls for a mathematical model of chemo- and immunotherapy in cancer
10.3934/dcdsb.2023141 · 2024 · External reference
On the “bang-bang” control problem
10.1090/qam/78516 · 1956 · External reference
The existence of optimal controls in the absence of convexity conditions
10.1016/0022-247x(63)90081-7 · 1963 · External reference
Optimal bang-bang controls for a two-compartment model in cancer chemotherapy
10.1023/a:1016027113579 · 2002 · External reference
Relationship between whole-body tumor burden, clinical phenotype, and quality of life in patients with neurofibromatosis
10.1002/ajmg.a.36466 · 2014 · External reference
Phase 1/2 study of daratumumab, lenalidomide, and dexamethasone for relapsed multiple myeloma
10.1182/blood-2016-07-726729 · 2016 · External reference
Subcutaneous delivery of daratumumab in relapsed or refractory multiple myeloma
10.1182/blood.2019000667 · 2019 · External reference
Best practice for the administration of daratumumab in multiple myeloma: Australian myeloma nurse expert opinion
10.4103/apjon.apjon_9_18 · 2018 · External reference
CD38 expression and complement inhibitors affect response and resistance to daratumumab therapy in myeloma
10.1182/blood-2016-03-703439 · 2016 · External reference
Reinforcement learning informs optimal treatment strategies to limit antibiotic resistance
10.1073/pnas.2303165121 · 2024 · External reference
Mathematical model-driven deep learning enables personalized adaptive therapy
10.1158/0008-5472.can-23-2040 · 2024 · External reference
An indirect approach for singular optimal control problems
10.1016/j.compchemeng.2020.106923 · 2020 · External reference
Method for solving bang-bang and singular optimal control problems using adaptive Radau collocation
10.1007/s10589-022-00350-6 · 2022 · External reference