Research graph
References from Machine learning on multiple epigenetic features reveals H3K27Ac as a driver of gene expression prediction across patients with glioblastoma. Local targets link to admitted publications; unresolved targets remain external evidence.
Cancer stem cells in glioblastoma
10.1101/gad.261982.115 · 2015 · External reference
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
10.1126/science.1254257 · 2014 · External reference
Genome-Wide Histone Modifications and CTCF Enrichment Predict Gene Expression in Sheep Macrophages
10.3389/fgene.2020.612031 · 2021 · External reference
An integrated encyclopedia of DNA elements in the human genome
10.1038/nature11247 · 2012 · External reference
New developments on the Encyclopedia of DNA Elements (ENCODE) data portal
2020 · External reference
Chromatin accessibility: biological functions, molecular mechanisms and therapeutic application
2024 · External reference
RNA polymerase II promotes the organization of chromatin following DNA replication
10.1038/s44319-024-00085-x · 2024 · External reference
RNA polymerase II speed: a key player in controlling and adapting transcriptome composition
10.15252/embj.2020105740 · 2021 · External reference
Release of promoter–proximal paused Pol II in response to histone deacetylase inhibition
10.1093/nar/gkaa234 · 2020 · External reference
Unresolved reference
External reference
Histone H3K27ac separates active from poised enhancers and predicts developmental state
10.1073/pnas.1016071107 · 2010 · External reference
Unresolved reference
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An Integrative Framework for Combining Sequence and Epigenomic Data to Predict Transcription Factor Binding Sites Using Deep Learning
10.1109/tcbb.2019.2901789 · 2021 · External reference
The ENCODE Uniform Analysis Pipelines
2017 · External reference
Unresolved reference
External reference
An integrative ENCODE resource for cancer genomics
10.1038/s41467-020-14743-w · 2020 · External reference
Index and biological spectrum of human DNase I hypersensitive sites
10.1038/s41586-020-2559-3 · 2020 · External reference
Transforming RNA-Seq data to improve the performance of prognostic gene signatures
10.1371/journal.pone.0085150 · 2014 · External reference
10.21203/rs.3.rs-3088639/v1
10.21203/rs.3.rs-3088639/v1 · External reference
Predicting gene expression in the human malaria parasite Plasmodium falciparum using histone modification, nucleosome positioning, and 3D localization features
2019 · External reference
Integrating Long-Range Regulatory Interactions to Predict Gene Expression Using Graph Convolutional Networks
10.1089/cmb.2021.0316 · 2022 · External reference
Chromatin interaction-aware gene regulatory modeling with graph attention networks
2022 · External reference
On the cross-population generalizability of gene expression prediction models
2020 · External reference
Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma
10.1084/jem.20190196 · 2019 · External reference
DeepChrome: deep-learning for predicting gene expression from histone modifications
2016 · External reference
Unresolved reference
2022 · External reference
Navigating the pitfalls of applying machine learning in genomics
10.1038/s41576-021-00434-9 · 2022 · External reference
Promoter-proximal CTCF binding promotes distal enhancer-dependent gene activation
10.1038/s41594-020-00539-5 · 2021 · External reference
Glioblastoma Stem Cells Respond to Differentiation Cues but Fail to Undergo Commitment and Terminal Cell-Cycle Arrest
10.1016/j.stemcr.2015.09.014 · 2015 · External reference
Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment
10.1038/s41467-019-09853-z · 2019 · External reference
Conversion of differentiated cancer cells into cancer stem-like cells in a glioblastoma model after primary chemotherapy
10.1038/cdd.2014.31 · 2014 · External reference
Unresolved reference
2022 · External reference
Systematic discovery and functional dissection of enhancers needed for cancer cell fitness and proliferation
10.1016/j.celrep.2022.111630 · 2022 · External reference
Superenhancers as master gene regulators and novel therapeutic targets in brain tumors
10.1038/s12276-023-00934-0 · 2023 · External reference
Unresolved reference
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Unresolved reference
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Unresolved reference
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Attend and Predict: Understanding Gene Regulation by Selective Attention on Chromatin
2017 · External reference
