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References from OCIAD2 as a novel prognostic and therapeutic biomarker for pancreatic cancer: A study based on transcriptomic signature and bioinformatics analysis. Local targets link to admitted publications; unresolved targets remain external evidence.
Cancer statistics, 2023
2023 · External reference
Burden of Pancreatic Cancer: From Epidemiology to Practice
10.1016/j.cgh.2020.02.054 · 2021 · External reference
Pancreatic cancer: Advances and challenges
10.1016/j.cell.2023.02.014 · 2023 · External reference
Treatment landscape of metastatic pancreatic cancer
10.1016/j.ctrv.2021.102180 · 2021 · External reference
Covalent inhibitor targets KRasG12C: A new paradigm for drugging the undruggable and challenges ahead
10.1016/j.gendis.2021.08.011 · 2021 · External reference
Overall Survival Results From the POLO Trial: A Phase III Study of Active Maintenance Olaparib Versus Placebo for Germline BRCA-Mutated Metastatic Pancreatic Cancer
10.1200/jco.21.01604 · 2022 · External reference
Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer
10.1056/nejmoa1903387 · 2019 · External reference
Phase II study evaluating the association of gemcitabine, trastuzumab and erlotinib as first-line treatment in patients with metastatic pancreatic adenocarcinoma (GATE 1)
10.1002/ijc.33225 · 2021 · External reference
Cetuximab in Pancreatic Cancer Therapy: A Systematic Review and Meta-Analysis
10.1159/000502844 · 2020 · External reference
A Contemporary Review of the Treatment Landscape and the Role of Predictive and Prognostic Biomarkers in Pancreatic Adenocarcinoma
2018 · External reference
Biomarker-based therapy in pancreatic ductal adenocarcinoma: an emerging reality?
10.1158/1078-0432.ccr-16-3169 · 2018 · External reference
A comprehensive review of pancreatic cancer and its therapeutic challenges
10.18632/aging.204310 · 2022 · External reference
Mathematical Modeling to Address Challenges in Pancreatic Cancer
10.2174/1568026620666200101095641 · 2020 · External reference
Perineural Invasion Reprograms the Immune Microenvironment through Cholinergic Signaling in Pancreatic Ductal Adenocarcinoma
10.1158/0008-5472.can-19-2689 · 2020 · External reference
Dysregulation of HNF1B/Clusterin axis enhances disease progression in a highly aggressive subset of pancreatic cancer patients
10.1093/carcin/bgac092 · 2022 · External reference
Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma
10.1038/ng.3398 · 2015 · External reference
A Novel MIF Signaling Pathway Drives the Malignant Character of Pancreatic Cancer by Targeting NR3C2
10.1158/0008-5472.can-15-2841 · 2016 · External reference
DPEP1 inhibits tumor cell invasiveness, enhances chemosensitivity and predicts clinical outcome in pancreatic ductal adenocarcinoma
10.1371/journal.pone.0031507 · 2012 · External reference
Prognostic relevance of molecular subtypes and master regulators in pancreatic ductal adenocarcinoma
10.1186/s12885-016-2540-6 · 2016 · External reference
Molecular signatures of mRNAs and miRNAs as prognostic biomarkers in pancreatobiliary and intestinal types of periampullary adenocarcinomas
10.1016/j.molonc.2014.12.002 · 2015 · External reference
Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt
10.1038/nprot.2009.97 · 2009 · External reference
limma powers differential expression analyses for RNA-sequencing and microarray studies
10.1093/nar/gkv007 · 2015 · External reference
clusterProfiler 4.0: A universal enrichment tool for interpreting omics data
2021 · External reference
Integrated analysis of public datasets for the discovery and validation of survival-associated genes in solid tumors
2024 · External reference
Visualizing and interpreting cancer genomics data via the Xena platform
10.1038/s41587-020-0546-8 · 2020 · External reference
RNA sequencing of pancreatic adenocarcinoma tumors yields novel expression patterns associated with long-term survival and reveals a role for ANGPTL4
10.1016/j.molonc.2016.05.004 · 2016 · External reference
Estimating and comparing time-dependent areas under receiver operating characteristic curves for censored event times with competing risks
10.1002/sim.5958 · 2013 · External reference
Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells
10.1038/s43018-022-00463-1 · 2022 · External reference
Single-cell transcriptome analysis of tumor and stromal compartments of pancreatic ductal adenocarcinoma primary tumors and metastatic lesions
10.1186/s13073-020-00776-9 · 2020 · External reference
Single cell transcriptomic analyses implicate an immunosuppressive tumor microenvironment in pancreatic cancer liver metastasis
10.1038/s41467-023-40727-7 · 2023 · External reference
Immune profiling and prognostic model of pancreatic cancer using quantitative pathology and single-cell RNA sequencing
10.1186/s12967-023-04051-4 · 2023 · External reference
Analysis of Donor Pancreata Defines the Transcriptomic Signature and Microenvironment of Early Neoplastic Lesions
10.1158/2159-8290.cd-23-0013 · 2023 · External reference
Elucidation of Tumor-Stromal Heterogeneity and the Ligand-Receptor Interactome by Single-Cell Transcriptomics in Real-world Pancreatic Cancer Biopsies
10.1158/1078-0432.ccr-20-3925 · 2021 · External reference
Dictionary learning for integrative, multimodal and scalable single-cell analysis
10.1038/s41587-023-01767-y · 2024 · External reference
Fast, sensitive and accurate integration of single-cell data with Harmony
10.1038/s41592-019-0619-0 · 2019 · External reference
dittoSeq: universal user-friendly single-cell and bulk RNA sequencing visualization toolkit
10.1093/bioinformatics/btaa1011 · 2021 · External reference
Proteomics. Tissue-based map of the human proteome
10.1126/science.1260419 · 2015 · External reference
GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses
10.1093/nar/gkx247 · 2017 · External reference
decoupleR: ensemble of computational methods to infer biological activities from omics data
2022 · External reference
Correlating chemical sensitivity and basal gene expression reveals mechanism of action
10.1038/nchembio.1986 · 2016 · External reference
oncoPredict: an R package for predicting in vivo or cancer patient drug response and biomarkers from cell line screening data
10.1093/bib/bbab260 · 2021 · External reference
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences
10.1073/pnas.242603899 · 2002 · External reference
The OCIAD protein family: comparative developmental biology and stem cell application
10.1387/ijdb.190038mi · 2020 · External reference
A novel risk stratification model based on the Children’s Hepatic Tumours International Collaboration-Hepatoblastoma Stratification and deoxyribonucleic acid methylation analysis for hepatoblastoma
10.1016/j.ejca.2022.06.013 · 2022 · External reference
Clinical prognostic value of DNA methylation in hepatoblastoma: Four novel tumor suppressor candidates
10.1111/cas.12928 · 2016 · External reference
OCIAD2 suppressed tumor growth and invasion via AKT pathway in Hepatocelluar carcinoma
10.1093/carcin/bgx073 · 2017 · External reference
Increased expression of OCIA domain containing 2 during stepwise progression of ovarian mucinous tumor
10.1111/j.1440-1827.2012.02825.x · 2012 · External reference
Aberrant OCIAD2 demethylation in lung adenocarcinoma is associated with outcome
10.1111/pin.13262 · 2022 · External reference
Ovarian carcinoma immunoreactive antigen domain 2 controls mitochondrial apoptosis in lung adenocarcinoma
10.1111/cas.15160 · 2021 · External reference
High expression of ovarian cancer immunoreactive antigen domain containing 2 (OCIAD2) is associated with poor prognosis in lung adenocarcinoma
10.1111/pin.12724 · 2018 · External reference
OCIA domain containing 2 is highly expressed in adenocarcinoma mixed subtype with bronchioloalveolar carcinoma component and is associated with better prognosis
10.1111/j.1349-7006.2006.00346.x · 2007 · External reference
OCIAD2 promotes pancreatic cancer progression through the AKT signaling pathway
10.1016/j.gene.2024.148735 · 2024 · External reference