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References from Balanced contractility and adhesion drive polarization in a minimal elastic actomyosin network. Local targets link to admitted publications; unresolved targets remain external evidence.
Cell migration: a physically integrated molecular process
10.1016/s0092-8674(00)81280-5 · 1996 · External reference
Cell motility resulting from spontaneous polymerization waves
10.1103/physrevlett.107.258103 · 2011 · External reference
The mechanisms of spatial and temporal patterning of cell-edge dynamics
10.1016/j.ceb.2015.09.001 · 2015 · External reference
Deterministic actin waves as generators of cell polarization cues
10.1073/pnas.1907845117 · 2020 · External reference
Cytoskeletal crosstalk in cell migration
10.1016/j.tcb.2020.06.004 · 2020 · External reference
Cytoskeletal symmetry breaking in animal cells
10.1016/j.ceb.2021.07.003 · 2021 · External reference
Coordinating cell polarization and morphogenesis through mechanical feedback
10.1371/journal.pcbi.1007971 · 2021 · External reference
The mechanics behind cell polarity
10.1016/j.tcb.2012.08.005 · 2012 · External reference
Origins of cell polarity
10.1016/s0092-8674(00)81278-7 · 1996 · External reference
Acto-myosin based response to stiffness and rigidity sensing
10.4161/cam.5.1.13281 · 2011 · External reference
Self-organization of protrusions and polarity during eukaryotic chemotaxis
10.1016/j.ceb.2014.06.007 · 2014 · External reference
Physical influences of the extracellular environment on cell migration
10.1038/nrm3897 · 2014 · External reference
Electrochemical control of cell and tissue polarity
10.1146/annurev-cellbio-100913-013357 · 2014 · External reference
Electrophoresis of cellular membrane components creates the directional cue guiding keratocyte galvanotaxis
10.1016/j.cub.2013.02.047 · 2013 · External reference
Cell mechanics at the rear act to steer the direction of cell migration
2020 · External reference
Self-polarization and directional motility of cytoplasm
10.1016/s0960-9822(99)80042-6 · 1999 · External reference
Actin-myosin network reorganization breaks symmetry at the cell rear to spontaneously initiate polarized cell motility
10.1083/jcb.200706012 · 2007 · External reference
Forming the cell rear first: breaking cell symmetry to trigger directed cell migration
10.1038/ncb0710-628 · 2010 · External reference
Repellent and attractant guidance cues initiate cell migration by distinct rear-driven and front-driven cytoskeletal mechanisms
10.1016/j.cub.2018.02.024 · 2018 · External reference
From simple to detailed models for cell polarization
10.1098/rstb.2013.0003 · 2013 · External reference
Experiment, theory, and the keratocyte: an ode to a simple model for cell motility
10.1016/j.semcdb.2019.10.019 · 2020 · External reference
Polarization and movement of keratocytes: a multiscale modelling approach
10.1007/s11538-006-9131-7 · 2006 · External reference
Interaction of motility, directional sensing, and polarity modules recreates the behaviors of chemotaxing cells
2013 · External reference
A hybrid stochastic-deterministic mechanochemical model of cell polarization
10.1091/mbc.e19-09-0549 · 2020 · External reference
Mechanisms of cell polarization
10.1016/j.coisb.2017.03.005 · 2017 · External reference
Membrane tension maintains cell polarity by confining signals to the leading edge during neutrophil migration
10.1016/j.cell.2011.10.050 · 2012 · External reference
A minimal cell model for lamellipodia-based cellular dynamics and migration
10.1242/jcs.260744 · 2023 · External reference
Actin flows mediate a universal coupling between cell speed and cell persistence
10.1016/j.cell.2015.01.056 · 2015 · External reference
Effects of adhesion dynamics and substrate compliance on the shape and motility of crawling cells
10.1371/journal.pone.0064511 · 2013 · External reference
Collective Langevin dynamics of flexible cytoskeletal fibers
10.1088/1367-2630/9/11/427 · 2007 · External reference
Computational analysis of viscoelastic properties of crosslinked actin networks
2009 · External reference
Simulations of dynamically cross-linked actin networks: morphology, rheology, and hydrodynamic interactions
10.1371/journal.pcbi.1009240 · 2021 · External reference
Discrete mechanical model of lamellipodial actin network implements molecular clutch mechanism and generates arcs and microspikes
10.1371/journal.pcbi.1009506 · 2021 · External reference
Fiber networks amplify active stress
10.1073/pnas.1514208113 · 2016 · External reference
Balance between cell-substrate adhesion and myosin contraction determines the frequency of motility initiation in fish keratocytes
10.1073/pnas.1417257112 · 2015 · External reference
Stick-slip model for actin-driven cell protrusions, cell polarization, and crawling
10.1073/pnas.2011785117 · 2020 · External reference
Interplay between mechanosensitive adhesions and membrane tension regulates cell motility
10.1103/prxlife.1.023007 · 2023 · External reference
Minimal model for spontaneous cell polarization and edge activity in oscillating, rotating and migrating cells
10.1038/nphys3615 · 2016 · External reference
Traction forces control cell-edge dynamics and mediate distance sensitivity during cell polarization
10.1016/j.cub.2020.02.078 · 2020 · External reference
Modeling semiflexible polymer networks
10.1103/revmodphys.86.995 · 2014 · External reference
Long-range self-organization of cytoskeletal myosin II filament stacks
10.1038/ncb3466 · 2017 · External reference
Flexural rigidity of microtubules and actin filaments measured from thermal fluctuations in shape
10.1083/jcb.120.4.923 · 1993 · External reference
Attachment conditions control actin filament buckling and the production of forces
10.1529/biophysj.106.094672 · 2007 · External reference
Dendritic organization of actin comet tails
10.1016/s0960-9822(01)00022-7 · 2001 · External reference
Tying a molecular knot with optical tweezers
10.1038/20894 · 1999 · External reference
F-actin buckling coordinates contractility and severing in a biomimetic actomyosin cortex
10.1073/pnas.1214753109 · 2012 · External reference
A cytoskeletal demolition worker: myosin II acts as an actin depolymerization agent
10.1016/j.jmb.2007.09.066 · 2008 · External reference
Myosin motors fragment and compact membrane-bound actin filaments
10.7554/elife.00116 · 2013 · External reference
Using point cloud data to identify, trace, and regularize the outlines of buildings
10.1080/01431161.2015.1131868 · 2016 · External reference
Contact angle at the leading edge controls cell protrusion rate
10.1016/j.cub.2014.03.050 · 2014 · External reference
Control of actin dynamics in cell motility
10.1006/jmbi.1997.1062 · 1997 · External reference
Unresolved reference
External reference
Unresolved reference
External reference
Fiji: an open-source platform for biological-image analysis
10.1038/nmeth.2019 · 2012 · External reference
Arp2/3 complex inhibition radically alters lamellipodial actin architecture, suspended cell shape, and the cell spreading process
10.1091/mbc.e14-07-1244 · 2015 · External reference
Integrins modulate T cell receptor signaling by constraining actin flow at the immunological synapse
10.3389/fimmu.2018.00025 · 2018 · External reference
Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed
10.1083/jcb.200810060 · 2008 · External reference
Contraction-driven cell motility
10.1103/physrevlett.111.108102 · 2013 · External reference
Mechanics of motility initiation and motility arrest in crawling cells
10.1016/j.jmps.2015.08.006 · 2015 · External reference
High-resolution cell outline segmentation and tracking from phase-contrast microscopy images
10.1111/j.1365-2818.2011.03558.x · 2012 · External reference
Adhesion-mediated mechanosensitivity: a time to experiment, and a time to theorize
10.1016/j.ceb.2006.08.012 · 2006 · External reference
Stick-slip dynamics of cell adhesion triggers spontaneous symmetry breaking and directional migration of mesenchymal cells on one-dimensional lines
10.1126/sciadv.aau5670 · 2020 · External reference
Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness
10.1038/385537a0 · 1997 · External reference
Spatiotemporal feedback between actomyosin and focal-adhesion systems optimizes rapid cell migration
10.1016/j.cell.2006.05.029 · 2006 · External reference
Synthetic control of actin polymerization and symmetry breaking in active protocells
10.1126/sciadv.adk9731 · 2024 · External reference
Active gel model for one-dimensional cell migration coupling actin flow and adhesion dynamics
10.1088/1367-2630/ad63c5 · 2024 · External reference
Mechanics of biomimetic liposomes encapsulating an actin shell
10.1016/j.bpj.2015.10.050 · 2015 · External reference
Shaping up synthetic cells
10.1088/1478-3975/aab923 · 2018 · External reference
Membrane tension induces F-actin reorganization and flow in a biomimetic model cortex
10.1038/s42003-023-04684-7 · 2023 · External reference
Reconstituting the actin cytoskeleton at or near surfaces in vitro
10.1016/j.bbamcr.2015.07.021 · 2015 · External reference
Control of actin dynamics in cell motility
10.1006/jmbi.1997.1062 · ExternalCitation · doi-reference
Polarization and movement of keratocytes: a multiscale modelling approach
10.1007/s11538-006-9131-7 · ExternalCitation · doi-reference
Reconstituting the actin cytoskeleton at or near surfaces in vitro
10.1016/j.bbamcr.2015.07.021 · ExternalCitation · doi-reference
Mechanics of biomimetic liposomes encapsulating an actin shell
10.1016/j.bpj.2015.10.050 · ExternalCitation · doi-reference
Adhesion-mediated mechanosensitivity: a time to experiment, and a time to theorize
10.1016/j.ceb.2006.08.012 · ExternalCitation · doi-reference
Self-organization of protrusions and polarity during eukaryotic chemotaxis
10.1016/j.ceb.2014.06.007 · ExternalCitation · doi-reference
The mechanisms of spatial and temporal patterning of cell-edge dynamics
10.1016/j.ceb.2015.09.001 · ExternalCitation · doi-reference
Cytoskeletal symmetry breaking in animal cells
10.1016/j.ceb.2021.07.003 · ExternalCitation · doi-reference
Spatiotemporal feedback between actomyosin and focal-adhesion systems optimizes rapid cell migration
10.1016/j.cell.2006.05.029 · ExternalCitation · doi-reference
Membrane tension maintains cell polarity by confining signals to the leading edge during neutrophil migration
10.1016/j.cell.2011.10.050 · ExternalCitation · doi-reference
Actin flows mediate a universal coupling between cell speed and cell persistence
10.1016/j.cell.2015.01.056 · ExternalCitation · doi-reference
Mechanisms of cell polarization
10.1016/j.coisb.2017.03.005 · ExternalCitation · doi-reference
Electrophoresis of cellular membrane components creates the directional cue guiding keratocyte galvanotaxis
10.1016/j.cub.2013.02.047 · ExternalCitation · doi-reference
Contact angle at the leading edge controls cell protrusion rate
10.1016/j.cub.2014.03.050 · ExternalCitation · doi-reference
Repellent and attractant guidance cues initiate cell migration by distinct rear-driven and front-driven cytoskeletal mechanisms
10.1016/j.cub.2018.02.024 · ExternalCitation · doi-reference
Traction forces control cell-edge dynamics and mediate distance sensitivity during cell polarization
10.1016/j.cub.2020.02.078 · ExternalCitation · doi-reference
A cytoskeletal demolition worker: myosin II acts as an actin depolymerization agent
10.1016/j.jmb.2007.09.066 · ExternalCitation · doi-reference
Mechanics of motility initiation and motility arrest in crawling cells
10.1016/j.jmps.2015.08.006 · ExternalCitation · doi-reference
Experiment, theory, and the keratocyte: an ode to a simple model for cell motility
10.1016/j.semcdb.2019.10.019 · ExternalCitation · doi-reference
The mechanics behind cell polarity
10.1016/j.tcb.2012.08.005 · ExternalCitation · doi-reference
Cytoskeletal crosstalk in cell migration
10.1016/j.tcb.2020.06.004 · ExternalCitation · doi-reference
Origins of cell polarity
10.1016/s0092-8674(00)81278-7 · ExternalCitation · doi-reference
Cell migration: a physically integrated molecular process
10.1016/s0092-8674(00)81280-5 · ExternalCitation · doi-reference
Dendritic organization of actin comet tails
10.1016/s0960-9822(01)00022-7 · ExternalCitation · doi-reference
Self-polarization and directional motility of cytoplasm
10.1016/s0960-9822(99)80042-6 · ExternalCitation · doi-reference
Tying a molecular knot with optical tweezers
10.1038/20894 · ExternalCitation · doi-reference
Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness
10.1038/385537a0 · ExternalCitation · doi-reference
Forming the cell rear first: breaking cell symmetry to trigger directed cell migration
10.1038/ncb0710-628 · ExternalCitation · doi-reference
Long-range self-organization of cytoskeletal myosin II filament stacks
10.1038/ncb3466 · ExternalCitation · doi-reference
Fiji: an open-source platform for biological-image analysis
10.1038/nmeth.2019 · ExternalCitation · doi-reference
Minimal model for spontaneous cell polarization and edge activity in oscillating, rotating and migrating cells
10.1038/nphys3615 · ExternalCitation · doi-reference
Physical influences of the extracellular environment on cell migration
10.1038/nrm3897 · ExternalCitation · doi-reference
Membrane tension induces F-actin reorganization and flow in a biomimetic model cortex
10.1038/s42003-023-04684-7 · ExternalCitation · doi-reference
F-actin buckling coordinates contractility and severing in a biomimetic actomyosin cortex
10.1073/pnas.1214753109 · ExternalCitation · doi-reference
Balance between cell-substrate adhesion and myosin contraction determines the frequency of motility initiation in fish keratocytes
10.1073/pnas.1417257112 · ExternalCitation · doi-reference
Fiber networks amplify active stress
10.1073/pnas.1514208113 · ExternalCitation · doi-reference
Deterministic actin waves as generators of cell polarization cues
10.1073/pnas.1907845117 · ExternalCitation · doi-reference
Stick-slip model for actin-driven cell protrusions, cell polarization, and crawling
10.1073/pnas.2011785117 · ExternalCitation · doi-reference
Using point cloud data to identify, trace, and regularize the outlines of buildings
10.1080/01431161.2015.1131868 · ExternalCitation · doi-reference
Flexural rigidity of microtubules and actin filaments measured from thermal fluctuations in shape
10.1083/jcb.120.4.923 · ExternalCitation · doi-reference
Actin-myosin network reorganization breaks symmetry at the cell rear to spontaneously initiate polarized cell motility
10.1083/jcb.200706012 · ExternalCitation · doi-reference
Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed
10.1083/jcb.200810060 · ExternalCitation · doi-reference
Collective Langevin dynamics of flexible cytoskeletal fibers
10.1088/1367-2630/9/11/427 · ExternalCitation · doi-reference
Active gel model for one-dimensional cell migration coupling actin flow and adhesion dynamics
10.1088/1367-2630/ad63c5 · ExternalCitation · doi-reference
Shaping up synthetic cells
10.1088/1478-3975/aab923 · ExternalCitation · doi-reference
Arp2/3 complex inhibition radically alters lamellipodial actin architecture, suspended cell shape, and the cell spreading process
10.1091/mbc.e14-07-1244 · ExternalCitation · doi-reference
A hybrid stochastic-deterministic mechanochemical model of cell polarization
10.1091/mbc.e19-09-0549 · ExternalCitation · doi-reference
From simple to detailed models for cell polarization
10.1098/rstb.2013.0003 · ExternalCitation · doi-reference
Cell motility resulting from spontaneous polymerization waves
10.1103/physrevlett.107.258103 · ExternalCitation · doi-reference
Contraction-driven cell motility
10.1103/physrevlett.111.108102 · ExternalCitation · doi-reference
Interplay between mechanosensitive adhesions and membrane tension regulates cell motility
10.1103/prxlife.1.023007 · ExternalCitation · doi-reference
Modeling semiflexible polymer networks
10.1103/revmodphys.86.995 · ExternalCitation · doi-reference
High-resolution cell outline segmentation and tracking from phase-contrast microscopy images
10.1111/j.1365-2818.2011.03558.x · ExternalCitation · doi-reference
Stick-slip dynamics of cell adhesion triggers spontaneous symmetry breaking and directional migration of mesenchymal cells on one-dimensional lines
10.1126/sciadv.aau5670 · ExternalCitation · doi-reference
Synthetic control of actin polymerization and symmetry breaking in active protocells
10.1126/sciadv.adk9731 · ExternalCitation · doi-reference
Electrochemical control of cell and tissue polarity
10.1146/annurev-cellbio-100913-013357 · ExternalCitation · doi-reference
A minimal cell model for lamellipodia-based cellular dynamics and migration
10.1242/jcs.260744 · ExternalCitation · doi-reference
Coordinating cell polarization and morphogenesis through mechanical feedback
10.1371/journal.pcbi.1007971 · ExternalCitation · doi-reference
Simulations of dynamically cross-linked actin networks: morphology, rheology, and hydrodynamic interactions
10.1371/journal.pcbi.1009240 · ExternalCitation · doi-reference
Discrete mechanical model of lamellipodial actin network implements molecular clutch mechanism and generates arcs and microspikes
10.1371/journal.pcbi.1009506 · ExternalCitation · doi-reference
Effects of adhesion dynamics and substrate compliance on the shape and motility of crawling cells
10.1371/journal.pone.0064511 · ExternalCitation · doi-reference
Attachment conditions control actin filament buckling and the production of forces
10.1529/biophysj.106.094672 · ExternalCitation · doi-reference
Integrins modulate T cell receptor signaling by constraining actin flow at the immunological synapse
10.3389/fimmu.2018.00025 · ExternalCitation · doi-reference
Acto-myosin based response to stiffness and rigidity sensing
10.4161/cam.5.1.13281 · ExternalCitation · doi-reference
Myosin motors fragment and compact membrane-bound actin filaments
10.7554/elife.00116 · ExternalCitation · doi-reference