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References from Deletion of the Candida albicans TLO gene family using CRISPR-Cas9 mutagenesis allows characterisation of functional differences in α-, β- and γ- TLO gene function. Local targets link to admitted publications; unresolved targets remain external evidence.
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Unresolved reference
2022 · External reference
Evolution of pathogenicity and sexual reproduction in eight Candida genomes
10.1038/nature08064 · 2009 · External reference
Comparative genomics of the fungal pathogens Candida dubliniensis and Candida albicans
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Candida albicans pathogenicity mechanisms.
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The Tlo proteins are stoichiometric components of Candida albicans mediator anchored via the Med3 subunit
10.1128/ec.00095-12 · 2012 · External reference
Function and regulation of the Mediator complex
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The Mediator complex and transcription elongation
10.1016/j.bbagrm.2012.08.017 · 2013 · External reference
Amplification of TLO Mediator subunit genes facilitate filamentous growth in Candida Spp.
10.1371/journal.pgen.1006373 · 2016 · External reference
Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex
10.1093/nar/gkn349 · 2008 · External reference
Twenty years of Mediator complex structural studies
10.1042/bst20180608 · 2019 · External reference
The functions of Mediator in Candida albicans support a role in shaping species-specific gene expression
10.1371/journal.pgen.1002613 · 2012 · External reference
A functional portrait of Med7 and the mediator complex in Candida albicans.
10.1371/journal.pgen.1004770 · 2014 · External reference
Differential regulation of white-opaque switching by individual subunits of Candida albicans mediator
10.1128/ec.00137-13 · 2013 · External reference
Genetic and phenotypic intra-species variation in Candida albicans
10.1101/gr.174623.114 · 2015 · External reference
Real-time evolution of a subtelomeric gene family in Candida albicans
10.1534/genetics.115.177451 · 2015 · External reference
Architectural groups of a subtelomeric gene family evolve along distinct paths in Candida albicans
10.1093/g3journal/jkac283 · 2022 · External reference
Role of Mediator in virulence and antifungal drug resistance in pathogenic fungi
10.1007/s00294-019-00932-8 · 2019 · External reference
The three clades of the telomere-associated TLO gene family of Candida albicans have different splicing, localization, and expression features
10.1128/ec.00230-12 · 2012 · External reference
Expansion of the TLO gene family enhances the virulence of Candida species
10.1371/journal.pone.0200852 · 2018 · External reference
Telomeric ORFs (TLOs) in Candida spp. encode mediator subunits that regulate distinct virulence traits.
10.1371/journal.pgen.1004658 · 2014 · External reference
Telomeric ORFS in Candida albicans: does mediator tail wag the yeast?
10.1371/journal.ppat.1004614 · 2015 · External reference
Functional diversification accompanies gene family expansion of MED2 homologs in Candida albicans.
10.1371/journal.pgen.1007326 · 2018 · External reference
Aneuploid chromosomes are highly unstable during DNA transformation of Candida albicans
10.1128/ec.00209-09 · 2009 · External reference
The role of the Mediator complex in fungal pathogenesis and response to antifungal agents
2023 · External reference
Candida albicans dispersed cells are developmentally distinct from biofilm and planktonic cells.
10.1128/mbio.01338-18 · 2018 · External reference
RNA enrichment method for quantitative transcriptional nalysis of pathogens in vivo applied to the fungus Candida albicans
10.1128/mbio.00942-15 · 2015 · External reference
Fungal mediator tail subunits contain classical transcriptional activation domains
10.1128/mcb.01508-14 · 2015 · External reference
An efficient, rapid, and recyclable system for CRISPR-mediated genome editing in Candida albicans
10.1128/mspheredirect.00149-17 · 2017 · External reference
Isogenic strain construction and gene targeting in Candida dubliniensis
10.1128/jb.183.9.2859-2865.2001 · 2001 · External reference
FastQ Screen: A tool for multi-genome mapping and quality control.
10.12688/f1000research.15931.1 · 2018 · External reference
Fast gapped-read alignment with Bowtie 2.
10.1038/nmeth.1923 · 2012 · External reference
Twelve years of SAMtools and BCFtools.
10.1093/gigascience/giab008 · 2021 · External reference
Integrative genomics viewer
10.1038/nbt.1754 · 2011 · External reference
Integrative Genomics Viewer (IGV): High-performance genomics data visualization and exploration.
10.1093/bib/bbs017 · 2013 · External reference
YMAP: a pipeline for visualization of copy number variation and loss of heterozygosity in eukaryotic pathogens
2014 · External reference
Completing bacterial genome assemblies with multiplex MinION sequencing
2017 · External reference
NanoPack: visualizing and processing long-read sequencing data
10.1093/bioinformatics/bty149 · 2018 · External reference
Versatile and open software for comparing large genomes
10.1186/gb-2004-5-2-r12 · 2004 · External reference
Minimap2: pairwise alignment for nucleotide sequences
10.1093/bioinformatics/bty191 · 2018 · External reference
The Sequence Alignment/Map format and SAMtools
10.1093/bioinformatics/btp352 · 2009 · External reference
BEDTools: a flexible suite of utilities for comparing genomic features
10.1093/bioinformatics/btq033 · 2010 · External reference
Separation of yeast chromosome-sized DNAs by pulsed-field gradient gel electrophoresis
10.1016/0092-8674(84)90301-5 · 1984 · External reference
Tetracycline-inducible gene expression and gene deletion in Candida albicans
10.1128/ec.4.8.1328-1342.2005 · 2005 · External reference
Analyzing real-time PCR data by the comparative C(T) method.
10.1038/nprot.2008.73 · 2008 · External reference
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
10.1186/s13059-014-0550-8 · 2014 · External reference
The Candida Genome Database (CGD): incorporation of Assembly 22, systematic identifiers and visualization of high throughput sequencing data.
10.1093/nar/gkw924 · 2017 · External reference
The Gene Ontology resource: enriching a GOld mine.
10.1093/nar/gkaa1113 · 2021 · External reference
Gene ontology: tool for the unification of biology. The Gene Ontology Consortium.
10.1038/75556 · 2000 · External reference
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
10.1073/pnas.0506580102 · 2005 · External reference
Chromatin particle spectrum analysis: a method for comparative chromatin structure analysis using paired-end mode next-generation DNA sequencing
10.1093/nar/gkq1183 · 2011 · External reference
fastp: an ultra-fast all-in-one FASTQ preprocessor
10.1093/bioinformatics/bty560 · 2018 · External reference
Model-based analysis of ChIP-Seq (MACS).
10.1186/gb-2008-9-9-r137 · 2008 · External reference
deepTools2: a next generation web server for deep-sequencing data analysis
10.1093/nar/gkw257 · 2016 · External reference
Integrated genome browser: visual analytics platform for genomics
10.1093/bioinformatics/btw069 · 2016 · External reference
Identification of SkpA-CulA-F-box E3 ligase complexes in pathogenic Aspergilli
10.1016/j.fgb.2020.103396 · 2020 · External reference
