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References from Oocyte vitrification disrupts zygotic genome activation in embryos by impairing maternal spliceosome translation and Crxos splicing. Local targets link to admitted publications; unresolved targets remain external evidence.
Oocyte cryopreservation: where are we now?
10.1093/humupd/dmw007 · 2016 · External reference
Review of human oocyte cryopreservation in ART programs: Current challenges and opportunities
10.1016/j.cryobiol.2023.104590 · 2023 · External reference
Prospective randomized comparison of human oocyte cryopreservation with slow-rate freezing or vitrification
10.1016/j.fertnstert.2009.12.065 · 2010 · External reference
Obstetric and perinatal outcome of babies born from vitrified oocytes
10.1016/j.fertnstert.2014.06.019 · 2014 · External reference
Six-year follow-up of children born from vitrified oocytes
10.1016/j.rbmo.2020.11.005 · 2021 · External reference
Improving vitrification efficiency of human in vitro matured oocytes by the addition of LEA proteins
10.1093/humrep/deae065 · 2024 · External reference
The application of apoptotic inhibitor in apoptotic pathways of MII stage porcine oocytes after vitrification
10.1111/rda.12772 · 2016 · External reference
The combination treatment of cholesterol-loaded methyl-β-cyclodextrin and methyl-β-cyclodextrin significantly improves the fertilization capacity of vitrified bovine oocytes by protecting fertilization protein JUNO
10.1111/rda.13890 · 2021 · External reference
Developmental competence of in vitro matured ovine oocytes vitrified in solutions with different concentrations of trehalose
10.1111/rda.13221 · 2018 · External reference
The walnut-derived peptide TW-7 improves mouse parthenogenetic embryo development of vitrified MII oocytes potentially by promoting histone lactylation
10.1186/s40104-024-01045-0 · 2024 · External reference
TW-7 Alleviate Apoptosis of Embryos Derived From Vitrified MII Oocytes by Downregulation of JNK Signaling in Mice
2025 · External reference
The maternal-to-zygotic transition: reprogramming of the cytoplasm and nucleus
10.1038/s41576-024-00792-0 · 2025 · External reference
Degradation and translation of maternal mRNA for embryogenesis
10.1016/j.tig.2023.12.008 · 2024 · External reference
The translational oscillation in oocyte and early embryo development
10.1093/nar/gkad996 · 2023 · External reference
Profiling and functional characterization of maternal mRNA translation during mouse maternal-to-zygotic transition
10.1126/sciadv.abj3967 · 2022 · External reference
Maternal factor OTX2 regulates human embryonic genome activation and early development
10.1038/s41588-025-02350-8 · 2025 · External reference
OBOX regulates mouse zygotic genome activation and early development
10.1038/s41586-023-06428-3 · 2023 · External reference
Translatome and transcriptome co-profiling reveals a role of TPRXs in human zygotic genome activation
2022 · External reference
Maternal TDP-43 interacts with RNA Pol II and regulates zygotic genome activation
10.1038/s41467-023-39924-1 · 2023 · External reference
Maternal KLF17 controls zygotic genome activation by acting as a messenger for RNA Pol II recruitment in mouse embryos
10.1016/j.devcel.2024.01.013 · 2024 · External reference
Zygotic Splicing Activation of the Transcriptome is a Crucial Aspect of Maternal-to-Zygotic Transition and Required for the Conversion from Totipotency to Pluripotency
10.1002/advs.202308496 · 2024 · External reference
Alternative splicing of CARM1 regulated by LincGET-guided paraspeckles biases the first cell fate in mammalian early embryos
10.1038/s41594-024-01292-9 · 2024 · External reference
The effects of vitrification on oocyte quality
10.1093/biolre/ioab239 · 2022 · External reference
Shorter protocols for vitrification and post-warming dilution of human oocytes and embryos: a narrative review
10.1016/j.rbmo.2025.104857 · 2025 · External reference
The protective role of antifreeze protein 3 on the structure and function of mature mouse oocytes in vitrification
10.1016/j.cryobiol.2014.09.006 · 2014 · External reference
Recovery of spindle morphology and mitochondrial function through extended culture after vitrification-warming of bovine oocytes
10.1016/j.theriogenology.2022.06.021 · 2022 · External reference
Effect of glutathione addition on vitrification of ovine oocytes
10.1016/j.theriogenology.2025.117412 · 2025 · External reference
C-Phycocyanin improves the quality of goat oocytes after in vitro maturation and vitrification
10.1016/j.theriogenology.2024.04.004 · 2024 · External reference
Melatonin promotes in vitro development of vitrified-warmed mouse GV oocytes, potentially by modulating phosphorylation of Drp1
10.3389/fvets.2021.752001 · 2021 · External reference
Mitophagy is involved in the mitochondrial dysfunction of vitrified porcine oocytes
10.1002/mrd.23472 · 2021 · External reference
2-Aminoethyl diphenylborinate mitigates damage from the endoplasmic reticulum of vitrified bovine oocyte
10.1016/j.theriogenology.2025.02.019 · 2025 · External reference
Ultrastructural markers of quality in human mature oocytes vitrified using cryoleaf and cryoloop
10.1016/s1472-6483(10)60280-5 · 2009 · External reference
Oxidative Stress and Oocyte Cryopreservation: Recent Advances in Mitigation Strategies Involving Antioxidants
10.3390/cells11223573 · 2022 · External reference
m6A-binding YTHDF proteins promote stress granule formation
10.1038/s41589-020-0524-y · 2020 · External reference
Translation landscape of stress granules
2025 · External reference
Principles and Properties of Stress Granules
10.1016/j.tcb.2016.05.004 · 2016 · External reference
Transcriptome and translatome co-evolution in mammals
10.1038/s41586-020-2899-z · 2020 · External reference
Kick-starting the zygotic genome: licensors, specifiers, and beyond
10.1038/s44319-024-00223-5 · 2024 · External reference
Systematic evaluation of retroviral LTRs as cis-regulatory elements in mouse embryos
10.1016/j.celrep.2024.113775 · 2024 · External reference
Chromatin accessibility landscape of mouse early embryos revealed by single-cell NanoATAC-seq2
2025 · External reference
Zygotic genome activation by the totipotency pioneer factor Nr5a2
10.1126/science.abn7478 · 2022 · External reference
Maternal factor NELFA drives a 2C-like state in mouse embryonic stem cells
10.1038/s41556-019-0453-8 · 2020 · External reference
Maternal PRDM10 activates essential genes for oocyte-to-embryo transition
10.1038/s41467-025-56991-8 · 2025 · External reference
Proteomic profile of mouse oocytes after vitrification: A quantitative analysis based on 4D label-free technique
10.1016/j.theriogenology.2022.04.028 · 2022 · External reference
Splicing control by PHF5A is crucial for melanoma cell survival
10.1111/cpr.13741 · 2025 · External reference
Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex
10.1038/ncomms15522 · 2017 · External reference
Slow freezing and vitrification differentially modify the gene expression profile of human metaphase II oocytes
10.1093/humrep/des153 · 2012 · External reference
Comparison of oocyte vitrification using a semi-automated or a manual closed system in human siblings: survival and transcriptomic analyses
10.1186/s13048-022-01064-3 · 2022 · External reference
Metformin alleviates cryoinjuries in porcine oocytes by reducing membrane fluidity through the suppression of mitochondrial activity
10.1038/s42003-024-06631-6 · 2024 · External reference
Ultrasensitive Ribo-seq reveals translational landscapes during mammalian oocyte-to-embryo transition and pre-implantation development
10.1038/s41556-022-00928-6 · 2022 · External reference
Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition
10.1038/nature19360 · 2016 · External reference
Tead4 and Tfap2c generate bipotency and a bistable switch in totipotent embryos to promote robust lineage diversification
10.1038/s41594-024-01311-9 · 2024 · External reference
Mapping putative enhancers in mouse oocytes and early embryos reveals TCF3/12 as key folliculogenesis regulators
10.1038/s41556-024-01422-x · 2024 · External reference
Transcription Factor TCF12-Mediated Maternal Gene Expressions in Mouse Oocyte Are Prerequisites of Successful Fertilisation and Zygotic Genome Activation
2026 · External reference
Unreprogrammed H3K9me3 prevents minor zygotic genome activation and lineage commitment in SCNT embryos
10.1038/s41467-023-40496-3 · 2023 · External reference
Decoding post-transcriptional regulatory networks by RNA-linked CRISPR screening in human cells
10.1038/s41592-025-02702-6 · 2025 · External reference
Structural basis of branch site recognition by the human spliceosome
10.1126/science.abm4245 · 2022 · External reference
Crystal structures of the Lsm complex bound to the 3’ end sequence of U6 small nuclear RNA
10.1038/nature12803 · 2014 · External reference
How is precursor messenger RNA spliced by the spliceosome?
10.1146/annurev-biochem-013118-111024 · 2020 · External reference
Intact structure of EGAM1 homeoproteins and basic amino acid residues in the common homeodomain of EGAM1 and EGAM1C contribute to their nuclear localization in mouse embryonic stem cells
10.1016/j.jbiosc.2013.02.007 · 2013 · External reference
Preferential emergence of cell types expressing markers for primitive endoderm lineages in mouse embryonic stem cells expressing exogenous EGAM1 homeoprotein
10.1016/j.jbiosc.2012.04.012 · 2012 · External reference
Coordinated regulation of RNA polymerase II pausing and elongation progression by PAF1
10.1126/sciadv.abm5504 · 2022 · External reference
Structures of co-transcriptional RNA capping enzymes on paused transcription complex
10.1038/s41467-024-48963-1 · 2024 · External reference
Acute and rapid degradation of endogenous proteins by Trim-Away
10.1038/s41596-018-0028-3 · 2018 · External reference
A framework for TRIM21-mediated protein depletion in early mouse embryos: recapitulation of Tead4 null phenotype over three days
10.1186/s12864-019-6106-2 · 2019 · External reference
Methods for Characterization of Alternative RNA Splicing
10.1007/978-1-4939-3378-5_18 · 2016 · External reference
Single-cell transcriptome and translatome dual-omics reveals potential mechanisms of human oocyte maturation
10.1038/s41467-022-32791-2 · 2022 · External reference
Decoding the Molecular Landscape of Prepubertal Oocyte Maturation: GTPBP4 as a Key Driver of In Vitro Developmental Competence
2025 · External reference
rMATS: robust and flexible detection of differential alternative splicing from replicate RNA-Seq data
10.1073/pnas.1419161111 · 2014 · External reference
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
10.1016/j.molcel.2010.05.004 · 2010 · External reference
Transcription of MERVL retrotransposons is required for preimplantation embryo development
10.1038/s41588-023-01324-y · 2023 · External reference
Accurate structure prediction of biomolecular interactions with AlphaFold 3
10.1038/s41586-024-07487-w · 2024 · External reference
SMART v10: three decades of the protein domain annotation resource
10.1093/nar/gkaf1023 · 2026 · External reference
