Research graph
References from Identifying shared polygenic risk across cancers. Local targets link to admitted publications; unresolved targets remain external evidence.
Familial Risk and Heritability of Cancer Among Twins in Nordic Countries
10.1001/jama.2015.17703 · 2016 · External reference
Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses
10.1038/s41588-020-0609-2 · 2020 · External reference
10.1038/s41588-018-0142-8
10.1038/s41588-018-0142-8 · External reference
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes
10.1038/ng.3892 · 2017 · External reference
A novel TP53 variant (rs78378222 A > C) in the polyadenylation signal is associated with increased cancer susceptibility: evidence from a meta-analysis
10.18632/oncotarget.9056 · 2016 · External reference
Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types
10.1093/jnci/djv279 · 2015 · External reference
Shared heritability and functional enrichment across six solid cancers
10.1038/s41467-018-08054-4 · 2019 · External reference
Genome-wide analyses characterize shared heritability among cancers and identify novel cancer susceptibility regions
10.1093/jnci/djad043 · 2023 · External reference
Cross-cancer evaluation of polygenic risk scores for 16 cancer types in two large cohorts
10.1038/s41467-021-21288-z · 2021 · External reference
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer
10.1038/ng.3826 · 2017 · External reference
FinnGen provides genetic insights from a well-phenotyped isolated population
10.1038/s41586-022-05473-8 · 2023 · External reference
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
10.1038/ng.3211 · 2015 · External reference
UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age
10.1371/journal.pmed.1001779 · 2015 · External reference
JointPRS: A data-adaptive framework for multi-population genetic risk prediction incorporating genetic correlation
10.1038/s41467-025-59243-x · 2025 · External reference
A Powerful Approach to Estimating Annotation-Stratified Genetic Covariance via GWAS Summary Statistics
10.1016/j.ajhg.2017.11.001 · 2017 · External reference
SUPERGNOVA: local genetic correlation analysis reveals heterogeneous etiologic sharing of complex traits
10.1186/s13059-021-02478-w · 2021 · External reference
Benchmarking of local genetic correlation estimation methods using summary statistics from genome-wide association studies
10.1093/bib/bbad407 · 2023 · External reference
Nealelab/UK_Biobank_GWAS: v2
2023 · External reference
An integrated framework for local genetic correlation analysis
10.1038/s41588-022-01017-y · 2022 · External reference
Functional mapping and annotation of genetic associations with FUMA
10.1038/s41467-017-01261-5 · 2017 · External reference
A fast and robust Bayesian nonparametric method for prediction of complex traits using summary statistics
10.1371/journal.pgen.1009697 · 2021 · External reference
Using clinical and genetic risk factors for risk prediction of 8 cancers in the UK Biobank
2024 · External reference
PLINK: a tool set for whole-genome association and population-based linkage analyses
10.1086/519795 · 2007 · External reference
Robust pleiotropy-decomposed polygenic scores identify distinct contributions to elevated coronary artery disease polygenic risk
2025 · External reference
10.1101/2025.06.16.25329688
10.1101/2025.06.16.25329688 · External reference
KEGG: kyoto encyclopedia of genes and genomes
10.1093/nar/28.1.27 · 2000 · External reference
Identifying proteomic risk factors for cancer using prospective and exome analyses of 1463 circulating proteins and risk of 19 cancers in the UK Biobank
10.1038/s41467-024-48017-6 · 2024 · External reference
Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma
10.1038/ncomms12510 · 2016 · External reference
A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2
10.1038/ng.424 · 2009 · External reference
Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types
10.1158/2159-8290.cd-15-1227 · 2016 · External reference
A genome-wide association screen identifies regions on chromosomes 1q25 and 7p21 as risk loci for sporadic prostate cancer
10.1038/sj.pcan.4501010 · 2008 · External reference
Mendelian randomization study of sleep traits and risk of colorectal cancer
10.1038/s41598-024-83693-w · 2025 · External reference
Type 2 Diabetes and Cancer: An Umbrella Review of Observational and Mendelian Randomization Studies
10.1158/1055-9965.epi-20-1245 · 2021 · External reference
Overlapping genetic architecture between Parkinson disease and melanoma
10.1007/s00401-019-02110-z · 2020 · External reference
Common genetic polymorphisms contribute to the association between chronic lymphocytic leukaemia and non-melanoma skin cancer
10.1093/ije/dyab042 · 2021 · External reference
8q24.21 Locus: A Paradigm to Link Non-Coding RNAs, Genome Polymorphisms and Cancer
10.3390/ijms22031094 · 2021 · External reference
Pathologic HDAC1/c-Myc signaling axis is responsible for angiotensinogen transcription and hypertension induced by high-fat diet
10.1016/j.biopha.2023.114926 · 2023 · External reference
Familial Risk and Heritability of Cancer Among Twins in Nordic Countries
10.1001/jama.2015.17703 · ExternalCitation · doi-reference
Overlapping genetic architecture between Parkinson disease and melanoma
10.1007/s00401-019-02110-z · ExternalCitation · doi-reference
A Powerful Approach to Estimating Annotation-Stratified Genetic Covariance via GWAS Summary Statistics
10.1016/j.ajhg.2017.11.001 · ExternalCitation · doi-reference
Pathologic HDAC1/c-Myc signaling axis is responsible for angiotensinogen transcription and hypertension induced by high-fat diet
10.1016/j.biopha.2023.114926 · ExternalCitation · doi-reference
Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma
10.1038/ncomms12510 · ExternalCitation · doi-reference
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
10.1038/ng.3211 · ExternalCitation · doi-reference
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer
10.1038/ng.3826 · ExternalCitation · doi-reference
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes
10.1038/ng.3892 · ExternalCitation · doi-reference
A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2
10.1038/ng.424 · ExternalCitation · doi-reference
Functional mapping and annotation of genetic associations with FUMA
10.1038/s41467-017-01261-5 · ExternalCitation · doi-reference
Shared heritability and functional enrichment across six solid cancers
10.1038/s41467-018-08054-4 · ExternalCitation · doi-reference
Cross-cancer evaluation of polygenic risk scores for 16 cancer types in two large cohorts
10.1038/s41467-021-21288-z · ExternalCitation · doi-reference
Identifying proteomic risk factors for cancer using prospective and exome analyses of 1463 circulating proteins and risk of 19 cancers in the UK Biobank
10.1038/s41467-024-48017-6 · ExternalCitation · doi-reference
JointPRS: A data-adaptive framework for multi-population genetic risk prediction incorporating genetic correlation
10.1038/s41467-025-59243-x · ExternalCitation · doi-reference
FinnGen provides genetic insights from a well-phenotyped isolated population
10.1038/s41586-022-05473-8 · ExternalCitation · doi-reference
10.1038/s41588-018-0142-8
10.1038/s41588-018-0142-8 · ExternalCitation · doi-reference
Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses
10.1038/s41588-020-0609-2 · ExternalCitation · doi-reference
An integrated framework for local genetic correlation analysis
10.1038/s41588-022-01017-y · ExternalCitation · doi-reference
Mendelian randomization study of sleep traits and risk of colorectal cancer
10.1038/s41598-024-83693-w · ExternalCitation · doi-reference
A genome-wide association screen identifies regions on chromosomes 1q25 and 7p21 as risk loci for sporadic prostate cancer
10.1038/sj.pcan.4501010 · ExternalCitation · doi-reference
PLINK: a tool set for whole-genome association and population-based linkage analyses
10.1086/519795 · ExternalCitation · doi-reference
Benchmarking of local genetic correlation estimation methods using summary statistics from genome-wide association studies
10.1093/bib/bbad407 · ExternalCitation · doi-reference
Common genetic polymorphisms contribute to the association between chronic lymphocytic leukaemia and non-melanoma skin cancer
10.1093/ije/dyab042 · ExternalCitation · doi-reference
Genome-wide analyses characterize shared heritability among cancers and identify novel cancer susceptibility regions
10.1093/jnci/djad043 · ExternalCitation · doi-reference
Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types
10.1093/jnci/djv279 · ExternalCitation · doi-reference
KEGG: kyoto encyclopedia of genes and genomes
10.1093/nar/28.1.27 · ExternalCitation · doi-reference
10.1101/2025.06.16.25329688
10.1101/2025.06.16.25329688 · ExternalCitation · doi-reference
Type 2 Diabetes and Cancer: An Umbrella Review of Observational and Mendelian Randomization Studies
10.1158/1055-9965.epi-20-1245 · ExternalCitation · doi-reference
Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types
10.1158/2159-8290.cd-15-1227 · ExternalCitation · doi-reference
SUPERGNOVA: local genetic correlation analysis reveals heterogeneous etiologic sharing of complex traits
10.1186/s13059-021-02478-w · ExternalCitation · doi-reference
A fast and robust Bayesian nonparametric method for prediction of complex traits using summary statistics
10.1371/journal.pgen.1009697 · ExternalCitation · doi-reference
UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age
10.1371/journal.pmed.1001779 · ExternalCitation · doi-reference
A novel TP53 variant (rs78378222 A > C) in the polyadenylation signal is associated with increased cancer susceptibility: evidence from a meta-analysis
10.18632/oncotarget.9056 · ExternalCitation · doi-reference
8q24.21 Locus: A Paradigm to Link Non-Coding RNAs, Genome Polymorphisms and Cancer
10.3390/ijms22031094 · ExternalCitation · doi-reference
